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111. 发明申请

US20130005033A1 ANTIBODIES TO HUMAN IL-22 有权
标题翻译：人类IL-22的抗体
公开(公告)号：US20130005033A1
公开(公告)日：2013-01-03
申请号：US13477717
申请日：2012-05-22
申请人： Davinder S. Gill , Jing Li , Geertruida M. Veldman , Lynette A. Fouser , Viia Valge-Archer , David C. Lowe , Caroline S. Russell , Suzanne E. Cohen , Albert G. Thom , Ralf R. Minter
发明人： Davinder S. Gill , Jing Li , Geertruida M. Veldman , Lynette A. Fouser , Viia Valge-Archer , David C. Lowe , Caroline S. Russell , Suzanne E. Cohen , Albert G. Thom , Ralf R. Minter
IPC分类号： C12N15/13 , C12N1/21 , C12N1/19 , C12N15/63 , C12N5/10
CPC分类号： C07K16/244 , C07K2317/21 , C07K2317/33 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22). The antibodies can act as antagonists of IL-22 activity, thereby modulating immune responses in general, and those mediated by IL-22 in particular. The disclosed compositions and methods may be used for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.
摘要翻译：本申请提供特异性结合人白细胞介素-22（IL-22）的人抗体及其抗原结合片段。抗体可以作为IL-22活性的拮抗剂，从而调节一般的免疫应答，特别是由IL-22介导的那些。所公开的组合物和方法可用于例如诊断，治疗或预防炎性疾病，自身免疫性疾病，过敏，败血性休克，感染性疾病，移植排斥，癌症和其他免疫系统疾病。

112. 发明申请

US20120320877A1 Method, System and Base Station Subsystem for Realizing Handover in Local Switch 有权
标题翻译：在本地交换机中实现切换的方法，系统和基站子系统
公开(公告)号：US20120320877A1
公开(公告)日：2012-12-20
申请号：US13581335
申请日：2011-04-15
申请人： Jing Li , Xinhui Wang
发明人： Jing Li , Xinhui Wang
IPC分类号： H04W36/00
CPC分类号： H04W36/02 , H04W8/082 , H04W36/10
摘要： The present invention provides a method for implementing a handover in a local switch, and the method comprises: when one party Mobile Station of a call implementing a local switch mode performs a Base Station Subsystem handover, the Base Station Subsystem handover transmits uplink speech data of the Mobile Station which does not need to perform the handover on a local switch link of the Base Station Subsystem and a link between the Base Station Subsystem and a Media Gateway simultaneously. A Base Station Subsystem implementing a handover in a local switch is also provided by the present invention. The present invention can efficiently avoid the speech loss of the Mobile Station performing the handover during the handover, and guarantees that the Mobile Station which needs to perform the handover can receive the speech data of the other party user no matter the Mobile Station is in the original BSS or the target BSS, thus maintaining the call between the two Mobile Stations efficiently.
摘要翻译：本发明提供一种在本地交换机中实现切换的方法，所述方法包括：当实现本地交换模式的呼叫的一方移动台执行基站子系统切换时，基站子系统切换发送上行语音数据不需要在基站子系统的本地交换机链路上执行切换的移动台和基站子系统与媒体网关之间的链路同时进行。本发明还提供了实现本地交换机切换的基站子系统。本发明可以有效地避免在切换期间执行切换的移动台的语音丢失，并且保证需要执行切换的移动台可以接收对方用户的语音数据，无论移动台处于原始BSS或目标BSS，从而有效地保持两个移动台之间的呼叫。

