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11. 发明授权

US06759909B2 RF energy dispersal in systems consisting of aggregated computing elements as subsystems 有权
标题翻译： RF能量在由聚合计算元素组成的系统中作为子系统
公开(公告)号：US06759909B2
公开(公告)日：2004-07-06
申请号：US10064217
申请日：2002-06-21
申请人： James Edward Hughes , George Courtney Long, Jr. , Rudolf Eugene Rehquate
发明人： James Edward Hughes , George Courtney Long, Jr. , Rudolf Eugene Rehquate
IPC分类号： H03L707
CPC分类号： G06F1/08
摘要： A cluster of processing systems wherein each system is set to operate at a unique operating frequency. Each unique frequency is set to differ from each other by at least a predetermined frequency differential or bandwidth. When clustered, the radiated emissions will not add. Rather, the RF energy is distributed over the predetermined frequency bandwidth and in so doing achieve a reduction of measured RF energy at any singular frequency. By using RF energy dispersal in aggregate systems, the need for special or additional RF shielding is precluded. Current design and manufacturing techniques can continue to be used. Thus, reducing the overall cost of implementing aggregated systems.
摘要翻译：一组处理系统，其中每个系统被设置为以独特的工作频率运行。每个唯一频率被设置为彼此不同至少预定的频率差分或带宽。集群时，辐射的排放量不会增加。相反，RF能量分布在预定的频率带宽上，从而实现在任何奇异频率下测量的RF能量的减少。通过在聚集体系中使用RF能量分散，不需要特殊的或附加的RF屏蔽。目前的设计和制造技术可以继续使用。因此，降低实施汇总系统的总体成本。

12. 发明授权

US06377218B1 Device for providing an antenna, a receptacle, and a physical connector on a type II PCMCIA card 失效
标题翻译：用于在II型PCMCIA卡上提供天线，插座和物理连接器的装置
公开(公告)号：US06377218B1
公开(公告)日：2002-04-23
申请号：US09684286
申请日：2000-10-04
申请人： Jon A. Nelson , Edward Hughes
发明人： Jon A. Nelson , Edward Hughes
IPC分类号： H01Q124
CPC分类号： H01Q1/2275 , H01Q1/084 , H01Q1/20 , H01Q1/22
摘要： A peripheral component providing multiple types of interfaces. In one embodiment, the peripheral component comprises a housing with logical circuitry within. A receptacle is electrically connected to the logical circuitry. The receptacle may be operable to receive an RJ-11 plug and/or an RJ-45 plug. A wireline interface, for example, a 15-pin connector, is also electrically connected to the logical circuitry. Furthermore, a resilient antenna is electrically connected to the logical circuitry. The antenna is operable to conform to fit inside the housing, and when extracted, the antenna is operable to return substantially to a pre-determined shape, wherein reception and transmission of a wireless signal are optimized. In one embodiment, the logical circuitry of the peripheral component comprises a wireless device, for example, a Bluetooth™ device. In another embodiment, the peripheral component is a type II PCMCIA card. In still another embodiment, the receptacle is an X-Jack™. In still another embodiment, the wireline interface is adapted to receive a 15-pin connector.
摘要翻译：提供多种类型接口的外设组件。在一个实施例中，外围组件包括具有逻辑电路的壳体。插座与逻辑电路电连接。插座可操作以接收RJ-11插头和/或RJ-45插头。电缆接口，例如15针连接器，也电连接到逻辑电路。此外，弹性天线电连接到逻辑电路。天线可操作地适合于配合在壳体内部，并且当提取时，天线可操作以基本上返回到预定形状，其中无线信号的接收和发送被优化。在一个实施例中，外围组件的逻辑电路包括无线设备，例如Bluetooth TM设备。在另一个实施例中，外围组件是II型PCMCIA卡。在另一个实施例中，插座是X-Jack TM。在另一个实施例中，电缆接口适于接收15针连接器。

13. 发明授权

US3517383A Turn signal monitor 失效
标题翻译：转向信号监控
公开(公告)号：US3517383A
公开(公告)日：1970-06-23
申请号：US3517383D
申请日：1967-03-20
申请人： KENNETH EDWARD HUGHES
发明人： HUGHES KENNETH EDWARD
IPC分类号： B60Q1/38
CPC分类号： B60Q1/38

14. 发明授权

US3033322A Braking and retarding apparatus 失效
标题翻译：制动和减速装置
公开(公告)号：US3033322A
公开(公告)日：1962-05-08
申请号：US68727157
申请日：1957-09-30
申请人： EDWARD HUGHES GEORGE
发明人： EDWARD HUGHES GEORGE
IPC分类号： F16D57/06
CPC分类号： F16D57/06

