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101. 发明申请

US20110206902A1 FUSER MEMBER 有权
标题翻译： FUSER会员
公开(公告)号：US20110206902A1
公开(公告)日：2011-08-25
申请号：US12712221
申请日：2010-02-25
申请人： Kock-Yee Law , Hong Zhao
发明人： Kock-Yee Law , Hong Zhao
IPC分类号： B32B3/00
CPC分类号： G03G15/2057 , G03G2215/1676 , Y10T428/1393 , Y10T428/24521 , Y10T428/24612
摘要： The present teachings provide a fuser member. The fuser member includes a substrate, a functional layer disposed on the substrate, and an outer layer disposed on the functional layer. The outer layer includes silicon having a texture, and a conformal oleophobic coating disposed on the silicon.
摘要翻译：本教导提供定影器构件。定影器构件包括衬底，设置在衬底上的功能层和设置在功能层上的外层。外层包括具有纹理的硅，以及设置在硅上的保形疏油涂层。

102. 发明申请

US20110157277A1 Superoleophobic and Superhydrophobic Surfaces And Method For Preparing Same 有权
标题翻译：超疏油和超疏水表面及其制备方法
公开(公告)号：US20110157277A1
公开(公告)日：2011-06-30
申请号：US12647977
申请日：2009-12-28
申请人： Hong Zhao , Kock-Yee Law
发明人： Hong Zhao , Kock-Yee Law
IPC分类号： B41J2/135 , G03F7/20 , B32B3/30
CPC分类号： B41J2/162 , B05D1/185 , B05D1/60 , B05D5/083 , B05D7/02 , B05D2350/60 , B08B17/06 , B08B17/065 , B41J2/1606 , B41J2/1628 , B41J2/1631 , B41J2/1632 , B41J2/1634 , B41J2/1642 , B41J2/1645 , B41J2/1646 , Y10T428/24612
摘要： A process for preparing a flexible device having a superoleophobic surface comprising providing a flexible substrate; disposing a silicon layer on the flexible substrate; using photolithography to create a textured pattern in the silicon layer on the substrate wherein the textured pattern comprises a groove structure; and chemically modifying the textured surface by disposing a conformal oleophobic coating thereon; to provide a flexible device having a superoleophobic surface.
摘要翻译：一种制备具有超疏油表面的柔性装置的方法，包括提供柔性基底; 在柔性基板上设置硅层; 使用光刻法在所述衬底上的所述硅层中形成纹理图案，其中所述纹理图案包括凹槽结构; 并通过在其上设置共形疏油涂层来化学改性织构表面; 以提供具有超疏油表面的柔性装置。

103. 发明申请

US20110122210A1 Image Conditioning Coating 有权
标题翻译：图像调理涂层
公开(公告)号：US20110122210A1
公开(公告)日：2011-05-26
申请号：US12625472
申请日：2009-11-24
申请人： Varun Sambhy , Bryan J. Roof , Kock-Yee Law , Hong Zhao
发明人： Varun Sambhy , Bryan J. Roof , Kock-Yee Law , Hong Zhao
IPC分类号： B41J2/01 , C09D183/04
CPC分类号： C09D183/04
摘要： A contact leveling surface for an ink jet imaging member comprising a low adhesion coating, wherein when the low adhesion coating is disposed on a contact leveling surface, jetted drops of ultra-violet gel ink exhibit a low sliding angle with the contact leveling surface, wherein the low sliding angle is less than about 1° to less than about 30°.
摘要翻译：一种用于喷墨成像构件的接触平整表面，其包括低粘附性涂层，其中当低粘合性涂层设置在接触平整表面上时，喷射的紫外线凝胶墨滴与接触平整表面呈现低滑动角，其中低滑动角小于约1°至小于约30°。

104. 发明授权

US07928095B2 Treatment of resistant or refractory cancers with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin 失效
$Treatment of resistant or refractory cancers with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin$
标题翻译：用7-乙基-10-羟基喜树碱的多臂聚合物缀合物治疗耐药性或难治性癌症
公开(公告)号：US07928095B2
公开(公告)日：2011-04-19
申请号：US12028378
申请日：2008-02-08
申请人： Hong Zhao , Puja Sapra
发明人： Hong Zhao , Puja Sapra
IPC分类号： A61K31/33 , A61K31/194 , A61K31/235 , A61K31/426 , A61P3/10
CPC分类号： A61K47/552 , A61K47/55 , A61K47/60
摘要： A method of treating a resistant or refractory cancer in a mammal includes administering an effective amount of a compound of to the mammal. In preferred aspects, the cancer is resistant or refractory to CPT-11 or CPT therapy.
摘要翻译：在哺乳动物中治疗耐药性或难治性癌症的方法包括向哺乳动物施用有效量的化合物。在优选的方面，癌症对CPT-11或CPT治疗具有抗性或难治性。

