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91. 发明申请

US20070134332A1 Polymer particles for delivery of macromolecules and methods of use 审中-公开
标题翻译：用于递送大分子的聚合物颗粒和使用方法
公开(公告)号：US20070134332A1
公开(公告)日：2007-06-14
申请号：US11603660
申请日：2006-11-21
申请人： William Turnell , Geoffrey Landis , Zaza Gomurashvili , Hong Li , Kristin DeFife , Vassil Vassilev , Yumin Yuan
发明人： William Turnell , Geoffrey Landis , Zaza Gomurashvili , Hong Li , Kristin DeFife , Vassil Vassilev , Yumin Yuan
IPC分类号： A61K48/00 , A61K38/28 , C08F20/00 , A61K9/14
CPC分类号： A61K9/167 , A61K9/1075 , A61K9/5146 , A61K38/28 , A61K47/59 , A61K47/593 , A61K47/595 , C08L77/12
摘要： The present invention provides biodegradable polymer particle delivery compositions for delivery of macromolecular biologics, for example in crystal form, based on polymers, such as polyester amide (PEA), polyester urethane (PEUR), and polyester urea (PEU) polymers, which contain amino acids in the polymer. The polymer particle delivery compositions can be formulated either as a liquid dispersion or a lyophilized powder of polymer particles containing bound water molecules with the macromolecular biologics, for example insulin, dispersed in the particles. Bioactive agents, such as drugs, polypeptides, and polynucleotides can also be delivered by using particles sized for local, oral, mucosal or circulatory delivery. Methods of delivering a macromolecular biologic with substantial native activity to a subject, for example orally, are also included.
摘要翻译：本发明提供了生物可降解的聚合物颗粒递送组合物，其用于输送大分子生物制剂，例如以晶体形式，基于聚合物，例如含有氨基的聚酯酰胺（PEA），聚酯聚氨酯（PEUR）和聚酯尿素（PEU）聚合物聚合物中的酸。聚合物颗粒递送组合物可以配制成分散在颗粒中的液体分散体或含有结合水分子的聚合物颗粒与大分子生物制剂例如胰岛素的冻干粉末。生物活性剂，例如药物，多肽和多核苷酸也可以通过使用尺寸适于局部，口服，粘膜或循环递送的颗粒递送。还可以包括向受试者例如口服递送具有大量天然活性的大分子生物学方法。

92. 发明申请

US20070116958A1 Conductive endless belt 有权
标题翻译：导电环形带
公开(公告)号：US20070116958A1
公开(公告)日：2007-05-24
申请号：US11595934
申请日：2006-11-13
申请人： Takahiro Suzuki , Toshiyuki Osaki , Kunio Machida , Yoichi Nishimuro
发明人： Takahiro Suzuki , Toshiyuki Osaki , Kunio Machida , Yoichi Nishimuro
IPC分类号： B32B27/36 , B32B27/00
CPC分类号： C08L67/025 , C08K3/04 , C08L77/12 , G03G15/0131 , G03G15/162 , Y10T428/13 , Y10T428/1352 , Y10T428/1386 , Y10T428/139 , Y10T428/31504 , Y10T428/31786 , C08L2666/20
摘要： A conductive endless belt is composed of elastomer polyester with a crystalline melting point at 210° C. or more, or mainly composed of the elastomer polyester, and a thermoplastic polyester-based resin at 49 wt % or less, added a polymer ion conductive agent and a carbon black. The conductive endless belt. satisfies elastic modulus, creep resistance, bending durability, etc. and has decreased volume resistance variation and environment dependency while having superior durability, glossiness and setting performance that satisfying desired performance, without causing problems such as offset image.
摘要翻译：导电性环形带由结晶熔点在210℃以上或由弹性体聚酯构成的弹性体聚酯和49重量％以下的热塑性聚酯类树脂构成，加入聚合物离子导电剂和炭黑。导电环形带。满足弹性模量，抗蠕变性，弯曲耐久性等，并且具有降低的体积电阻变化和环境依赖性，同时具有满足期望性能的优异的耐久性，光泽度和凝固性能，而不会引起诸如偏移图像的问题。

93. 发明申请

US20070116666A1 Methods and compositions for reducing or eliminating post-surgical adhesion formation 审中-公开
公开(公告)号：US20070116666A1
公开(公告)日：2007-05-24
申请号：US11652730
申请日：2007-01-12
申请人： Daniel Cohn , Eli Pines , Anna Hotovely
发明人： Daniel Cohn , Eli Pines , Anna Hotovely
IPC分类号： A61K31/785 , A61K31/765 , C08F20/00
CPC分类号： C08G69/44 , A61K31/765 , A61K31/77 , A61K31/785 , A61L31/06 , C08G63/08 , C08G63/664 , C08L77/12 , C08L67/04 , C08L67/025
摘要： The present invention relates to a method for reducing adhesions associated with post-operative surgery. The present method comprises administering or affixing a polymeric composition preferably comprising chain extended, coupled or crosslinked polyester/poly(oxyalkylene) ABA triblocks or AB diblocks having favorable EO/LA ratios to a site in the body which has been subjected to trauma, e.g. by surgery, excision or inflammatory disease. In the present invention, the polymeric material provides a barrier to prevent or reduce the extent of adhesions forming.

