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91. 发明申请

US20130096503A1 ACCUMULATOR FOR IMPLANTABLE INFUSION DEVICE 有权
标题翻译：用于可植入输注装置的累积器
公开(公告)号：US20130096503A1
公开(公告)日：2013-04-18
申请号：US13275736
申请日：2011-10-18
申请人： James M. Haase , Ronald L. Mezera , John M. Gray , Nicholas R. Whitehead , Jeffrey P. Bodner , Brian C. Egan
发明人： James M. Haase , Ronald L. Mezera , John M. Gray , Nicholas R. Whitehead , Jeffrey P. Bodner , Brian C. Egan
IPC分类号： A61M5/145 , A61M5/142
CPC分类号： A61M5/14276 , A61M5/16809 , A61M2205/3331 , A61M2205/3362 , A61M2205/8212 , A61M2206/22
摘要： An accumulator is employed in an implantable infusion device to provide compliance in the flow path of the device. The accumulator may act to increase the pumping accuracy and repeatability while simultaneously reducing the energy requirements of the device. In one example, the accumulator is arranged at the outlet of a fluid delivery pump of the infusion device. The accumulator includes a cover and a diaphragm biased away from the cover and configured to deflect toward the cover under pressure generated by the therapeutic agent in a flow path of the infusion device. The cover of the accumulator is configured to withstand the pressure generated by the therapeutic agent in the flow path without deforming.
摘要翻译：在可植入输注装置中采用蓄能器以在装置的流动路径中提供顺应性。蓄能器可以用于增加泵送精度和重复性，同时降低装置的能量需求。在一个示例中，蓄能器布置在输液装置的流体输送泵的出口处。蓄能器包括盖子和偏离盖子的隔膜，并被构造成在灌注装置的流动路径中由治疗剂产生的压力下向盖子偏转。蓄能器的盖构造成能够承受流路中治疗剂产生的压力而不变形。

92. 发明申请

US20120209193A1 PATCH-SIZED FLUID DELIVERY SYSTEMS AND METHODS 审中-公开
公开(公告)号：US20120209193A1
公开(公告)日：2012-08-16
申请号：US12395000
申请日：2009-02-27
申请人： Larry B. Gray
发明人： Larry B. Gray
IPC分类号： A61M5/142 , B23P11/00
CPC分类号： A61M5/5086 , A61B5/0024 , A61B5/1427 , A61B5/6833 , A61B2560/0412 , A61J1/20 , A61M5/1413 , A61M5/142 , A61M5/14212 , A61M5/14216 , A61M5/14224 , A61M5/14244 , A61M5/14248 , A61M5/1452 , A61M5/14586 , A61M5/158 , A61M5/162 , A61M5/168 , A61M5/16804 , A61M5/16809 , A61M5/16813 , A61M5/16831 , A61M5/16886 , A61M5/172 , A61M5/1723 , A61M5/365 , A61M2005/1402 , A61M2005/14208 , A61M2005/14252 , A61M2005/14268 , A61M2005/14506 , A61M2005/1583 , A61M2005/1585 , A61M2005/1586 , A61M2005/16863 , A61M2205/0266 , A61M2205/0294 , A61M2205/04 , A61M2205/16 , A61M2205/18 , A61M2205/3303 , A61M2205/3331 , A61M2205/3337 , A61M2205/3368 , A61M2205/3375 , A61M2205/3379 , A61M2205/3523 , A61M2205/3546 , A61M2205/3569 , A61M2205/3576 , A61M2205/3592 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/8206 , A61M2205/8237 , A61M2206/22 , A61M2207/00 , A61M2209/045 , A61M2230/201 , F04B43/02 , G01F22/00 , G05B23/02 , G05D7/0647 , G05D7/0676 , G08C17/02 , H04B7/2609 , Y10T29/49236 , Y10T29/494 , Y10T29/49412 , Y10T29/49826 , Y10T29/49828
摘要： A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

