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    • 18. 发明授权
    • Method of manufacturing of hollow fiber cartridge with porous ring
    • 具有多孔环的中空纤维筒的制造方法
    • US5531848A
    • 1996-07-02
    • US443187
    • 1995-05-17
    • Paul D. BrindaLouis C. Cosentino
    • Paul D. BrindaLouis C. Cosentino
    • B01D63/02B01D63/04B01D65/00
    • B01D63/021B01D63/02B01D63/046B01D65/00B01D2313/20
    • A method of sealingly coupling a hollow fiber bundle having first and seconds ends to a porous collar having first and second peripheral edges, at least one of which is coupled to the inner ledge of a casing for encasing said bundle of hollow fibers is disclosed. The method broadly includes providing a porous collar having first and second outer peripheral edges; providing a casing having first and second longitudinal ends, the casing defining a central chamber, the chamber having first and second open ends wherein the longitudinal ends of the casing each include an inner lip proximal to the open end; coupling the first outer peripheral edge of the porous collar to the inner lip of the casing; retaining a bundle of hollow fibers having first and second longitudinal ends within the chamber; permeating the longitudinal ends of the hollow fiber bundle with a fluid impermeable material; joining the porous collar to the fluid impermeable material by penetration of the material into the porous collar; and curing the fluid impermeable material. The method provides a fluid impermeable seal between the casing and the individual hollow fibers. The seal prevents the unfiltered fluid from coming into contact with filtrate and provides a strong bond that is impervious to dry heat and steam sterilization at temperatures ranging from 100.degree. C. to 150.degree. C. and pressures from 10 psi to 60 psi.
    • 公开了一种将具有第一和第二端的中空纤维束密封地连接到具有第一和第二周边边缘的多孔环,其中至少一个中空纤维束联接到用于封装所述中空纤维束的壳体的内壁。 该方法广泛地包括提供具有第一和第二外围边缘的多孔轴环; 提供具有第一和第二纵向端部的壳体,所述壳体限定中心室,所述腔室具有第一和第二开放端,其中所述壳体的纵向端部包括靠近所述开口端的内唇缘; 将多孔环的第一外围边缘连接到壳体的内唇缘; 保持一束中空纤维,其在腔室内具有第一和第二纵向端部; 用流体不渗透材料渗透中空纤维束的纵向端部; 通过将所述材料穿入所述多孔环中将所述多孔环接合到所述流体不可渗透材料上; 并固化不透液体的材料。 该方法在壳体和各个中空纤维之间提供流体不可渗透的密封。 密封件防止未过滤的流体与滤液接触并提供强力的粘合,其在100℃至150℃的温度和10psi至60psi的压力下不受干热和蒸汽灭菌。