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11. 发明申请

US20060000979A1 Device and method for digitizing pet radiation events 有权
标题翻译：宠物辐射事件数字化的装置和方法
公开(公告)号：US20060000979A1
公开(公告)日：2006-01-05
申请号：US11097153
申请日：2005-04-04
申请人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
发明人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
IPC分类号： G01T1/164
CPC分类号： G01T1/17 , A61B6/037 , G01T1/1647 , G01T1/2985
摘要： A device and method used in the high resolution Positron Emission Tomography (PET) systems for digitizing radiation events for a scintillation camera and a data acquisition system. The device comprises a scintillation digitizer, including a plurality of comparators and amplifiers, two ADCs, and an analyzer for resolving the digital values of radiation events. The method comprises comparing a plurality of analog electric pulses generated upon radiation event detections with a reference voltage corresponding to an energy level of interest, amplifying all of the signals with two groups of coefficients, summing the two groups of amplified signals, digitizing the summed signals, and analyzing the digitized sums to determine digital values corresponding to a plurality of the radiation events.
摘要翻译：用于数字化用于闪烁照相机和数据采集系统的辐射事件的高分辨率正电子发射断层扫描（PET）系统中的装置和方法。该装置包括闪烁数字转换器，包括多个比较器和放大器，两个ADC和用于分辨辐射事件的数字值的分析器。该方法包括将辐射事件检测所产生的多个模拟电脉冲与对应于感兴趣能级的参考电压进行比较，用两组系数放大所有信号，对两组放大信号求和，对相加的信号进行数字化并且分析数字化和以确定对应于多个辐射事件的数字值。

12. 发明申请

US20110044546A1 Image Reconstruction From Limited or Incomplete Data 有权
标题翻译：数据有限或不完整的图像重建
公开(公告)号：US20110044546A1
公开(公告)日：2011-02-24
申请号：US12223946
申请日：2007-02-12
申请人： Xiaochuan M. Pan , Emil Sidky , Chien-min Kao
发明人： Xiaochuan M. Pan , Emil Sidky , Chien-min Kao
IPC分类号： G06K9/46
CPC分类号： G06T11/006 , G06T11/005 , G06T2211/424 , G06T2211/432 , G06T2211/436
摘要： A system and method are provided for reconstructing images from limited or incomplete data, such as few view data or limited angle data or truncated data (including exterior and interior data) generated from divergent beams. In one aspect of the invention, the method and apparatus iteratively constrains the variation of an estimated image in order to reconstruct the image. As one example, a divergent beam maybe used to generate data (“actual data”). As discussed above, the actual data may be less than sufficient to exactly reconstruct the image by conventional techniques, such as FBP. In order to reconstruct an image, a first estimated image may be generated. Estimated data may be generated from the first estimated image, and compared with the actual data. The comparison of the estimated data with the actual data may include determining a difference between the estimated and actual data. The comparison may then be used to generate a new estimated image. For example, the first estimated image may be combined with an image generated from the difference data to generate a new estimated image. In order to generate the image for the next iteration, the variation of the new estimated image may be constrained. For example, the variation of the new estimated image may be at least partly constrained in order to lessen or reducing the total variation of the image.
摘要翻译：提供了一种系统和方法，用于从有限或不完整的数据重建图像，例如由发散光束产生的少量视图数据或有限角度数据或截断数据（包括外部和内部数据）。在本发明的一个方面，该方法和装置迭代地约束了估计图像的变化，以便重建图像。作为一个示例，可以使用发散光束来生成数据（“实际数据”）。如上所述，实际数据可能不足以通过诸如FBP的常规技术精确地重建图像。为了重建图像，可以生成第一估计图像。可以从第一估计图像生成估计数据，并与实际数据进行比较。估计数据与实际数据的比较可以包括确定估计数据和实际数据之间的差异。然后可以使用比较来生成新的估计图像。例如，第一估计图像可以与从差数据生成的图像组合以生成新的估计图像。为了生成用于下一次迭代的图像，新估计图像的变化可能受到约束。例如，新估计图像的变化可以至少部分地被限制，以便减少或减少图像的总变化。

