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101. 发明授权

US5766160A Variable stiffness coils 失效
标题翻译：可变刚度线圈
公开(公告)号：US5766160A
公开(公告)日：1998-06-16
申请号：US480042
申请日：1995-06-06
申请人： Gene Samson , Ivan Sepetka , U. Hiram Chee , Christopher G. M. Ken , Nga T. Van
发明人： Gene Samson , Ivan Sepetka , U. Hiram Chee , Christopher G. M. Ken , Nga T. Van
IPC分类号： A61M31/00 , A61B17/12 , A61B17/00
CPC分类号： A61B17/1215 , A61B17/12022 , A61B17/12109 , A61B17/12145
摘要： This invention is an implantable vaso-occlusive device. It is a helically wound coil having a central section along its longitudinal axis which is somewhat stiffer than at least one of its end regions.
摘要翻译：本发明是可植入血管闭塞装置。它是螺旋缠绕的线圈，其沿其纵向轴线具有中心部分，该中心部分比其端部区域中的至少一个稍微更硬。

102. 发明授权

US5749894A Aneurysm closure method 失效
公开(公告)号：US5749894A
公开(公告)日：1998-05-12
申请号：US588195
申请日：1996-01-18
申请人： Erik T. Engelson
发明人： Erik T. Engelson
IPC分类号： A61B17/00 , A61B17/12
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B17/12186 , A61B17/12195 , A61B2017/005 , A61B2017/1205 , A61B2017/12063
摘要： This is a procedure for stabilizing or filling an aneurysm in the vasculature. The procedure involves the introduction into the aneurysm of a solid vaso-occlusive device such as a coil or braid and a polymeric composition which may be reformed or solidified in situ. The solid vaso-occlusive device is at least partially surrounded or enveloped by that polymeric composition. The polymeric composition is reformed via light, heat, R.F. or the like to form a rigid mass with the solid vaso-occlusive device. These steps may be carried out sequentially or the steps of introducing the vaso-occlusive device and reforming the polymeric composition may be carried out simultaneously. The procedure may be accomplished using intravascular catheters to access the desired site and to deliver the noted materials.

103. 发明授权

US5749891A Multiple layered vaso-occlusive coils 失效
公开(公告)号：US5749891A
公开(公告)日：1998-05-12
申请号：US779378
申请日：1997-01-07
申请人： Christopher G. M. Ken , Erik T. Engelson
发明人： Christopher G. M. Ken , Erik T. Engelson
IPC分类号： A61F2/82 , A61B17/12 , A61B17/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61B2017/00526
摘要： This is an implantable vaso-occlusive device. It is a complex, helically wound coil having multiple secondary layers of primary windings. The final shape is often chunky in nature and may be used in the approximate shape of an anatomical cavity. It may be deployed in the approximate shape of a sphere, an ovoid, or other distorted spherical shape. The device is a self-forming shape made from a pre-formed linear vaso-occlusion member. Fibers may be introduced onto the device and affixed to the pre-formed linear member. The constituent member may be also be covered with a fibrous braid. The device is typically introduced through a catheter. The device is passed axially through the catheter sheath and assumes its form upon exiting the catheter without further action. The invention also includes methods of winding the anatomically shaped vaso-occlusive device into appropriately shaped forms and annealing them to form various devices.

104. 发明授权

US5749837A Enhanced lubricity guidewire 失效
标题翻译：增强润滑性导丝
公开(公告)号：US5749837A
公开(公告)日：1998-05-12
申请号：US695185
申请日：1996-08-01
申请人： Thomas J. Palermo , Gene Samson , Gregory E. Mirigian , U. Hiram Chee
发明人： Thomas J. Palermo , Gene Samson , Gregory E. Mirigian , U. Hiram Chee
IPC分类号： A61M25/00 , A61B5/00
CPC分类号： A61M25/09 , A61M2025/0046 , A61M2025/09091 , A61M2025/09133 , A61M2025/09175
摘要： This invention is a surgical device. It is a guidewire for use in a catheter and is used for accessing a targeted site in a lumen system of a patient's body. The guidewire or guidewire section may be of a stainless steel or a high elasticity metal alloy, preferably a Ni--Ti alloy, having specified physical parameters. The guidewire is especially useful for accessing peripheral or soft tissue targets. A special variation of the inventive guidewire includes the coating of the wire with a tie layer and then with a one or more lubricious polymers to enhance its suitability for use within catheters and with the interior of vascular lumen.
摘要翻译：本发明是一种手术装置。它是用于导管的导丝，用于进入患者身体的管腔系统中的目标部位。导线或导丝部分可以是具有特定物理参数的不锈钢或高弹性金属合金，优选Ni-Ti合金。导丝对于访问外周或软组织靶是特别有用的。本发明的导丝的特殊变型包括用连接层涂覆线材，然后用一种或多种润滑聚合物涂覆，以增强其在导管内和血管腔内部使用的适用性。