105. 发明授权

US07897647B2 Releasable polymeric conjugates based on aliphatic biodegradable linkers 失效
标题翻译：基于脂肪族可生物降解接头的可释放聚合物共轭物
公开(公告)号：US07897647B2
公开(公告)日：2011-03-01
申请号：US11502108
申请日：2006-08-09
申请人： Hong Zhao , Richard B. Greenwald , Annapurna Pendri
发明人： Hong Zhao , Richard B. Greenwald , Annapurna Pendri
IPC分类号： A01N33/08
CPC分类号： C07D333/34 , A61K38/00 , A61K47/60 , C07C271/16 , C07C271/20 , C07C271/22 , C07C317/28 , C07D207/452 , C07D277/16 , C07K14/43595
摘要： Activated polymeric bicine derivatives such as as well as conjugates made therewith are disclosed. Methods of making and using the bicine derivatives are also disclosed.
摘要翻译：公开了活性聚合物双金属衍生物，以及由其制备的缀合物。还公开了制备和使用双金属衍生物的方法。

106. 发明授权

US07868131B2 Methods of preparing polymers having terminal amine groups 失效
标题翻译：制备具有末端胺基团的聚合物的方法
公开(公告)号：US07868131B2
公开(公告)日：2011-01-11
申请号：US11508507
申请日：2006-08-23
申请人： Hong Zhao , Belen Rubio , Jing Xia
发明人： Hong Zhao , Belen Rubio , Jing Xia
IPC分类号： C08G79/02 , C08G79/08 , C08G73/00
CPC分类号： C08G65/33303 , A61K47/60
摘要： The present invention is directed to methods of preparing linear polymers such as polyalkylene oxides containing a terminal amine in high purity. One preferred method includes reacting a polyalkylene oxide such as polyethylene glycol containing a terminal azide with a phosphine-based reducing agent such as triphenylphosphine or an alkali metal borohydride reducing agent such as sodium borohydride in a solvent to reflux. The resultant polymer-amines are of sufficient purity so that expensive and time consuming purification steps required for pharmaceutical grade polymers are avoided.
摘要翻译：本发明涉及制备高纯度的含有末端胺的聚环氧烷的线性聚合物的方法。一种优选的方法包括在溶剂中使含有末端叠氮化物的聚乙二醇与膦类还原剂如三苯基膦或碱金属硼氢化物还原剂如硼氢化钠的聚环氧烷反应进行反应。得到的聚合物胺具有足够的纯度，因此避免了医药级聚合物所需的昂贵且耗时的纯化步骤。

107. 发明申请

US20100279408A1 POLYMERIC SHORT INTERFERING RNA CONJUGATES 审中-公开
标题翻译：聚合短链干扰RNA结合
公开(公告)号：US20100279408A1
公开(公告)日：2010-11-04
申请号：US12445814
申请日：2007-11-27
申请人： Hong Zhao
发明人： Hong Zhao
IPC分类号： C07H21/02 , C12N5/00
CPC分类号： C12N15/111 , A61K47/60 , C12N15/1135 , C12N2310/14 , C12N2310/351 , C12N2320/51
摘要： The present invention provides polymeric siRNA conjugates. Methods for down-regulation of gene expression in vivo and in vitro and for inhibition of the growth of cancer cells using the conjugates are also disclosed.
摘要翻译：本发明提供了聚合物siRNA缀合物。还公开了在体内和体外下调基因表达以及使用缀合物抑制癌细胞生长的方法。

