专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

111. 发明授权

US07687522B2 Substituted pyridines and pyrimidines and their use in treatment of cancer 有权
标题翻译：取代的吡啶和嘧啶及其在治疗癌症中的应用
公开(公告)号：US07687522B2
公开(公告)日：2010-03-30
申请号：US12004284
申请日：2007-12-19
申请人： Steven Bellon , Shon Booker , Noel D'Angelo , Ingrid M. Fellows , Jean-Christophe Harmange , Tae-Seong Kim , Matthew Lee , Longbin Liu , Mark H. Norman
发明人： Steven Bellon , Shon Booker , Noel D'Angelo , Ingrid M. Fellows , Jean-Christophe Harmange , Tae-Seong Kim , Matthew Lee , Longbin Liu , Mark H. Norman
IPC分类号： A61K31/44
CPC分类号： C07D401/14 , C07D401/12
摘要： Selected pyridine and pyrimidine compounds of Formula I are effective for prophylaxis and treatment of diseases, such as c-met mediated diseases and/or HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
摘要翻译：所选择的式I的吡啶和嘧啶化合物对预防和治疗诸如c-met介导的疾病和/或HGF介导的疾病的疾病是有效的。本发明包括新颖的化合物，类似物，前药和药学上可接受的盐，用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。

112. 发明授权

US07561486B2 Flash memory devices with flash fuse cell arrays 有权
标题翻译：带闪存保险丝单元阵列的闪存设备
公开(公告)号：US07561486B2
公开(公告)日：2009-07-14
申请号：US11346520
申请日：2006-02-02
申请人： Tae-Seong Kim , Gyu-Hong Kim
发明人： Tae-Seong Kim , Gyu-Hong Kim
IPC分类号： G11C17/18
CPC分类号： G11C29/021 , G11C16/04 , G11C16/0425 , G11C29/028 , G11C29/789 , G11C29/82
摘要： A flash memory device includes a flash cell array, a first flash fuse cell fusing circuit, a second flash fuse cell fusing circuit, a third flash fuse cell fusing circuit and a plurality of fuse sense amplifying circuits. The first, second and third flash fuse cell fusing circuits all share bit lines with a flash cell array and have flash fuse cells. The first flash fuse cell fusing circuit may be used to control a connection between the flash cell array and an external logic circuit. The second flash fuse cell fusing circuit may be used to change an address of a defective cell into an address of a redundancy cell. The third flash fuse cell fusing circuit may be used to control a DC level for adjusting a reference value used in a manufacturing process of the flash memory device. The fuse sense amplifying circuits are coupled to the bit lines to read data from the bit lines, respectively.
摘要翻译：闪存器件包括闪存单元阵列，第一闪存熔丝单元熔丝电路，第二闪存熔丝单元熔丝电路，第三闪存熔丝单元熔断电路和多个熔丝读出放大电路。第一，第二和第三闪存熔丝单元熔断电路都与闪存单元阵列共享位线并具有闪存熔丝单元。第一闪存熔丝单元熔断电路可用于控制闪存单元阵列和外部逻辑电路之间的连接。第二闪存熔丝单元熔断电路可用于将有缺陷单元的地址改变为冗余单元的地址。第三闪存熔丝单元熔断电路可以用于控制DC电平以调整在闪速存储器件的制造过程中使用的参考值。熔丝读出放大电路分别耦合到位线以从位线读取数据。

113. 发明授权

US07514564B2 Substituted amine derivatives and methods of use 失效
标题翻译：取代的胺衍生物和使用方法
公开(公告)号：US07514564B2
公开(公告)日：2009-04-07
申请号：US11417329
申请日：2006-05-02
申请人： Guoqing Chen , Jeffrey Adams , Jean Bemis , Lucian Di Pietro , Celia Dominguez , Daniel Elbaum , Julie Germain , Qi Huang , Joseph L. Kim , Xiaohu Ouyang , Vinod F. Patel , Leon M. Smith , Andrew Tasker , Ning Xi , Shimin Xu , Chester Chenguang Yuan , Michael Croghan , Tae-Seong Kim
发明人： Guoqing Chen , Jeffrey Adams , Jean Bemis , Lucian Di Pietro , Celia Dominguez , Daniel Elbaum , Julie Germain , Qi Huang , Joseph L. Kim , Xiaohu Ouyang , Vinod F. Patel , Leon M. Smith , Andrew Tasker , Ning Xi , Shimin Xu , Chester Chenguang Yuan , Michael Croghan , Tae-Seong Kim
IPC分类号： C07D211/94 , C07D211/98 , A61K31/44
CPC分类号： C07D401/14 , A61K31/00 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/14 , C07D471/04 , Y02A50/401
摘要： Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
摘要翻译：选择的胺对于预防和治疗疾病如血管生成介导的疾病是有效的。本发明包括新颖的化合物，类似物，前药和药学上可接受的盐，用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。

