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111. 发明授权

US09308042B2 Vacuum coagulation probes 有权
公开(公告)号：US09308042B2
公开(公告)日：2016-04-12
申请号：US13905696
申请日：2013-05-30
申请人： nContact Surgical, Inc.
发明人： James G. Whayne , Sidney D. Fleischman , Earl W. Rogers
IPC分类号： A61B18/14 , A61B18/18 , A61B18/00
CPC分类号： A61B18/1492 , A61B18/082 , A61B18/148 , A61B18/18 , A61B2018/00083 , A61B2018/0019 , A61B2018/00291 , A61B2018/00351 , A61B2018/00488 , A61B2018/00494 , A61B2018/00529 , A61B2018/00547 , A61B2018/00559 , A61B2018/00577 , A61B2018/00589 , A61B2018/1437 , A61B2018/1472 , A61B2018/1497 , A61B2218/002 , A61B2218/007
摘要： Methods for using a surgical device integrating a suction mechanism with a coagulation mechanism for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source and a fluid source to passively transport fluid along the contacted soft tissue surface in order to push the maximum temperature deeper into tissue.

112. 发明申请

US20160051465A1 CHEMICAL NEUROMODULATION OF NERVES INNERVATING THE LIVER 审中-公开
标题翻译：神经内分泌化学神经元
公开(公告)号：US20160051465A1
公开(公告)日：2016-02-25
申请号：US14832302
申请日：2015-08-21
申请人： Metavention, Inc.
发明人： Bobak Robert Azamian , Scott Bradley Vafai
IPC分类号： A61K9/00
CPC分类号： A61B18/02 , A61B17/00 , A61B17/00234 , A61B17/32 , A61B17/320068 , A61B18/04 , A61B18/06 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B18/20 , A61B18/24 , A61B2017/00318 , A61B2018/00023 , A61B2018/00214 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00529 , A61B2018/00577 , A61B2018/00732 , A61B2018/00791 , A61B2018/00839 , A61B2018/00994 , A61B2018/0212 , A61B2018/048 , A61B2018/1861 , A61K9/0019 , A61K31/045 , A61K31/05 , A61K31/395 , A61K33/30 , A61K45/06 , A61M5/14 , A61N1/0551 , A61N5/00 , A61N7/00 , A61N7/022
摘要： According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
摘要翻译：根据一些实施方案，提供了治疗患有糖尿病或与糖尿病相关的症状的受试者的方法。该方法包括在具有支配肝脏的周围神经（例如，肝神经的交感神经）的血管（例如，肝动脉）内递送神经调节导管。该方法还可以包括通过机械压缩，能量输送或流体输送调节（例如，破坏，消融，刺激）神经。

113. 发明申请

US20160022369A1 System And Method For Interactive Patient Specific Simulation Of Radiofrequency Ablation Therapy 审中-公开
标题翻译：射频消融治疗的交互式患者特异性模拟的系统和方法
公开(公告)号：US20160022369A1
公开(公告)日：2016-01-28
申请号：US14769844
申请日：2014-02-24
申请人： SIEMENS AKTIENGESELLSCHAFT
发明人： Chloe Audigier , Tommaso Mansi , Viorel Mihalef , Ali Kamen , Dorin Comaniciu , Puneet Sharma , Saikiran Rapaka
IPC分类号： A61B19/00 , G09B5/02 , G09B23/30
CPC分类号： G09B5/02 , A61B6/032 , A61B6/50 , A61B6/5217 , A61B34/10 , A61B2018/00404 , A61B2018/00529 , A61B2034/104 , A61B2034/105 , A61B2034/107 , G09B23/30 , G09B23/303 , G16H50/50
摘要： A method and system for interactive patient-specific simulation of liver tumor ablation is disclosed. A patient-specific anatomical model of the liver and circulatory system of the liver is estimated from 3D medical image data of a patient. A computational domain is generated from the patient-specific anatomical model of the liver. Blood flow in the liver and the circulatory system of the liver is simulated based on the patient-specific anatomical model. Heat diffusion due to ablation is simulated based on a virtual ablation probe position and the simulated blood flow in the liver and the circulatory system of the liver by solving a bio-heat equation for each node on the level-set representation using a Lattice-Boltzmann method (LBM) implementation. Cellular necrosis in the liver is computed based on the simulated heat diffusion. Visualizations of a computed necrosis region and temperature maps of the liver are generated. A user input is interactively received to modify the position of the virtual ablation probe, the heat diffusion and cellular necrosis is re-simulated based on the user input, and the visualizations of the computed necrosis region and the temperature maps are updated.
摘要翻译：公开了用于肝肿瘤消融的患者特异性模拟交互的方法和系统。根据患者的3D医学图像数据估计肝脏和肝脏循环系统的患者特异性解剖模型。从肝脏的患者特异性解剖模型中产生计算结构域。根据患者特异性解剖模型模拟肝脏和肝脏循环系统的血流。基于虚拟消融探针位置和肝脏和肝循环系统中的模拟血流模拟了消融引起的热扩散，通过使用莱迪思 - 玻尔兹曼（Lattice-Boltzmann）在水平仪表示上求解每个节点的生物热方程方法（LBM）实现。基于模拟的热扩散计算肝脏细胞坏死。产生计算坏死区域和肝脏温度图的可视化。交互地接收用户输入以修改虚拟消融探针的位置，基于用户输入重新模拟热扩散和细胞坏死，并且更新计算的坏死区域和温度图的可视化。