94. 发明授权

US07214414B2 Biodegradable polymer blends for use in making films, sheets and other articles of manufacture 有权
标题翻译：可生物降解的聚合物共混物，用于制造薄膜，片材和其他制品
公开(公告)号：US07214414B2
公开(公告)日：2007-05-08
申请号：US11103999
申请日：2005-04-12
申请人： Kishan Khemani , Harald Schmidt , Simon Hodson
发明人： Kishan Khemani , Harald Schmidt , Simon Hodson
IPC分类号： C08B30/00 , C08L5/00 , C08L99/00
CPC分类号： C08L77/12 , C08L3/02 , C08L67/02 , C08L67/03 , C08L67/04 , Y10T428/1307 , Y10T428/1334 , Y10T428/1352 , C08L67/00 , C08L2666/02 , C08L91/06 , C08L2666/18
摘要： Biodegradable polymer blends suitable for laminate coatings, wraps and other packaging materials are manufactured from a blend of suitable biodegradable polymers, such as at least one “hard” biopolymer and at least one “soft” biopolymer. “Hard” biopolymers tend to be more brittle and rigid and typically have a glass transition temperature greater than about 10° C. “Soft” biopolymers tend to be more flexible and pliable and typically have a glass transition temperature less than about 0° C. While hard and soft polymers each possess certain intrinsic benefits, certain blends of hard and soft polymers have been discovered which possess synergistic properties superior to those of either hard or soft polymers by themselves. Biodegradable polymers include polyesters, polyesteramides, polyesterurethanes, thermoplastic starch, and other natural polymers. The polymer blends may optionally include an inorganic filler. Films and sheets made from the polymer blends may be textured so as to increase the bulk hand feel. Wraps will typically be manufactured to have good “dead-fold” properties so as to remain in a wrapped position and not spring back to an “unwrapped” form.
摘要翻译：适用于层压涂层，包装和其他包装材料的可生物降解聚合物共混物由合适的可生物降解的聚合物如至少一种“硬”生物聚合物和至少一种“软”生物聚合物的混合物制成。 “硬”生物聚合物倾向于更脆和刚性，并且通常具有大于约10℃的玻璃化转变温度。“软”生物聚合物倾向于更柔软和柔韧，并且通常具有小于约0℃的玻璃化转变温度。虽然硬和软聚合物各自具有某些固有的优点，但已经发现了硬和软聚合物的某些共混物，其本身具有优于硬聚合物或软聚合物的协同性质。可生物降解的聚合物包括聚酯，聚酯酰胺，聚酯氨酯，热塑性淀粉和其他天然聚合物。聚合物共混物可任选地包括无机填料。由聚合物共混物制成的薄膜和薄片可以是纹理化的，以便增加手感。通常将制造包装以具有良好的“折叠”性质，以便保持在包裹位置并且不弹回到“展开”形式。

95. 发明申请

US20070077272A1 Solid polymer delivery compositions and methods for use thereof 有权
标题翻译：固体聚合物输送组合物及其使用方法
公开(公告)号：US20070077272A1
公开(公告)日：2007-04-05
申请号：US11525491
申请日：2006-09-21
申请人： Hong Li , William Turnell , Yumin Yuan , Geoffrey Landis , Ryan Knoy
发明人： Hong Li , William Turnell , Yumin Yuan , Geoffrey Landis , Ryan Knoy
IPC分类号： A61K48/00 , A61K39/395 , C08F20/00 , A61F2/02
CPC分类号： C08G69/44 , A61K9/0024 , A61K47/34 , A61L27/34 , A61L31/10 , C08L77/12 , C08L2666/02
摘要： The present invention provides an implantable solid polymer delivery composition that can be formulated to release a bioactive agent to an interior body site at a controlled rate over an extended period of time by adjusting the various components of the composition. The controlled delivery of the composition avoids an initial drug spike, resulting in a smooth delivery profile over time. Polymer layers in the composition can be porous and are both biodegradable in water and body enzymes and biocompatible. Methods of making the implantable solid polymer compositions and methods of delivering a bioactive agent at a controlled rate to an interior body site are also provided.
摘要翻译：本发明提供了一种可植入的固体聚合物递送组合物，其可通过调节组合物的各种成分而配制成在长时间内以受控的速率将生物活性剂释放到内部身体部位。组合物的受控输送避免了初始药物尖峰，导致随着时间的顺利递送。组合物中的聚合物层可以是多孔的，并且在水和身体酶中都是可生物降解的并且是生物相容的。还提供了制造可植入固体聚合物组合物的方法和将受控速率递送至内部身体部位的生物活性剂的方法。