105. 发明授权

US5695483A Kink-free spiral-wound catheter 失效
标题翻译：无弯曲螺旋缠绕导管
公开(公告)号：US5695483A
公开(公告)日：1997-12-09
申请号：US516411
申请日：1995-08-17
申请人： Gene Samson
发明人： Gene Samson
IPC分类号： A61L29/04 , A61L29/06 , A61L29/08 , A61M25/00
CPC分类号： A61L29/08 , A61L29/041 , A61L29/049 , A61L29/06 , A61M25/005 , A61M25/0053
摘要： This invention is a surgical device. In particular, it is a catheter suitable for treating a tissue target within the body, which target is accessible through the vascular system. Central to the invention is the use of stiffener ribbons, typically metallic, wound within the catheter body in such a way as to create a catheter having controllable stiffness.
摘要翻译：本发明是一种手术装置。特别地，它是适合于治疗身体内的组织靶的导管，该靶可通过血管系统进入。本发明的中心是使用加强筋，通常是金属的，缠绕在导管体内，以便产生具有可控刚度的导管。

106. 发明授权

US5636642A Deformable tip super elastic guidewire 失效
标题翻译：可变形尖端超弹性导丝
公开(公告)号：US5636642A
公开(公告)日：1997-06-10
申请号：US428819
申请日：1995-04-25
申请人： Thomas J. Palermo
发明人： Thomas J. Palermo
IPC分类号： A61M25/01 , A61M25/00 , A61M25/09 , A61B5/00
CPC分类号： A61M25/09 , A61M2025/0046 , A61M2025/09091 , A61M2025/09133 , A61M2025/09175
摘要： This invention is a surgical device. It is a guidewire for use in a catheter and is used for accessing a targeted site within a system of lumen within a patient's body. The guidewire may be of a high elasticity metal alloy, preferably a Ni--Ti alloy, having specified physical parameters, and is especially useful for accessing peripheral or soft tissue targets. The "necked" guidewire tip also forms a specific parameter of the invention.
摘要翻译：本发明是一种手术装置。它是用于导管中的导丝，并且用于进入患者体内的内腔系统内的目标部位。导丝可以是具有特定物理参数的高弹性金属合金，优选Ni-Ti合金，并且特别适用于接近外周或软组织靶。 “颈缩”导丝尖也形成本发明的具体参数。

107. 发明授权

US5624461A Three dimensional in-filling vaso-occlusive coils 失效
标题翻译：三维填充血管闭塞线圈
公开(公告)号：US5624461A
公开(公告)日：1997-04-29
申请号：US467403
申请日：1995-06-06
申请人： Michael J. Mariant
发明人： Michael J. Mariant
IPC分类号： A61B17/00 , A61B17/12 , A61M29/00
CPC分类号： A61B17/12145 , A61B17/12022 , A61B17/1215
摘要： This is an implantable vaso-occlusive device. It is a complex, helically wound coil comprised of a primary helically wound coil which is then wound into a specific secondary shape. The final shape upon deployment is in the approximate shape of an anatomical cavity. upon deployment, the device first fills the periphery of the cavity and then continues to infill the center. The device is a self-forming shape made from a pre-formed linear helically wound. Fibers may be introduced onto the device and affixed to the pre-formed linear member. The constituent member may be also be covered with a fibrous braid. The device is typically introduced through a catheter. The device is passed axially through the catheter sheath and assumes its form upon exiting the catheter without further action. The invention also includes methods of winding the vaso-occlusive device into appropriately shaped forms and annealing them.
摘要翻译：这是一种植入式血管闭塞装置。它是一个复杂的，螺旋缠绕的线圈，其包括初级螺旋缠绕线圈，然后将其缠绕成特定的次级形状。部署后的最终形状为解剖腔的近似形状。在展开时，装置首先填充空腔的周边，然后继续填充中心。该装置是由预先形成的线性螺旋缠绕制成的自形成形状。纤维可以引入到装置上并固定到预成形的线性构件上。构成部件也可以用纤维编织物覆盖。该装置通常通过导管引入。该装置轴向穿过导管护套，并且在离开导管时采取其形式，而无需进一步的动作。本发明还包括将血管闭塞装置卷绕成适当形状的形状并退火的方法。

