专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US08124409B2 Utilizing liver cell line QSG-7701 to be infected with hepatitis B virus 失效
标题翻译：利用肝细胞系QSG-7701感染乙型肝炎病毒
公开(公告)号：US08124409B2
公开(公告)日：2012-02-28
申请号：US12523085
申请日：2008-01-29
申请人： Xiaoben Pan , Lai Wei
发明人： Xiaoben Pan , Lai Wei
IPC分类号： C12N5/10 , C07N7/06
CPC分类号： C12N7/00 , C12N2730/10151
摘要： The use of the liver cell line QSG-7701 for HBV infection includes the following steps: directly infecting QSG-7701 cells with purified HBV particles and facilitating the infection by DMSO and/or PEG treatment. The easily available QSG-7701 liver cell line may not require pre-differentiation induction and is naturally susceptible for HBV infection. This cell line provides near normal physiological conditions for HBV infection, especially the infection conditions that are characterized with Chinese origin. This cell line is suitable for investigating the life cycle of HBV. Therefore, this cell line is useful for the investigation of viral infection processes and for the development of drugs that specifically target these processes.
摘要翻译：肝细胞系QSG-7701用于HBV感染的方法包括以下步骤：用纯化的HBV颗粒直接感染QSG-7701细胞，并促进通过DMSO和/或PEG处理的感染。容易获得的QSG-7701肝细胞系可能不需要预分化诱导，并且对HBV感染天然易感。该细胞系为HBV感染提供接近正常的生理条件，特别是以中国血清为特征的感染病症。该细胞系适用于调查HBV的生命周期。因此，这种细胞系可用于病毒感染过程的研究和用于开发专门针对这些过程的药物。

12. 发明申请

US20110205638A1 ZOOM LENS 有权
标题翻译：变焦镜头
公开(公告)号：US20110205638A1
公开(公告)日：2011-08-25
申请号：US13010100
申请日：2011-01-20
申请人： Lai WEI
发明人： Lai WEI
IPC分类号： G02B15/14
CPC分类号： G02B15/177
摘要： A zoom lens includes sequentially from an object side a first lens group having a negative refractive power; a diaphragm; and a second lens group having a positive refractive power. Zoom from a wide angle edge to a telephoto edge is performed by displacement of the second lens group along an optical axis, toward the object side. Correction of imaging plane variation accompanying the zoom, is performed by displacement of the first lens group along the optical axis. The second lens group includes sequentially from the object side, a positive first lens having at least on aspheric surface and a positive second lens. Furthermore, a first condition υd21>63 and a second condition υd22>70 are satisfied, υd21 being the Abbe number for a d-line in the first lens of the second lens group and υd22 being the Abbe number for a d-line in the second lens of the second lens group.
摘要翻译：变焦透镜从物体侧依次包括具有负屈光力的第一透镜组; 隔膜以及具有正屈光力的第二透镜组。通过第二透镜组沿着光轴朝向物体侧的位移，从广角边缘到远摄边缘的放大进行。通过第一透镜组沿着光轴的位移来进行伴随变焦的成像面变化的校正。第二透镜组从物体侧依次包括具有至少非球面的正的第一透镜和正的第二透镜。此外，满足第一条件υd21> 63和第二条件υd22> 70，υd21是第二透镜组的第一透镜中的d线的阿贝数，υd22是第二透镜组中的d线的阿贝数第二透镜组的第二透镜。

13. 发明申请

US20110188117A1 ANTI-VIBRATION ZOOM LENS OPTICS 有权
标题翻译：抗振动变焦镜头光学
公开(公告)号：US20110188117A1
公开(公告)日：2011-08-04
申请号：US13016045
申请日：2011-01-28
申请人： Akio Arakawa , Lai Wei
发明人： Akio Arakawa , Lai Wei
IPC分类号： G02B27/64 , G02B15/14
CPC分类号： G02B15/14 , G02B27/64
摘要： The present invention is directed to provide an anti-vibration zoom lens optics designed to bring about capabilities of reducing an effective aperture of one of lens groups displaceable for anti-vibration compensation to permit downsizing of anti-vibration mechanism, and of avoiding complicating the lens mechanism by virtue of the optics design simply of four of the lens groups where a unit associated with an aperture stop and an anti-vibration unit can be appropriately spaced apart from each other without interference between driving mechanisms for both the units. The four groups of lens pieces include the leading or first lens group of positive refractivity, the succeeding second lens group of negative refractivity, the third lens group of positive refractivity, and the trailing or fourth lens group of positive refractivity all arranged in this order from the front end closest to the object to the rearmost, where the fourth lens group include three subsets of lens pieces, namely, the leading or first subset, the succeeding or second subset, and the trailing or third subset all arranged in this order from the front end closest to the object to the rearmost, and the second subset of lens pieces are moved perpendicular to the optical axis to compensate for blur in the imaging plane.
摘要翻译：本发明旨在提供一种防振变焦透镜光学器件，其被设计成具有减小可移动以用于抗振动补偿的透镜组之一的有效孔径的能力，从而允许减小抗振机构的尺寸，并避免使透镜复杂化通过简单地通过光学设计的四个透镜组的机构，其中与孔径光阑和抗振单元相关联的单元可以彼此适当地间隔开，而两个单元的驱动机构之间没有干涉。四组透镜片包括正折射率的前导透镜组或第一透镜组，负折射率的后续第二透镜组，正折射率的第三透镜组和正折射率的后第四透镜组均按照从最靠近物体到最后面的前端，其中第四透镜组包括三个透镜片的子集，即前导或第一子集，后续或第二子集，以及尾部或第三子集，全部以最靠近物体的前端到最后面，并且透镜片的第二子集垂直于光轴移动以补偿成像平面中的模糊。

