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11. 发明授权

US06884428B2 Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration 有权
标题翻译：使用增强的泡沫植入物，增强软组织修复和再生的完整性
公开(公告)号：US06884428B2
公开(公告)日：2005-04-26
申请号：US10320751
申请日：2002-12-16
申请人： Francois Binette , Steven M. Bowman , Izi Bruker , Julia Hwang , Mora Carolynne Melican , Alireza Rezania
发明人： Francois Binette , Steven M. Bowman , Izi Bruker , Julia Hwang , Mora Carolynne Melican , Alireza Rezania
IPC分类号： A61B17/56 , A61F2/00 , A61F2/02 , A61F2/08 , A61F2/28 , A61F2/30 , A61F2/38 , A61L27/44 , A61L27/46 , A61L27/48 , A61L27/56 , A61L27/58 , A61L31/12 , A61L31/14 , A61F13/00 , A61F9/14
CPC分类号： A61L27/446 , A61F2/0063 , A61F2/08 , A61F2/30756 , A61F2/3872 , A61F2002/2817 , A61F2002/30004 , A61F2002/30011 , A61F2002/30062 , A61F2002/30677 , A61F2002/30766 , A61F2002/3092 , A61F2002/30957 , A61F2002/30971 , A61F2210/0004 , A61F2240/001 , A61F2240/004 , A61F2250/0014 , A61F2250/0023 , A61F2250/0067 , A61L27/44 , A61L27/46 , A61L27/48 , A61L27/56 , A61L27/58 , A61L31/127 , A61L31/128 , A61L31/129 , A61L31/146 , A61L31/148
摘要： A biocompatible tissue repair stimulating implant or “scaffold” device is used to repair tissue injuries, particularly injuries to ligaments, tendons, and nerves. Such implants are especially useful in methods that involve surgical procedures to repair injuries to ligament, tendon, and nerve tissue in the hand and foot. The repair procedures may be conducted with implants that contain a biological component that assists in healing or tissue repair.
摘要翻译：使用生物相容性组织修复刺激植入物或“支架”装置来修复组织损伤，特别是对韧带，腱和神经的损伤。这种植入物在涉及手术和手足以修复韧带，腱和神经组织损伤的手术方法中特别有用。修复程序可以用包含有助于愈合或组织修复的生物成分的植入物进行。

12. 发明授权

US06852330B2 Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration 有权
标题翻译：增强的泡沫植入物具有增强的软组织修复和再生的完整性
公开(公告)号：US06852330B2
公开(公告)日：2005-02-08
申请号：US09747488
申请日：2000-12-21
申请人： Steven M. Bowman , Izi Bruker , Alireza Rezania
发明人： Steven M. Bowman , Izi Bruker , Alireza Rezania
IPC分类号： A61L27/44 , A61L27/48 , A61L27/56 , A61K2/02 , A61K9/14 , B32B3/12
CPC分类号： A61L27/48 , A61L27/44 , A61L27/56 , Y10T428/24149
摘要： A biocompatible tissue repair stimulating implant or “scaffold” device, and methods for making and using such a device, are provided. The implant includes one or more layers of a bioabsorbable polymeric foam having pores with an open cell pore structure. A reinforcement component is also present within the implant to contribute enhanced mechanical and handling properties. The implant houses a biological component that may be released to tissue adjacent the location in which the implant is implanted to faciliate and/or expedite the healing of tissue. This biological component resides primarily within the foam component of the implant, being incorporated within pores formed within the foam.
摘要翻译：提供了生物相容性组织修复刺激植入物或“支架”装置，以及制造和使用这种装置的方法。植入物包括一层或多层具有开孔细孔结构的孔的生物可吸收聚合物泡沫。植入物内还存在增强组分，以增强机械和操作性能。植入物容纳可以被释放到植入物植入位置附近的组织以促进和/或加速组织愈合的生物成分。该生物成分主要存在于植入物的泡沫组分内，并被结合在泡沫内形成的孔中。

