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11. 发明授权

US06846495B2 Compositions having improved delivery of actives 失效
标题翻译：具有改善活性物质递送的组合物
公开(公告)号：US06846495B2
公开(公告)日：2005-01-25
申请号：US09466950
申请日：1999-12-20
申请人： Douglas Joseph Dobrozsi , Jerry William Hayes, II , Kishor Jivanlal Desai , Brian James Robbins
发明人： Douglas Joseph Dobrozsi , Jerry William Hayes, II , Kishor Jivanlal Desai , Brian James Robbins
IPC分类号： A61K9/08 , A61K9/00 , A61K9/107 , A61K9/12 , A61K9/48 , A61K9/64 , A61K9/66 , A61K9/68 , A61K31/00 , A61K31/137 , A61K31/167 , A61K31/435 , A61K31/4353 , A61K31/4402 , A61K31/4439 , A61K31/485 , A61K47/10 , A61K47/34 , A61P11/00 , A61P11/02 , A61P11/10 , A61P11/12 , A61P11/14 , A61K47/00 , A61K9/14
CPC分类号： A61K31/00 , A61K9/0056 , A61K9/006 , A61K9/0095 , A61K31/485 , A61K47/10
摘要： The present invention pertains to compositions having improved delivery of pharmaceutical actives. These compositions comprise pharmaceutical actives in an anhydrous solvent. These compositions may take the form of liquid elixirs placed into the mouth and eventually swallowed, or can be delivered via liquid-filled drops, metered liquid dosing devices, atomizers and liquid-releasing, edible capsules.
摘要翻译：本发明涉及具有改进的药物活性物质递送的组合物。这些组合物在无水溶剂中包含药物活性物质。这些组合物可以采取放置在口中并最终吞咽的液体酏剂的形式，或者可以通过液体填充的滴剂，计量液体剂量装置，雾化器和液体释放的可食用胶囊来递送。

12. 发明授权

US3185226A Shaft sinking apparatus 失效
标题翻译：轴下沉装置
公开(公告)号：US3185226A
公开(公告)日：1965-05-25
申请号：US80000059
申请日：1959-03-17
申请人： JAMES ROBBINS RICHARD
发明人： JAMES ROBBINS RICHARD
IPC分类号： E21D1/03
CPC分类号： E21D1/03

13. 发明授权

US08481726B2 Process for the preparation of sterically hindered nitroxyl ethers 有权
标题翻译：制备空间位阻硝酰基醚的方法
公开(公告)号：US08481726B2
公开(公告)日：2013-07-09
申请号：US12308595
申请日：2007-06-25
申请人： Abdel-Ilah Basbas , Davide Alvisi , Robert Cordova , Michael Peter Difazio , Walter Fischer , Joseph A. Kotrola , Tiziano Nocentini , James Robbins , Kai-Uwe Schöning
发明人： Abdel-Ilah Basbas , Davide Alvisi , Robert Cordova , Michael Peter Difazio , Walter Fischer , Joseph A. Kotrola , Tiziano Nocentini , James Robbins , Kai-Uwe Schöning
IPC分类号： C07D211/94 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07B43/00
CPC分类号： C07D211/94
摘要： The present invention relates to a novel process for the preparation of specific sterically hindered nitroxyl ethers from their corresponding sterically hindered nitroxyl radicals by reacting it with an aldehyde and a hydroperoxide. This nitroxyl ether formation may be carried out from different starting nitroxyl radicals, which are subsequently further reacted to the desired compounds. The compounds prepared by this process are effective as stabilizers for polymers against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers.
摘要翻译：本发明涉及通过使其与醛和氢过氧化物反应从其相应的空间位阻硝酰基制备特定的位阻硝酰基醚的新方法。该硝酰基醚的形成可以从不同的起始硝酰基进行，随后将其进一步与期望的化合物反应。通过该方法制备的化合物作为聚合物的稳定剂是有效的，以防止光，氧和/或热的有害影响，并且作为聚合物的阻燃剂。

