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91. 发明申请

US20050008668A1 Carbamates for the modification of rheological properties 审中-公开
标题翻译：用于改性流变性能的氨基甲酸酯
公开(公告)号：US20050008668A1
公开(公告)日：2005-01-13
申请号：US10883411
申请日：2004-07-01
申请人： Angelo Provinzano , Jurgen Meyer , Wolfgang Goertz
发明人： Angelo Provinzano , Jurgen Meyer , Wolfgang Goertz
IPC分类号： A61K8/37 , A61K8/44 , A61Q19/10 , C08G18/28 , C08G18/32 , C08G18/71 , A61K7/18 , A61K7/06 , A61K7/11 , C08G18/70
CPC分类号： C08G18/3218 , A61K8/375 , A61K8/44 , A61Q19/10 , C08G18/283 , C08G18/71
摘要： Carbamates obtainable by reacting a) at least one isocyanate of the general formula (II) and/or (IIa) (OCN—R1—NCO) (II) (R4—NCO) (IIa) b) at least one hydroxyl compound of the general formula (III) and/or (IIIa) and/or (IIIb) (R2—(R3O)n—OH) (III) HO—CH2—(CH—OH)m—CH2—OH (IIIa) R—O—[Z]b (IIIb) are described as well as their use for the modification of Theological properties of homogeneous-phase systems or hetergeneous-phase systems which contain at least one hydrophobic component.
摘要翻译：通过使a）至少一种通式（II）的异氰酸酯和/或（IIa）（OCN-R 1 -NCO）（II）（R 4 -NCO）（IIa）b）在至少一种通式（III）和/或（IIIa）和/或（IIIb）（R 2 - （R 3 O）n -OH）的羟基化合物（III）HO-CH 2 - （CH- OH）m-CH 2 -OH（IIIa）RO- [Z] b（IIIb）以及它们用于修饰含有至少一个疏水组分的均相系统或异源相系统的神学性质的用途。

92. 发明申请

US20050002874A1 Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries 有权
标题翻译：选择和使用乳酸菌减少龋齿和引起龋齿的细菌
公开(公告)号：US20050002874A1
公开(公告)日：2005-01-06
申请号：US10869185
申请日：2004-06-14
申请人： Bo Mollstam , Eamonn Connolly
发明人： Bo Mollstam , Eamonn Connolly
IPC分类号： A23C9/123 , A23G3/36 , A23G4/12 , A23L1/03 , A23L1/30 , A61K8/97 , A61K35/74 , A61P1/02 , A61Q11/00 , C12N1/00 , C12R1/225 , A61K9/68 , A61K7/18 , A61K7/28 , C12N1/20
CPC分类号： A23C9/1234 , A23C2260/25 , A23G3/366 , A23G4/12 , A23G4/123 , A23L33/135 , A23V2002/00 , A23Y2220/71 , A61K8/9706 , A61K8/99 , A61K35/747 , A61Q11/00 , C12R1/225 , Y10S435/853 , A23V2200/312 , A23V2250/206
摘要： New strains of Lactobacillus that have been selected for their capability of improved reduction the number of Streptococcus mutans in the mouth of mammals through inhibiting activity in combination with better binding to the oral mucins and dental plaque, thereby preventing, reducing or treating dental caries, and products derived from said strains, including agents for treatment or prophylaxis of caries for administration to humans.
摘要翻译：通过抑制活性与更好地结合口腔粘蛋白和牙菌斑，从而防止，减少或治疗龋齿，已经选择了其能够改善哺乳动物口腔中变形链球菌数目的能力的新菌株，衍生自所述菌株的产品，包括用于治疗或预防用于给予人的龋齿的药剂。

93. 发明授权

US6042812A Flavor systems for oral care products 失效
标题翻译：口腔护理产品的香味系统
公开(公告)号：US6042812A
公开(公告)日：2000-03-28
申请号：US756671
申请日：1996-11-26
申请人： Lowell Alan Sanker , James Grigg Upson
发明人： Lowell Alan Sanker , James Grigg Upson
IPC分类号： A61K8/21 , A61K8/22 , A61K8/24 , A61K8/92 , A61Q11/00 , A61K7/16 , A61K7/18 , A61K7/20 , A61K7/26
CPC分类号： A61K8/22 , A61K8/21 , A61K8/24 , A61K8/922 , A61Q11/00
摘要： Disclosed are oral compositions comprising a total flavor system and one or more aqueous carriers, wherein the oral composition is a dentifrice or a mouthrinse. The total flavor system comprises a traditional oral care flavor system and a dairy-creme component.
摘要翻译：公开了包含总风味体系和一种或多种含水载体的口服组合物，其中口腔组合物是洁齿剂或漱口水。总风味系统包括传统的口腔护理风味系统和乳制品组分。