113. 发明授权

US08321517B2 Method and system for processing emails 失效
标题翻译：处理电子邮件的方法和系统
公开(公告)号：US08321517B2
公开(公告)日：2012-11-27
申请号：US12771102
申请日：2010-04-30
申请人： Jing Li , Lin Xie , Shi Jia Zhang , Xiao Jin Zhao
发明人： Jing Li , Lin Xie , Shi Jia Zhang , Xiao Jin Zhao
IPC分类号： G06F15/16
CPC分类号： H04L51/28 , G06Q10/107 , H04L51/14 , H04L51/30
摘要： The present invention provides a method and system for processing emails. The method comprising: receiving a correction request including an identifier of an original email and an incorrect recipient; in response to the correction request, creating a correction record including the identifier of the original email and the incorrect recipient; in response to receiving relevant emails of the original email, determining whether recipients of the relevant emails include the incorrect recipient; and in response to determining that recipients of the relevant emails include the incorrect recipient, processing the relevant emails based on the correction record.
摘要翻译：本发明提供一种处理电子邮件的方法和系统。该方法包括：接收包括原始电子邮件的标识符和不正确接收者的校正请求; 响应于所述校正请求，创建包括原始电子邮件的标识符和不正确接收者的校正记录; 响应收到原始电子邮件的相关电子邮件，确定相关电子邮件的收件人是否包含错误的收件人; 并且响应于确定相关电子邮件的收件人包括不正确的接收者，根据修正记录处理相关电子邮件。

114. 发明申请

US20120249270A1 Providing Multiple Inductors For A Radio Tuner 有权
标题翻译：为无线电调谐器提供多个电感器
公开(公告)号：US20120249270A1
公开(公告)日：2012-10-04
申请号：US13073538
申请日：2011-03-28
申请人： Jing Li , Dan B. Kasha , Aslamali A. Rafi
发明人： Jing Li , Dan B. Kasha , Aslamali A. Rafi
IPC分类号： H03J3/20
CPC分类号： H04B1/18 , H03J5/244
摘要： A method includes receiving a desired channel indication in a radio tuner, determining a band of operation in which the channel is located, and if the channel is within a first band coupling multiple inductors into a resonant tank, and if the desired channel is within a second band coupling a single inductor into the resonant tank.
摘要翻译：一种方法包括在无线电调谐器中接收期望的信道指示，确定信道所位于的操作频带，以及如果信道在将多个电感器耦合到谐振槽内的第一频带内，并且如果期望信道在第二频带将单个电感器耦合到谐振槽中。

115. 发明授权

US08274339B2 Automatic frequency control architecture with digital temperature compensation 有权
标题翻译：具有数字温度补偿功能的自动频率控制架构
公开(公告)号：US08274339B2
公开(公告)日：2012-09-25
申请号：US12770230
申请日：2010-04-29
申请人： Yongping Fan , Jing Li , Ian A. Young
发明人： Yongping Fan , Jing Li , Ian A. Young
IPC分类号： H03L1/02 , H03L7/085
CPC分类号： H03L1/02 , H03B5/1215 , H03B5/1228 , H03B5/1234 , H03B5/124 , H03B5/1265 , H03J2200/10 , H03L7/099 , H03L7/103 , H03L7/18
摘要： A mixed signal circuit architecture is disclosed for automatic frequency control and digital temperature compensation in an LC-PLL system. Some embodiments allow for high-volume manufacturing of products such as microprocessors and chipsets, and other circuits that employ LC-PLL technology. In some embodiments, various capacitor loadings can be selected to compensate for variation associated with process, voltage, temperature, and reference frequency. In addition, a multi-leg capacitor bank can be selectively used to further compensate for temperature variation post-lock, in accordance with some embodiments. A programmable timer can be used in some embodiments to allow for loop settling prior to assessing parameters of interest.
摘要翻译：公开了用于LC-PLL系统中的自动频率控制和数字温度补偿的混合信号电路架构。一些实施例允许诸如微处理器和芯片组的产品的大量制造以及采用LC-PLL技术的其它电路。在一些实施例中，可以选择各种电容器负载以补偿与过程，电压，温度和参考频率相关联的变化。此外，根据一些实施例，可以选择性地使用多支脚电容器组来进一步补偿温度变化后锁定。在一些实施例中可以使用可编程定时器，以便在评估感兴趣的参数之前允许循环结算。