13. 发明授权

US07342232B2 Device and method for digitizing pet radiation events 有权
标题翻译：宠物辐射事件数字化的装置和方法
公开(公告)号：US07342232B2
公开(公告)日：2008-03-11
申请号：US11097153
申请日：2005-04-04
申请人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
发明人： Qingguo Xie , Chien-Min Kao , Zekai Hsiau , Chin-Tu Chen
IPC分类号： G01T1/164
CPC分类号： G01T1/17 , A61B6/037 , G01T1/1647 , G01T1/2985
摘要： A device and method used in the high resolution Positron Emission Tomography (PET) systems for digitizing radiation events for a scintillation camera and a data acquisition system. The device comprises a scintillation digitizer, including a plurality of comparators and amplifiers, two ADCs, and an analyzer for resolving the digital values of radiation events. The method comprises comparing a plurality of analog electric pulses generated upon radiation event detections with a reference voltage corresponding to an energy level of interest, amplifying all of the signals with two groups of coefficients, summing the two groups of amplified signals, digitizing the summed signals, and analyzing the digitized sums to determine digital values corresponding to a plurality of the radiation events.
摘要翻译：用于数字化用于闪烁照相机和数据采集系统的辐射事件的高分辨率正电子发射断层扫描（PET）系统中的装置和方法。该装置包括闪烁数字转换器，包括多个比较器和放大器，两个ADC和用于分辨辐射事件的数字值的分析器。该方法包括将辐射事件检测所产生的多个模拟电脉冲与对应于感兴趣能级的参考电压进行比较，用两组系数放大所有信号，对两组放大信号求和，对相加的信号进行数字化并且分析数字化和以确定对应于多个辐射事件的数字值。

14. 发明授权

US07245755B1 Algorithm for image reconstruction and image noise analysis in computed tomography 失效
标题翻译：计算机断层扫描中的图像重建和图像噪声分析算法
公开(公告)号：US07245755B1
公开(公告)日：2007-07-17
申请号：US10616671
申请日：2003-07-10
申请人： Xiaochuan Pan , Lifeng Yu , Chien-Min Kao
发明人： Xiaochuan Pan , Lifeng Yu , Chien-Min Kao
IPC分类号： G06K9/00
CPC分类号： G06T11/005 , A61B6/027 , A61B6/583
摘要： A method and apparatus are provided for reconstructing a tomographic image from fan-beam or cone-beam data. The method includes the steps of collecting fan-beam or cone-beam data over an image space, converting the fan-beam or cone-beam data to parallel-beam data with respect to a rotation angle within the image space, performing a shift variant filtration of the parallel-beam data within the image space and converting the processed data to images through backprojection or other means.
摘要翻译：提供了一种用于从扇形束或锥形束数据重建断层图像的方法和装置。该方法包括以下步骤：在图像空间上收集扇形束或锥形束数据，将扇形束或锥形束数据相对于图像空间内的旋转角度转换为平行光束数据，执行偏移变化过滤图像空间内的平行光束数据，并通过反投影或其他方式将处理后的数据转换为图像。

15. 发明申请

US20110170757A1 Imaging System 有权
标题翻译：成像系统
公开(公告)号：US20110170757A1
公开(公告)日：2011-07-14
申请号：US12930856
申请日：2011-01-19
申请人： Xiaochuan Pan , Yu Zou , Lifeng Yu , Chien-Min Kao , Martin King , Maryellen Giger , Dan Xia , Howard Halpern , Charles Pelizzari , Emil Y. Sidky , Seungryong Cho
发明人： Xiaochuan Pan , Yu Zou , Lifeng Yu , Chien-Min Kao , Martin King , Maryellen Giger , Dan Xia , Howard Halpern , Charles Pelizzari , Emil Y. Sidky , Seungryong Cho
IPC分类号： G06K9/00
CPC分类号： A61B6/5288 , A61B6/027 , A61B6/032 , A61B6/037 , A61B6/484 , A61B6/508 , A61B6/5264 , A61B6/583 , A61B6/587
摘要： A method and apparatus for reconstruction of a region of interest for an object is provided. The reconstruction of the object may be based on chords which may fill a part, all, or more than all of the region of interest. Using chords for reconstruction may allow for reducing data acquired and/or processing for reconstructing a substantially exact image of the ROI. Moreover, various methodologies may be used in reconstructing the image, such as backprojection-filtration, and modified filtration backprojection.
摘要翻译：提供了一种用于重建对象的感兴趣区域的方法和装置。对象的重建可以基于可以填充所有感兴趣区域的全部或全部的和弦。使用和弦进行重建可以允许减少获得的数据和/或用于重建ROI的基本上精确的图像的处理。此外，各种方法可用于重建图像，例如反投影过滤和修改过滤反投影。

