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121. 发明申请

US20200214822A1 IMPLANTABLE DEVICE 审中-公开
公开(公告)号：US20200214822A1
公开(公告)日：2020-07-09
申请号：US16648801
申请日：2018-09-20
申请人： LIFETECH SCIENTIFIC (SHENZHEN) CO., LTD
发明人： Zhenjian LIN , Jun HU , Hongtao SUN , LI QIN , Deyuan ZHANG
IPC分类号： A61F2/04 , A61L31/10 , A61L31/14
摘要： An implantable device including a matrix and a zinc-containing layer at least partially covering the substrate. The zinc-containing layer includes a zinc compound. The ratio of the mass of the zinc element in the zinc-containing layer to the surface area of the implantable device is 0.1-200 μg/mm2. The average porosity of the zinc-containing layer is 30% or less. By matching the ratio of the mass of zinc in the zinc-containing layer to the surface area of the implantable device with the average porosity of the zinc-containing layer, the release rate of zinc is controlled within a reasonable range so that the rate of formation of the zinc-containing substance is controlled such that the concentration of the zinc-containing substance accumulated in the tissue is higher than the concentration which inhibits the proliferation of smooth muscle cells, and is always lower than the toxic concentration which causes cell death.

122. 发明申请

US20200214714A1 Left Atrial Appendage Occluder 审中-公开
公开(公告)号：US20200214714A1
公开(公告)日：2020-07-09
申请号：US16823718
申请日：2020-03-19
申请人： Lifetech Scientific (Shenzhen) Co., Ltd.
发明人： Anning Li , Zhuo Chen
IPC分类号： A61B17/12 , A61B17/00
摘要： A left atrial appendage occluder (200) comprises a sealing part (220), a fixing part (210) disposed at one side of the sealing part (220), and a connection part (230) for connecting the sealing part (220) and the fixing part (210). The radial deformation capacity of the sealing part (220) is greater than the radial deformation capacity of the fixing part (210), and/or, the axial deformation capacity of the sealing part (220) is greater than the axial deformation capacity of the fixing part (210). In the left atrial appendage occluder (200), the radial or axial deformation capacity of the sealing part (220) is configured to be greater than the radial or axial deformation capacity of the fixing part (210), thereby avoiding the situation in which the sealing part (220) is not optimally fitted with the opening of the left atrial appendage (10) when the fixing part (210) is placed inside of the left atrial appendage (10), which in turn enhances the occlusion effect. Additionally, the sealing part (220) has great deformation capacity which reduces the risks of the sealing part (220) causing abrasion to the opening of the left atrial appendage, or even damaging the opening of the left atrial appendage. The fixing part (210) not only avoids the risks, but also fixes the occluder in the left atrial appendage (10) more effectively, and prevents the occluder (200) from being disengaged from the left atrial appendage.

123. 发明申请

US20190381210A1 ABSORBABLE IRON-BASED DEVICE 审中-公开
公开(公告)号：US20190381210A1
公开(公告)日：2019-12-19
申请号：US16473722
申请日：2017-12-19
申请人： LIFETECH SCIENTIFIC (SHENZHEN) CO., LTD
发明人： Jun HU , Deyuan ZHANG , Hongtao SUN , Liping CHEN
IPC分类号： A61L27/04 , A61L27/58 , A61L31/02 , A61L27/34
摘要： An absorbable iron-based device includes an iron-based matrix and degradable polyester in contact with the surface of the iron-based matrix. The mass fraction of a low-molecular-weight part of the degradable polyester is less than or equal to 5%, and the molecular weight of the low-molecular-weight part is less than 10,000; or the mass fraction of a residual monomer in the degradable polyester is less than or equal to 2%.

