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11. 发明申请

US20100063383A1 CATHETER FOR MAGNETIC RESONANCE GUIDED PROCEDURES 有权
标题翻译：磁共振引导程序导管
公开(公告)号：US20100063383A1
公开(公告)日：2010-03-11
申请号：US12557840
申请日：2009-09-11
申请人： Kevan ANDERSON , Graham WRIGHT
发明人： Kevan ANDERSON , Graham WRIGHT
IPC分类号： A61B5/055 , A61M29/00 , A61M25/00
CPC分类号： A61M25/01 , A61M25/0127 , A61M2025/0166 , A61M2205/3515 , G01R33/287 , G01R33/288 , G01R33/34084
摘要： A catheter for magnetic resonance (MR) guided procedures comprising: a catheter body having a lumen for accommodating an intravascular device; a magnetic coupling component in the catheter body, the magnetic coupling component being designed to magnetically couple with a conductive length on the intravascular device, the magnetic coupling resulting in a signal; the catheter having a connection to deliver the signal to a processor.
摘要翻译：一种用于磁共振（MR）引导程序的导管，包括：导管体，其具有用于容纳血管内装置的内腔; 导管主体中的磁耦合部件，所述磁耦合部件设计成与血管内装置上的导电长度磁耦合，所述磁耦合产生信号; 导管具有将信号传送到处理器的连接。

12. 发明授权

US09050450B2 Ultrasound therapy transducer head with temperatire control structure 有权
标题翻译：超声波治疗传感头具有温度控制结构
公开(公告)号：US09050450B2
公开(公告)日：2015-06-09
申请号：US13897693
申请日：2013-05-20
申请人： Sunnybrook Health Sciences Centre
发明人： Kullervo H. Hynynen , Junho Song
IPC分类号： A61N7/02 , A61B8/00 , B06B3/00 , A61B18/00 , A61N7/00
CPC分类号： A61N7/02 , A61B8/546 , A61B2018/00011 , A61B2018/00642 , A61N2007/0078 , B06B3/00
摘要： An ultrasound therapy transducer head comprises an ultrasound source emitting ultrasonic radiation, the ultrasound source comprising a plurality of transducer elements, integrated driving electronics coupled to the transducer elements, the electronics generating at least one output ultrasound waveform and driving at least some of the transducer elements independently based on the at least one output ultrasound waveform and temperature control structure providing cooling for the electronics.
摘要翻译：超声波治疗换能器头包括发射超声波辐射的超声源，所述超声源包括多个换能器元件，耦合到所述换能器元件的集成驱动电子器件，所述电子元件生成至少一个输出超声波形并且驱动至少一些所述换能器元件独立地基于至少一个输出超声波形和温度控制结构，为电子设备提供冷却。

13. 发明申请

US20140323877A1 MEDICAL IMAGING PROBE WITH ROTARY ENCODER 有权
标题翻译：具有旋转编码器的医学成像探头
公开(公告)号：US20140323877A1
公开(公告)日：2014-10-30
申请号：US14263862
申请日：2014-04-28
申请人： SUNNYBROOK HEALTH SCIENCES CENTRE
发明人： Brian COURTNEY , Nigel Robert MUNCE , Amandeep Singh THIND , Victor Xiao Dong YANG , Francis Stuart FOSTER
IPC分类号： A61B5/00
CPC分类号： A61B5/0035 , A61B1/00112 , A61B1/00172 , A61B1/00183 , A61B5/0062 , A61B5/0066 , A61B5/0084 , A61B5/0095 , A61B5/6852 , A61B5/7207 , A61B5/742 , A61B8/12 , A61B8/4281 , A61B8/445 , A61B8/4461 , A61B8/483 , A61B8/5238 , A61B8/5292 , A61B8/543 , G02B6/3604 , G02B23/24 , G10K11/002
摘要： The present invention provides minimally invasive imaging probe having an optical encoder integrated therewith for accurately measuring or estimating the rotational velocity near the distal end of the medical device, such as an imaging probe which undergoes rotational movement during scanning of surrounding tissue in bodily lumens and cavities.
摘要翻译：本发明提供了具有与其集成的光学编码器的微创成像探针，用于精确地测量或估计医疗装置的远端附近的旋转速度，例如在身体流明和空腔中的周围组织扫描期间经历旋转运动的成像探针。