94. 发明授权

US5989524A Silica compatible with flavors, process for its preparation and dentifrice compositions containing it 失效
标题翻译：与香料兼容的二氧化硅，其制备方法和含有它的洁齿剂组合物
公开(公告)号：US5989524A
公开(公告)日：1999-11-23
申请号：US896349
申请日：1997-07-18
申请人： Adrien Dromard , Jean-Francois Viot
发明人： Adrien Dromard , Jean-Francois Viot
IPC分类号： A61K8/00 , A61K8/25 , A61K8/33 , A61K8/36 , A61K8/368 , A61K8/40 , A61K8/86 , A61K8/89 , A61Q11/00 , C01B33/12 , C08K9/00 , C08L83/06 , C08L101/00 , C09K3/00 , C09K3/14 , A61K7/16 , A61K7/18
CPC分类号： A61K8/25 , A61Q11/00
摘要： Silica compatible with flavors, exhibiting, at an RP/DA abrasivity lower than or equal to 10, a compatibility with flavors which is higher than 10% and, at an RP/DA abrasivity higher than 10, a compatibility with flavors of at least 30%. Process for the preparation of flavor-compatible silica by treating the surface of a silica originating from the reaction of an alkali metal silicate with an inorganic or organic acidic agent, the silica being in dry form or in an aqueous suspension, with the aid of an organic compound capable of developing hydrogen bonds or ionic bonds with, respectively, the Si--OH silanol groups or the SiO.sup.- anionic groups at the surface of the said silica to be treated, the said treated silica being subsequently, if necessary, isolated and/or washed and/or dried. Use in dentifrice compositions and dentifrice compositions including the said silica.
摘要翻译：与风味相容的二氧化硅，以低于或等于10的RP / DA磨损性表现出与高于10％的风味的相容性，并且以高于10的RP / DA磨损性，与至少30的风味相容％。通过处理来自碱金属硅酸盐与无机或有机酸性试剂的反应的二氧化硅的表面，二氧化硅为干式或水悬浮液，借助于能够分别与待处理的所述二氧化硅表面上的Si-OH硅烷醇基团或SiO-阴离子基团发生氢键或离子键的有机化合物，如果需要，所述经处理的二氧化硅如果需要，分离和/ 或洗涤和/或干燥。用于洁牙剂组合物和洁齿剂组合物，包括所述二氧化硅。

95. 发明授权

US5980869A Dual phase oral compositions comprising a plant extract from the Ericaceae family 失效
标题翻译：双相口服组合物，其包含来自埃里克森科（Ericaceae）家族的植物提取物
公开(公告)号：US5980869A
公开(公告)日：1999-11-09
申请号：US848627
申请日：1997-04-28
申请人： Lowell Alan Sanker , Stephen James Nilsen
发明人： Lowell Alan Sanker , Stephen James Nilsen
IPC分类号： A61K8/19 , A61K8/97 , A61Q11/00 , A61K7/26 , A61K7/16 , A61K7/18
CPC分类号： A61Q11/00 , A61K8/19 , A61K8/97 , A61K2800/88
摘要： The present invention relates to an oral formulation contained in physically separated compartments of a suitable dispenser, comprising a first oral composition comprising from about 0.5% to about 50% of an alkali metal bicarbonate salt and from about 50% to about 99.5% of one or more aqueous carriers; and a second oral composition comprising a safe and effective amount of a plant species of the Ericaceae family or its extract and from about 40% to about 99.9% of one or more aqueous carriers.
摘要翻译：本发明涉及包含在适当分配器的物理分离的隔室中的口服制剂，其包含第一口服组合物，其包含约0.5％至约50％的碱金属碳酸氢盐和约50％至约99.5％的一种或多种更多含水载体; 以及第二口服组合物，其包含安全有效量的埃里卡捷科（Ericaceae）家族或其提取物的植物物种和约40％至约99.9％的一种或多种含水载体。