93. 发明申请

US20120209189A1 ADHESIVE AND PERIPHERAL SYSTEMS AND METHODS FOR MEDICAL DEVICES 有权
公开(公告)号：US20120209189A1
公开(公告)日：2012-08-16
申请号：US12395098
申请日：2009-02-27
申请人： Larry B. Gray , Eric Yeaton
发明人： Larry B. Gray , Eric Yeaton
IPC分类号： A61M5/158
CPC分类号： A61M5/5086 , A61B5/0024 , A61B5/1427 , A61B5/6833 , A61B2560/0412 , A61J1/20 , A61M5/1413 , A61M5/142 , A61M5/14212 , A61M5/14216 , A61M5/14224 , A61M5/14244 , A61M5/14248 , A61M5/1452 , A61M5/14586 , A61M5/158 , A61M5/162 , A61M5/168 , A61M5/16804 , A61M5/16809 , A61M5/16813 , A61M5/16831 , A61M5/16886 , A61M5/172 , A61M5/1723 , A61M5/365 , A61M2005/1402 , A61M2005/14208 , A61M2005/14252 , A61M2005/14268 , A61M2005/14506 , A61M2005/1583 , A61M2005/1585 , A61M2005/1586 , A61M2005/16863 , A61M2205/0266 , A61M2205/0294 , A61M2205/04 , A61M2205/16 , A61M2205/18 , A61M2205/3303 , A61M2205/3331 , A61M2205/3337 , A61M2205/3368 , A61M2205/3375 , A61M2205/3379 , A61M2205/3523 , A61M2205/3546 , A61M2205/3569 , A61M2205/3576 , A61M2205/3592 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/8206 , A61M2205/8237 , A61M2206/22 , A61M2207/00 , A61M2209/045 , A61M2230/201 , G01F22/00 , G05B23/02 , G05D7/0647 , G05D7/0676 , G08C17/02 , H04B7/2609 , Y10T29/49236 , Y10T29/494 , Y10T29/49412 , Y10T29/49826
摘要： A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

94. 发明申请

US20120209178A1 ADHESIVE AND PERIPHERAL SYSTEMS AND METHODS FOR MEDICAL DEVICES 审中-公开
公开(公告)号：US20120209178A1
公开(公告)日：2012-08-16
申请号：US12617903
申请日：2009-11-13
申请人： Larry B. Gray
发明人： Larry B. Gray
IPC分类号： A61M5/36
CPC分类号： A61M5/5086 , A61B5/0024 , A61B5/1427 , A61B5/6833 , A61B2560/0412 , A61J1/20 , A61M5/1413 , A61M5/142 , A61M5/14212 , A61M5/14216 , A61M5/14224 , A61M5/14244 , A61M5/14248 , A61M5/1452 , A61M5/14586 , A61M5/158 , A61M5/162 , A61M5/168 , A61M5/16804 , A61M5/16809 , A61M5/16813 , A61M5/16831 , A61M5/16886 , A61M5/172 , A61M5/1723 , A61M5/365 , A61M2005/1402 , A61M2005/14208 , A61M2005/14252 , A61M2005/14268 , A61M2005/14506 , A61M2005/1583 , A61M2005/1585 , A61M2005/1586 , A61M2005/16863 , A61M2205/0266 , A61M2205/0294 , A61M2205/04 , A61M2205/16 , A61M2205/18 , A61M2205/3303 , A61M2205/3331 , A61M2205/3337 , A61M2205/3368 , A61M2205/3375 , A61M2205/3379 , A61M2205/3523 , A61M2205/3546 , A61M2205/3569 , A61M2205/3576 , A61M2205/3592 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/8206 , A61M2205/8237 , A61M2206/22 , A61M2207/00 , A61M2209/045 , A61M2230/201 , G01F22/00 , G05B23/02 , G05D7/0647 , G05D7/0676 , G08C17/02 , H04B7/2609 , Y10T29/49236 , Y10T29/494 , Y10T29/49412 , Y10T29/49826
摘要： A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.