114. 发明授权

US09186214B2 Coaptive surgical sealing tool 有权
标题翻译：适应手术密封工具
公开(公告)号：US09186214B2
公开(公告)日：2015-11-17
申请号：US13842510
申请日：2013-03-15
申请人： CITY OF HOPE
发明人： Gagandeep Singh
IPC分类号： A61B18/18 , A61B18/14 , A61B18/00
CPC分类号： A61B18/1445 , A61B18/1442 , A61B18/18 , A61B2018/00345 , A61B2018/00404 , A61B2018/00529 , A61B2018/0063
摘要： A coaptive surgical sealing tool may be similar to an ordinary hemostat with long (50, 60, 70 or 80 mm) thin jaws for sliding into the liver parenchyma, without tearing the larger blood vessels. The jaws are spring loaded and are designed for uniform compression, and to avoid closing too quickly. The jaws are capable of sealing a 50, 60, 70 or 80 mm sealing length, in a single bite, although it can also seal shorter lengths as well. The tool can be used with existing RF/bi-polar cautery generators.
摘要翻译：合适的手术密封工具可以类似于具有长（50,60,70或80mm）薄爪的普通止血器，用于滑入肝实质，而不撕裂较大的血管。夹爪是弹簧加载的，设计用于均匀压缩，并避免关闭太快。钳口能够在单个咬合中密封50,60,70或80mm的密封长度，尽管它也可以密封较短的长度。该工具可用于现有的RF /双极烧焦发生器。

115. 发明授权

US09186197B2 Nerve and soft tissue ablation device for treating pain 有权
标题翻译：用于治疗疼痛的神经和软组织消融装置
公开(公告)号：US09186197B2
公开(公告)日：2015-11-17
申请号：US13835557
申请日：2013-03-15
申请人： Warsaw Orthopedic, Inc.
发明人： William F. McKay
IPC分类号： A61B18/02 , A61B18/00 , A61B19/00
CPC分类号： A61B18/02 , A61B2018/00351 , A61B2018/00434 , A61B2018/00529 , A61B2018/00541 , A61B2018/00565 , A61B2018/00577 , A61B2018/00821 , A61B2018/00875 , A61B2018/00886 , A61B2018/0262 , A61B2018/0293 , A61B2034/2051 , A61B2034/2055 , A61B2090/062 , A61B2090/064
摘要： Ablation kits useful for destroying nerve and soft tissue via a minimally invasive procedure to alleviate pain are provided. The device comprises a probe having an exterior and an interior. The exterior comprises a tip and the interior defines a passage having a filament and insulation disposed therein. The filament has an opening configured to release a pressurized material into the interior of the probe so as to cool the tip to a selected temperature to ablate nerve and/or soft tissue. A bone piercing instrument is provided that is configured to pierce bone so as to allow entry of the probe into the bone. Methods for ablating nerve and/or soft tissue utilizing the ablation devices are also provided.
摘要翻译：提供了用于通过微创手术来消除神经和软组织以减轻疼痛的消融装置。该装置包括具有外部和内部的探针。外部包括尖端，并且内部限定了具有细丝的通道和设置在其中的绝缘体。细丝具有被配置为将加压材料释放到探针内部的开口，以便将尖端冷却到选定的温度以消融神经和/或软组织。提供了一种骨穿刺器械，其被构造成刺穿骨头，以允许探针进入骨骼。还提供了利用消融装置消融神经和/或软组织的方法。

