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101. 发明授权

US06906074B2 2-phenylpiperazine derivatives 失效
标题翻译： 2-苯基哌嗪衍生物
公开(公告)号：US06906074B2
公开(公告)日：2005-06-14
申请号：US10370918
申请日：2003-02-20
申请人： Takashi Ogino , Yukari Konishi , Kunihiko Higashiura , Kazuhito Furukawa
发明人： Takashi Ogino , Yukari Konishi , Kunihiko Higashiura , Kazuhito Furukawa
IPC分类号： A61P29/00 , C07D241/04 , C07D241/08 , C07D401/06 , C07D403/04 , C07D403/06 , A61K31/50 , A61K31/501
CPC分类号： C07D401/06 , C07D241/04 , C07D241/08 , C07D403/04 , C07D403/06
摘要： A 2-phenylpiperazine derivative represented by the formula (I) or a pharmaceutically acceptable salt, hydrate, or complex thereof: wherein each of X1 and X3 is oxygen or two hydrogen atoms, X2 O, NH, NCH3, or CH2, n is an integer of 0 or 1, R1 is hydrogen or lower alkyl and R2 is hydrogen, cyano, tetrazolyl, aminotriazolyl , mesyl, t-butoxycarbonyl, or a lower alkyl which may be optionally substituted, R3 is hydrogen, halogen, lower alkyl or lower alkoxy, each of R4 and R5 is hydrogen, lower alkoxy or trifluoromethyl, and a broken line indicates a single or double bond. The derivative may be used as a tachykinin antagonist in the treatment of diseases of the digestive system, nervous system and respiratory system, inflammation, allergy, carcinoid syndrome, chronic pain, headache, Crohn disease, depression and vomiting.
摘要翻译：由式（I）表示的2-苯基哌嗪衍生物或其药学上可接受的盐，水合物或络合物：其中X 1和X 3中的每一个为氧或两个氢原子，X 2 O，NH，NCH 3或CH 2，n是0或1的整数，R 1， R 1是氢或低级烷基，R 2是氢，氰基，四唑基，氨基三唑基，甲磺酰基，叔丁氧基羰基或可任意取代的低级烷基，R 3 R 4和R 5中的每一个是氢，低级烷氧基或三氟甲基，虚线表示一个单键或双键。该衍生物可用作速激肽拮抗剂治疗消化系统疾病，神经系统和呼吸系统，炎症，变态反应，类癌综合征，慢性疼痛，头痛，克罗恩病，抑郁症和呕吐。

102. 发明授权

US06884868B1 Cyclic hexapeptides having antibiotic activity 失效
标题翻译：具有抗生素活性的环状六肽
公开(公告)号：US06884868B1
公开(公告)日：2005-04-26
申请号：US09926385
申请日：2000-04-25
申请人： Takashi Tojo , Hidenori Ohki , Nobuyuki Shiraishi , Takahiro Matsuya , Hiroshi Matsuda , Kenji Murano , David Barrett , Takashi Ogino , Keiji Matsuda , Masaharu Ichihara , Norio Hashimoto , Atsushi Kanda , Atsushi Ohigashi
发明人： Takashi Tojo , Hidenori Ohki , Nobuyuki Shiraishi , Takahiro Matsuya , Hiroshi Matsuda , Kenji Murano , David Barrett , Takashi Ogino , Keiji Matsuda , Masaharu Ichihara , Norio Hashimoto , Atsushi Kanda , Atsushi Ohigashi
IPC分类号： A61K38/00 , A61P31/00 , A61P31/10 , A61P43/00 , C07K7/56 , C07K7/50
CPC分类号： C07K7/56 , A61K38/00
摘要： This invention relates to new polypeptide compound represented by general formula (I), wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on β-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.
摘要翻译：本发明涉及由通式（I）表示的新的多肽化合物，其中R 1，R 2，R 3，R 3， 4，R 5和R 6如描述中所定义，或其盐具有抗微生物活性（特别是抗真菌活性），对β的抑制活性 -1,3-葡聚糖合酶，其制备方法，涉及包含其的药物组合物，以及用于预防和/或治疗感染性疾病的方法，所述传染病包括人类卡氏肺囊虫感染（例如肺孢子虫卡氏肺炎）或动物。