96. 发明授权

US07176251B1 Biodegradable polymeric compositions comprising starch and a thermoplastic polymer 有权
公开(公告)号：US07176251B1
公开(公告)日：2007-02-13
申请号：US09297733
申请日：1997-11-05
申请人： Catia Bastioli , Vittorio Bellotti , Gian Domenico Cella , Luciano Del Giudice , Sandro Montino , Gabriele Perego
发明人： Catia Bastioli , Vittorio Bellotti , Gian Domenico Cella , Luciano Del Giudice , Sandro Montino , Gabriele Perego
IPC分类号： C08L3/00 , C08K5/04 , C08K5/10 , C07C57/13 , C07C67/08
CPC分类号： C08J5/18 , C08G18/0895 , C08G18/4277 , C08G2230/00 , C08J2303/02 , C08J2367/02 , C08J2367/04 , C08K5/0008 , C08K5/10 , C08K5/103 , C08L3/02 , C08L67/02 , C08L67/04 , C08L75/06 , C08L77/00 , C08L77/06 , C08L77/12 , C08L101/00 , C08L2201/06 , C08L2666/02 , C08L2666/26 , C08L2666/18
摘要： The present invention provides polymeric compositions containing thermoplastic starch and a thermoplastic polymer incompatible with starch, in which the starch constitutes the dispersed phase and the thermoplastic polymer constitutes the continuous phase, selected: A) from compositions comprising an agent with an interfacial effect selected from esters of polyols with mono- or polycarboxylic acids with dissociation constants within certain limits, the esters having specific values of the hydrophilic/lipophilic balance index HLB or being amongst the non-ionic surfactants which are soluble in water but cannot significantly be extracted by water from the compositions which contain them; B) from compositions wherein the thermoplastic polymer is an aliphatic or aliphatic-aromatic copolyester wherein the ratio (R) between the average viscometric molecular weight and the melt index is greater than 25,000 and C) from compositions wherein the thermoplastic polymer is selected from aliphatic-aromatic copolyesters, polyester-amides, polyester-esters, polyester-ether-amides, polyester-urethanes and polyester-ureas and wherein the compositions are obtained by extrusion of the component maintaining a water content during the mixing stage from 1 to 5% by weight.

97. 发明申请

US20070031672A1 Wire-coating composition based on new polyester amide imides and polyester amides 审中-公开
标题翻译：基于新型聚酰胺酰亚胺和聚酰胺的线涂组合物
公开(公告)号：US20070031672A1
公开(公告)日：2007-02-08
申请号：US11499060
申请日：2006-08-04
申请人： Frank-Rainer Boehm , Michael Herm
发明人： Frank-Rainer Boehm , Michael Herm
IPC分类号： D02G3/00
CPC分类号： C09D177/12 , C08G18/6438 , C08L67/00 , C08L75/04 , C08L77/12 , C08L79/08 , C09D179/08 , H01B3/305 , H01B3/306 , H01B3/421 , Y10T428/2933 , C08L2666/20 , C08L2666/18
摘要： Wire-coating composition containing resins with nucleophilic groups as well as possibly amide group-containing resins which are capable of crosslinking with one another, comprising (A) 5 to 95% by weight of at least one resin with nucleophilic groups selected from the group consisting of OH, NHR, SH, carboxylate and CH-acidic groups, (B) 0 to 70% by weight of at least one amide group-containing resin and (C) 5 to 95% by weight of at least one organic solvent, wherein the resins of either component (A) or component (B) contain α-carboxy-β-oxocycloalkyl carboxylic acid amide groups and the percent by weight of (A)-(C) adds up to 100 percent. The wire-coating compositions according to the invention allow a significant increase in the enamelling speed without losing the positive properties of standard wire enamels.
摘要翻译：含有具有亲核基团的树脂以及可能含有酰胺基的树脂的能够彼此交联的线涂组合物包含（A）5至95重量％的至少一种具有亲核基团的树脂，所述亲核基团选自的OH，NHR，SH，羧酸酯和CH-酸性基团，（B）0至70重量％的至少一种含酰胺基的树脂和（C）5至95重量％的至少一种有机溶剂，其中组分（A）或组分（B）的树脂含有α-羧基-β-氧代环烷基羧酸酰胺基团，（A） - （C）的重量百分数可达100％。根据本发明的线涂组合物允许显着增加搪瓷速度，而不会损失标准丝搪瓷的阳性。

