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161. 发明申请

US20120100586A1 BIOPROCESSING 有权
标题翻译：生物学
公开(公告)号：US20120100586A1
公开(公告)日：2012-04-26
申请号：US13293971
申请日：2011-11-10
申请人： Marshall Medoff , Thomas Craig Masterman , Harrison D. Medoff
发明人： Marshall Medoff , Thomas Craig Masterman , Harrison D. Medoff
IPC分类号： C12P7/02 , C12N1/00
CPC分类号： C12M45/07 , C12M25/00 , C12N11/00 , C12N11/14 , C12P7/02 , C12P7/06 , C12P7/065 , C12P7/10 , C12P7/14 , C12P19/02 , C12P19/14 , C12P2203/00 , Y02E50/16 , Y02E50/17 , Y02P30/20
摘要： Functionalized substrate materials, for example inorganic particles and/or synthetic polymeric particles, are used to enhance bioprocesses such as saccharification and fermentation.
摘要翻译：功能化底物材料，例如无机颗粒和/或合成聚合物颗粒，用于增强生物过程如糖化和发酵。

162. 发明申请

US20120083019A1 Use of Glycoside Hydrolase 61 Family Proteins in Processing of Cellulose 有权
标题翻译：糖苷水解酶61家族蛋白在纤维素加工中的应用
公开(公告)号：US20120083019A1
公开(公告)日：2012-04-05
申请号：US13215193
申请日：2011-08-22
申请人： Dipnath Baidyaroy , Louis Clark , Onorato Campopiano , Kripa Rao , Lorand Szabo , Janos Torok
发明人： Dipnath Baidyaroy , Louis Clark , Onorato Campopiano , Kripa Rao , Lorand Szabo , Janos Torok
IPC分类号： C12P19/14 , C12P1/00 , C12P7/14 , C12N9/42
CPC分类号： C12P19/02 , C12N9/242 , C12N9/2434 , C12P7/10 , C12P7/14 , C12P19/14 , Y02E50/16 , Y02P20/52
摘要： The invention provides recombinant GH61 proteins obtained from Myceliophtora thermophila, and nucleic acids that encode such proteins. The invention also provides protein fractions isolated from M. thermophila supernatant that have GH61 protein activity. These preparations can be used to increase yield of products from reactions in which a cellulose-containing substrate undergoes saccharification by one or more cellulase enzymes, such as endoglucanase, β-glucosidase, or cellobiohydrolase. Combinations of GH61 protein and cellulases can be used to break down cellulosic biomass into fermentable sugars in the production of ethanol.
摘要翻译：本发明提供了从嗜热丝霉菌（Myceliophtora thermophila）获得的重组GH61蛋白质和编码这种蛋白质的核酸。本发明还提供从具有GH61蛋白活性的嗜热绵羊嗜热上清液分离的蛋白质级分。可以使用这些制剂从含有纤维素的底物通过一种或多种纤维素酶如内切葡聚糖酶，葡糖苷酶或纤维二糖水解酶进行糖化的反应来提高产品的产量。 GH61蛋白和纤维素酶的组合可用于在生产乙醇中将纤维素生物质分解成可发酵糖。

163. 发明授权

US08133711B2 BGL7 beta-glucosidase and nucleic acids encoding the same 有权
标题翻译： BGL7β-葡糖苷酶和编码相同的核酸
公开(公告)号：US08133711B2
公开(公告)日：2012-03-13
申请号：US12145023
申请日：2008-06-24
申请人： Nigel Dunn-Coleman , Michael Ward
发明人： Nigel Dunn-Coleman , Michael Ward
IPC分类号： C12N9/42 , C12N1/20 , C12N15/00 , C12N1/14 , C12Q1/00 , C12P21/04 , C07H21/04
CPC分类号： C12N9/2437 , C11D3/386 , C11D3/38645 , C12N9/244 , C12N9/2445 , C12N15/1137 , C12N2310/11 , C12P7/14 , C12P19/02 , C12P19/14 , C12Y302/01004 , C12Y302/01021 , Y02E50/17
摘要： The present invention provides BGL7 polypeptides with the biological activity of a β-glucosidase and a method of producing a recombinant enzyme having β-glucosidase activity.
摘要翻译：本发明提供了具有葡糖苷酶的生物学活性的BGL7多肽和具有葡糖苷酶活性的重组酶的生产方法。