103. 发明授权

US06880928B2 Ink jet recording method and ink jet recording paper 有权
标题翻译：喷墨记录方法和喷墨记录纸
公开(公告)号：US06880928B2
公开(公告)日：2005-04-19
申请号：US10457432
申请日：2003-06-10
申请人： Kiyoshi Hosoi , Chizuru Koga , Takashi Ogino
发明人： Kiyoshi Hosoi , Chizuru Koga , Takashi Ogino
IPC分类号： B41J2/01 , B41M5/00 , B41M5/50 , B41M5/52 , C09D11/00 , D21H17/66 , D21H27/00
CPC分类号： B41M5/5218 , B41M5/508 , C09D11/322 , C09D11/40
摘要： In an ink jet recording method, a surface of a recording paper, in which a base paper contains a pulp fiber and a filler, one surface of the base paper being coated with a polyvalent metal salt in a coating amount of from 0.1 to 3 g/m2, having a basis weight of from 63 to 100 g/m2 and an internal bond strength of from 0.05 to 0.2 N·m is printed using an ink of at least one color made of at least a pigment, a water-soluble organic solvent, water and a surfactant and having a surface tension of from 25 to 37 mN/m. According to the method, the color reproduction is improved, the inter color bleeding and the feathering of characters are reduced, the double-sided printability is provided by reducing curling and cockling occurring immediately after printing, and curling and cockling occurring after allowing to stand and drying are also reduced.
摘要翻译：在喷墨记录方法中，在原纸中含有纸浆纤维和填料的记录纸的表面，涂布量为0.1〜3g的原纸的一面被多价金属盐涂布， / m 2，基重为63〜100g / m 2，内部结合强度为0.05〜0.2Nm，使用至少一种颜色至少由颜料，水溶性有机溶剂，水和表面活性剂制成，表面张力为25至37mN / m。根据该方法，颜色再现性得到改善，字符的色彩渗透和羽化减少，通过减少印刷后立即发生卷曲和起皱，并且在允许静置后发生卷曲和起皱，提供双面印刷性干燥也减少。

104. 发明授权

US06877807B2 Vehicular under-seat compartment mechanism 有权
标题翻译：车辆下座舱机构
公开(公告)号：US06877807B2
公开(公告)日：2005-04-12
申请号：US10701406
申请日：2003-11-04
申请人： Koji Mizuno , Yasuji Morinishi , Shingo Kutomi , Takashi Ogino
发明人： Koji Mizuno , Yasuji Morinishi , Shingo Kutomi , Takashi Ogino
IPC分类号： B60N2/90 , B60N2/30 , B60R7/04 , A47C7/62
CPC分类号： B60R7/043 , B60N2/305
摘要： To utilize limited space in a vehicle cabin, a vehicular under-seat compartment mechanism includes a hinge mechanism, a compartment and a lock mechanism. The hinge mechanism interconnects a seat-frame and a seat-cushion in such a manner that the seat-cushion is pivotally rotatable with respect to the seat-frame. The compartment is disposed in the under-seat space under the seat and is formed an opening upwardly. The lock mechanism, integrated with the hinge mechanism, locks the seat-cushion at an upright position, at which the seat-cushion is pivotally flipped up about the hinge mechanism so that the compartment is accessible.
摘要翻译：为了利用车厢内的有限空间，车辆下座舱机构包括铰链机构，隔间和锁定机构。铰链机构以座椅坐垫相对于座椅框架可枢转地旋转的方式将座椅框架和座垫相互连接。隔间设置在座椅下方的下座位空间中，并且向上形成开口。与铰链机构一体化的锁定机构将座垫锁定在直立位置处，座椅坐垫围绕铰链机构枢转地翻转，使得隔间可接近。

105. 发明授权

US06473321B2 Semiconductor integrated circuit and nonvolatile semiconductor memory 失效
标题翻译：半导体集成电路和非易失性半导体存储器
公开(公告)号：US06473321B2
公开(公告)日：2002-10-29
申请号：US09883237
申请日：2001-06-19
申请人： Jiro Kishimoto , Hiroshi Sato , Satoshi Noda , Tatsuya Ishii , Shoji Kubono , Takashi Ogino
发明人： Jiro Kishimoto , Hiroshi Sato , Satoshi Noda , Tatsuya Ishii , Shoji Kubono , Takashi Ogino
IPC分类号： H02M318
CPC分类号： H02M3/073 , G11C16/30 , H02M2003/075
摘要： For a semiconductor integrated circuit having an internal booster circuit such as a flash memory, voltage booster circuits capable of generating a boosted voltage 10 times or more as high as a relatively low source voltage is to be realized. Charge pumps for carrying out first stage voltage boosting on the basis of a source voltage are configured of parallel capacity type units, and charge pumps for carrying out second stage voltage boosting on the basis of the boosted voltage generated by the first charge pumps are configured of serial capacity type units.
摘要翻译：对于具有诸如闪速存储器的内部升压电路的半导体集成电路，可以实现能够产生相当低的源电压的10倍或更高的升压电压的升压电路。基于源电压进行第一级升压的充电泵由并联容量型单元构成，并且基于由第一电荷泵产生的升压电压进行第二级升压的电荷泵由串口容量型号。

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