15. 植物专利

USPP32414P2 Sedum plant named ‘Gold Form’ 有权
公开(公告)号：USPP32414P2
公开(公告)日：2020-10-27
申请号：US16602290
申请日：2019-09-06
申请人： Jared Edward Hughes
发明人： Jared Edward Hughes
IPC分类号： A01H5/02 , A01H6/32
摘要： A new and distinct cultivar of Sedum plant named ‘Gold Form’, characterized by its compact, dense and bushy growth habit; initially upright to trailing to weeping and decumbent plant habit; freely basally and laterally branching habit; yellow green-colored leaves; and good garden performance and winter hardiness.

16. 发明申请

US20140142145A1 COMBINATIONS COMPRISING A DIPEPTIDYLPEPTIDASE - IV INHIBITOR 审中-公开
标题翻译：包含脯氨酸 - Ⅳ抑制剂的组合
公开(公告)号：US20140142145A1
公开(公告)日：2014-05-22
申请号：US14075556
申请日：2013-11-08
申请人： Bork Balkan , Thomas Edward Hughes , David Grenville Holmes , Edwin Bemard Villhauer
发明人： Bork Balkan , Thomas Edward Hughes , David Grenville Holmes , Edwin Bemard Villhauer
IPC分类号： A61K31/40 , A61K45/06 , A61K31/422 , A61K31/4439 , A61K31/427 , A61K31/421
CPC分类号： A61K31/40 , A61K31/421 , A61K31/422 , A61K31/427 , A61K31/4439 , A61K45/06 , A61K2300/00
摘要： The present invention is directed to a combination comprising a dipeptidylpeptidase-IV (DPP-IV) inhibitor in free or pharmaceutically acceptable form, and at least one further antidiabetic compound or the pharmaceutically acceptable salt of such a compound, and optionally at least one pharmaceutically acceptable carrier, for simultaneous, separate or sequential use in the prevention, delay of progression or treatment of conditions mediated by DPP-IV, such as impaired glucose tolerance, conditions of impaired fasting plasma glucose, metabolic acidosis, ketosis, arthritis, obesity and osteoporosis, and preferably diabetes, especially type 2 diabetes mellitus.
摘要翻译：本发明涉及包含游离或药学上可接受的形式的二肽基肽酶-IV（DPP-IV）抑制剂和至少一种其它抗糖尿病化合物或其药学上可接受的盐，以及任选的至少一种药学上可接受的组合物载体，用于在DPP-IV介导的病症的预防，延缓进展或治疗中的同时，分开或顺序使用，例如葡萄糖耐量降低，空腹血浆葡萄糖受损的病症，代谢性酸中毒，酮症，关节炎，肥胖症和骨质疏松症，优选糖尿病，特别是2型糖尿病。

17. 发明申请

US20120058263A1 HIGH PERFORMANCE NANO-METAL HYBRID FISHING TACKLE 审中-公开
标题翻译：高性能纳米金属杂交渔具
公开(公告)号：US20120058263A1
公开(公告)日：2012-03-08
申请号：US13195644
申请日：2011-08-01
申请人： David Pierick , Andy Brutlag , William F. Davidson, III , Edward Hughes
发明人： David Pierick , Andy Brutlag , William F. Davidson, III , Edward Hughes
IPC分类号： B05D1/12
CPC分类号： B05D1/12 , A01K87/00 , A01K89/01121 , A01K89/0192
摘要： Fishing tackle is coated with nanostructured material to modify and improve the performance. The fishing tackle includes a fishing rod which is coated adjacent a first end section, in a middle section, adjacent a second end section, or over an entire surface to improve the action, power or any performance characteristic and/or decrease weight, The fishing tackle includes a fishing reel which is coated in whole or part with a nanostructured material to improve strength, corrosion resistance or performance and/or decrease weight. The fishing tackle includes a fishing rod guide which is coated with a nanostructured material to improve performance and/or decrease weight. The area of coverage and thickness of the material coated on each component of the fishing tackle can be changed, as stipulated by design criterion.
摘要翻译：钓具用纳米结构材料涂层以改善和提高性能。钓鱼钩包括一个在第一端部附近涂覆的钓鱼竿，中间部分邻近第二端部或整个表面，以改善动作，动力或任何性能特征和/或减轻重量。钓鱼滑车包括全部或部分用纳米结构材料涂覆的钓鱼卷轴，以提高强度，耐腐蚀性或性能和/或减轻重量。钓鱼钩包括一个钓鱼杆导向器，该导向器涂覆有纳米结构材料以改善性能和/或减轻重量。按照设计标准，可以改变涂覆在钓具各部件上的材料的覆盖面积和厚度。