14. 发明申请

US20140323860A1 IMAGING PROBE WITH COMBINED ULTRASOUND AND OPTICAL MEANS OF IMAGING 审中-公开
标题翻译：具有组合超声和成像光学成像的成像探针
公开(公告)号：US20140323860A1
公开(公告)日：2014-10-30
申请号：US14283052
申请日：2014-05-20
申请人： SUNNYBROOK HEALTH SCIENCES CENTRE
发明人： Brian COURTNEY , Nigel Robert MUNCE , Amandeep Singh THIND , Victor Xiao Dong YANG , Francis Stuart FOSTER
IPC分类号： A61B5/00 , A61B8/08
CPC分类号： A61B5/0035 , A61B1/00112 , A61B1/00172 , A61B1/00183 , A61B5/0062 , A61B5/0066 , A61B5/0084 , A61B5/0095 , A61B5/6852 , A61B5/7207 , A61B5/742 , A61B8/12 , A61B8/4281 , A61B8/445 , A61B8/4461 , A61B8/483 , A61B8/5238 , A61B8/5292 , A61B8/543 , G02B6/3604 , G02B23/2423 , G10K11/002
摘要： The present invention provides an imaging probe for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and optical coherence tomography. The imaging probes structures using high resolution imaging use combined high frequency ultrasound (IVUS) and optical imaging methods such as optical coherence tomography (OCT) and to accurate co-registering of images obtained from ultrasound image signals and optical image signals during scanning a region of interest.
摘要翻译：本发明提供了一种用于使用高分辨率成像（包括高频超声和光学相干断层扫描）来对哺乳动物组织和结构进行成像的成像探针。使用高分辨率成像的成像探针结构使用组合高频超声（IVUS）和诸如光学相干断层摄影（OCT）的光学成像方法，并且在扫描区域内的超声图像信号和光学图像信号获得的图像的精确共同配准利益。

15. 发明授权

US08784321B2 Imaging probe with combined ultrasound and optical means of imaging 有权
标题翻译：具有组合超声和成像光学手段的成像探头
公开(公告)号：US08784321B2
公开(公告)日：2014-07-22
申请号：US12010208
申请日：2008-01-22
申请人： Brian Courtney , Nigel Robert Munce , Amandeep Singh Thind , Victor Xiao Dong Yang , Francis Stuart Foster
发明人： Brian Courtney , Nigel Robert Munce , Amandeep Singh Thind , Victor Xiao Dong Yang , Francis Stuart Foster
IPC分类号： A61B5/05
CPC分类号： A61B5/0035 , A61B1/00112 , A61B1/00172 , A61B1/00183 , A61B5/0062 , A61B5/0066 , A61B5/0084 , A61B5/0095 , A61B5/6852 , A61B5/7207 , A61B5/742 , A61B8/12 , A61B8/4281 , A61B8/445 , A61B8/4461 , A61B8/483 , A61B8/5238 , A61B8/5292 , A61B8/543 , G02B6/3604 , G02B23/24 , G10K11/002
摘要： The present invention provides an imaging probe for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and optical coherence tomography. The imaging probes structures using high resolution imaging use combined high frequency ultrasound (IVUS) and optical imaging methods such as optical coherence tomography (OCT) and to accurate co-registering of images obtained from ultrasound image signals and optical image, signals during scanning a region of interest.
摘要翻译：本发明提供了一种用于使用高分辨率成像（包括高频超声和光学相干断层扫描）来对哺乳动物组织和结构进行成像的成像探针。使用高分辨率成像的成像探针结构使用组合高频超声（IVUS）和诸如光学相干断层摄影（OCT）的光学成像方法，并且在扫描区域期间精确地共同从超声图像信号和光学图像获得的图像信号出于兴趣。