14. 发明申请

US20100278957A1 Toggle Drive System For Driving In A Thermoforming Press 有权
标题翻译：切换驱动系统在热成型机中的驱动
公开(公告)号：US20100278957A1
公开(公告)日：2010-11-04
申请号：US12770203
申请日：2010-04-29
申请人： Brian Keeley , Albert Arends , James Martin , James Robbins
发明人： Brian Keeley , Albert Arends , James Martin , James Robbins
IPC分类号： B28B3/00
CPC分类号： B30B1/14 , B29C51/38
摘要： A drive system for double toggle mechanisms used to move upper and lower platens with an electric servo motor-gear box drive shaft driving a crank arm arranged to drive a respective double toggle mechanism in turn connected to the platen. The drive shaft axis is located below the toggle mechanism link pivots and driven in a direction so that the motor acts to assist the double toggle mechanism in lifting the platen, reducing the servo motor peak load. The various components are arranged for symmetrical loading of the pivots concerning the toggle links to increase the evenness of the platen when being raised or lowered.
摘要翻译：用于双肘杆机构的驱动系统，其用于通过电动伺服电动机 - 齿轮箱驱动轴来移动上压板和下压板，所述电动伺服电动机 - 齿轮箱驱动轴驱动曲柄臂，所述曲柄臂被布置成驱动相应的双肘杆机构，所述驱动轴的轴线位于肘节机构连杆的下方，枢轴转动，以使电动机起到帮助双肘杆机构提升压板的作用，从而减小伺服电机的峰值负载。各种部件布置成用于对于与肘节连杆相关的枢轴的对称加载，以在升高或降低时增加压板的均匀度。

15. 发明申请

US20100142567A1 BRANCHED WAVEGUIDE MULTISECTION DBR SEMICONDUCTOR LASER 有权
标题翻译：分支波导多重DBR半导体激光器
公开(公告)号：US20100142567A1
公开(公告)日：2010-06-10
申请号：US12594213
申请日：2008-04-03
申请人： Andrew Ward , Robert Walker , David James Robbins , Douglas Reid , Guy Towlson
发明人： Andrew Ward , Robert Walker , David James Robbins , Douglas Reid , Guy Towlson
IPC分类号： H01S3/1055 , H01S3/10 , H01S5/125 , H01S5/00
CPC分类号： H01S5/06256 , G02B2006/12107 , H01S5/026 , H01S5/10 , H01S5/1003 , H01S5/1092 , H01S5/1209 , H01S5/1212 , H01S5/141 , H01S5/4062 , H01S5/4068 , H01S5/4087
摘要： The present invention concerns tunable distributed Bragg reflector (DBR) semiconductor lasers, in particular a DBR laser with a branched optical waveguide 5 within which a plurality of differently shaped lasing cavities may be formed, and a method of operation of such a laser. The laser may comprise a phase control section (418), gain section (420, 422), a sampled grating DBR (412) giving a comb-line spectrum and two tunable, chirped DBRs (414, 416) for broadband frequency training and a coupling section (410).
摘要翻译：本发明涉及可调谐分布布拉格反射器（DBR）半导体激光器，特别是具有分支光波导5的DBR激光器，其中可以形成多个不同形状的激光腔，以及这种激光器的操作方法。激光器可以包括相位控制部分（418），增益部分（420,422），给出梳状光谱的采样光栅DBR（412）和用于宽带频率训练的两个可调谐啁啾的DBR（414,416），以及耦合部分（410）。