13. 发明授权

US06402766B2 Graft fixation device combination 有权
标题翻译：移植固定装置组合
公开(公告)号：US06402766B2
公开(公告)日：2002-06-11
申请号：US09793036
申请日：2001-02-26
申请人： Steven M. Bowman , Izi Bruker
发明人： Steven M. Bowman , Izi Bruker
IPC分类号： A61B1708
CPC分类号： A61B17/0401 , A61B17/00234 , A61B17/06 , A61B17/0642 , A61B17/068 , A61B17/92 , A61B2017/00004 , A61B2017/00243 , A61B2017/00783 , A61B2017/0406 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0419 , A61B2017/0427 , A61B2017/0445 , A61B2017/06057 , A61B2017/0608 , A61B2017/0646 , A61B2017/0647 , A61F2/0063 , A61F2/0811 , A61F2/2846 , Y10S606/907 , Y10S606/908 , Y10S606/91 , Y10S606/916
摘要： A graft fixation device combination. The device is useful for affixing a tissue graft to a bone or other body surface. The combination has a fixation device having two implantation members connected by a connecting member. The connecting member has at least one lateral wing member extending therefrom. The implantation members have longitudinal passageways therethrough. The combination also has an insertion member in engagement with the distal end of each implantation member.
摘要翻译：移植物固定装置组合。该装置可用于将组织移植物固定到骨骼或其他身体表面。该组合具有固定装置，其具有通过连接构件连接的两个植入构件。连接构件具有从其延伸的至少一个侧翼构件。植入构件具有穿过其的纵向通道。该组合还具有与每个植入构件的远端接合的插入构件。

14. 发明授权

US5358510A Two part surgical fastener 失效
标题翻译：两部分手术紧固件
公开(公告)号：US5358510A
公开(公告)日：1994-10-25
申请号：US009157
申请日：1993-01-26
申请人： Brian H. Luscombe , Izi Bruker , Leslie Hamilton , Thu A. Le
发明人： Brian H. Luscombe , Izi Bruker , Leslie Hamilton , Thu A. Le
IPC分类号： A61B17/08 , A61B17/064 , A61B17/00
CPC分类号： A61B17/0643 , A61B2017/0641
摘要： A method of tissue compression is disclosed herein where the device to cause such compression is composed of a fastener bar and receiver. The device has the capability to self-adjust to tissues of varying thicknesses to cause hemostasis. This tissue gap variability allows for compression of regions of tissue where thick and thin tissue are both present. This variability also enables the same device to be used on a wide variety of tissues of different thicknesses. The tissue fastener bar of this invention contains a series of cut-out portions which distribute the compressive forces along the device in an alternating, staggered manner. The receiver is of a generally U-shaped configuration with the fastener bar being contained at least partially within the U-shape. Compression occurs between the side walls of the receiver and the fastener bar and variability in gap is accomplished by flexure of the side walls of the receiver. Varying side wall flexure is enhanced by cut-out portions in the receiver which allow each segment to flex somewhat independently. A number of options also exist for configuration of the fastener bar and/or receiver with the same basic method of compression being unchanged.
摘要翻译：本文公开了一种组织压缩的方法，其中引起这种压缩的装置由紧固杆和接收器组成。该装置能够对不同厚度的组织进行自我调节，从而导致止血。这种组织间隙变异性允许压缩组织的厚度和薄组织都存在的区域。这种变化性也使得相同的装置能够用于各种不同厚度的组织上。本发明的组织拉链包含一系列切割部分，其以交替的交错方式沿着装置分布压缩力。接收器具有大致U形的构造，其中紧固杆至少部分地包含在U形内。在接收器的侧壁和拉链条之间发生压缩，并且通过接收器侧壁的挠曲来实现间隙的变化。不同的侧壁弯曲通过接收器中的切口部分增强，这允许每个片段有些独立地弯曲。还存在用于配置具有相同基本压缩方式的拉链和/或接收器的多种选择。

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