95. 发明申请

US20120022494A1 MATRIX INFUSION PUMP AND DISPOSABLE SET 有权
标题翻译： MATRIX输液泵和散装套装
公开(公告)号：US20120022494A1
公开(公告)日：2012-01-26
申请号：US12842856
申请日：2010-07-23
申请人： Gregg Kirkpatrick
发明人： Gregg Kirkpatrick
IPC分类号： A61M5/168 , A61M5/142
CPC分类号： A61M5/16877 , A61M5/1408 , A61M5/14228 , A61M5/16827 , A61M2205/12 , A61M2205/128 , A61M2205/3334 , A61M2206/22
摘要： A matrix infusion cassette for use with an intravenous (IV) pump is disclosed. The matrix infusion cassette includes a body configured to attach to the IV pump, the body having one or more inlet ports, an outlet port, and a plurality of pumping chambers, and a plurality of fluid conduits connecting the inlet ports to at least one pumping chamber, interconnecting the pumping chambers, and connecting at least one pumping chamber to the outlet port.
摘要翻译：公开了一种用于静脉内（IV）泵的矩阵输注盒。矩阵输注盒包括构造成附接到IV泵的主体，主体具有一个或多个入口端口，出口端口和多个抽吸室，以及多个流体导管，其将入口端口连接到至少一个泵送连接泵送室，并将至少一个泵送室连接到出口。

96. 发明授权

US07815604B2 Large volume bolus device and method 有权
标题翻译：大体积推注装置及方法
公开(公告)号：US07815604B2
公开(公告)日：2010-10-19
申请号：US11321197
申请日：2005-12-29
申请人： Roger Dillard Massengale , Kenneth W. Rake , Eric Mabry
发明人： Roger Dillard Massengale , Kenneth W. Rake , Eric Mabry
IPC分类号： A61M37/00 , A61M1/00 , A61M31/00
CPC分类号： A61M5/1424 , A61M5/152 , A61M2005/1405 , A61M2206/22
摘要： A device and method for the infusion of medicinal fluid at a controlled flow rate to a wound site or the blood stream of a patient is disclosed. A pump delivers fluid under pressure from a fluid source through a continuous and substantially constant flow path and through a supplemental bolus dose flow path. A large volume bolus dose reservoir accumulates a large quantity of fluid from the bolus dose flow path and holds the fluid under pressure. A flow regulator controls the fill rate of the large volume bolus reservoir. The large volume supplemental bolus dose is released from the bolus reservoir upon patient activation of a valve. The release rate of the bolus dose is controlled by the decompression of an elastomeric sphere or spring chamber, by the pressure gradient at the valve and/or by optional flow control tubing. In one embodiment, a source of fluid under pressure is pumped at a continuous and substantially constant rate to a wound site or the blood stream of a patient and into a bolus syringe, which is capable of holding a large quantity of fluid under pressure. A plunger on the bolus syringe may be depressed to release a bolus dose of fluid into a chamber accumulator and then to the patient at a controlled release rate.
摘要翻译：公开了一种将受控流速的药液输注到患者的伤口部位或血流的装置和方法。泵在流体源的压力下通过连续且基本上恒定的流动路径并通过补充推注剂量流动路径输送流体。大体积推注剂量储存器从推注剂量流动路径积聚大量流体并将流体保持在压力下。流量调节器控制大容量弹丸储存器的填充率。患者激活瓣膜后，大量补充推注剂量从推注储液器中释放。推注剂量的释放速率由弹性体球体或弹簧室的减压，阀门处的压力梯度和/或可选的流量控制管道控制。在一个实施方案中，将压力下的流体源以连续且基本上恒定的速率泵送到患者的伤口部位或血流，并进入能够在压力下保持大量流体的推注注射器。推注注射器上的柱塞可以被压下以将推注剂量的流体释放到腔室蓄能器中，然后以受控释放速率释放到患者体内。