116. 发明授权

US09149329B2 Glucose alteration methods 有权
标题翻译：葡萄糖改变方法
公开(公告)号：US09149329B2
公开(公告)日：2015-10-06
申请号：US14076008
申请日：2013-11-08
申请人： METAVENTION, INC.
发明人： Bobak Robert Azamian , Jonathan Allen Coe , Scott Bradley Vafai
IPC分类号： A61B18/18 , A61B18/14 , A61B17/32 , A61N5/00 , A61B17/00 , A61B18/06 , A61N7/00 , A61B18/20 , A61M5/14 , A61K31/045 , A61K31/05 , A61K31/395 , A61K33/30 , A61K45/06 , A61N7/02 , A61B18/24 , A61B18/00 , A61B18/02 , A61B18/04
CPC分类号： A61B18/02 , A61B17/00 , A61B17/00234 , A61B17/32 , A61B17/320068 , A61B18/04 , A61B18/06 , A61B18/1492 , A61B18/18 , A61B18/1815 , A61B18/20 , A61B18/24 , A61B2017/00318 , A61B2018/00023 , A61B2018/00214 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00529 , A61B2018/00577 , A61B2018/00732 , A61B2018/00791 , A61B2018/00839 , A61B2018/00994 , A61B2018/0212 , A61B2018/048 , A61B2018/1861 , A61K9/0019 , A61K31/045 , A61K31/05 , A61K31/395 , A61K33/30 , A61K45/06 , A61M5/14 , A61N1/0551 , A61N5/00 , A61N7/00 , A61N7/022
摘要： According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
摘要翻译：根据一些实施方案，提供了治疗患有糖尿病或与糖尿病相关的症状的受试者的方法。该方法包括在具有支配肝脏的周围神经（例如，肝神经的交感神经）的血管（例如，肝动脉）内递送神经调节导管。该方法还可以包括通过机械压缩，能量输送或流体输送调节（例如，破坏，消融，刺激）神经。

117. 发明申请

US20150250540A1 MICROWAVE ABLATION ANTENNA SYSTEM 审中-公开
标题翻译：微波雷达天线系统
公开(公告)号：US20150250540A1
公开(公告)日：2015-09-10
申请号：US14202786
申请日：2014-03-10
申请人： Wisconsin Alumni Research Foundation
发明人： Nader Behdad , Susan C. Hagness , Hung Thanh Luyen
IPC分类号： A61B18/18 , H01Q1/50
CPC分类号： A61B18/1815 , A61B2018/00529 , A61B2018/00577 , A61B2018/1846 , A61B2018/1853 , A61B2018/1892 , H01Q9/42
摘要： An antenna system is provided. The antenna system includes a coaxial cable, an antenna, and an impedance matching structure. The coaxial cable includes a center conductor extending a length of the coaxial cable, a dielectric material surrounding the center conductor along the length of the coaxial cable, and a conductive shield surrounding the dielectric material along the length of the coaxial cable. The antenna includes a conductor having an electrical length of half a wavelength at a selected operating frequency. The impedance matching structure includes a second center conductor mounted between an end of the center conductor of the coaxial cable and a feed end of the antenna. The impedance matching structure is configured to match an impedance of the coaxial cable to an impedance of the antenna.
摘要翻译：提供天线系统。天线系统包括同轴电缆，天线和阻抗匹配结构。同轴电缆包括延伸同轴电缆长度的中心导体，沿同轴电缆的长度围绕中心导体的电介质材料，以及围绕同轴电缆长度的电介质材料的导电屏蔽。天线包括在所选择的工作频率下具有半波长的电长度的导体。阻抗匹配结构包括安装在同轴电缆的中心导体的端部与天线的馈电端之间的第二中心导体。阻抗匹配结构被配置为将同轴电缆的阻抗与天线的阻抗相匹配。

118. 发明授权

US09119650B2 Microwave energy-delivery device and system 有权
标题翻译：微波能量输送装置及系统
公开(公告)号：US09119650B2
公开(公告)日：2015-09-01
申请号：US13834581
申请日：2013-03-15
申请人： Covidien LP
发明人： Joseph D. Brannan , Casey M. Ladtkow , Darion R. Peterson , Eric W. Larson , William J. Dickhans , Richard A. Willyard , Jason A. Case
IPC分类号： A61B18/04 , A61B18/18 , A61B18/00
CPC分类号： A61B18/1815 , A61B34/10 , A61B34/25 , A61B2018/00017 , A61B2018/00023 , A61B2018/00166 , A61B2018/00178 , A61B2018/00297 , A61B2018/00482 , A61B2018/00494 , A61B2018/00511 , A61B2018/00529 , A61B2018/00541 , A61B2018/00577 , A61B2018/00678 , A61B2018/00684 , A61B2018/00702 , A61B2018/00708 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00982 , A61B2018/00988 , A61B2018/1823 , A61B2018/1838 , A61B2018/1846 , A61B2018/1853 , A61B2018/1861 , A61B2018/1892 , A61B2034/105 , A61B2034/107
摘要： A microwave ablation device including a cable assembly configured to connect a microwave ablation device to an energy source and a feedline in electrical communication with the cable assembly. The microwave ablation device further includes a balun on an outer conductor of the feedline, and a temperature sensor on the balun sensing the temperature of the balun.
摘要翻译：一种微波消融装置，包括被配置为将微波消融装置连接到能量源的电缆组件和与电缆组件电连通的馈线。微波消融装置还包括在馈线的外导体上的平衡 - 不平衡转换器，以及平衡 - 不平衡变换器上的温度传感器，感测平衡 - 不平衡转换器的温度。