16. 发明授权

US08712506B2 Medical imaging probe with rotary encoder 有权
标题翻译：带旋转编码器的医用成像探头
公开(公告)号：US08712506B2
公开(公告)日：2014-04-29
申请号：US12010207
申请日：2008-01-22
申请人： Brian Courtney , Nigel Robert Munce , Amandeep Singh Thind , Victor Xiao Dong Yang , Francis Stuart Foster
发明人： Brian Courtney , Nigel Robert Munce , Amandeep Singh Thind , Victor Xiao Dong Yang , Francis Stuart Foster
IPC分类号： A61B1/00
CPC分类号： A61B5/0035 , A61B1/00112 , A61B1/00172 , A61B1/00183 , A61B5/0062 , A61B5/0066 , A61B5/0084 , A61B5/0095 , A61B5/6852 , A61B5/7207 , A61B5/742 , A61B8/12 , A61B8/4281 , A61B8/445 , A61B8/4461 , A61B8/483 , A61B8/5238 , A61B8/5292 , A61B8/543 , G02B6/3604 , G02B23/24 , G10K11/002
摘要： The present invention provides minimally invasive imaging probe having an optical encoder integrated therewith for accurately measuring or estimating the rotational velocity near the distal end of the medical device, such as an imaging probe which undergoes rotational movement during scanning of surrounding tissue in bodily lumens and cavities.
摘要翻译：本发明提供了具有与其集成的光学编码器的微创成像探针，用于精确地测量或估计医疗装置的远端附近的旋转速度，例如在身体流明和空腔中的周围组织扫描期间经历旋转运动的成像探针。

17. 发明授权

US08417005B1 Method for automatic three-dimensional segmentation of magnetic resonance images 有权
标题翻译：磁共振图像自动三维分割方法
公开(公告)号：US08417005B1
公开(公告)日：2013-04-09
申请号：US13233570
申请日：2011-09-15
申请人： Anne L Martel , Cristina Gallego
发明人： Anne L Martel , Cristina Gallego
IPC分类号： G06K9/00 , G01N23/00
CPC分类号： G01R33/5608 , G06T7/12 , G06T7/143 , G06T7/149 , G06T2207/10088 , G06T2207/20056 , G06T2207/20128 , G06T2207/30068
摘要： A method for automatically segmenting a volume-of-interest representative of a subject's breast from a three-dimensional magnetic resonance image is provided. The three-dimensional image may include a plurality of spatially contiguous two-dimensional images. The image is converted to a monogenic signal, which is analyzed to determine locations in the image that correspond to maximal phase congruency in the monogenic signal. The orientation of each of these locations is determined and used along with the locations to estimate a boundary surface of the volume-of-interest. The estimated surface may be used to segment the image directly, or to generate a surface model, such as a statistical shape model, that is used to segment the image. This provided method is robust to segmenting the subject's breast, even at the chest-wall boundary in images with lower contrast-to-noise ratio between breast tissue and tissues in and around the chest wall.
摘要翻译：提供了一种用于从三维磁共振图像自动分割对象胸部的兴趣体积代表的方法。三维图像可以包括多个空间连续的二维图像。图像被转换为单基因信号，其被分析以确定对应于单基因信号中的最大相位一致性的图像中的位置。确定每个这些位置的方向并与位置一起使用以估计感兴趣体积的边界表面。估计的表面可以用于直接分割图像，或者用于生成用于分割图像的表面模型，例如统计形状模型。这种提供的方法对于分割受试者的乳房是鲁棒的，即使在乳房组织和胸壁周围组织之间具有较低对比度对比度的图像的胸壁边界。

18. 发明授权

US08192362B2 Methods of monitoring cellular death using low frequency ultrasound 有权
标题翻译：使用低频超声监测细胞死亡的方法
公开(公告)号：US08192362B2
公开(公告)日：2012-06-05
申请号：US11455005
申请日：2006-06-15
申请人： Michael Kolios , Gregory J. Czarnota , Michael D. Sherar , Adam Tunis , John Hunt
发明人： Michael Kolios , Gregory J. Czarnota , Michael D. Sherar , Adam Tunis , John Hunt
IPC分类号： A61B8/00
CPC分类号： A61B8/08 , A61B2090/378 , A61F7/00 , A61N5/062 , A61N5/10
摘要： A method of detecting cellular damage within a subject comprises transmitting low frequency ultrasound (20 MHz or below) into a selected site within the subject wherein the selected site has been exposed to a stress capable of causing cellular death at the selected site. At least a portion of ultrasound backscattered from the ultrasound transmitted into the selected site is received. The received backscattered ultrasound is compared to a control backscatter measurement. An increase or a decrease in intensity or spectral slope of the received backscattered ultrasound when compared to the control backscatter measurement indicates cellular death or damage at the selected site within the subject.
摘要翻译：一种检测受试者内的细胞损伤的方法包括将低频超声（20MHz或更低）传输到受试者内的选定部位，其中所选择的部位已暴露于能够在所选位点引起细胞死亡的应激。从被发送到所选位置的超声波向后散射的超声波的至少一部分被接收。将接收的反向散射超声波与控制反向散射测量进行比较。与控制反向散射测量相比，接收的反向散射超声的强度或光谱斜率的增加或减小表明在受试者内的选定部位处的细胞死亡或损伤。