96. 发明授权

US5908612A Oral care compositions comprising liquid polyoxyalkylene compounds as solubilizers/gelling agents 失效
标题翻译：包含液体聚氧化烯化合物作为增溶剂/胶凝剂的口腔护理组合物
公开(公告)号：US5908612A
公开(公告)日：1999-06-01
申请号：US775328
申请日：1996-12-31
申请人： James S. Dailey , Jay G. Otten , Jay Amarasekara , Sridhar Gopalkrishnan
发明人： James S. Dailey , Jay G. Otten , Jay Amarasekara , Sridhar Gopalkrishnan
IPC分类号： A61K8/22 , A61K8/86 , A61K8/90 , A61Q11/00 , A61K7/16 , A61K7/18 , A61K7/22
CPC分类号： A61Q11/00 , A61K8/22 , A61K8/86 , A61K8/90
摘要： The present invention relates to oral care compositions comprising Liquid Polyoxyalkylene Compounds as Solubilizers/Gelling Agents.
摘要翻译：本发明涉及包含液体聚氧化烯化合物作为增溶剂/胶凝剂的口腔护理组合物。

97. 发明授权

US5874065A Oral anti-acid paste and methods of use 失效
标题翻译：口服抗酸膏及使用方法
公开(公告)号：US5874065A
公开(公告)日：1999-02-23
申请号：US882850
申请日：1997-06-26
申请人： Alan A. Pardini
发明人： Alan A. Pardini
IPC分类号： A61K8/19 , A61K8/21 , A61K8/22 , A61K8/26 , A61Q11/00 , A61K7/16 , A61K7/18 , A61K33/06 , A61K33/16
CPC分类号： A61Q11/00 , A61K8/19 , A61K8/21 , A61K8/26
摘要： The invention describes an oral anti-acid paste comprising anti-acid compound in a slow releasing carrier medium which disperses the anti-acid, and releases the anti-acid from the paste upon contact with the aqueous media such as saliva. The paste can be used by placement in the mouth for slow release of the anti-acid into the saliva thereby contacting the mucosa of the esophagus to inhibit irritation to the mucosa due to excess acid.
摘要翻译：本发明描述了一种在缓释载体介质中包含抗酸化合物的口服抗酸膏，其分散抗酸，并在与含水介质如唾液接触时从膏中释放出抗酸。该糊剂可以通过放置在口中用于将抗酸缓慢释放到唾液中，从而接触食道粘膜以抑制由于过量的酸对粘膜的刺激。

98. 发明授权

US5863521A Liquid heteric-block polyoxyalkylene compounds having improved flowability characteristics 失效
标题翻译：具有改善的流动性特性的液态杂多嵌段聚氧化烯化合物
公开(公告)号：US5863521A
公开(公告)日：1999-01-26
申请号：US775235
申请日：1996-12-30
申请人： Anthony G. Schaefer , Sridhar Gopalkrishnan , Jay G. Otten , Richard J. Holland
发明人： Anthony G. Schaefer , Sridhar Gopalkrishnan , Jay G. Otten , Richard J. Holland
IPC分类号： A61K8/22 , A61K8/90 , A61Q11/00 , A61Q19/10 , C08G65/26 , A61K7/16 , A61K7/18 , A61K7/20
CPC分类号： C08G65/26 , A61K8/22 , A61K8/90 , A61Q11/00 , A61Q19/10
摘要： The present invention relates to liquid polyoxyalkylene compounds having improved flowability characteristics useful in a variety of industrial and personal care applications.
摘要翻译：本发明涉及具有改进的可用于各种工业和个人护理应用的流动性特性的液体聚氧化烯化合物。