164. 发明申请

US20120045811A1 EGVII Endoglucanase and Nucleic Acids Encoding the Same 有权
标题翻译： EGVII内切葡聚糖酶和编码其的核酸
公开(公告)号：US20120045811A1
公开(公告)日：2012-02-23
申请号：US13286955
申请日：2011-11-01
申请人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
发明人： Nigel Dunn-Coleman , Frits Goedegebuur , Michael Ward , Jian Yao
IPC分类号： C12P7/14 , C12N15/63 , C12N1/19 , C07H21/02 , C12N1/00 , C12N1/15 , C12N15/56 , C12N9/42
CPC分类号： C12N9/2437 , C11D3/38 , C11D3/38636 , C11D3/38645 , C12N9/2445 , C12N15/1137 , C12N2310/11 , C12P7/10 , C12P7/14 , C12P19/02 , C12P19/14 , C12P2201/00 , C12Y302/01004 , Y02E50/16 , Y02E50/17
摘要： The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
摘要翻译：本发明提供了一种命名为egl7的新型内切葡聚糖酶核酸序列和相应的EGVII氨基酸序列。本发明还提供了包含编码EGVII的核酸序列，重组EGVII蛋白的表达载体和宿主细胞及其制备方法。

165. 发明申请

US20110318790A1 XYLOSE ISOMERASE GENES AND THEIR USE IN FERMENTATION OF PENTOSE SUGARS 有权
标题翻译： XYLOSE异黄酮基因及其在发酵糖中的应用
公开(公告)号：US20110318790A1
公开(公告)日：2011-12-29
申请号：US13142124
申请日：2009-12-24
申请人： Aloysius Wilhelmus Rudolphus Hubertus Teunissen , Johannes Adrianus Maria De Bont
发明人： Aloysius Wilhelmus Rudolphus Hubertus Teunissen , Johannes Adrianus Maria De Bont
IPC分类号： C12P1/02 , C12N1/15 , C12P7/06 , C12P7/56 , C12P7/42 , C12P7/54 , C12P7/40 , C12P7/46 , C12P7/48 , C12P13/04 , C12P7/18 , C12P5/02 , C12P7/20 , C12P7/52 , C12P7/16 , C12P17/18 , C12N1/19
CPC分类号： C12N9/90 , C12N9/92 , C12N15/52 , C12P5/026 , C12P7/06 , C12P7/14 , C12P7/16 , C12P7/18 , C12P7/20 , C12P7/40 , C12P7/42 , C12P7/46 , C12P7/48 , C12P7/52 , C12P7/54 , C12P7/56 , C12P13/04 , C12P17/10 , C12P35/00 , C12Y503/01005 , Y02E50/10 , Y02E50/16 , Y02E50/17 , Y02P20/52
摘要： The present invention relates to eukaryotic cells which have the ability to isomerise xylose directly into xylulose. The cells have acquired this ability by transformation with nucleotide sequences coding for a xylose isomerase that has one or more specific sequence elements typical for isomerases having the ability of functional expression in yeasts, such as e.g. xylose isomerases obtainable from a bacterium of the genera Clostridiumand Fusobacteriumor a tunicate form the genus Ciona. The cell preferably is a yeast or a filamentous fungus, more preferably a yeast is capable of anaerobic alcoholic fermentation. The may further comprise one or more genetic modifications that increase the flux of the pentose phosphate pathway, reduce unspecific aldose reductase activity, confer to the cell the ability to increase the specific xylulose kinase activity, convert L-arabinose into D-xylulose 5-phosphate, increase transport of at least one of xylose and arabinose into the host cell, decrease sensitivity to catabolite repression, increase tolerance to ethanol, osmolarity or organic acids; and/or reduce production of by-products. The cell preferably is a cell that has the ability to produce a fermentation product such as ethanol, lactic acid, 3-hydroxy-propionic acid, acrylic acid, acetic acid, succinic acid, citric acid, amino acids, 1,3-propane-diol, ethylene, glycerol, β-lactam antibiotics and cephalosporins. The invention further relates to processes for producing these fermentation products wherein a cell of the invention is used to ferment xylose into the fermentation products.
摘要翻译：本发明涉及具有将木糖直接异构化成木酮糖的能力的真核细胞。细胞通过用编码木糖异构酶的核苷酸序列转化获得了这种能力，该木糖异构酶具有典型的具有在酵母中功能表达能力的异构酶的特定序列元件，木糖异构酶可从Clostridium和Fusobacterium属的细菌获得，或者是Ciona属的一种细丝。细胞优选是酵母或丝状真菌，更优选酵母能够进行厌氧酒精发酵。可进一步包含增加戊糖磷酸途径通量的一种或多种遗传修饰，减少非特异性醛糖还原酶活性，赋予细胞增加特异性木酮糖激酶活性的能力，将L-阿拉伯糖转化为D-木酮糖-5-磷酸增加至少一种木糖和阿拉伯糖到宿主细胞中的转运，降低对分解代谢物抑制的敏感性，增加对乙醇的耐受性，渗透压或有机酸的转运; 和/或减少副产物的生产。细胞优选是具有产生发酵产物如乙醇，乳酸，3-羟基 - 丙酸，丙烯酸，乙酸，琥珀酸，柠檬酸，氨基酸，1,3-丙烷 - 二醇，乙烯，甘油，β-内酰胺抗生素和头孢菌素。本发明还涉及生产这些发酵产物的方法，其中本发明的细胞用于将木糖发酵成发酵产物。

