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91. 发明申请

US20180266973A1 PATHOGEN DETECTION 审中-公开
公开(公告)号：US20180266973A1
公开(公告)日：2018-09-20
申请号：US15892765
申请日：2018-02-09
申请人： Covidien LP
发明人： Phillip Shaltis
IPC分类号： G01N27/02 , C12Q1/04 , A61M39/02 , G01N33/483
CPC分类号： G01N27/028 , A61B5/053 , A61B5/412 , A61B5/6801 , A61B5/6852 , A61M5/5086 , A61M39/0247 , A61M2039/0258 , A61M2039/0267 , A61M2039/0276 , A61M2039/0282 , A61M2039/0285 , A61M2205/3317 , C12Q1/04 , G01N33/4833
摘要： In some examples, a pathogen detection sensor includes an electrical circuit changeable from a first impedance state to a second impedance state in response to a change in the presence of pathogens (e.g., in response to pathogen growth). A substrate of a vascular access includes at least a part of the pathogen detection sensor, such as, for example, part of the electrical circuit. In this way, the pathogen detection sensor may be positionable proximate to a vascular access site in order to detect the presence of pathogens at or near a vascular access site of a patient.

92. 发明授权

US10052470B2 Assemblies for identifying a power injectable access port 有权
公开(公告)号：US10052470B2
公开(公告)日：2018-08-21
申请号：US14171364
申请日：2014-02-03
申请人： Bard Peripheral Vascular, Inc.
发明人： Kelly B. Powers , Jim C. Beasley , Guy Rome
IPC分类号： A61M39/02 , A61M39/04 , A61B6/00 , A61M5/00 , A61B6/12 , A61M5/158 , A61M5/162 , A61M5/32 , A61M39/00
CPC分类号： A61M39/0208 , A61B6/12 , A61B6/481 , A61M5/007 , A61M5/158 , A61M5/162 , A61M5/3273 , A61M39/0247 , A61M39/04 , A61M2005/1581 , A61M2005/325 , A61M2039/0009 , A61M2039/0045 , A61M2039/0054 , A61M2039/0063 , A61M2039/0072 , A61M2039/0205 , A61M2039/0238 , A61M2039/0258 , A61M2039/027 , A61M2039/0282 , A61M2039/0288 , A61M2205/32 , A61M2205/6009 , A61M2205/6054 , A61M2205/6081 , Y10T428/139
摘要： An assembly for identifying a power injectable vascular access port, including a vascular access port and an identification feature. The port is structured for power injection and includes a housing and a septum together defining a reservoir. A radiographic feature incorporated into the port is perceivable via x-ray following subcutaneous implantation, the radiographic feature identifying the port as suitable for flowing fluid at a fluid flow rate of at least 1 mL/sec therethrough. A structural feature of the port is perceivable via palpation following subcutaneous implantation, the structural feature identifying the port as suitable for accommodating a pressure within the reservoir of at least 35 psi. The identification feature is separated from the port and confirms that the port is both suitable for flowing fluid at a rate of at least 1 mL/sec therethrough and suitable for accommodating a pressure within the reservoir of at least 35 psi.

93. 发明授权

US10034963B2 Methods and devices for cellular transplantation 有权
公开(公告)号：US10034963B2
公开(公告)日：2018-07-31
申请号：US14993416
申请日：2016-01-12
申请人： Sernova Corporation
发明人： Craig Hasilo , Justin Leushner , Daniel Nicholas Haworth , Simon Shohet , Philip Michael Toleikis , Delfina Maria Mazzuca Siroen
IPC分类号： A61L27/38 , A61F2/02 , A61L27/58 , A61M39/02 , A61L27/54 , A61L27/16 , A61L27/56 , C12N5/071 , A61K35/12
CPC分类号： A61L27/3886 , A61F2/022 , A61K35/12 , A61L27/16 , A61L27/3804 , A61L27/3834 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/64 , A61L2400/18 , A61L2420/00 , A61M39/0247 , A61M2039/0282 , C12N5/0677 , C12N2533/30 , C08L23/12
摘要： Devices and methods for transplanting cells in a host body are described. The cell comprises a porous scaffold that allows ingrowth of vascular and connective tissues, a plug or plug system configured for placement within the porous scaffold, and a seal configured to enclose a proximal opening in the porous scaffold. The device may further comprise a cell delivery device for delivering cells into the porous scaffold. The method of cell transplantation comprises a two step process. The device is incubated in the host body to form a vascularized collagen matrix around a plug positioned within the porous scaffold. The plug is then retracted from the porous scaffold, and cells are delivered into the vascularized space created within the porous scaffold.