16. 发明申请

US20090175562A1 Imaging system 审中-公开
标题翻译：成像系统
公开(公告)号：US20090175562A1
公开(公告)日：2009-07-09
申请号：US12288480
申请日：2008-10-21
申请人： Xiaochuan Pan , Yu Zou , Lifeng Yu , Chien-Min Kao , Martin King , Maryellen Giger , Dan Xia , Howard Halpern , Charles Pelizzari , Emil Y. Sidky , Seungryong Cho
发明人： Xiaochuan Pan , Yu Zou , Lifeng Yu , Chien-Min Kao , Martin King , Maryellen Giger , Dan Xia , Howard Halpern , Charles Pelizzari , Emil Y. Sidky , Seungryong Cho
IPC分类号： G06K9/20
CPC分类号： A61B6/5288 , A61B6/027 , A61B6/032 , A61B6/037 , A61B6/484 , A61B6/508 , A61B6/5264 , A61B6/583 , A61B6/587
摘要： A method and apparatus for reconstruction of a region of interest for an object is provided. The reconstruction of the object may be based on chords which may fill a part, all, or more than all of the region of interest. Using chords for reconstruction may allow for reducing data acquired and/or processing for reconstructing a substantially exact image of the ROI. Moreover, various methodologies may be used in reconstructing the image, such as backprojection-filtration, and modified filtration backprojection.
摘要翻译：提供了一种用于重建对象的感兴趣区域的方法和装置。对象的重建可以基于可以填充所有感兴趣区域的全部或全部的和弦。使用和弦进行重建可以允许减少获得的数据和/或用于重建ROI的基本上精确的图像的处理。此外，各种方法可用于重建图像，例如反投影过滤和修改过滤反投影。

17. 发明授权

US07444011B2 Imaging system performing substantially exact reconstruction and using non-traditional trajectories 有权
标题翻译：成像系统执行基本精确的重建和使用非传统轨迹
公开(公告)号：US07444011B2
公开(公告)日：2008-10-28
申请号：US11410594
申请日：2006-04-24
申请人： Xiaochuan Pan , Yu Zou , Lifeng Yu , Chien-Min Kao , Martin King , Maryellen Giger , Dan Xia , Howard Halpern , Charles Pelizzari , Emil Y. Sidky , Seungryong Cho
发明人： Xiaochuan Pan , Yu Zou , Lifeng Yu , Chien-Min Kao , Martin King , Maryellen Giger , Dan Xia , Howard Halpern , Charles Pelizzari , Emil Y. Sidky , Seungryong Cho
IPC分类号： G06K9/46
CPC分类号： G06T11/006 , A61B6/027 , A61B6/502 , A61B6/5288 , G06T2211/432 , G06T2211/436
摘要： A method and apparatus for reconstruction of a region of interest (ROI) for an object using an imaging system is provided. The imaging system may substantially exactly reconstruct the ROI with a straight line trajectory. In the straight line trajectory, the ROI is not bounded or encircled by the actual trajectory of the source (e.g., no chords that are composed from two points on the source trajectory intersect or fill the ROI to be imaged). However, the ROI may be substantially reconstructed by using “virtual” chords to reconstruct the ROI. The virtual chords are such that no point on the trajectory is included in the virtual chord (such as one that is parallel to the straight line trajectory). These virtual chords may intersect and fill the ROI, thus enabling substantially exact reconstruction. Further, in reconstructing the image, the straight line trajectory may be assumed to be infinite in length.
摘要翻译：提供了一种用于使用成像系统重建用于对象的感兴趣区域（ROI）的方法和装置。成像系统可以用直线轨迹基本上精确地重建ROI。在直线轨迹中，ROI不受源的实际轨迹的限制或环绕（例如，由源轨迹上的两个点组成的和弦不相交或填充要被成像的ROI）。然而，可以通过使用“虚拟”和弦来重建ROI来实质地重建ROI。虚拟和弦使虚拟和弦中不包含轨迹上的点（例如平行于直线轨迹的点）。这些虚拟和弦可以相交并填充ROI，从而实现基本精确的重建。此外，在重建图像时，可以认为直线轨迹的长度是无限大的。

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