116. 发明授权

US08263562B2 Peptides for preventing or treating liver damage 有权
标题翻译：用于预防或治疗肝损伤的肽
公开(公告)号：US08263562B2
公开(公告)日：2012-09-11
申请号：US13162981
申请日：2011-06-17
申请人： Yun Cheng , Ruihe Yu , Wanzhou Zhao , Jun Zhao , Jing Li
发明人： Yun Cheng , Ruihe Yu , Wanzhou Zhao , Jun Zhao , Jing Li
IPC分类号： A61K38/08
CPC分类号： A61K38/08
摘要： The application of a peptide having sequence of formula I or its derivant in preparing the medicine for preventing or treating liver damage, especially liver damage and hepatitis C is disclosed, Xaa1-Gln-Xaa2-Xaa3-Thr-Ser-Gly-Xaa4 (formula I) wherein, Xaa1 is deletion, Ala, Gly, Val, Leu or Ile, Xaa2 is Thr or Ser, Xaa3 is Tyr, Phe or Trp, and Xaa4 is deletion, Ala, Gly, Val, Leu, Ile or Pro. The composite medicine containing the said peptide, its preparation method, and the polynucleotide for coding the said peptide are also disclosed.
摘要翻译： Xaa1-Gln-Xaa2-Xaa3-Thr-Ser-Gly-Xaa4（式（I））表示具有式I或其衍生物的肽在制备用于预防或治疗肝损伤，特别是肝损伤和丙型肝炎的药物中的应用 I）其中Xaa1是缺失型，Ala，Gly，Val，Leu或Ile，Xaa2是Thr或Ser，Xaa3是Tyr，Phe或Trp，Xaa4是缺失，Ala，Gly，Val，Leu，Ile或Pro。还公开了含有所述肽的复合药物及其制备方法和用于编码所述肽的多核苷酸。

117. 发明申请

US20120224853A1 METHOD AND DEVICE FOR SENDING UPLINK BURST DATA IN PASSIVE OPTICAL NETWORK SYSTEM 有权
标题翻译：用于在被动光网络系统中发送上行链路数据的方法和装置
公开(公告)号：US20120224853A1
公开(公告)日：2012-09-06
申请号：US13473166
申请日：2012-05-16
申请人： Dongyu Geng , Dongning Feng , Jing Li , Raymond W.K. Leung , Frank Effenberger
发明人： Dongyu Geng , Dongning Feng , Jing Li , Raymond W.K. Leung , Frank Effenberger
IPC分类号： H04B10/00
CPC分类号： H04L7/041 , H04Q11/0067 , H04Q2011/0064
摘要： A method for sending uplink burst data in a passive optical network (PON) system includes: sending a synchronization pattern of the uplink burst data, the synchronization pattern being of a length, which is an integer multiple of 66 bits, and being formed by connection of 66-bit unit gene blocks; sending a burst delimiter (BD) of the uplink burst data; sending a forward error correction (FEC)-protected data in the uplink burst data; and sending an end of burst (EOB) delimiter of the uplink burst data. The technical solutions in the embodiments allow the use of a less complex equalizer at the reception end of a high-speed PON system.
摘要翻译：一种用于在无源光网络（PON）系统中发送上行链路突发数据的方法包括：发送上行链路突发数据的同步模式，同步模式长度为66比特的整数倍，并通过连接形成的66位单元基因块; 发送上行链路突发数据的脉冲串定界符（BD）; 在上行链路突发数据中发送前向纠错（FEC）保护数据; 并发送上行链路突发数据的突发（EOB）定界符的结束。实施例中的技术方案允许在高速PON系统的接收端使用较不复杂的均衡器。

