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    • 111. 发明授权
    • Centrifuge assembly
    • 离心机总成
    • US5217427A
    • 1993-06-08
    • US771729
    • 1991-10-04
    • Herbert M. Cullis
    • Herbert M. Cullis
    • B04B1/00B04B5/04C07K16/06C07K16/30F04B9/02F04B43/10
    • C07K16/06B04B1/00B04B5/0428B04B5/0442C07K16/30F04B43/10F04B9/02B04B2005/045B04B2005/0464
    • A blood component separating device comprises a centrifuge bowl adapted for rotation about its axis in a centrifuge. The bowl defines an outer arcuate wall plus an inner circumferential wall, spaced from the outer wall, to define a arcuate slot adapted for receiving blood components. Access tubing is adapted for communication with the slot. Preferably, an elongated, flexible, collapsible inner liner is provided in the slot. Individual access tubing also may communicate with an elongated container interior between the ends of the elongated, collapsible container. Furthermore, a portion of the slot may define the shape of an outwardly extending spiral, to provide an increasing gravitational field upon fluids therein as the fluid moves along the slot.
    • 血液成分分离装置包括适于在离心机中围绕其轴旋转的离心机碗。 碗定义了外弧形壁加上与外壁间隔开的内周壁,以限定适于接收血液成分的弧形槽。 接入管适用于与槽连通。 优选地,在狭槽中设置细长的,柔性的可折叠内衬。 单独的进入管也可以与细长的可收缩容器的端部之间的细长的容器内部连通。 此外,槽的一部分可以限定向外延伸的螺旋的形状,以在流体沿着狭槽移动时为其中的流体提供增加的重力场。
    • 113. 发明授权
    • Centrifugal separator
    • 离心分离器
    • US4983156A
    • 1991-01-08
    • US374700
    • 1989-07-03
    • Benjamin Knelson
    • Benjamin Knelson
    • B04B1/00B04B7/08
    • B04B7/08B04B1/00
    • A centrifugal separator for extracting heavy metals from a slurry comprises a centrifuge bowl having an inwardly facing surface over which the slurry runs. A dam at a discharge end of the surface forms a shallow layer of particles which separate preferentially the heavy metals. The surface includes a portion formed by a plurality of annular membrane portions spaced axially and separated by radial rings extending from the surface to a supporting metal bowl. The membranes are deflated or retracted to gradually form annular cups for receiving the separated metals. The membranes are then inflated to discharge the collected materials while the feed is temporarily halted and the bowl continues to rotate.
    • 用于从浆料中提取重金属的离心分离器包括离心机碗,其具有向内的表面,浆料在其上运行。 表面排出端的坝形成了较浅分离的重金属颗粒层。 表面包括由轴向间隔开并由从表面延伸到支撑金属碗的径向环分隔开的多个环形膜部分形成的部分。 膜被放气或收缩以逐渐形成用于接收分离的金属的环形杯。 然后将膜膨胀以排出收集的材料,同时进料暂时停止并且碗继续旋转。
    • 114. 发明授权
    • Clarifying filter-centrifuge and method of filtering suspensions
    • 澄清过滤离心机和过滤悬浮液的方法
    • US4915851A
    • 1990-04-10
    • US237996
    • 1988-08-29
    • Wilfried Flory
    • Wilfried Flory
    • B04B1/02B04B1/00B04B3/00B04B3/02B04B7/16B04B11/04
    • B04B1/00B04B3/02
    • A clarifying filter-centrifuge comprises a rotatable driving shaft, a closed drum driven by the shaft, a cover which closes the drum at an end face thereof, and a filter diaphragm mounted in the cover and extending normal to an axis of rotation of the shaft. The drum includes an outer sleeve and an inner sleeve coaxial with the outer sleeve and having a thrust body. The driving shaft includes a hollow shaft and an inner shaft axially displaceable in the hollow shaft. The drum is connected to the hollow shaft. Suspension is fed axially into the inner sleeve and flows through distributing channels into the interior of the outer sleeve and then through the filter diaphragm. The cover is displaceable for discharging separated solids from the centrifuge.
