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11. 发明申请

US20190099570A1 PATIENT INTERFACE WITH INTEGRATED JET PUMP 审中-公开
公开(公告)号：US20190099570A1
公开(公告)日：2019-04-04
申请号：US15724169
申请日：2017-10-03
申请人： Breathe Technologies, Inc.
发明人： Enrico Brambilla , Samir Ahmad , Larry Mastrovich , Gary Berman , David Mastrovich
IPC分类号： A61M16/00 , A61M16/06 , A61M16/08 , A61M16/10
CPC分类号： A61M16/0096 , A61M16/0063 , A61M16/0666 , A61M16/0672 , A61M16/0816 , A61M16/0833 , A61M16/0858 , A61M16/0875 , A61M16/101 , A61M16/12 , A61M16/127 , A61M2016/0027 , A61M2202/0208
摘要： A patient circuit of a ventilation system, such as a non-invasive open ventilation system, wherein the patient circuit comprises a nasal pillows style patient interface that incorporates at least one “Venturi effect” jet pump proximal to the patient. The patient circuit further comprises a pair of uniquely configured 3-way connectors which, in cooperation with several uniquely configured tri-lumen tubing segments, facilitate the cooperative engagement of the patient interface to a ventilator of the ventilation system.

12. 发明授权

US10183135B2 Zero pressure start continuous positive airway pressure therapy 有权
公开(公告)号：US10183135B2
公开(公告)日：2019-01-22
申请号：US14482445
申请日：2014-09-10
申请人： BREATHE TECHNOLOGIES, INC.
发明人： Samir S. Ahmad , Leonardo Alberto Baloa-Welzien
IPC分类号： A61M16/00 , A61M16/06 , A61M16/10
摘要： A respiratory assistance device is disclosed. There is a patient interface for coupling to a patient respiratory passageway, and a selectively regulated therapeutic gas flow source in pneumatic communication with the patient over the patient interface. A controller is connected to the therapeutic gas flow source and is receptive to inputs of a prescription pressure level and an initial delay duration. After the patient dons the patient interface, therapeutic gas flow is restricted for the initial delay duration following receipt of a treatment initiation command. Upon the expiry of the initial delay duration, the controller increases therapeutic gas flow to the prescription pressure level.

13. 发明授权

US09919124B2 Delivery adaptor for ventilation system 有权
公开(公告)号：US09919124B2
公开(公告)日：2018-03-20
申请号：US13927008
申请日：2013-06-25
申请人： Breathe Technologies, Inc.
发明人： Samir S. Ahmad , Mark J. Zechmeister , Enrico Brambilla , Leonardo Alberto Baloa Welzien
IPC分类号： A61M16/00 , A62B7/00 , A61M16/08 , A61M16/16 , A61M16/20
CPC分类号： A61M16/0875 , A61M16/0066 , A61M16/0833 , A61M16/0858 , A61M16/16 , A61M16/20 , A61M2016/0027 , A61M2202/0208
摘要： In accordance with the present invention, there is provided is provided a tubing arrangement and associated connectors, including a delivery adaptor and a Y-connector, which may be used to facilitate the operative interface of a patient interface to a ventilator within a ventilation system. The delivery adaptor is connected between the outlet connector of the flow generator and the main delivery tube (i.e., the quad-lumen tube) in the ventilation system. The delivery adaptor functions to retain the pneumatic isolation of a sense line of the ventilation system from certain other lumens of the quad-lumen tube, and further connects one of the small lumens of the quad-lumen tube to an external oxygen source or an external humidification source. The oxygen or humidification is delivered to such lumen through the adaptor. The oxygen or humidification is then bled into the air stream at the outlet of such lumen which is at the Y-connector.