16. 发明申请

US20090298807A1 Compounds 有权
标题翻译：化合物
公开(公告)号：US20090298807A1
公开(公告)日：2009-12-03
申请号：US12365570
申请日：2009-02-04
申请人： Lilian Alcaraz , Andrew Bailey , Richard James Bull , Timothy Johnson , Nicholas David Kindon , Andrew Stuart Lister , Andrew James Robbins , Michael John Stocks , Barry John Teobald
发明人： Lilian Alcaraz , Andrew Bailey , Richard James Bull , Timothy Johnson , Nicholas David Kindon , Andrew Stuart Lister , Andrew James Robbins , Michael John Stocks , Barry John Teobald
IPC分类号： A61K31/5386 , C07D498/10 , A61K31/553 , A61P29/00
CPC分类号： C07D498/10
摘要： The present invention relates to spirocyclic amide derivatives of the formula I, pharmaceutically acceptable salts thereof, a process for their preparation, pharmaceutical compositions containing them, and their use in therapy.
摘要翻译：本发明涉及式I的螺环酰胺衍生物，其药学上可接受的盐，其制备方法，含有它们的药物组合物及其在治疗中的用途。

17. 发明申请

US20080098265A1 System and Method for Embedded Java Memory Footprint Performance Improvement 失效
标题翻译：嵌入式Java存储器脚印性能改进的系统和方法
公开(公告)号：US20080098265A1
公开(公告)日：2008-04-24
申请号：US11967142
申请日：2007-12-29
申请人： Janet Dmitrovich , Philip Langdale , James Robbins , William Tracey
发明人： Janet Dmitrovich , Philip Langdale , James Robbins , William Tracey
IPC分类号： G11C29/04 , G06F9/45
CPC分类号： G06F12/0866 , G06F9/45516 , G06F2212/2022
摘要： A system and method are provided to allow demand loading and discarding of Java executable image (JXE) files. The virtual machine allocates an address space for a requested JXE program. The read-only portion of the JXE file is memory mapped from its nonvolatile location to the allocated memory space using read-only mapping and the read/write section of the JXE file are loaded into memory. When a page of the JXE program is needed, a page fault occurs if the read-only portion has not been loaded into memory. The operating system's page fault handler retrieves the needed page(s) from the nonvolatile storage location based upon the mapping data that resulted from the previously performed memory mapping. Because the read-only section of the JXE file is memory mapped using read-only mapping, the operating system's paging process is free to discard previously loaded memory pages that contain read-only portions of the JXE file.
摘要翻译：提供了一种系统和方法来允许需求加载和丢弃Java可执行映像（JXE）文件。虚拟机为所请求的JXE程序分配一个地址空间。使用只读映射将JXE文件的只读部分从其非易失性位置映射到分配的存储空间，并将JXE文件的读/写部分加载到内存中。当需要JXE程序的页面时，如果只读部分尚未加载到内存中，则会发生页面错误。操作系统的页面错误处理器基于从先前执行的存储器映射产生的映射数据，从非易失性存储位置检索所需的页面。由于JXE文件的只读部分是使用只读映射进行内存映射，因此操作系统的分页过程可以放弃先前加载的包含JXE文件只读部分的内存页面。

18. 发明申请

US20060282216A1 Differential GPS corrections using virtual stations 审中-公开
标题翻译：使用虚拟站进行差分GPS校正
公开(公告)号：US20060282216A1
公开(公告)日：2006-12-14
申请号：US11506300
申请日：2006-08-18
申请人： James Robbins
发明人： James Robbins
IPC分类号： G01C21/00
CPC分类号： G01C15/00 , G01C21/28 , G01S19/07 , G01S19/258 , G01S19/41 , G01S19/43
摘要： Method and apparatus for providing GPS pseudorange correction and carrier phase correction information for navigation or surveying activities over a selected geographic region S of arbitrary size. In a navigation mode, a virtual reference station (VRS), positioned near a selected location L, receives differential GPS (DGPS) correction signals, translates these signals into a selected format, and broadcasts this DGPS information in this format for use by a local user. In a survey mode, the VRS receives corrected GPS information, translates this information into a selected format and broadcasts this translated and corrected GPS information and the VRS location, for use by a mobile station in forming a baseline vector from the GPS mobile station to the VRS location.
摘要翻译：提供GPS伪距校正和用于导航或测量活动的载波相位校正信息的任意大小的选定地理区域S的方法和装置。在导航模式中，位于选定位置L附近的虚拟参考站（VRS）接收差分GPS（DGPS）校正信号，将这些信号转换成选定的格式，并以此格式广播此DGPS信息以供本地使用用户。在测量模式中，VRS接收校正后的GPS信息，将该信息转换成所选择的格式并广播该翻译和校正的GPS信息和VRS位置，供移动台用于从GPS移动台形成基线向量 VRS位置。