    • 澄清过滤器 - 离心机包括可旋转的驱动轴,由轴驱动的封闭鼓,在其端面封闭鼓的盖,以及安装在盖中并垂直于轴的旋转轴线延伸的过滤膜 。 鼓包括外套筒和与外套管同轴并具有推力体的内套筒。 驱动轴包括中空轴和在中空轴中可轴向移动的内轴。 滚筒连接到空心轴。 悬架被轴向地供给到内套筒中,并且通过分配通道流入外套筒的内部,然后通过过滤隔膜。 盖子可移位以从离心机排出分离的固体。
    • 116. 发明授权
    • Specimen processing system
    • 标本处理系统
    • US4812294A
    • 1989-03-14
    • US20530
    • 1987-03-02
    • John W. Combs
    • John W. Combs
    • B01L3/00B04B5/02G01N1/28G01N35/00G01N21/00B04B1/00
    • B01L3/502B04B5/02G01N1/28B01L2200/0621B01L2400/0409B01L2400/0622B01L2400/0644G01N2035/00336Y10T436/111666
    • A specimen preparation unit having a plurality of interconnected compartments is automatically loaded onto a centrifuge rotor arm at a first rotor position. Each rotor arm has two indexing means for independently rotating the unit about either or both of two axes orthogonal to each other and to the rotor arm. The orientation of the unit with respect to the centrifugal force vector is changed in a predetermined manner so as to cause fluid flow between desired compartments even under conditions of microgravity. The unit is centrifuged in at least two different orientations with respect to the centrifugal force vector. As the fluids move between compartments, the specimen is prepared. After the multistep preparation process is completed, the unit is rotated to another rotor position at which the prepared specimen and/or the entire unit is removed. The centrifugal processing unit is capable of processing a plurality of specimen preparation unit in the same or a different manner. A plurality of the compartments of the specimen preparation unit are connected by force-sensitive valves which prevent reflux and which respond only to forces substantially exceeding gravity. The specimen preparation unit may provide for parallel processing of specimen aliquots.
    • 具有多个互连隔间的样品制备单元在第一转子位置处自动加载到离心机转子臂上。 每个转子臂具有两个分度装置,用于相对于彼此正交的两个轴和转子臂之间的一个或两个轴独立地旋转该单元。 相对于离心力矢量的单位的取向以预定的方式改变,使得即使在微重力的条件下也使流体在所需隔室之间流动。 该单元相对于离心力矢量以至少两个不同的取向离心。 当流体在隔室之间移动时,准备样品。 在多步准备过程完成之后,将单元旋转到另一转子位置,在该转动位置,准备的样本和/或整个单元被移除。 离心处理单元能够以相同或不同的方式处理多个样品制备单元。 样品制备单元的多个隔室通过防止回流并且仅响应于基本上超过重力的力的强力敏感阀连接。 样品制备单元可以提供样品等分试样的并行处理。
    • 118. 发明授权
    • Closed hemapheresis system and method
    • 闭塞血液透析系统及方法
    • US4776964A
    • 1988-10-11
    • US644032
    • 1984-08-24
    • Donald W. SchoendorferWilliam F. McLaughlin
    • Donald W. SchoendorferWilliam F. McLaughlin
    • B01D63/16A61B5/15A61M1/02A61M1/34A61M1/36B01D21/26B01D43/00B04B1/00B04B1/02B04B1/12B04B5/00B04B5/04B04B9/04B04B11/00G01N33/48B01D13/00
    • B04B5/0442A61M1/262A61M1/3496A61M1/3693A61M1/3696B01D61/08B01D63/062B01D63/16B01D69/043B01D2315/02B04B2005/0464B04B2005/0471
    • A hemapheresis system and method in accordance with the invention comprises a stationary closed housing concentric about a central axis and a feed system that moves blood upwardly from the housing lower end toward an outlet port adjacent a substantially closed upper end. Within the stationary housing is a double walled rotor concentric with the housing and rotatable by magnetic means within the housing on sealed end bearings. The space between the rotor walls defines a centrifugation gap into which whole blood is passed and within which centrifugal separation takes place as the rotor is spun at a relatively low rate. Whole blood also seeks to flow upwardly in the space between the rotor and housing, but this path is arranged to have a substantially higher flow impedance, so that the preferential path is within the centrifugation gap. At the upper end of the rotor, lighter matter such as plasma rich in platelets passes continuously inwardly to a central lengthwise passageway leading to an outlet port coaxial with the central axis, while heavier central matter flows through apertures in the outer rotor wall to the upper outlet port. In one example the differential impedance is established by housing and rotor configurations which diverge outwardly with compound curvatures, and with the space between rotor and housing leading to a closed end. In another example the housing-rotor space is of restricted cross section and an opposing flow of compatible fluid is introduced in an intermediate region of the flow path.