14. 发明授权

US09757532B2 Detection of patient interface disconnect for controlling continuous positive airway pressure therapy 有权
公开(公告)号：US09757532B2
公开(公告)日：2017-09-12
申请号：US14181435
申请日：2014-02-14
申请人： Breathe Technologies, Inc.
发明人： Leonardo Alberto Baloa Welzien , Mark Pielemeier , Samir S. Ahmad
IPC分类号： A61M16/00 , A61M16/06 , A61M16/20
CPC分类号： A61M16/0069 , A61M16/0051 , A61M16/024 , A61M16/06 , A61M16/107 , A61M16/208 , A61M2016/0027 , A61M2039/1005 , A61M2205/13 , A61M2205/3331 , A61M2205/42 , A61M2205/50 , A61M2205/52 , A61M2230/18 , A61M2230/40
摘要： Methods for detecting a patient disconnecting from a continuous positive airway pressure (CPAP) therapy device are disclosed. A cyclical pressure difference signal is derived based upon measurements from a patient interface pressure sensor and from a source pressure sensor. The pressure difference signal is integrated to generate a resultant integral signal for each respiratory cycle, which is comprised of at least one inspiratory phase and at least one expiratory phase as represented by the corresponding portions of the pressure difference signal. A pressure source of the CPAP therapy device is deactivated in response to a disconnect condition being evaluated from the integral signal. In one embodiment, the disconnect condition is the integral signal exceeding a predefined disconnect threshold. In other, it is a slope value corresponding to a rate of increase of the integral signal exceeding a predefined threshold for a predefined duration.

15. 发明授权

US09724017B2 Respiratory cycle patient ventilation flow limitation detection 有权
公开(公告)号：US09724017B2
公开(公告)日：2017-08-08
申请号：US13935362
申请日：2013-07-03
申请人： Breathe Technologies, Inc.
发明人： Leonardo Alberto Baloa Welzien , Samir S. Ahmad
IPC分类号： A61M16/00 , A61B5/085 , A61B5/087 , A61B5/00 , A61M16/06 , A61M16/08 , A61M16/20 , A61M16/10
CPC分类号： A61B5/085 , A61B5/087 , A61B5/4836 , A61B5/7278 , A61B5/7282 , A61M16/0051 , A61M16/0069 , A61M16/024 , A61M16/06 , A61M16/0858 , A61M16/107 , A61M16/205 , A61M16/206 , A61M2016/0027 , A61M2016/0039 , A61M2205/42 , A61M2205/7545
摘要： A single respiratory cycle flow limitation detection method is disclosed. A patient gas delivery signal is received from one or more sensors in pneumatic communication with a ventilation source and a patient ventilation interface to a patient airway. The patient gas delivery signal is representative of a measure of therapeutic gas being delivered to the patient airway at a given time instant, and spans the single patient respiratory cycle. A second derivative of the patient gas delivery signal is generated and a total number of zero crossings therein are counted. These zero crossings are representative of an inflection change in the patient gas delivery signal. A flow limitation indication corresponding to the identified flow limitation is generated when there are at least two zero crossings in the second derivative of the patient gas delivery signal. An angle of deformation representing early, late, or mid-cycle obstruction onsets is generated.

16. 发明申请

US20160045695A1 METHODS, SYSTEMS AND DEVICES FOR NON-INVASIVE OPEN VENTILATION WITH GAS DELIVERY NOZZLES WITH AN OUTER TUBE 审中-公开
标题翻译：方法，系统和装置，用于通过外管与气体输送喷嘴的非开启通气
公开(公告)号：US20160045695A1
公开(公告)日：2016-02-18
申请号：US14869600
申请日：2015-09-29
申请人： Breathe Technologies, Inc.
发明人： Gregory Kapust , Todd Allum , Anthony D. Wondka , Joseph Cipollone , Joey Aguirre , Darius Eghbal , Anthony Gerber
IPC分类号： A61M16/00 , A61M16/08 , A61M16/06
摘要： A non-invasive ventilation system may include at least one outer tube with a proximal lateral end of the outer tube adapted to extend to a side of a nose. The at least one outer tube may also include a throat section. At least one coupler may be located at a distal section of the outer tube for impinging at least one nostril and positioning the at least one outer tube relative to the at least one nostril. At least one jet nozzle may be positioned within the outer tube at the proximal lateral end and in fluid communication with a pressurized gas supply. At least one opening in the distal section may be adapted to be in fluid communication with the nostril. At least one aperture in the at least one outer tube may be in fluid communication with ambient air. The at least one aperture may be in proximity to the at least one jet nozzle.
摘要翻译：非侵入性通气系统可以包括至少一个外管，外管的近侧横端适于延伸到鼻的一侧。至少一个外管还可以包括喉部。至少一个联接器可以位于外管的远端部分处，用于冲击至少一个鼻孔，并且相对于至少一个鼻孔定位至少一个外管。至少一个喷嘴可以位于外管内的近端横向端并与加压气体源流体连通。远端部分中的至少一个开口可以适于与鼻孔流体连通。至少一个外管中的至少一个孔可以与环境空气流体连通。该至少一个孔口可以接近该至少一个喷嘴。