98. 发明申请

US20070010620A1 Polycarbonate resin composition and molded articles of the same 有权
标题翻译：聚碳酸酯树脂组合物及其模塑制品
公开(公告)号：US20070010620A1
公开(公告)日：2007-01-11
申请号：US11474031
申请日：2006-06-23
申请人： Kyung Seo , Kyung Kim , Sung Min , Bong Lee
发明人： Kyung Seo , Kyung Kim , Sung Min , Bong Lee
IPC分类号： C08L51/00
CPC分类号： C08L69/00 , C08L51/04 , C08L67/03 , C08L77/12 , C08L2666/02
摘要： A polycarbonate composition and its use as a molded article and as housing or a part of electronic device are disclosed. The polycarbonate composition includes a polycarbonate resin, a liquid crystalline polymer resin, and a core-shell graft copolymer. The polycarbonate compositions described herein have improved fatigue strength and impact strength.
摘要翻译：公开了一种聚碳酸酯组合物及其作为模制品和作为壳体或电子器件的一部分的用途。聚碳酸酯组合物包括聚碳酸酯树脂，液晶聚合物树脂和芯 - 壳接枝共聚物。本文所述的聚碳酸酯组合物具有改善的疲劳强度和冲击强度。

99. 发明授权

US07144632B2 Aliphatic-aromatic polyetherester compositions, articles, films, coating and laminates and processes for producing same 有权
标题翻译：脂肪族 - 芳族聚醚酯组合物，制品，薄膜，涂层和层压材料及其制造方法
公开(公告)号：US07144632B2
公开(公告)日：2006-12-05
申请号：US10459161
申请日：2003-06-11
申请人： Richard Allen Hayes
发明人： Richard Allen Hayes
IPC分类号： B32B27/00
CPC分类号： B32B27/06 , B32B27/28 , B32B27/36 , B32B2439/70 , C08G63/6886 , C08L3/02 , C08L67/00 , C08L67/025 , C08L67/04 , C08L69/00 , C08L77/12 , C09D167/00 , D21H19/28 , D21H27/10 , Y10T428/31504 , Y10T428/31565 , Y10T428/31786 , Y10T442/2139 , Y10T442/2221 , C08L2666/26 , C08L2666/14
摘要： Aliphatic-aromatic polyetherester compositions, articles made from the aliphatic-aromatic polyetherester compositions, and processes for producing the aliphatic-aromatic polyetherester compositions and articles are provided. Articles that can be made from the aliphatic-aromatic polyetherester compositions include films, coatings and laminates. Some of the compositions and articles are biocompostable. The films can further be used to form shaped articles such as sheets, food packaging such as sandwich wraps, thermoformed containers, and coatings for, for example, films and other substrates. The aliphatic-aromatic polyetheresters are based on copolyesters produced from a mixture of aromatic dicarboxylic acids, aliphatic dicarboxylic acids, poly(alkyene ether) glycols, and glycols.
摘要翻译：提供脂肪族 - 芳族聚醚酯组合物，由脂族 - 芳族聚醚酯组合物制成的制品，以及制备脂族 - 芳族聚醚酯组合物和制品的方法。可以由脂族 - 芳族聚醚酯组合物制成的制品包括薄膜，涂料和层压材料。一些组合物和制品是可生物相容的。这些膜还可用于形成诸如片材的成形制品，诸如夹心包装的食品包装，热成型容器以及用于例如薄膜和其它基材的涂层。脂族 - 芳族聚醚酯基于由芳族二羧酸，脂族二羧酸，聚（烷基醚）二醇和二醇的混合物制备的共聚酯。

100. 发明申请

US20060235400A1 Bone plate 有权
标题翻译：骨板
公开(公告)号：US20060235400A1
公开(公告)日：2006-10-19
申请号：US11361942
申请日：2006-02-24
申请人： Rolf Schneider
发明人： Rolf Schneider
IPC分类号： A61F2/30
CPC分类号： A61B17/8033 , A61B17/80 , A61B17/8052 , A61B17/8057 , A61L27/18 , A61L31/06 , A61L2430/02 , C08L77/12 , C08L71/00
摘要： A bone plate has an underside on the side of the bone, an upper side and a plurality of holes in the plate connecting the underside with the upper side, with a central hole axis. At least one of these holes in the plate has an internal jacket surface that tapers towards the underside, while the internal jacket surface has N≧3 recesses which extend radially away from the axis of the hole.
摘要翻译：骨板在骨的侧面具有下侧，板的上侧和多个孔，其连接下侧与上侧，具有中心孔轴。板中的这些孔中的至少一个具有朝向下侧逐渐变细的内部护套表面，而内部护套表面具有径向远离孔的轴线延伸的N> 3个凹部。

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