119. 发明申请

US20150230856A1 DUAL-MODE ELECTROSURGICAL DEVICES AND ELECTROSURGICAL METHODS USING SAME 有权
标题翻译：双模式静电设备和使用该方法的电化学方法
公开(公告)号：US20150230856A1
公开(公告)日：2015-08-20
申请号：US14628427
申请日：2015-02-23
申请人： ElectroMedical Associates LLC
发明人： Robert A. VAN WYK , Yuval Carmel , Anatoly Shkvarunets
IPC分类号： A61B18/14
CPC分类号： A61B18/1402 , A61B2018/00327 , A61B2018/00333 , A61B2018/00529 , A61B2018/00601 , A61B2018/00607 , A61B2018/00625 , A61B2018/00958 , A61B2018/1412 , A61B2018/1472 , A61B2018/1475 , A61B2018/162 , A61B2018/167 , A61B2217/007 , A61B2218/002
摘要： Herein disclosed are dual-mode electrosurgical devices designed to function in a first mode in which high-density RF energy is used to cut or vaporize tissue, and then a second mode in which lower-density RF energy desiccates tissue to produce hemostasis, as well as methods of performing electrosurgery using same. Devices formed in accordance with the principles of this invention may be used for any surgical procedure in which highly vascular tissue is cut electrosurgically in a dry or semi-dry field, examples of which include tonsillectomy, liver resection, and cosmetic procedures such as breast augmentation, breast reduction, breast mastopexy, and abdominoplasty.
摘要翻译：本文公开的是设计为在其中使用高密度RF能量来切割或蒸发组织的第一模式中工作的双模电外科设备，然后是其中较低密度RF能量干燥组织以产生止血的第二模式作为使用其进行电外科手术的方法。根据本发明的原理形成的装置可用于在干或半干燥的场中电外切割高血管组织的任何外科手术，其实例包括扁桃体切除术，肝切除术和诸如隆胸术的美容方法，乳房减少，乳房乳腺炎和腹部成形术。

120. 发明申请

US20150230850A1 NERVE AND SOFT TISSUE ABLATION DEVICE HAVING RELEASE INSTRUMENT 有权
标题翻译：具有释放仪器的神经和软组织消除装置
公开(公告)号：US20150230850A1
公开(公告)日：2015-08-20
申请号：US14703199
申请日：2015-05-04
申请人： Warsaw Orthopedic, Inc.
发明人： William F. McKay
IPC分类号： A61B18/02 , A61B17/00
CPC分类号： A61B18/02 , A61B17/00234 , A61B18/0218 , A61B2018/00041 , A61B2018/00095 , A61B2018/00166 , A61B2018/00202 , A61B2018/00351 , A61B2018/00434 , A61B2018/00529 , A61B2018/00541 , A61B2018/00565 , A61B2018/00577 , A61B2018/00821 , A61B2018/00875 , A61B2018/0262 , A61B2018/0293 , A61B2034/2051 , A61B2034/2055 , A61B2090/062
摘要： Ablation devices useful tor destroying nerve and soft tissue via a minimally invasive procedure to alleviate pain are provided. The device comprises a probe comprising an ulterior surface, that defines an internal passage and an exterior surface comprising a tip. The internal passage has a filament comprising an opening configured to release a pressurized material into the interior surface of the probe so as to cool the exterior surface of the probe to a selected temperature. A release instrument is provided comprising a sheath that comprises an exterior surface and an interior surface configured for engagement with the probe. The probe tip is configured for ablating nerve and/or soft tissue by forming an ice ball, and the release instrument is configured to release the probe tip from the ice ball. Methods for ablating nerve and/or soft tissue utilizing the ablation devices are also provided.
摘要翻译：提供了通过微创手术来破坏神经和软组织以消除疼痛的消融装置。该装置包括探针，其包括限定内部通道的外表面和包括尖端的外表面。内部通道具有灯丝，其包括构造成将加压材料释放到探针的内表面中的开口，以便将探针的外表面冷却到所选择的温度。提供了一种释放器械，其包括护套，其包括外表面和构造成用于与探针接合的内表面。探针尖端被配置为通过形成冰球来消融神经和/或软组织，并且释放装置构造成从冰球释放探针尖端。还提供了利用消融装置消融神经和/或软组织的方法。

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