17. 发明申请

US20150068528A1 CONTINUOUS POSITIVE AIRWAY PRESSURE THERAPY TARGET PRESSURE COMFORT SIGNATURE 有权
标题翻译：连续正压航空压力治疗目标压力舒适签名
公开(公告)号：US20150068528A1
公开(公告)日：2015-03-12
申请号：US14482444
申请日：2014-09-10
申请人： BREATHE TECHNOLOGIES, INC.
发明人： SAMIR S. AHMAD , DONGBING WEI , MARK PEILEMEIER , LEONARDO ALBERTO BALOA-WELZIEN
IPC分类号： A61M16/00 , A61M16/06
CPC分类号： A61M16/0069 , A61M16/0051 , A61M16/026 , A61M16/06 , A61M16/107 , A61M2016/0021 , A61M2016/0027 , A61M2205/18 , A61M2205/3365 , A61M2205/42 , A61M2205/505
摘要： A comfort signature that naturally adapts delivered pressure to patient breathing by measuring comfort directly from the source is disclosed. Pressure is measured at the patient interface and is used to provide a comfortable and suitable target pressure adjustment that is synchronized with patient respiration.
摘要翻译：公开了通过直接从源头测量舒适度而自然地将输送压力传递给患者呼吸的舒适签名。在患者界面处测量压力，并用于提供与患者呼吸同步的舒适和合适的目标压力调节。

18. 发明申请

US20150011905A1 RESPIRATORY CYCLE PATIENT VENTILATION FLOW LIMITATION DETECTION 有权
标题翻译：呼吸循环患者通气流量限制检测
公开(公告)号：US20150011905A1
公开(公告)日：2015-01-08
申请号：US13935362
申请日：2013-07-03
申请人： Breathe Technologies, Inc.
发明人： Leonardo Alberto Baloa Welzien , Samir S. Ahmad
IPC分类号： A61B5/085 , A61B5/087 , A61B5/00 , A61M16/00
CPC分类号： A61B5/085 , A61B5/087 , A61B5/4836 , A61B5/7278 , A61B5/7282 , A61M16/0051 , A61M16/0069 , A61M16/024 , A61M16/06 , A61M16/0858 , A61M16/107 , A61M16/205 , A61M16/206 , A61M2016/0027 , A61M2016/0039 , A61M2205/42 , A61M2205/7545
摘要： A single respiratory cycle flow limitation detection method is disclosed. A patient gas delivery signal is received from one or more sensors in pneumatic communication with a ventilation source and a patient ventilation interface to a patient airway. The patient gas delivery signal is representative of a measure of therapeutic gas being delivered to the patient airway at a given time instant, and spans the single patient respiratory cycle. A second derivative of the patient gas delivery signal is generated and a total number of zero crossings therein are counted. These zero crossings are representative of an inflection change in the patient gas delivery signal. A flow limitation indication corresponding to the identified flow limitation is generated when there are at least two zero crossings in the second derivative of the patient gas delivery signal. An angle of deformation representing early, late, or mid-cycle obstruction onsets is generated.
摘要翻译：公开了一种呼吸循环流量限制检测方法。从一个或多个传感器接收患者气体输送信号，该传感器与通气源和患者通气道的患者通气接口气动连通。患者气体输送信号代表在给定时间瞬间输送到患者气道的治疗气体的量度，并跨越单个患者呼吸周期。产生患者气体输送信号的二阶导数，并计数其中的零交叉总数。这些过零点代表患者气体输送信号中的拐点变化。当在患者气体输送信号的二阶导数中存在至少两个过零点时，产生对应于所识别的流量限制的流量限制指示。产生代表早期，晚期或中期循环障碍物的变形角度。