124. 发明申请

US20190223882A1 Left Atrial Appendage Occluder 审中-公开
公开(公告)号：US20190223882A1
公开(公告)日：2019-07-25
申请号：US16373268
申请日：2019-04-02
申请人： Lifetech Scientific (Shenzhen) Co., Ltd.
发明人： Anning Li , Deyuan Zhang
IPC分类号： A61B17/12
摘要： A left atrial appendage occluder comprises an elastic closure disc, and a supporting structure connecting with the closure disc and being located on one side of the closure disc, with the supporting structure comprising a central end connecting with the closure disc and a plurality of interconnected and bent struts, wherein at least one anchoring thorn is set near the end of at least one strut with the anchoring thorn toward the closure disc. The left atrial appendage occluder has a stable structure, a good positioning and sealing effect on the cavity wall in the left atrial appendage, and it is easy to position repeatedly; it can also be recycled before separating from a conveyor. When in surgical operation, the left atrial appendage occluder can select the position area based on the actual shape and size of the patient's left atrial appendage, so the surgical risk is lowered.

125. 发明申请

US20190183643A1 DELIVERY DEVICE 审中-公开
公开(公告)号：US20190183643A1
公开(公告)日：2019-06-20
申请号：US16311282
申请日：2017-05-10
申请人： LIFETECH SCIENTIFIC (SHENZHEN) CO., LTD
发明人： Bin YAO , Xiangdong LIU
IPC分类号： A61F2/24
摘要： A delivery device used for delivering a heart valve, a blood vessel stent, and the like. The device includes a first stopper and a connecting unit. The connecting unit is provided opposite to the first stopper and can move relative to the first stopper. The connecting unit includes an axial connecting portion and at least two axial shafts. The axial shaft is connected to the connecting portion and faces the first stopper. The connecting unit is used to form, together with the first stopper, an enclosed and locked space.

126. 发明授权

US10251763B2 Braided self-expanding endoluminal stent and manufacturing method thereof 有权
公开(公告)号：US10251763B2
公开(公告)日：2019-04-09
申请号：US14441221
申请日：2013-11-06
申请人： Lifetech Scientific (Shenzhen) Co., Ltd.
发明人： Yongsheng Wang
IPC分类号： A61F2/89 , A61F2/90 , D04C1/06 , A61F2/86
摘要： A braided self-expandable endoluminal stent comprises a tubular grid formed by connection of a plurality of wave bends in the circumferential direction. Each of the wave bands comprises a plurality of crests and troughs of an elastic wire in the axial direction, and is respectively connected with another wave band. On two sides of each of the wave bands, there is a wave band abutted thereto side by side. There is at least one cross-linking point between every two wave bands abutted side by side. Each of the cross-linking points is formed by intersecting one trough on one of the wave bands abutted side by side with one corresponding crest on the other wave band, and at least one part of the cross-linking points are fixed cross-linking points. Each of the wave bands is further staggered and overlapped with at least another wave band, and a plurality of crossing points (12, 14, 22, 23) are formed between the wave bands which are staggered and overlapped with each other. Each of the wave bands, together with at least another wave band, forms a group of parallel wave bands. As the wave bands in this group are similar in wave shape and in parallel to each other, no cross-linking points or crossing points (12, 14, 22, 23) will be formed between the parallel wave bands.

127. 发明申请

US20190008996A1 Implanted Device 审中-公开
公开(公告)号：US20190008996A1
公开(公告)日：2019-01-10
申请号：US16068122
申请日：2016-06-27
申请人： Lifetech Scientific (Shenzhen) Co., Ltd.
发明人： Deyuan Zhang , Liping Chen , Haiping Qi , Hongtao Sun , Jun Hu , Wenjiao Lin
IPC分类号： A61L27/04 , A61L27/58 , A61L31/02 , A61L31/14 , A61L27/42 , A61K45/06 , A61P37/08 , A61P29/00 , A61F2/82 , C22C18/00 , C07F3/06
摘要： Disclosed is an implanted device, comprising a device base body and an active drug, wherein the device base body is pure zinc and/or a zinc alloy, the zinc content in the device base body is 0.1-100%, and the active drug comprises anti-allergic drugs. After the implantation of the implanted device into the human body, the surrounding tissues of the implant would not have a clear hypersensitive reaction due to the presence of the anti-allergic drugs, and the implanted device can be used to be implanted into the body for supporting organ chambers, to fill the hollow chambers of the organs and tissues or as orthopaedic implants etc.