114. 发明申请

US20090054405A1 PI3 kinase modulators and methods of use 有权
标题翻译： PI3激酶调节剂和使用方法
公开(公告)号：US20090054405A1
公开(公告)日：2009-02-26
申请号：US12221416
申请日：2008-08-01
申请人： Shon Booker , Noel D'Angelo , Derin C. D'Amico , Tae-Seong Kim , Longbin Liu , Kristin Meagher , Mark H. Norman , Kathleen Panter , Laurie B. Schenkel , Adrian L. Smith , Nuria A. Tamayo , Douglas A. Whittington , Ning Xi , Kevin Yang
发明人： Shon Booker , Noel D'Angelo , Derin C. D'Amico , Tae-Seong Kim , Longbin Liu , Kristin Meagher , Mark H. Norman , Kathleen Panter , Laurie B. Schenkel , Adrian L. Smith , Nuria A. Tamayo , Douglas A. Whittington , Ning Xi , Kevin Yang
IPC分类号： A61K31/55 , C07D401/14 , C07D401/10 , C07D413/14 , A61P35/00 , A61K31/435 , A61K31/5377 , A61K31/497
CPC分类号： C07D277/82 , C07D413/04 , C07D417/04 , C07D417/14 , C07D513/04
摘要： The present invention comprises a new class of compounds capable of modulating the activity of PI3 kinase and, accordingly, useful for treatment of PI3 kinase mediated diseases, including melanomas, carcinomas and other cancer-related conditions. The compounds have a general Formula I wherein each of A1, A2, A3, A4, X, R1 and R2 are defined herein. The invention further comprises pharmaceutical compositions, methods for treatment of PI3 kinase mediated diseases, and intermediates and processes useful for the preparation of compounds of the invention.
摘要翻译：本发明包括能够调节PI3激酶活性的新一类化合物，因此可用于治疗PI3激酶介导的疾病，包括黑素瘤，癌和其它癌症相关病症。所述化合物具有通式I，其中A1，A2，A3，A4，X，R1和R2各自在本文中定义。本发明还包括药物组合物，治疗PI3激酶介导的疾病的方法，以及可用于制备本发明化合物的中间体和方法。

115. 发明申请

US20080280917A1 Nitrogen-Containing heterocyclyl ketones and methods of use 有权
标题翻译：含氮杂环基酮及其使用方法
公开(公告)号：US20080280917A1
公开(公告)日：2008-11-13
申请号：US12070309
申请日：2008-02-15
申请人： Brian K. Albrecht , Steven Bellon , Shon Booker , Alan C. Cheng , Derin D'Amico , Noel D'Angelo , Jean-Christophe Harmange , Tae-Seong Kim , Longbin Liu , Mark H. Norman , Aaron C. Siegmund , Markian Stec , Ning Xi , Kevin Yang
发明人： Brian K. Albrecht , Steven Bellon , Shon Booker , Alan C. Cheng , Derin D'Amico , Noel D'Angelo , Jean-Christophe Harmange , Tae-Seong Kim , Longbin Liu , Mark H. Norman , Aaron C. Siegmund , Markian Stec , Ning Xi , Kevin Yang
IPC分类号： A61K31/501 , C07D403/12 , A61K31/4709 , A61P25/00 , A61P35/00 , C07D471/00
CPC分类号： C07D237/16 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/14 , C07D471/04
摘要： Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
摘要翻译：所选化合物对于预防和治疗诸如HGF介导的疾病等疾病是有效的。本发明包括新颖的化合物，类似物，前药和药学上可接受的盐，用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。

116. 发明申请

US20070054903A1 Bis-aryl kinase inhibitors and method 有权
标题翻译：双芳基激酶抑制剂和方法
公开(公告)号：US20070054903A1
公开(公告)日：2007-03-08
申请号：US11479187
申请日：2006-06-30
申请人： Tae-Seong Kim , Jean-Christophe Harmange , Steven Bellon , Shon Booker , Noel D'Angelo , Celia Dominguez , Ingrid Fellows , Julie Germain , Timothy Harvey , Joseph Kim , Matthew Lee , Longbin Liu , Vinod Patel , Andrew Tasker
发明人： Tae-Seong Kim , Jean-Christophe Harmange , Steven Bellon , Shon Booker , Noel D'Angelo , Celia Dominguez , Ingrid Fellows , Julie Germain , Timothy Harvey , Joseph Kim , Matthew Lee , Longbin Liu , Vinod Patel , Andrew Tasker
IPC分类号： A61K31/538 , A61K31/5377 , A61K31/4709 , C07D403/02 , C07D413/02
CPC分类号： C07D333/38 , C07D217/02 , C07D217/24 , C07D401/10 , C07D401/12 , C07D409/12 , C07D417/10 , C07D417/12
摘要： Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
摘要翻译：所选化合物对于预防和治疗诸如HGF介导的疾病等疾病是有效的。本发明包括新颖的化合物，类似物，前药和药学上可接受的盐，用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。