19. 发明申请

US20140373835A1 DELIVERY ADAPTOR FOR VENTILATION SYSTEM 有权
标题翻译：用于通风系统的输送适配器
公开(公告)号：US20140373835A1
公开(公告)日：2014-12-25
申请号：US13927008
申请日：2013-06-25
申请人： Breathe Technologies, Inc.
发明人： Samir S. Ahmad , Mark J. Zechmeister , Enrico Brambilla , Leonardo Alberto Baloa Welzien
IPC分类号： A61M16/08 , A61M16/20 , A61M16/16
CPC分类号： A61M16/0875 , A61M16/0066 , A61M16/0833 , A61M16/0858 , A61M16/16 , A61M16/20 , A61M2016/0027 , A61M2202/0208
摘要： In accordance with the present invention, there is provided is provided a tubing arrangement and associated connectors, including a delivery adaptor and a Y-connector, which may be used to facilitate the operative interface of a patient interface to a ventilator within a ventilation system. The delivery adaptor is connected between the outlet connector of the flow generator and the main delivery tube (i.e., the quad-lumen tube) in the ventilation system. The delivery adaptor functions to retain the pneumatic isolation of a sense line of the ventilation system from certain other lumens of the quad-lumen tube, and further connects one of the small lumens of the quad-lumen tube to an external oxygen source or an external humidification source. The oxygen or humidification is delivered to such lumen through the adaptor. The oxygen or humidification is then bled into the air stream at the outlet of such lumen which is at the Y-connector.
摘要翻译：根据本发明，提供了一种管道装置和相关联的连接器，包括输送适配器和Y型连接器，其可以用于促进患者接口与通气系统内的呼吸机的操作界面。输送适配器连接在流量发生器的出口连接器和通风系统中的主输送管（即四腔管）之间。输送适配器用于保持通气系统的感测线与四腔管的某些其他腔的气动隔离，并且还将四腔管中的一个小腔连接到外部氧源或外部氧源加湿源氧气或加湿通过适配器输送到这样的内腔。然后将氧气或加湿物排放到位于Y型连接器处的这种管腔出口处的空气流中。

20. 发明申请

US20140283834A1 PORTABLE VENTILATOR SECRETION MANAGEMENT SYSTEM 有权
标题翻译：便携式通风机分配管理系统
公开(公告)号：US20140283834A1
公开(公告)日：2014-09-25
申请号：US13849443
申请日：2013-03-22
申请人： Breathe Technologies, Inc.
发明人： Samir S. Ahmad , Leonardo Alberto Baloa Welzien
IPC分类号： A61M16/00 , A61M16/06 , A61M16/08 , A61M16/20
CPC分类号： A61M16/0069 , A61M16/00 , A61M16/0051 , A61M16/026 , A61M16/06 , A61M16/101 , A61M16/107 , A61M16/202 , A61M2016/0027 , A61M2016/0033 , A61M2202/0208 , A61M2205/50 , A61M2205/505 , A61M2205/8206
摘要： A patient ventilator secretion management system is disclosed. The system has a valve with an input in pneumatic communication with a therapeutic breathing gas source. The valve has variable positions, each of which corresponds to a specific flow rate of gas being output therefrom. A patient ventilation interface is in pneumatic communication with the valve over a gas delivery circuit. A controller in communication with the valve regulates the position thereof. The controller sequentially switches the valve from one of the variable positions to another to output a first range of fluctuating flow rates of gas for delivery to the patient ventilation interface during at least a selected one of patient expiratory and inspiratory phases.
摘要翻译：公开了一种患者呼吸机分泌物管理系统。该系统具有与治疗呼吸气体源气动连通的输入的阀。阀具有可变位置，每个位置对应于从其输出的气体的特定流量。患者通气接口与气体输送电路上的阀气动连通。与阀连通的控制器调节其位置。所述控制器顺序地将所述阀从所述可变位置之一转换到另一位置，以在至少所选择的一个患者呼气和吸气阶段期间输出气体的波动流速的第一范围，用于输送到患者通气界面。

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