128. 发明申请

US20190008994A1 IRON-BASED ABSORBABLE AND IMPLANTABLE MEDICAL DEVICE AND MANUFACTURING METHOD THEREOF 审中-公开
公开(公告)号：US20190008994A1
公开(公告)日：2019-01-10
申请号：US15737873
申请日：2016-06-01
申请人： Lifetech Scientific (Shenzhen) Co., Ltd.
发明人： Li QIN , Deyuan ZHANG , Wenjiao LIN , Haiping QI , Ziqiang LIU
IPC分类号： A61L27/04 , A61L31/16 , A61L31/12 , A61L27/58 , A61L27/54 , A61L31/14
摘要： Provided are an iron-based absorbable and implantable medical device and manufacturing method thereof. The iron-based absorbable and implantable medical device (1) comprises a substrate (11), a degradable polymer layer (12), and an anionic surfactant layer (13) located between the substrate (11) and the degradable polymer layer (12). The anionic surfactant, by using the hydrophobicity thereof, can form a hydrophobic barrier layer in a solution to isolate a surface of the iron-based substrate (11) from a body fluid environment, thereby avoiding direct contact with an acidic environment resulting from degradation of the degradable polymer layer (12) at the initial and early stages of implantation, thus preventing severe local corrosion of the iron-based substrate (11).

129. 发明授权

US10058636B2 Drug coated balloon catheter 有权
公开(公告)号：US10058636B2
公开(公告)日：2018-08-28
申请号：US15107806
申请日：2014-12-08
申请人： Lifetech Scientific (Shenzhen) Co., Ltd.
发明人： Qizong Xie , Yongmu Zhang , Jinhua Lu , Jingzhong Song
IPC分类号： A61L29/16 , A61L29/06 , A61L29/14 , A61M25/10
CPC分类号： A61L29/16 , A61L29/06 , A61L29/14 , A61L2300/416 , A61M25/10 , A61M2025/105 , C08L67/02 , C08L77/00 , C08L23/06
摘要： A drug coated balloon catheter has a balloon and a drug coating covering the surface of the balloon; the drug coating comprises an active drug and a carrier; the active drug is paclitaxel, rapamycin, a paclitaxel derivative or rapamycin derivative; the carrier comprises an organic acid salt and polyalcohol; a mass ratio of the active drug to the carrier in the drug coating is 0.2 to 100, and a mass ratio of the organic acid salt to the polyalcohol is (0.2 to 5):1. The organic acid salt and the polyalcohol in the drug coating jointly take effect to prevent the premature release of drugs before the balloon catheter is positioned at a target site, and to promote the drugs being quickly released from the surface of the balloon and absorbed by the target tissue, thus reducing drug loss during transmission, and also having a better drug transfer effect.

130. 发明申请

US20180214159A1 Absorbable Occluder 审中-公开
公开(公告)号：US20180214159A1
公开(公告)日：2018-08-02
申请号：US15741679
申请日：2016-06-07
申请人： Lifetech Scientific (Shenzhen) Co., Ltd.
发明人： Deyuan ZHANG , Dong XIANG , Xianmiao CHEN
IPC分类号： A61B17/12
摘要： An absorbable occluder (100) comprises a woven mesh (110), wherein the woven mesh (110) comprises at least two polymer filaments with different centralized degradation time periods, or comprises a polymer filament made by blending at least two polymers with different centralized degradation time periods. The absorbable occluder (100) can avoid the tissue inflammatory response caused by the polymer filaments of the woven mesh (110) centralized degrading within the same period.

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