14. 发明申请

US20100310605A1 ANTI-HCV VACCINE AND PREPARATION METHODS AND USES THEREOF 审中-公开
标题翻译：抗HCV疫苗及其制备方法及其用途
公开(公告)号：US20100310605A1
公开(公告)日：2010-12-09
申请号：US12809132
申请日：2007-12-18
申请人： Lai Wei , Yuan Tian
发明人： Lai Wei , Yuan Tian
IPC分类号： A61K39/29 , A61P31/14
CPC分类号： A61K39/29 , A61K39/12 , A61K2039/5256 , A61K2039/53 , C07K14/005 , C12N2710/10343 , C12N2770/24222 , C12N2770/24234
摘要： An anti-HCV vaccine, which is prepared through recombination of an NS gene in series, including NS3/NS4 and NS4/NS5, with an adenovirus vector. The preparation methods and uses of the anti-HCV vaccine.
摘要翻译：通过将NS基因（包括NS3 / NS4和NS4 / NS5）与腺病毒载体重组而制备的抗HCV疫苗。抗HCV疫苗的制备方法和用途。

15. 发明申请

US20140030219A1 METHODS OF DIAGNOSING AND TREATING AGE-RELATED MACULAR DEGENERATION 审中-公开
标题翻译：诊断和治疗老年相关性恶化的方法
公开(公告)号：US20140030219A1
公开(公告)日：2014-01-30
申请号：US13981368
申请日：2012-01-25
申请人： Lai Wei , Robert Nussenblatt , Baoying Liu , Chi-chao Chan
发明人： Lai Wei , Robert Nussenblatt , Baoying Liu , Chi-chao Chan
IPC分类号： C12Q1/68 , G01N33/68
CPC分类号： C12Q1/6883 , A61K38/1793 , C12Q2600/154 , G01N33/6893 , G01N2333/54 , G01N2440/12 , G01N2800/164 , G01N2800/50
摘要： The present invention is directed to methods of diagnosing the presence, severity, or predisposition for development of age-related macular degeneration in a patient based on the frequency of IL-17RC+ cells and or methylation of the promoter of IL17RC gene. Methods of treated age-related macular degeneration are also described.
摘要翻译：本发明涉及基于IL-17RC +细胞的频率和IL17RC基因启动子的甲基化诊断患者年龄相关性黄斑变性的存在，严重程度或倾向性的方法。还描述了治疗年龄相关性黄斑变性的方法。

16. 发明授权

US08184379B2 Zoom lens 有权
标题翻译：变焦镜头
公开(公告)号：US08184379B2
公开(公告)日：2012-05-22
申请号：US13010097
申请日：2011-01-20
申请人： Lai Wei
发明人： Lai Wei
IPC分类号： G02B15/14
CPC分类号： G02B15/177
摘要： A zoom lens includes sequentially from an object side a first lens group having a negative refractive power; a diaphragm; and a second lens group having a positive refractive power. Zoom from a wide angle edge to a telephoto edge is performed by displacement of the second lens group along an optical axis, toward the object side. Correction of imaging plane variation accompanying zoom, is performed by displacement of the first lens group along the optical axis. The second lens group includes a positive first lens disposed farthest on the object side and having at least one aspheric surface, and a cemented lens that includes a negative lens, a positive lens, and a negative lens. Furthermore, a first condition υd2p>75 is satisfied, υd2p being the Abbe number for a d-line in the positive lens included in the cemented lens of the second lens group.
摘要翻译：变焦透镜从物体侧依次包括具有负屈光力的第一透镜组; 隔膜以及具有正屈光力的第二透镜组。通过第二透镜组沿着光轴朝向物体侧的位移，从广角边缘到远摄边缘的放大进行。通过第一透镜组沿着光轴的位移来进行伴随变焦的成像平面变化的校正。第二透镜组包括在物体侧最远设置并具有至少一个非球面的正的第一透镜和包括负透镜，正透镜和负透镜的胶合透镜。此外，满足第一条件υd2p> 75，υd2p是包括在第二透镜组的胶合透镜中的正透镜中的d线的阿贝数。