166. 发明授权

US07972824B2 Microbial fermentation of gaseous substrates to produce alcohols 有权
标题翻译：气态底物的微生物发酵产生醇
公开(公告)号：US07972824B2
公开(公告)日：2011-07-05
申请号：US12296300
申请日：2007-04-05
申请人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Matthew Rowe
发明人： Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Matthew Rowe
IPC分类号： C12P7/02 , C12P7/06 , C12P3/00
CPC分类号： C12P7/14 , C12P7/54 , Y02E50/17
摘要： The present invention relates to methods for increasing the efficiency of anaerobic fermentation processes (1) that produce acetate as a by-product in addition to a desired product, and (2) that can utilize hydrogen and/or carbon dioxide in the fermentation. The method comprises the steps of converting acetate produced by the fermentation process into hydrogen gas and carbon dioxide gas, and utilizing hydrogen gas and/or carbon dioxide gas obtained from the acetate conversion in the anaerobic fermentation process. In particular aspects, the invention relates to processes of producing alcohols, particularly ethanol.
摘要翻译：本发明涉及提高厌氧发酵方法（1）的效率的方法（1），除了所需产物外，还可以生产作为副产物的乙酸酯，和（2）可以在发酵中利用氢和/或二氧化碳。该方法包括以下步骤：将通过发酵过程产生的乙酸转化为氢气和二氧化碳气体，并在厌氧发酵过程中利用由乙酸酯转化得到的氢气和/或二氧化碳气体。在具体方面，本发明涉及生产醇，特别是乙醇的方法。

167. 发明申请

US20110126448A1 Process, Plant, and Biofuel For Integrated Biofuel Production 审中-公开
标题翻译：生物燃料生产过程，植物和生物燃料
公开(公告)号：US20110126448A1
公开(公告)日：2011-06-02
申请号：US12815853
申请日：2010-06-15
申请人： Jean-Charles Dumenil
发明人： Jean-Charles Dumenil
IPC分类号： C10L1/00 , C12P7/10 , C12P7/64 , C12M1/00 , B01J8/00
CPC分类号： C12P7/649 , C10L1/04 , C12P7/10 , C12P7/14 , C12P2203/00 , Y02E50/13 , Y02E50/16 , Y02P20/125
摘要： This invention relates to a process, a plant, and a biofuel for integrated biofuel production, such as with biogasoline, biodiesel, and/or sugar product. The integrated process includes the step of removing hexose from a feedstock to form a lignocellulosic material. The process also includes the step of converting the hexose to a biogasoline and/or a biodiesel material, and the step of depolymerizing lignocellulosic material to form pentose and a residue. The process also includes the step of converting the pentose to a biogasoline and/or a biodiesel material.
摘要翻译：本发明涉及用于综合生物燃料生产的方法，植物和生物燃料，例如与生物汽油，生物柴油和/或糖产品。整合方法包括从原料中除去己糖以形成木质纤维素材料的步骤。该方法还包括将己糖转化为生物汽油和/或生物柴油材料的步骤，以及解聚木质纤维素材料以形成戊糖和残余物的步骤。该方法还包括将戊糖转化为生物汽油和/或生物柴油材料的步骤。