18. 发明申请

US20090017015A1 Dpp-iv inhibitors for treating neurodegeneration and cognitive disorders 审中-公开
标题翻译：用于治疗神经变性和认知障碍的Dpp-iv抑制剂
公开(公告)号：US20090017015A1
公开(公告)日：2009-01-15
申请号：US10589690
申请日：2005-02-18
申请人： Thomas Edward Hughes
发明人： Thomas Edward Hughes
IPC分类号： A61K39/395 , A61K31/4439 , A61K31/40 , A61K31/426 , A61K31/403 , A61K31/445 , A61K31/473 , A61K31/55 , A61K31/66 , A61K31/439 , A61P25/00 , A61K38/13 , A61K31/4164 , A61K31/433 , A61K31/47 , A61K31/505 , A61K31/5415 , A61K31/4985 , A61K33/24
CPC分类号： A61K31/00 , A61K31/40 , A61K31/4196 , A61K31/4439 , A61K31/472
摘要： The invention relates to the use of a Dipeptidyl peptidase IV inhibitor (DPP-IV inhibitor) or a pharmaceutically acceptable salt thereof for the prevention, delay of progression or the treatment of neurodegenerative disorders, cognitive disorders and for improving memory (both short term and long term) and learning ability.
摘要翻译：本发明涉及二肽基肽酶IV抑制剂（DPP-IV抑制剂）或其药学上可接受的盐在预防，延缓进展或治疗神经变性疾病，认知障碍和改善记忆（短期和长期期限）和学习能力。

19. 发明申请

US20080300171A1 Use of Dpp-IV Inhibitor to Reduce Hypoglycemic Events 失效
标题翻译：使用Dpp-IV抑制剂降低低血糖事件
公开(公告)号：US20080300171A1
公开(公告)日：2008-12-04
申请号：US12067314
申请日：2006-09-18
申请人： Bork Balkan , David Grenville Holmes , Thomas Edward Hughes , Edwin Bernard Villhauer
发明人： Bork Balkan , David Grenville Holmes , Thomas Edward Hughes , Edwin Bernard Villhauer
IPC分类号： A61K38/28 , A61K31/40 , A61P3/10
CPC分类号： A61K45/06 , A61K31/155 , A61K31/64 , A61K38/28 , A61K2300/00
摘要： The invention relates to a method to reduce the hypoglycemic events, especially sever hypoglycemic events resulting from insulin treatment, wherein the patient is treated with a Dipeptidyl peptidase IV inhibitor (DPP-IV inhibitor) or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明涉及一种减少低血糖事件的方法，特别是由胰岛素治疗引起的切断的低血糖事件，其中患者用二肽基肽酶IV抑制剂（DPP-IV抑制剂）或其药学上可接受的盐治疗。

20. 发明申请

US20080221200A1 Combination of Organic Compounds 审中-公开
标题翻译：有机化合物的组合
公开(公告)号：US20080221200A1
公开(公告)日：2008-09-11
申请号：US12067822
申请日：2006-09-28
申请人： Malcolm Allison , Bryan Burkey , Thomas Edward Hughes , Daniel Matthew Kemp
发明人： Malcolm Allison , Bryan Burkey , Thomas Edward Hughes , Daniel Matthew Kemp
IPC分类号： A61K31/402 , A61P3/10 , A61P17/06 , A61P37/06
CPC分类号： A61K45/06 , A61K31/40 , A61K2300/00
摘要： The present invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, comprising of a DPP IV inhibitor or a pharmaceutically acceptable salt thereof and comprising at least one immunosuppressive or immunomodulator agent, or a pharmaceutically acceptable salt thereof.The present invention furthermore relates to the use of such a combination for the prevention, delay of progression or treatment of diseases and disorders that may be inhibited by DPP IV inhibition, for the prevention, delay of progression or treatment of autoimmune diseases, and the disorders associated therewith, or for the prevention, delay of progression or treatment of graft rejection.
摘要翻译：本发明涉及分别包含DPP IV抑制剂或其药学上可接受的盐并且包含至少一种免疫抑制剂或免疫调节剂或其药学上可接受的盐的组合制剂或药物组合物的组合。本发明还涉及这种组合用于预防，延缓进展或治疗DPP IV抑制可能被抑制的疾病和病症，用于预防，延缓进展或治疗自身免疫性疾病以及所述疾病或用于预防，延缓进展或治疗移植排斥反应。

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