118. 发明授权

US08202971B2 Process for preparing compounds of chitosan saccharified with aminosugar 失效
标题翻译：用氨基糖糖化糖壳化合物的方法
公开(公告)号：US08202971B2
公开(公告)日：2012-06-19
申请号：US12499767
申请日：2009-07-08
申请人： Xiguang Chen , Jing Li , Xiaojie Cheng , Tao Jiang
发明人： Xiguang Chen , Jing Li , Xiaojie Cheng , Tao Jiang
IPC分类号： C08B37/08
CPC分类号： C08B37/003
摘要： A process for preparing compounds of chitosan saccharified with aminosugar, adopts chitosan derivatives, aminosugar derivatives and anhydride derivatives as raw materials to synthesize target products. The process comprises: covalently bonding an anhydride derivative as a bonding arm to an aminosugar derivative, so as to form a monosaccharide derivative having an end group of carboxyl; and then covalently bonding the monosaccharide derivative having an end group of carboxyl to a primary amino group of a chitosan derivative via the carboxyl, so as to form a compound of chitosan saccharified with aminosugar.
摘要翻译：用氨基糖糖化糖壳化合物的方法，采用壳聚糖衍生物，氨基糖衍生物和酸酐衍生物为原料合成目标产物。该方法包括：将作为结合臂的酸酐衍生物与氨基糖衍生物共价键合，形成具有羧基端基的单糖衍生物; 然后通过羧基将具有羧基末端基团的单糖衍生物共价键合到壳聚糖衍生物的伯氨基上，以形成用氨基糖糖化的壳聚糖化合物。

119. 发明授权

US08192995B2 Method of correction of particle interference to hemoglobin measurement 有权
标题翻译：校正颗粒干扰血红蛋白测量方法
公开(公告)号：US08192995B2
公开(公告)日：2012-06-05
申请号：US12616273
申请日：2009-11-11
申请人： Shuliang Zhang , Jiuliu Lu , Min Zheng , Eric M. Grace , Jing Li , Maritza Lavernia , Ted W. Britton
发明人： Shuliang Zhang , Jiuliu Lu , Min Zheng , Eric M. Grace , Jing Li , Maritza Lavernia , Ted W. Britton
IPC分类号： G01N33/72 , G01N33/48
CPC分类号： G01N33/721 , G01N33/491 , Y10T436/10 , Y10T436/101666 , Y10T436/25 , Y10T436/25125
摘要： A method of correction of particle interference to hemoglobin measurement of a blood sample on a hematology analyzer is provided. The method includes mixing an aliquot of a blood sample with a lytic reagent to lyse red blood cells and forming a sample mixture; measuring absorbance of the sample mixture at a predetermined wavelength of a hemoglobin chromogen formed in the sample mixture, and obtaining an apparent hemoglobin concentration of the blood sample using obtained absorbance; measuring concentration and size of cellular particles remaining in the sample mixture; removing contribution of the cellular particles to the apparent hemoglobin concentration using the concentration and the size of the cellular particles to obtain a corrected hemoglobin concentration of the blood sample; and reporting the corrected hemoglobin concentration of the blood sample.
摘要翻译：提供了一种在血液分析仪上校正血液样品的血红蛋白测量的粒子干扰的方法。该方法包括将血样的等分试样与裂解试剂混合以溶解红细胞并形成样品混合物; 测量在样品混合物中形成的血红蛋白色原子的预定波长处的样品混合物的吸光度，并使用所获得的吸光度获得血液样品的表观血红蛋白浓度; 测量残留在样品混合物中的细胞颗粒的浓度和尺寸; 使用细胞颗粒的浓度和大小去除细胞颗粒对表观血红蛋白浓度的贡献，以获得血液样品的校正血红蛋白浓度; 并报告血样的校正血红蛋白浓度。

120. 发明授权

US08187603B2 Antibodies to human IL-22 有权
公开(公告)号：US08187603B2
公开(公告)日：2012-05-29
申请号：US12474644
申请日：2009-05-29
申请人： Davinder S. Gill , Jing Li , Geertruida M. Veldman , Lynette A. Fouser , Viia Valge-Archer , David C. Lowe , Caroline S. Russell , Suzanne E. Cohen , Albert G. Thom , Ralph R. Minter
发明人： Davinder S. Gill , Jing Li , Geertruida M. Veldman , Lynette A. Fouser , Viia Valge-Archer , David C. Lowe , Caroline S. Russell , Suzanne E. Cohen , Albert G. Thom , Ralph R. Minter
IPC分类号： C07K16/24 , A61K39/395
CPC分类号： C07K16/244 , C07K2317/21 , C07K2317/33 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22). The antibodies can act as antagonists of IL-22 activity, thereby modulating immune responses in general, and those mediated by IL-22 in particular. The disclosed compositions and methods may be used for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.

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