99. 发明授权

US5858333A Two-part oral products and methods of using same to remineralize teeth 有权
标题翻译：两部分口服产品及其使用方法使牙齿再矿化
公开(公告)号：US5858333A
公开(公告)日：1999-01-12
申请号：US131314
申请日：1998-08-07
申请人： Anthony E. Winston , Norman Usen
发明人： Anthony E. Winston , Norman Usen
IPC分类号： A61K8/19 , A61K8/24 , A61K9/00 , A61Q11/00 , A61K7/16 , A61K7/18 , A61K9/65
CPC分类号： A61Q11/00 , A61K8/0237 , A61K8/19 , A61K8/24 , A61K9/0063 , A61K2800/88
摘要： A two-part oral product capable of remineralizing subsurface lesions and/or mineralizing exposed dentinal tubules in teeth is composed of cationic and anionic discrete parts. The cationic discrete part contains at least one water-soluble calcium salt and, preferably, at least one non-toxic, water-soluble salt of a divalent metal other than calcium, and a first pharmaceutically acceptable carrier. The anionic discrete part contains at least one water-soluble phosphate salt and, preferably, at least one water-soluble fluoride salt, and a second pharmaceutically carrier. Preferably, one of the carriers is an aqueous carrier and the other of the carriers is a non-aqueous carrier. The cationic and anionic parts are simultaneously released from the product upon mixing of the product with water and/or saliva to form the mixed aqueous solution. In this way, calcium ions released by the calcium salt and phosphate ions released by the phosphate salt are simultaneously delivered to the tooth surfaces by the solution. To effect subsurface remineralization and/or mineralization, the parts are mixed together to form the mixed aqueous solution, and the solution is then promptly applied to the teeth for a period of time sufficient to allow calcium ions and phosphate ions to diffuse through the tooth surface to the subsurface, where the ions react to form an insoluble precipitate onto the lesion and/or tubule, thereby remineralizing such lesion and/or mineralizing such tubule.
摘要翻译：能够再次矿化地下病变和/或使牙齿中暴露的牙质小管矿化的两部分口服产品由阳离子和阴离子分立部分组成。阳离子分散部分含有至少一种水溶性钙盐，优选至少一种无钙水溶性的钙以外的二价金属的盐和第一药学上可接受的载体。阴离子离子部分含有至少一种水溶性磷酸盐，优选至少一种水溶性氟化物盐和第二种药物载体。优选地，载体之一是水性载体，另一种载体是非水载体。当产品与水和/或唾液混合时，阳离子和阴离子部分同时从产物中释放出来以形成混合的水溶液。以这种方式，由磷酸盐释放的钙盐和磷酸根离子释放的钙离子被溶液同时输送到牙齿表面。为了实现地下再矿化和/或矿化，将这些部分混合在一起以形成混合的水溶液，然后将溶液迅速施加到牙齿上一段足以允许钙离子和磷酸根离子通过牙齿表面扩散的时间到地下，其中离子反应以在病变和/或小管上形成不溶性沉淀物，从而使这种损伤和/或矿化这种小管再矿化。

100. 发明授权

US5849267A Stable desensitizing antitartar dentifrice 失效
标题翻译：稳定的脱敏剂antitartar洁牙剂
公开(公告)号：US5849267A
公开(公告)日：1998-12-15
申请号：US859506
申请日：1997-05-20
申请人： Michael A. Collins , Richard J. Crawford , Donald W. Clipper
发明人： Michael A. Collins , Richard J. Crawford , Donald W. Clipper
IPC分类号： A61K8/19 , A61K8/24 , A61K8/55 , A61K8/73 , A61K8/81 , A61Q11/00 , A61K7/16 , A61K7/18
CPC分类号： A61K8/24 , A61K8/19 , A61K8/55 , A61K8/73 , A61K8/731 , A61K8/8164 , A61Q11/00 , A61K2800/5424 , A61K2800/594
摘要： A desensitizing anti-tartar dentifrice of low stringiness upon extrusion from a tube or other container onto a toothbrush is provided which also retains desirable cream or gel consistency without becoming thick and difficult to extrude and retains phase integrity without substantial separation, which contains polyphosphate or phosphono compound anti-tartar agent and potassium salt tooth pain inhibitor and in which the gelling agent is a mixture of alkali metal carboxymethyl cellulose, (CMC) and xanthan, wherein the CMC contains about 1.0 to 1.5 carboxymethyl groups per anhydroglycose unit.
摘要翻译：提供从管或其他容器挤出到牙刷上时具有低拉丝性的脱敏抗牙垢洁牙剂，其还保留所需的乳膏或凝胶稠度，而不变厚并且难以挤出并保持相位完整性而没有基本分离，其含有多磷酸盐或膦酰基复合抗牙垢剂和钾盐牙齿疼痛抑制剂，其中胶凝剂是碱金属羧甲基纤维素（CMC）和黄原胶的混合物，其中CMC含有每个脱水糖苷单元约1.0-1.5个羧甲基。

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