19. 发明授权

US08073526B2 Method and system for computerized drawing and writing during functional magnetic resonance imaging 有权
标题翻译：功能磁共振成像期间计算机绘图和写入的方法和系统
公开(公告)号：US08073526B2
公开(公告)日：2011-12-06
申请号：US11707266
申请日：2007-02-16
申请人： Simon James Graham , Richard Mraz , Nicole Baker , Ian Clarkson , Fred Tam
发明人： Simon James Graham , Richard Mraz , Nicole Baker , Ian Clarkson , Fred Tam
IPC分类号： A61B5/055
CPC分类号： G01R33/4806 , G01R33/28 , G01R33/283 , G06F3/03547 , G06F3/045
摘要： The present invention provides a method and device to record and visualize drawing and writing movements during functional magnetic resonance imaging (fMRI) of brain activity. The system includes a touch-sensitive tablet, an elevated mounting platform, a stylus, and a controller box, as well as the necessary cabling and software. All equipment residing inside the magnet room is non-ferromagnetic and does not interfere with scanner operation and does not affect fMRI data quality. Individuals lying inside the scanner interact with device in a natural, intuitive way, similar to writing with pen and paper. Drawing motions captured by the tablet are displayed through a pair of fMRI-compatible goggles or by using a projector and screen. Other visual stimuli can be concurrently presented with the drawing motions for the purpose of assessing specific aspects of human behavior. The system allows for a plurality of experiments to be performed, all while brain activity is measured and recorded.
摘要翻译：本发明提供了一种用于在大脑活动的功能磁共振成像（fMRI）期间记录和可视化绘图和书写移动的方法和装置。该系统包括触敏平板电脑，高架安装平台，触笔和控制箱，以及必要的布线和软件。磁体室内的所有设备都是非铁磁性的，不影响扫描仪的运行，不影响fMRI的数据质量。位于扫描仪内的个人以自然，直观的方式与设备进行交互，类似于使用笔和纸的书写。由平板电脑捕获的绘图动作通过一对fMRI兼容的护目镜或使用投影仪和屏幕显示。其他视觉刺激可以同时呈现绘图动作，目的是评估人类行为的具体方面。该系统允许执行多个实验，同时测量和记录脑活动。

20. 发明授权

US07687792B2 X-ray light valve based digital radiographic imaging systems 有权
标题翻译：基于X射线光阀的数字放射成像系统
公开(公告)号：US07687792B2
公开(公告)日：2010-03-30
申请号：US11704371
申请日：2007-02-09
申请人： John Alan Rowlands , Christie Ann Webster , Ivaylo Koprinarov , Peter Oakham , Stephen Germann , James Alexander Robert Stiles
发明人： John Alan Rowlands , Christie Ann Webster , Ivaylo Koprinarov , Peter Oakham , Stephen Germann , James Alexander Robert Stiles
IPC分类号： H05G1/64
CPC分类号： G01T1/246 , G01N2223/03 , G01N2223/50 , G02F1/1354 , G02F2001/1352
摘要： The present invention provides a digital x-ray radiographic imaging system. The system is based on a photoconductive detector and an electro-optic light modulator, where the photoconductive detector layer absorbs x-rays that have passed through an object to form an exposure of the object. The absorbed x-rays create a static optical image, which is stored in the electro-optic light modulator, allowing the capture of the optical image to continue over longer time. The optical image is digitized using a scanning system and an external light source. The image is then processed and stored by a computer. After the optical image is recorded, an erasing mechanism is used to reset the system before a new exposure is made.
摘要翻译：本发明提供一种数字X射线照相成像系统。该系统基于光电导检测器和电光调制器，其中光电导检测器层吸收已经通过物体的X射线以形成物体的曝光。吸收的X射线产生静电光学图像，其被存储在电光调制器中，允许光学图像的捕获在更长时间内继续。光学图像使用扫描系统和外部光源进行数字化。然后图像被计算机处理和存储。在记录光学图像之后，在进行新的曝光之前，使用擦除机构重置系统。

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