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121. 发明申请

US20080300660A1 Power generation for implantable devices 有权
标题翻译：用于植入式装置的发电
公开(公告)号：US20080300660A1
公开(公告)日：2008-12-04
申请号：US12131910
申请日：2008-06-02
申请人： Michael Sasha John
发明人： Michael Sasha John
IPC分类号： A61N1/378
CPC分类号： H02J7/025 , A61N1/37223 , A61N1/37252 , A61N1/3785 , A61N1/3787 , H02J5/005 , H02J50/10 , H02J50/20 , H02J50/50 , H02J50/70 , H02J50/80 , H04B1/40 , H04B5/0037 , H04B5/0062
摘要： An implantable, rechargeable medical system comprised of an implanted device, a power storage device connected to the implantable device, and a charging device operatively connected to the electrical storage device. The charging device can be thermoelectric and have components for transferring thermal energy from an intracranial heat accumulator to an extra-cranial heat sink, for generating an electrical current from the thermal energy transfer, for charging the electrical storage device using the electrical current, for measuring power generation, usage and reserve levels, for measuring temperatures of the intracranial and extra-cranial components, for physically disrupting heat transfer and charging operations, and for generating signals relevant to the status of temperature and electricity transfer in relation to energy generation criteria. The system may also have long-range and short range wireless power harvesting capability as well as movement, and photovoltaic charging capability. Components may be dual purpose, being used for receiving wireless energy as well as for accomplishing other operations such as sensing or stimulating. Specialized accessories assist with providing enhanced wireless power charging.
摘要翻译：一种可植入的可再充电医疗系统，包括植入装置，连接到可植入装置的蓄电装置以及可操作地连接到蓄电装置的充电装置。充电装置可以是热电，并且具有用于将热能从颅内蓄热器传递到颅外散热器的部件，用于从热能传递产生电流，用于使用电流对蓄电装置充电，用于测量发电，使用和储备水平，用于测量颅内和颅外部件的温度，用于物理中断热传递和充电操作，并产生与能量产生标准相关的温度和电力传输状态相关的信号。该系统还可以具有远距离和短距离的无线功率收集能力以及运动和光伏充电能力。组件可以是双重目的的，用于接收无线能量以及用于完成诸如感测或刺激之类的其他操作。专业配件有助于增强无线充电功能。

122. 发明申请

US20070213626A1 Baseline correction in systems for detecting ischemia 审中-公开
标题翻译：检测缺血系统的基线校正
公开(公告)号：US20070213626A1
公开(公告)日：2007-09-13
申请号：US11517382
申请日：2006-09-08
申请人： Michael Sasha John , Bruce Hopenfeld , David R. Fischell
发明人： Michael Sasha John , Bruce Hopenfeld , David R. Fischell
IPC分类号： A61B5/04
CPC分类号： A61B5/0452 , A61B5/0031 , A61B5/0428 , A61N1/3704
摘要： The present invention is a system that utilizes different filtering techniques to provide accurate detection of changes in the ST segment of an electrogram as detected by an implanted cardiosaver system, which ST segment changes are indicative of coronary ischemia. To accurately detect changes in the ST segment of the electrogram, the cardiosaver system partitions electrograms into different partition series, preferably including the QRS and ST segments, respectively. These partition series are then passed through different analog or digital high pass filters. An alternate embodiment involves low pass filtering the electrogram and then subtracting off the filtered signal, which represents baseline wander, from the electrogram. The system also includes both implanted and external portions that provide a patient alarm if coronary ischemia is sensed.
摘要翻译：本发明是利用不同的滤波技术来精确地检测由植入式心血管系统检测到的电描记图的ST段的变化的系统，其中ST段改变指示冠状动脉缺血。为了准确检测电描记图ST段的变化，心脏检查系统将电描绘图分成不同的分区序列，分别优选包括QRS和ST段。然后将这些分区系列通过不同的模拟或数字高通滤波器。替代实施例涉及对电描记图的低通滤波，然后从电描记图中减去表示基线漂移的滤波信号。该系统还包括植入和外部部分，如果感测到冠状动脉缺血则提供患者报警。