    • 根据本发明的血液透析系统和方法包括围绕中心轴线同心的固定的封闭壳体和将血液从壳体下端向上移动到邻近基本封闭的上端的出口的进料系统。 在固定壳体内部是与壳体同心的双壁转子,并且可以通过壳体内的磁性装置在密封端轴承上旋转。 转子壁之间的空间限定了一个离心间隙,全血通过其中,离心分离发生在转子以相对低的速度旋转时。 全血也寻求在转子和壳体之间的空间中向上流动,但是该路径被布置成具有显着更高的流动阻抗,使得优先路径在离心间隙内。 在转子的上端,诸如富含血小板的等离子体的较浅的物质连续向内通向中心纵向通道,通向与中心轴线同轴的出口,而较重的中心物质则通过外转子壁中的孔流动到上部 出口口 在一个示例中,通过外壳和转子配置来建立差分阻抗,外壳和转子配置以复合曲率向外发散,并且转子和壳体之间的空间导致封闭端。 在另一示例中,壳体 - 转子空间具有限制的横截面,并且相对流体的相容流体被引入流动路径的中间区域。
    • 119. 发明授权
    • Water-oil separating system including centrifugal type separator and
flow controls therefor
    • 水分离系统包括离心式分离器和流量控制装置
    • US4687572A
    • 1987-08-18
    • US854169
    • 1986-04-21
    • Tadeusz Budzich
    • Tadeusz Budzich
    • B04B1/00B04B5/00B04B11/04B01D33/04
    • B04B1/00B04B11/04B04B5/005
    • A centrifugal filter separator system operable to separate from oil under pressure, contaminants and water. The centrifuged water port of the centrifugal filter separator of the system is coupled to a differential pressure responsive, sensor control, which automatically senses the presence of a layer of centrifuged water against the internal surface of the rotating drum of the centrifugal separator. The sensor control is coupled to a flow control circuit which in conjunction with the differential pressure sensor control causes automatic removal of an existing layer of centrifuged water from the rotating drum via the water exit port of the separator. When there is no adequate depth layer of centrifuged water on the inner surface of the rotating drum, the sensor control deactivates the water removal circuit, while the flow control circuit maintains a minimum generally constant flow of liquid from the water port of the separator for priming purposes. The flow control circuit is coupled to a pressurized gravity type separator in the system from which separated oil is returned back to the centrifugal filter separator. The gravity separator includes an inverse relief valve circuit for replenishing water evacuated from the gravity separator, with oil from the pressure port of the system pump.
    • 离心过滤器分离器系统,可操作以在压力,污染物和水分离油。 系统的离心式过滤分离器的离心水口与压差响应的传感器控制器相连,传感器控制器自动检测离心分离器的旋转鼓内表面上存在一层离心水。 传感器控制耦合到流量控制电路,其结合差压传感器控制导致经由分离器的出水端口从旋转的滚筒自动移除现有的离心水层。 当旋转鼓的内表面上没有足够的离心水深度时,传感器控制使排水回路失效,而流量控制回路保持来自分离器的水口的液体的最小流量恒定不变,用于起动 目的 流量控制回路耦合到系统中的加压重力型分离器,分离的油从该分离器返回到离心过滤器分离器。 重力分离器包括用于补充从重力分离器排出的水的来自系统泵的压力端口的油的反向安全阀回路。