168. 发明申请

US20110039317A1 PROCESSING BIOMASS 有权
公开(公告)号：US20110039317A1
公开(公告)日：2011-02-17
申请号：US12912518
申请日：2010-10-26
申请人： Marshall MEDOFF
发明人： Marshall MEDOFF
IPC分类号： C12P7/02 , C12P1/00
CPC分类号： D21B1/10 , C08H8/00 , C08L1/02 , C08L97/02 , C10G1/00 , C10G3/00 , C10G15/00 , C10G32/00 , C10G49/12 , C10G2300/1014 , C10L1/02 , C10L5/44 , C10L2200/0469 , C10L2250/04 , C10L2290/26 , C10L2290/36 , C12M21/04 , C12M21/12 , C12M45/00 , C12M45/02 , C12M45/20 , C12N9/2405 , C12P3/00 , C12P5/00 , C12P7/02 , C12P7/04 , C12P7/10 , C12P7/14 , C12P7/16 , C12P19/02 , C12P19/14 , C12P2201/00 , C12P2203/00 , D21H11/08 , F01K7/16 , F01K9/00 , F01K13/02 , F22B1/00 , Y02E50/10 , Y02E50/14 , Y02E50/16 , Y02E50/17 , Y02E50/30 , Y02E50/32 , Y02E50/343 , Y02P30/20 , C08L2666/02
摘要： Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to produce ethanol and/or butanol, e.g., by fermentation.

169. 发明授权

US07888082B2 Process for producing ethanol from corn dry milling 有权
标题翻译：从玉米干磨中生产乙醇的方法
公开(公告)号：US07888082B2
公开(公告)日：2011-02-15
申请号：US12324015
申请日：2008-11-26
申请人： Dan W. Verser , Timothy J. Eggeman
发明人： Dan W. Verser , Timothy J. Eggeman
IPC分类号： C12P7/62 , C12P7/06
CPC分类号： C12P7/06 , B01D3/002 , C07C29/149 , C12P7/14 , C12P7/54 , C12P7/62 , Y02E50/16 , Y02E50/17 , Y02P20/127 , C07C31/08
摘要： A process for producing ethanol by the conversion of carbohydrates from a corn dry milling process in which the bottoms fraction from distillation of ethanol in a conventional yeast fermentation is used in a process including a combination of biochemical and synthetic conversions. The process results in high yield ethanol production with concurrent production of high value coproducts. An acetic acid intermediate is produced from bottoms fraction, followed by conversion of the acetic acid into ethanol using esterification and hydrogenation reactions. Coproducts of the process include a high protein content solids fraction produced in the fermentation.
摘要翻译：通过转化来自玉米干磨法的碳水化合物生产乙醇的方法，其中在常规酵母发酵中从蒸馏乙醇的塔底馏分用于包括生化和合成转化的组合的方法中。该方法产生高产乙醇生产，同时生产高价值的副产物。由塔底馏分产生乙酸中间体，然后使用酯化和氢化反应将乙酸转化成乙醇。该方法的副产物包括在发酵中产生的高蛋白质含量的固体含量。

170. 发明申请

US20110027837A1 PROCESSING BIOMASS 有权
标题翻译：加工生物量
公开(公告)号：US20110027837A1
公开(公告)日：2011-02-03
申请号：US12903430
申请日：2010-10-13
申请人： Marshall MEDOFF
发明人： Marshall MEDOFF
IPC分类号： C12P19/00 , C12P7/02 , C12P19/14
CPC分类号： D21B1/10 , C08H8/00 , C08L1/02 , C08L97/02 , C10G1/00 , C10G3/00 , C10G15/00 , C10G32/00 , C10G49/12 , C10G2300/1014 , C10L1/02 , C10L5/44 , C10L2200/0469 , C10L2250/04 , C10L2290/26 , C10L2290/36 , C12M21/04 , C12M21/12 , C12M45/00 , C12M45/02 , C12M45/20 , C12N9/2405 , C12P3/00 , C12P5/00 , C12P7/02 , C12P7/04 , C12P7/10 , C12P7/14 , C12P7/16 , C12P19/02 , C12P19/14 , C12P2201/00 , C12P2203/00 , D21H11/08 , F01K7/16 , F01K9/00 , F01K13/02 , F22B1/00 , Y02E50/10 , Y02E50/14 , Y02E50/16 , Y02E50/17 , Y02E50/30 , Y02E50/32 , Y02E50/343 , Y02P30/20 , C08L2666/02
摘要： Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to produce ethanol and/or butanol, e.g., by fermentation.
摘要翻译：加工生物质（例如，植物生物量，动物生物质和城市废物生物质）以产生有用的产物，例如燃料。例如，描述了可以使用原料如纤维素和/或木质纤维素材料来生产乙醇和/或丁醇的系统，例如通过发酵。

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