123. 发明授权

US06602202B2 System and methods for objective evaluation of hearing using auditory steady-state responses 有权
标题翻译：使用听觉稳态响应进行听觉客观评价的系统和方法
公开(公告)号：US06602202B2
公开(公告)日：2003-08-05
申请号：US09859637
申请日：2001-05-18
申请人： Michael Sasha John , Terence W. Picton
发明人： Michael Sasha John , Terence W. Picton
IPC分类号： A61B504
CPC分类号： A61B5/121 , A61B5/0051 , A61B5/04845 , A61B5/7257 , H04R25/70
摘要： This invention relates to an apparatus and method for assessing a subject's hearing by recording steady-state auditory evoked responses. The apparatus generates a steady-state auditory evoked potential stimulus, presents the stimulus to the subject, senses potentials while simultaneously presenting the stimulus and determines whether the sensed potentials contain responses to the stimulus. The stimulus may include an optimum vector combined amplitude modulation and frequency modulation signal adjusted to evoke responses with increased amplitudes, an independent amplitude modulation and frequency modulation signal and a signal whose envelope is modulated by an exponential modulation signal. The apparatus is also adapted to reduce noise in the sensed potentials by employing sample weighted averaging. The apparatus is also adapted to detect responses in the sensed potentials via the Phase weighted T-test or Phase zone technique. The apparatus may further perform a number of objective audiological tests including latency tests, AM/FM discrimination tests, rate sensitivity tests, aided hearing tests, depth sensitivity tests, supra-threshold tests and auditory threshold tests. The apparatus is further adapted to perform multi-modality testing in which more than one sensory modality of the subject is tested simultaneously.
摘要翻译：本发明涉及一种通过记录稳态听觉诱发反应来评估受试者的听力的装置和方法。该装置产生稳态听觉诱发电位刺激，向对象呈现刺激，同时呈现刺激并确定感测到的电位是否包含对刺激的响应。刺激可以包括调整为用于增加振幅的响应的调整的最佳矢量组合振幅调制和调制信号，独立的幅度调制和频率调制信号以及由指数调制信号调制其包络的信号。该装置还适于通过采用加权平均来减小感测电位中的噪声。该装置还适于经由相位加权T检验或相位区技术检测感测电位中的响应。该装置可以进一步执行多个客观的听力学测试，包括延迟测试，AM / FM鉴别测试，速率灵敏度测试，辅助听力测试，深度灵敏度测试，超阈值测试和听觉阈值测试。该装置还适于执行多模态测试，其中同时测试受试者的多于一种感觉模态。

124. 发明授权

US06385486B1 Brain function scan system 有权
标题翻译：脑功能扫描系统
公开(公告)号：US06385486B1
公开(公告)日：2002-05-07
申请号：US09447369
申请日：1999-11-23
申请人： Erwin Roy John , Michael Sasha John
发明人： Erwin Roy John , Michael Sasha John
IPC分类号： A61F700
CPC分类号： A61B5/0476 , A61B5/0002 , A61B5/0006 , A61B5/0484 , A61B5/407 , A61B5/4076 , A61B5/7257
摘要： A portable EEG (electroencephalograph) instrument, especially for use in emergencies and brain assessments in physicians' offices, detects and amplifies brain waves and converts them into digital data for analysis by comparison with data from normal groups. In one embodiment, the EEG electrodes are in a headband which broadcasts the data, by radio or cellular phone, to a local receiver for re-transmission and/or analysis. In another embodiment, the subject is stimulated in two modes, i.e., aural and sensory, at two different frequencies to provide the subject's EPs (Evoked Potentials), assessing transmission through the brainstem and thalamus.
摘要翻译：一种便携式EEG（脑电图仪），特别适用于医生办公室的紧急情况和脑部评估，可以检测和放大脑波，并将其转换为数字数据进行分析，与正常组数据进行比较。在一个实施例中，EEG电极处于通过无线电或蜂窝电话将数据广播到本地接收机以进行重新传输和/或分析的头带中。在另一个实施方案中，以两种不同的频率以两种模式（即听觉和感觉）刺激受试者，以提供受试者的EP（诱发电位），评估通过脑干和丘脑的传播。

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