108. 发明申请

US20100048205A1 INTELLIGENT NETWORK SELECTION BASED ON QUALITY OF SERVICE AND APPLICATIONS OVER DIFFERENT WIRELESS NETWORKS 有权
标题翻译：基于不同无线网络的服务质量和应用的智能网络选择
公开(公告)号：US20100048205A1
公开(公告)日：2010-02-25
申请号：US12197830
申请日：2008-08-25
申请人： Ann C. Guilford , Mike Verstegen , Hong Zhao
发明人： Ann C. Guilford , Mike Verstegen , Hong Zhao
IPC分类号： H04Q7/20
CPC分类号： H04W48/18 , H04M15/8038 , H04M2215/34 , H04W28/0247 , H04W28/08 , H04W28/24
摘要： A system and method for selecting a wireless network is disclosed. The method relates to selecting a wireless network from a plurality of wireless networks. A variation of the invention includes selecting a new platform from a plurality of platforms offered by the current service provider according to a service request from the wireless device. The method comprises determining a requested service associated with the wireless device, determining whether one of the plurality of wireless networks can provide the requested service, and, if one of the plurality of wireless networks can provide the requested service, choosing the one wireless network of the plurality of wireless networks. The method further involves using a variety of parameters in determining which wireless network to choose for servicing the requested service from the wireless device. These parameters include quality of services, application supported, or other business factors such as roaming agreements, traffic load and cost of services. The system comprises at least one wireless network node, a wireless device, and a plurality of wireless networks communicating with each other. Either the wireless device or network node may operate to decide based on the services the wireless device user requires on which network the user will receive service from. The network assignment is accomplished to maximize the speed, cost and efficiency of transmission.
摘要翻译：公开了一种用于选择无线网络的系统和方法。该方法涉及从多个无线网络中选择无线网络。本发明的变型包括根据来自无线设备的服务请求从当前服务提供商提供的多个平台中选择新平台。该方法包括确定与无线设备相关联的所请求的服务，确定所述多个无线网络中的一个是否能够提供所请求的服务，以及如果所述多个无线网络中的一个可以提供所请求的服务，则选择所述一个无线网络多个无线网络。该方法还涉及使用各种参数来确定从无线设备为哪个无线网络选择用于服务所请求的服务。这些参数包括服务质量，支持的应用程序或其他业务因素，如漫游协议，流量负载和服务成本。该系统包括彼此通信的至少一个无线网络节点，无线设备和多个无线网络。无线设备或网络节点可以基于无线设备用户在用户将从哪个网络接收服务所需的服务来进行操作。实现网络分配以最大限度地提高传输的速度，成本和效率。

109. 发明申请

US20080171013A1 POSACONAZOLE POLYMER CONJUGATES AND METHODS OF TREATMENT USING POSACONAZOLE AND POLYMER CONJUGATES THEREOF 失效
标题翻译：噻唑并噻唑聚合物联合方法及其用途及其聚合物联合治疗方法
公开(公告)号：US20080171013A1
公开(公告)日：2008-07-17
申请号：US12014391
申请日：2008-01-15
申请人： Hong Zhao
发明人： Hong Zhao
IPC分类号： A61K31/74 , A61K31/496 , C08G65/333
CPC分类号： A61K31/496 , A61K31/74 , A61K47/60 , C08G65/331 , C08G65/3318 , C08G65/3326 , C08G65/33317 , C08G65/33396 , C08L2203/02
摘要： Improved posaconazole-based compositions and methods of treating and preventing fungal infections, cancer or metastatic diseases are disclosed. In preferred aspects, the conjugates are PEG-posaconazole conjugates in which the PEG has a molecular weight of about 20,000 daltons.
摘要翻译：公开了基于泊沙康唑的组合物的改进和治疗和预防真菌感染，癌症或转移性疾病的方法。在优选的方面，缀合物是PEG-泊沙康唑缀合物，其中PEG具有约20,000道尔顿的分子量。

110. 发明授权

US07310792B2 Method and system for modeling variation of circuit parameters in delay calculation for timing analysis 有权
标题翻译：用于时序分析的延迟计算中电路参数变化的方法和系统
公开(公告)号：US07310792B2
公开(公告)日：2007-12-18
申请号：US11014096
申请日：2004-12-15
申请人： Nishath K. Verghese , Hong Zhao
发明人： Nishath K. Verghese , Hong Zhao
IPC分类号： G06F17/50
CPC分类号： G06F17/5031
摘要： A system, method, and computer program accurately models circuit parameter variation for delay calculation. For any given circuit parameter value, a cell is characterized at just three values in the circuit parameter range. An interpolation process generates an equation to calculate delay using the characterization data from the three circuit parameter values. This delay equation calculates the delay for any value in the circuit parameter range. Similar methodology is used to model simultaneous variation of two circuit parameters. The cell is characterized at just six circuit parameter pairs to interpolate the delay equation for any circuit parameter pair in the characterized ranges. This methodology can be extended to accommodate variation of multiple circuit parameters using similar interpolation techniques.
摘要翻译：系统，方法和计算机程序准确地对电路参数变化进行延迟计算。对于任何给定的电路参数值，单元格仅在电路参数范围内的三个值进行表征。插值过程使用来自三个电路参数值的表征数据产生计算延迟的方程式。该延迟方程计算电路参数范围内任何值的延迟。类似的方法用于模拟两个电路参数的同时变化。该单元的特征在于仅仅六个电路参数对，以在特征化范围内插值任何电路参数对的延迟方程。可以使用类似的内插技术来扩展该方法以适应多个电路参数的变化。

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