117. 发明授权

US07102009B2 Substituted amine derivatives and methods of use 有权
公开(公告)号：US07102009B2
公开(公告)日：2006-09-05
申请号：US10197918
申请日：2002-07-17
申请人： Vinod F. Patel , Benny Askew , Shon Booker , Guoqing Chen , Lucian V. DiPietro , Julie Germain , Gregory J. Habgood , Qi Huang , Tae-Seong Kim , Aiwen Li , Nobuko Nishimura , Rana Nomak , Babak Riahi , Chester Chenguang Yuan , Daniel Elbaum
发明人： Vinod F. Patel , Benny Askew , Shon Booker , Guoqing Chen , Lucian V. DiPietro , Julie Germain , Gregory J. Habgood , Qi Huang , Tae-Seong Kim , Aiwen Li , Nobuko Nishimura , Rana Nomak , Babak Riahi , Chester Chenguang Yuan , Daniel Elbaum
IPC分类号： C07D401/02 , A61K31/44
CPC分类号： C07D471/04 , A61K31/00 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/14
摘要： Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

118. 发明授权

US07101868B2 Substituted arylamine derivatives and methods of use 有权
公开(公告)号：US07101868B2
公开(公告)日：2006-09-05
申请号：US10823809
申请日：2004-04-12
申请人： Daniel Elbaum , Benny C. Askew, Jr. , Shon Booker , Julie Germain , Gregory J. Habgood , Michael Handley , Tae-Seong Kim , Aiwen Li , Nobuko Nishimura , Vinod F. Patel , Chester Chenguang Yuan , Joseph L. Kim , Guolin Cai , Guoqing Chen , Michael Croghan , Lucian V. Di Pietro , Celia Dominguez , Qi Huang , Leon M. Smith, II , Andrew Tasker , Ning Xi , Shimin Xu
发明人： Daniel Elbaum , Benny C. Askew, Jr. , Shon Booker , Julie Germain , Gregory J. Habgood , Michael Handley , Tae-Seong Kim , Aiwen Li , Nobuko Nishimura , Vinod F. Patel , Chester Chenguang Yuan , Joseph L. Kim , Guolin Cai , Guoqing Chen , Michael Croghan , Lucian V. Di Pietro , Celia Dominguez , Qi Huang , Leon M. Smith, II , Andrew Tasker , Ning Xi , Shimin Xu
IPC分类号： A61K31/33 , A61K31/44 , C07D211/62 , C07D213/72
CPC分类号： C07D213/81 , C04B35/632 , C07D213/82 , C07D237/04 , C07D237/24 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04
摘要： Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

119. 发明申请

US20060176740A1 Flash memory devices with flash fuse cell arrays 有权
公开(公告)号：US20060176740A1
公开(公告)日：2006-08-10
申请号：US11346520
申请日：2006-02-02
申请人： Tae-Seong Kim , Gyu-Hong Kim
发明人： Tae-Seong Kim , Gyu-Hong Kim
IPC分类号： G11C16/04
CPC分类号： G11C29/021 , G11C16/04 , G11C16/0425 , G11C29/028 , G11C29/789 , G11C29/82
摘要： A flash memory device includes a flash cell array, a first flash fuse cell fusing circuit, a second flash fuse cell fusing circuit, a third flash fuse cell fusing circuit and a plurality of fuse sense amplifying circuits. The first, second and third flash fuse cell fusing circuits all share bit lines with a flash cell array and have flash fuse cells. The first flash fuse cell fusing circuit may be used to control a connection between the flash cell array and an external logic circuit. The second flash fuse cell fusing circuit may be used to change an address of a defective cell into an address of a redundancy cell. The third flash fuse cell fusing circuit may be used to control a DC level for adjusting a reference value used in a manufacturing process of the flash memory device. The fuse sense amplifying circuits are coupled to the bit lines to read data from the bit lines, respectively.

120. 发明授权

US06413922B1 Combination soap bar composition containing monoglyceride sulfonate 有权
标题翻译：含有单酸甘油酯磺酸盐的组合皂条组合物
公开(公告)号：US06413922B1
公开(公告)日：2002-07-02
申请号：US09454105
申请日：1999-12-03
申请人： Je-Kwon Goo , Young-Ho Choi , Moon-Jeong Rang , Tae-Seong Kim , Tae-Kyung Huh , Jung-Jin Choi , Ho-Jeong Ahn
发明人： Je-Kwon Goo , Young-Ho Choi , Moon-Jeong Rang , Tae-Seong Kim , Tae-Kyung Huh , Jung-Jin Choi , Ho-Jeong Ahn
IPC分类号： A61K750
CPC分类号： C11D17/006 , C11D1/123 , C11D1/126 , C11D1/28 , C11D1/29 , C11D10/042
摘要： The present invention relates to a combination soap bar composition containing monoglyceride sulfonates and a method for manufacturing the same. A combination bar composition containing monoglyceride sulfonates of the present invention comprises fatty acid based toilet bars and monoglyceride sulfonates of the following General Formula 1: where R is an alkyl having 7 to 21 carbon atoms, and M is sodium, potassium, triethanolamine, or ammonium.
摘要翻译：本发明涉及含有单酸甘油酯磺酸盐的组合皂条组合物及其制造方法。含有本发明单酸甘油酯磺酸盐的组合棒组合物包含以下通式1的脂肪酸基马桶和单酸甘油酯磺酸盐：其中R是具有7-21个碳原子的烷基，M是钠，钾，三乙醇胺或铵。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式