108. 发明授权

US5599326A Catheter with multi-layer section 失效
标题翻译：导管与多层截面
公开(公告)号：US5599326A
公开(公告)日：1997-02-04
申请号：US359469
申请日：1994-12-20
申请人： Mark Carter
发明人： Mark Carter
IPC分类号： A61M25/00 , A61M25/16
CPC分类号： A61M25/0045
摘要： This catheter is suitable for treating a tissue target within the body, which target is accessible through the vascular system. Central to the catheter is the use of a multi-component section having an interior stiffener comprising a spirally cut tubing member and an exterior tubing member. Depending upon the choice of materials of construction for the interior and exterior layers (and their respective thicknesses), the section may be placed at any place within the length of the catheter. The multi-component section is kink-resistant, has good pushability and flexibility, and (in some variations) has variable flexibility along the axis of the spirally cut section.
摘要翻译：该导管适用于治疗身体内的组织靶，该靶可通过血管系统进入。导管的中心是使用具有内部加强件的多部件部件，该内部加强件包括螺旋切割的管件和外管件。根据内部和外部层的结构材料的选择（及其各自的厚度），该部分可以放置在导管长度内的任何位置。多组分部分是抗扭结的，具有良好的推挤性和柔性，并且（在一些变型中）沿着螺旋切割部分的轴线具有可变的柔性。

109. 发明授权

US5578074A Implant delivery method and assembly 失效
标题翻译：植入物交付方式和装配
公开(公告)号：US5578074A
公开(公告)日：1996-11-26
申请号：US363232
申请日：1994-12-22
申请人： Gregory E. Mirigian
发明人： Gregory E. Mirigian
IPC分类号： A61F2/82 , A61B17/00 , A61B17/12 , A61F2/00 , A61F2/06
CPC分类号： A61B17/1214 , A61B17/12022 , A61B2017/12063 , A61B2017/12068 , A61B2017/12077 , A61F2002/30095 , A61F2210/0023
摘要： A thermally activated occlusive implant delivery assembly is provided. The assembly includes an occlusive implant device and a pusher. The pusher has a distal section and a proximal section. The distal section includes a coupling portion which is shape memory material and exhibits different configurations depending on the coupling portion's temperature. The coupling portion interlockingly engages the implant when it is in one of the configurations and releases the implant from interlocking engagement therewith when in another one of the configurations. In operation, the assembly is introduced into the body of a mammal via a guide catheter suited for the particular lumen being navigated. When the implant is positioned at the desired site, the coupling portion of the pusher is thermally activated to effect the return of its original, pre-set configuration, which is originally formed to release the implant from interlocking engagement therewith. The pusher can then be readily removed from the mammal without imparting any significant force on the implant during retraction.
摘要翻译：提供热活化闭塞植入物递送组件。组件包括闭塞植入装置和推动器。推动器具有远端部分和近端部分。远侧部分包括耦合部分，其是形状记忆材料，并且根据耦合部分的温度呈现不同的构型。当处于其中一个构造时，联接部分与植入物互锁地接合，并且当处于另一种构造时，将植入物与其互锁接合释放。在操作中，组件通过适合于正在导航的特定管腔的导管引入哺乳动物体内。当植入物定位在期望的位置时，推动器的联接部分被热活化，以实现其原始形成的初始构造的返回，其原始形成为将植入物与其互锁接合释放。然后可以从哺乳动物容易地移除推动器，而不会在收缩期间对植入物施加任何显着的力。

110. 发明授权

US5437632A Variable stiffness balloon catheter 失效
标题翻译：可变刚度球囊导管
公开(公告)号：US5437632A
公开(公告)日：1995-08-01
申请号：US71284
申请日：1993-06-02
申请人： Erik T. Engelson
发明人： Erik T. Engelson
IPC分类号： A61M25/00 , A61M29/02 , A61M25/10
CPC分类号： A61M29/02 , A61M25/0045 , A61M25/0054 , A61M2025/0079 , A61M2025/1063
摘要： This invention is a single-lumen balloon catheter and assembly having a variable stiffness shaft that allows for greater guidewire trackability and proximal pushability than previous designs. The catheter has an elongate tubular body that is made of inner and outer coaxial tubes, the inner tube being made of proximal and distal sections, the proximal section being stiffer than the distal section and the distal section being stiffer than the outer tube.
摘要翻译：本发明是具有可变刚度轴的单腔气囊导管和组件，其允许比以前的设计更大的导丝跟踪性和近端推挤性。导管具有由内外同轴管制成的细长管状体，内管由近端和远端部分制成，近端部分比远端部分更硬，远端部分比外管更硬。

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