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    • 99. 发明申请
    • Method for treating tumor cells resulting in minimal liver toxicity
    • 治疗肿瘤细胞导致肝毒性最小的方法
    • US20070010454A1
    • 2007-01-11
    • US11456026
    • 2006-07-06
    • Majid Moridani
    • Majid Moridani
    • A61K38/05A61K31/22A01N31/08
    • A61K38/063A61K31/085A61K31/22A61K47/64A61K47/67B82Y5/00
    • A method for treating tumor cells resulting in minimal liver toxicity. An illustrative embodiment includes a method for inhibiting growth of a tumor in a mammal, comprising contacting tumor cells which have tyrosinase activity or P450 activity with 4-t-butoxyphenol, a cytotoxic phenolic composition administered at a dose sufficient to induce tumor cell death with minimal toxicity to the liver. Another illustrative embodiment may be a method for inhibiting growth of a tumor in a mammal, comprising contacting tumor cells which have tyrosinase activity or P450 activity with 4-n-hexyloxyphenol, a cytotoxic phenolic composition administered at a dose sufficient to induce tumor cell death with minimal toxicity to the liver.
    • 一种治疗肿瘤细胞导致肝毒性最小的方法。 说明性的实施方案包括抑制哺乳动物肿瘤生长的方法,包括将具有酪氨酸酶活性或P450活性的肿瘤细胞与4-叔丁氧基苯酚接触,以足以诱导肿瘤细胞死亡的剂量施用的细胞毒性酚类组合物 对肝脏有毒性 另一个说明性的实施方案可以是抑制哺乳动物肿瘤生长的方法,包括将具有酪氨酸酶活性或P450活性的肿瘤细胞与4-正己氧基苯酚接触,以足以诱导肿瘤细胞死亡的剂量施用的细胞毒性酚类组合物 对肝脏的毒性最小。