97. 发明授权

US07640947B2 Microfabricated fluidic circuit elements and applications 失效
标题翻译：微型流体回路元件及应用
公开(公告)号：US07640947B2
公开(公告)日：2010-01-05
申请号：US12144603
申请日：2008-06-23
申请人： David Fernandes , Hou-Pu Chou , Marc A. Unger
发明人： David Fernandes , Hou-Pu Chou , Marc A. Unger
IPC分类号： F15C3/00
CPC分类号： F15C3/00 , A61M2206/22 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L2200/0621 , B01L2200/14 , B01L2300/123 , B01L2400/0487 , B01L2400/0638 , B01L2400/0655 , F15C3/04 , F16K99/0001 , F16K99/0009 , F16K99/0015 , F16K99/0034 , F16K99/0059 , F16K2099/0074 , F16K2099/008 , F16K2099/0082 , F16K2099/0084 , G06F17/509 , G06F2217/16 , H01H2029/008 , Y10T137/206 , Y10T137/2202 , Y10T137/2218 , Y10T137/2224 , Y10T137/7879 , Y10T137/7891 , Y10T137/7892
摘要： Microfabricated fluidic devices of the present invention include switches that can be opened and closed to allow or block the flow of fluid through a channel in response to the pressure level in a gate of the switch. The microfabricated fluidic switches may be coupled together to perform logic functions and Boolean algebra, such as inverters, AND gates, NAND, gates, NOR gates, and OR gates. The logic gates may be coupled together to form flip-flops that latch signals. The present invention also includes microfabricated fluidic pressure multipliers that increase the pressure in a second chamber relative to a first chamber. Microfabricated fluidic devices of the present invention also include high or low pressure sources. A pressure source of the present includes a pump coupled to a reservoir through unidirectional valves. Microfabricated fluidic devices of the present invention may also include devices that perform analog functions such as switching regulator.
摘要翻译：本发明的微型流体装置包括可以打开和关闭的开关，以响应于开关的门中的压力水平来允许或阻止流体通过通道的流动。微制造的流体开关可以耦合在一起以执行逻辑功能和布尔代数，例如反相器，与门，NAND，门，NOR门和或门。逻辑门可以耦合在一起以形成锁存信号的触发器。本发明还包括相对于第一腔室增加第二腔室中的压力的微制造流体压力倍增器。本发明的微型流体装置还包括高压或低压源。本发明的压力源包括通过单向阀联接到储存器的泵。本发明的微型流体装置还可以包括执行诸如开关调节器的模拟功能的装置。

98. 发明申请

US20070244435A1 Fluid delivery system with pump cassette 有权
标题翻译：带泵盒的流体输送系统
公开(公告)号：US20070244435A1
公开(公告)日：2007-10-18
申请号：US11403119
申请日：2006-04-12
申请人： Jeffrey Hicks
发明人： Jeffrey Hicks
IPC分类号： A61M37/00
CPC分类号： A61M5/14236 , A61M5/007 , A61M5/16804 , A61M5/44 , A61M2205/12 , A61M2205/6018 , A61M2206/22
摘要： The fluid delivery system includes a control console adapted to control delivery of fluid to a patient and a pump cassette disposed in a pump cassette socket in the control console and operatively controlled by the control console. The pump cassette includes a pump housing formed by opposing housing members that cooperatively define a pump chamber. A pair of meshed gears is disposed in the pump chamber and separate the pump chamber into a fluid inlet area and a fluid outlet area accessible through respective inlet and outlet ports in the pump housing. The gears are adapted to pressurize fluid for delivery to the patient. Other features of the system include a fluid heater upstream of the pump cassette, air detectors associated with the inlet and outlet ports of the pump cassette, and a sensor to read an encoding device associated with the pump cassette.
摘要翻译：流体输送系统包括控制台，其适于控制向患者输送流体和设置在控制控制台中的泵盒插座中的泵盒，并由控制台操作控制。泵盒包括由壳体构件形成的泵壳体，该壳体构件协同地限定泵室。一对啮合齿轮设置在泵室中，并将泵室分离成流体入口区域和流体出口区域，可通过泵壳体中的相应入口和出口进入。齿轮适于加压流体以递送给患者。该系统的其他特征包括在泵盒上游的流体加热器，与泵盒的入口和出口相关联的空气检测器，以及用于读取与泵盒相关联的编码装置的传感器。