17. 发明授权

US08085474B2 Zoom lens 有权
标题翻译：变焦镜头
公开(公告)号：US08085474B2
公开(公告)日：2011-12-27
申请号：US12512180
申请日：2009-07-30
申请人： Lai Wei
发明人： Lai Wei
IPC分类号： G02B15/14
CPC分类号： G02B15/177
摘要： A zoom lens includes, sequentially from an object side, a first lens group having a negative refractive power; and a second lens group having a positive refractive power, where focal length is varied by changing a distance between the first lens group and the second lens group, and a first conditional expression 0.8
摘要翻译：变焦透镜从物体侧顺序地包括具有负折光力的第一透镜组; 以及具有正折射力的第二透镜组，其中通过改变第一透镜组和第二透镜组之间的距离来改变焦距，并且满足第一条件表达式0.8 <| f1 / f2 | <1.0，f1是第一透镜组的焦距和f2是第二透镜组的焦距。

18. 发明申请

US20100055674A1 UTILIZING LIVER CELL LINE QSG-7701 TO BE INFECTED WITH HEPATITIS B VIRUS 失效
标题翻译：利用肝细胞系QSG-7701感染乙型肝炎病毒
公开(公告)号：US20100055674A1
公开(公告)日：2010-03-04
申请号：US12523085
申请日：2008-01-29
申请人： Xiaoben Pan , Lai Wei
发明人： Xiaoben Pan , Lai Wei
IPC分类号： C12Q1/70 , C12N5/00
CPC分类号： C12N7/00 , C12N2730/10151
摘要： The use of the liver cell line QSG-7701 for HBV infection includes the following steps: directly infecting QSG-7701 cells with purified HBV particles and facilitating the infection by DMSO and/or PEG treatment. The easily available QSG-7701 liver cell line may not require pre-differentiation induction and is naturally susceptible for HBV infection. This cell line provides near normal physiological conditions for HBV infection, especially the infection conditions that are characterized with Chinese origin. This cell line is suitable for investigating the life cycle of HBV. Therefore, this cell line is useful for the investigation of viral infection processes and for the development of drugs that specifically target these processes.
摘要翻译：肝细胞系QSG-7701用于HBV感染的方法包括以下步骤：用纯化的HBV颗粒直接感染QSG-7701细胞，并促进通过DMSO和/或PEG处理的感染。容易获得的QSG-7701肝细胞系可能不需要预分化诱导，并且对HBV感染天然易感。该细胞系为HBV感染提供接近正常的生理条件，特别是以中国血清为特征的感染病症。该细胞系适用于调查HBV的生命周期。因此，这种细胞系可用于病毒感染过程的研究和用于开发专门针对这些过程的药物。

19. 发明申请

US20100039710A1 ZOOM LENS 有权
标题翻译：变焦镜头
公开(公告)号：US20100039710A1
公开(公告)日：2010-02-18
申请号：US12512180
申请日：2009-07-30
申请人： Lai WEI
发明人： Lai WEI
IPC分类号： G02B15/177
CPC分类号： G02B15/177
摘要： A zoom lens includes, sequentially from an object side, a first lens group having a negative refractive power; and a second lens group having a positive refractive power, where focal length is varied by changing a distance between the first lens group and the second lens group, and a first conditional expression 0.8
摘要翻译：变焦透镜从物体侧顺序地包括具有负折光力的第一透镜组; 以及具有正折射力的第二透镜组，其中通过改变第一透镜组和第二透镜组之间的距离来改变焦距，并且满足第一条件表达式0.8 <| f1 / f2 | <1.0，f1是第一透镜组的焦距和f2是第二透镜组的焦距。

20. 发明申请

US20060047441A1 Semantic gene organizer 审中-公开
标题翻译：语义基因组织者
公开(公告)号：US20060047441A1
公开(公告)日：2006-03-02
申请号：US11215635
申请日：2005-08-30
申请人： Ramin Homayouni , Michael Berry , Kevin Heinrich , Lai Wei
发明人： Ramin Homayouni , Michael Berry , Kevin Heinrich , Lai Wei
IPC分类号： G06F19/00
CPC分类号： G16B50/00
摘要： A semantic gene classification and annotation system, method and computer program can utilize Latent Semantic Indexing (LSI) to identify conceptually related genes based on textual information in biomedical literature, including MEDLINE citations. In addition, term weights calculated from the usage of the gene terms in and across gene documents can be used to automatically assign gene aliases and extend gene function annotation based upon primary biomedical literature.
摘要翻译：语义基因分类和注释系统，方法和计算机程序可以利用潜在语义索引（LSI）基于生物医学文献中的文本信息来识别与概念相关的基因，包括MEDLINE引文。另外，根据基因文献中和跨基因文献的基因术语的使用计算的术语权重可用于自动分配基因别名并扩展基于主要生物医学文献的基因功能注释。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式