19. 发明授权

US07138133B2 Orally administered liquid compositions 有权
标题翻译：口服给药液体组合物
公开(公告)号：US07138133B2
公开(公告)日：2006-11-21
申请号：US09974347
申请日：2001-10-10
申请人： Douglas Joseph Dobrozsi , Jerry William Hayes, II , Francis Joseph David Bealin-Kelly , Jayant Eknath Khanolkar , Benoit Maurice Mullet , Shane Michael DE LA Harpe , Brian James Robbins
发明人： Douglas Joseph Dobrozsi , Jerry William Hayes, II , Francis Joseph David Bealin-Kelly , Jayant Eknath Khanolkar , Benoit Maurice Mullet , Shane Michael DE LA Harpe , Brian James Robbins
IPC分类号： A61K9/10 , A61K47/34
CPC分类号： A61K9/0095 , A61K9/0056 , A61K9/4858 , A61K9/4866 , Y10S514/85 , Y10S514/975
摘要： The present invention is an orally administered liquid pharmaceutical composition that demonstrates excellent physical stability while delivering concentrated levels of the pharmaceutical active(s). Specifically, these compositions for extended periods do not allow the active to precipitate or settle out of solution. Among the advantages of this invention is that the compositions do not require agitation/shaking prior to use as a method to re-suspend or dissolve active drug material to insure even and consistent dosing.
摘要翻译：本发明是口服给药的液体药物组合物，其表现出优异的物理稳定性，同时提供浓度水平的药物活性物质。具体地说，这些组合物长时间不允许活性物沉淀或沉淀出溶液。本发明的优点之一是组合物在使用前不需要搅动/摇动作为重新悬浮或溶解活性药物材料以确保均匀和一致的给药的方法。

20. 发明授权

US07026438B2 Liquid phenolic sulphur-containing antioxidants 有权
标题翻译：液态酚类含硫抗氧化剂
公开(公告)号：US07026438B2
公开(公告)日：2006-04-11
申请号：US10723744
申请日：2003-11-26
申请人： Hugo Camenzind , Paul Dubs , Roger Martin , David Eliezer Chasan , Gunnar Demme , James Robbins
发明人： Hugo Camenzind , Paul Dubs , Roger Martin , David Eliezer Chasan , Gunnar Demme , James Robbins
IPC分类号： C08G63/688 , C08G75/00
CPC分类号： C10M159/12 , C07C323/12 , C10M135/26 , C10M2205/0285 , C10M2207/021 , C10M2207/281 , C10M2207/289 , C10M2215/064 , C10M2215/223 , C10M2219/084 , C10M2219/085 , C10N2230/04 , C10N2230/10 , C10N2240/10 , C10N2240/102 , C10N2240/104
摘要： The invention relates to liquid sulphur-containing antioxidants and to compositions comprising them. The novel lubricant compositions comprise the reaction product of a selected group of 5-tert-butyl-4-hydroxy-3-methyl(or tert-butyl)phenyl substituted carboxylic acid esters with thiodiethylene glycol and a mono-hydroxy alcohol with a carbon chain length higher than 4 C-atoms. The novel lubricant compositions are highly resistant to oxidative degradation and are capable of reducing the negative effects of deposits, such as black sludge, in motor combustion engines, particularly spark ignition internal combustion engines.
摘要翻译：本发明涉及液体含硫抗氧化剂及其组合物。新型润滑剂组合物包含5-选择的5-叔丁基-4-羟基-3-甲基（或叔丁基）苯基取代的羧酸酯与硫代二乙二醇和单羟基醇与碳链的反应产物长度高于4个C原子。新型润滑剂组合物对氧化降解具有高度抗性，并且能够减少马达内燃机，特别是火花点火内燃机中的沉积物如黑色污泥的负面影响。

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