99. 发明申请

US20070219597A1 Adhesive and peripheral systems and methods for medical devices 有权
标题翻译：医疗器械的粘合剂和外围系统和方法
公开(公告)号：US20070219597A1
公开(公告)日：2007-09-20
申请号：US11704897
申请日：2007-02-09
申请人： Dean Kamen , Larry Gray , Russell Beavis
发明人： Dean Kamen , Larry Gray , Russell Beavis
IPC分类号： A61N1/00
CPC分类号： A61M5/5086 , A61B5/0024 , A61B5/1427 , A61B5/6833 , A61B2560/0412 , A61J1/20 , A61M5/1413 , A61M5/142 , A61M5/14212 , A61M5/14216 , A61M5/14224 , A61M5/14244 , A61M5/14248 , A61M5/1452 , A61M5/14586 , A61M5/158 , A61M5/162 , A61M5/168 , A61M5/16804 , A61M5/16809 , A61M5/16813 , A61M5/16831 , A61M5/16886 , A61M5/172 , A61M5/1723 , A61M5/365 , A61M2005/1402 , A61M2005/14208 , A61M2005/14252 , A61M2005/14268 , A61M2005/14506 , A61M2005/1583 , A61M2005/1585 , A61M2005/1586 , A61M2005/16863 , A61M2205/0266 , A61M2205/0294 , A61M2205/04 , A61M2205/16 , A61M2205/18 , A61M2205/3303 , A61M2205/3331 , A61M2205/3337 , A61M2205/3368 , A61M2205/3375 , A61M2205/3379 , A61M2205/3523 , A61M2205/3546 , A61M2205/3569 , A61M2205/3576 , A61M2205/3592 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/8206 , A61M2205/8237 , A61M2206/22 , A61M2207/00 , A61M2209/045 , A61M2230/201 , G01F22/00 , G05B23/02 , G05D7/0647 , G05D7/0676 , G08C17/02 , H04B7/2609 , Y10T29/49236 , Y10T29/494 , Y10T29/49412 , Y10T29/49826
摘要： A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.
摘要翻译：中继器系统可以通过使用中继器和用户接口来控制泵。胶粘贴片系统可用于将泵或其它物体固定在人体上。这种粘合贴片系统可以包括两组粘合剂构件，每个构件在至少一侧上包括粘合剂材料以附接到身体。第一组的构件间隔开以允许第二组的构件在设置在第一组的构件之间的空间中附接到主体，并且第二组的构件间隔开以允许第一组的构件分离从身体没有分离第二组的成员。此外，为个人泵系统提供了填充站和基站。

100. 发明申请

US20060106367A1 Large volume bolus device and method 有权
公开(公告)号：US20060106367A1
公开(公告)日：2006-05-18
申请号：US11321197
申请日：2005-12-29
申请人： Roger Massengale , Kenneth Rake , Eric Mabry
发明人： Roger Massengale , Kenneth Rake , Eric Mabry
IPC分类号： A61K9/22
CPC分类号： A61M5/1424 , A61M5/152 , A61M2005/1405 , A61M2206/22
摘要： A device and method for the infusion of medicinal fluid at a controlled flow rate to a wound site or the blood stream of a patient is disclosed. A pump delivers fluid under pressure from a fluid source through a continuous and substantially constant flow path and through a supplemental bolus dose flow path. A large volume bolus dose reservoir accumulates a large quantity of fluid from the bolus dose flow path and holds the fluid under pressure. A flow regulator controls the fill rate of the large volume bolus reservoir. The large volume supplemental bolus dose is released from the bolus reservoir upon patient activation of a valve. The release rate of the bolus dose is controlled by the decompression of an elastomeric sphere or spring chamber, by the pressure gradient at the valve and/or by optional flow control tubing. In one embodiment, a source of fluid under pressure is pumped at a continuous and substantially constant rate to a wound site or the blood stream of a patient and into a bolus syringe, which is capable of holding a large quantity of fluid under pressure. A plunger on the bolus syringe may be depressed to release a bolus dose of fluid into a chamber accumulator and then to the patient at a controlled release rate.

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