94. 发明授权

US10016585B2 Assemblies for identifying a power injectable access port 有权
公开(公告)号：US10016585B2
公开(公告)日：2018-07-10
申请号：US14748917
申请日：2015-06-24
申请人： C. R. Bard, Inc.
发明人： Kelly B. Powers , David M. Cise , Dwight T. Hibdon , John G. Evans
IPC分类号： A61M39/02 , A61M39/04 , A61B6/00 , A61M5/00 , A61B6/12 , A61M5/158 , A61M5/162 , A61M5/32 , A61M39/00
CPC分类号： A61M39/0208 , A61B6/12 , A61B6/481 , A61M5/007 , A61M5/158 , A61M5/162 , A61M5/3273 , A61M39/0247 , A61M39/04 , A61M2005/1581 , A61M2005/325 , A61M2039/0009 , A61M2039/0045 , A61M2039/0054 , A61M2039/0063 , A61M2039/0072 , A61M2039/0205 , A61M2039/0238 , A61M2039/0258 , A61M2039/027 , A61M2039/0282 , A61M2039/0288 , A61M2205/32 , A61M2205/6009 , A61M2205/6054 , A61M2205/6081 , Y10T428/139
摘要： A power-injectable access port suitable for providing subcutaneous access to a patient and suitable for power injection. The access port includes a septum, a housing, and a reservoir defined by the septum and the housing. The septum may include a material that seals passages formed by puncturing the septum with a hollow slender element or another suitable access mechanism, and a radiopaque material forming a selected pattern when an x-ray is taken through the septum for identifying the power-injectable access port as being suitable for power injection. The housing and the septum may be structured for accommodating a pressure developed within the reservoir of at least 35 psi. The power-injectable access port may be designed to accommodate a flow rate of at least 1 milliliter per second of a fluid.

95. 发明申请

US20170056625A1 DEVICES FOR TRANSVASCULAR RETROGRADE ACCESS PLACEMENT 审中-公开
标题翻译：用于血管切除术的设备
公开(公告)号：US20170056625A1
公开(公告)日：2017-03-02
申请号：US15347478
申请日：2016-11-09
申请人： Lakshmikumar PILLAI
发明人： Lakshmikumar PILLAI
IPC分类号： A61M25/09
CPC分类号： A61M25/09041 , A61M25/0068 , A61M25/0133 , A61M25/0136 , A61M25/09 , A61M39/0247 , A61M2025/0681 , A61M2025/09116 , A61M2025/09125 , A61M2025/09175 , A61M2025/09183 , A61M2039/0258 , A61M2039/0273 , A61M2039/0282
摘要： The present invention relates to methods of transvascular retrograde access placement and to devices that facilitate these methods. For purposes of the present invention, transvascular retrograde access placement generally comprises the insertion of a vascular catheter into a central blood vessel through the puncturing of the central blood vessel from the inside of the central blood vessel with a needle or other similarly configured device, or a needle-tipped guidewire of the present invention, and exiting that needle from the patient through the skin rather than the traditional approach of inserting a needle from the outside of the skin surface to the inside of a blood vessel.
摘要翻译：本发明涉及经血管逆行进入放置的方法以及促进这些方法的装置。为了本发明的目的，经血管逆行进入放置通常包括通过用针或其它类似配置的装置从中央血管的内部刺穿中央血管将血管导管插入中央血管，或本发明的针尖导丝，并且通过皮肤从患者身体离开该针，而不是将针从皮肤表面的外部插入血管内部的传统方法。

96. 发明申请

US20160067470A1 PARTIALLY-IMPLANTABLE PORT FOR LONG-TERM CENTRAL VENOUS CATHETER 审中-公开
标题翻译：长期中央通风管的部分可插入口
公开(公告)号：US20160067470A1
公开(公告)日：2016-03-10
申请号：US14823553
申请日：2015-08-11
申请人： Marcos Augusto Silva Pires e Albuquerque
发明人： Marcos Augusto Silva Pires e Albuquerque
IPC分类号： A61M39/02
CPC分类号： A61M39/0247 , A61M2039/0205 , A61M2039/0258 , A61M2039/0264 , A61M2039/0276 , A61M2039/0279 , A61M2039/0282
摘要： A partially implantable port underneath the skin of a patient's body comprising at least one tank element, a medication outlet fixedly connected to said at least one tank element, an upright tubular element having a lower portion fixedly connected to an upper portion of said at least one tank element and having an upper portion provided with a connecting element, a blocking element being provided into said upright tubular element, said upper portion of said at least one tank element remaining outside the skin of a patient after the partially implantable port is implanted.
摘要翻译：包括至少一个储罐元件，固定地连接到所述至少一个储罐元件的药物出口的直立管状元件，其下部固定地连接到所述至少一个储罐元件的上部，并且具有设置有连接元件的上部，在所述直立管状元件中设置阻挡元件，所述至少一个储罐元件的所述上部在植入可植入端口之后保留在患者皮肤外部。

97. 发明申请

US20160051806A1 Ductus side-entry jackets and prosthetic disorder response systems 审中-公开
标题翻译： Ductus侧入夹克和假体障碍反应系统
公开(公告)号：US20160051806A1
公开(公告)日：2016-02-25
申请号：US14121365
申请日：2014-08-25
申请人： David S. Goldsmith
发明人： David S. Goldsmith
IPC分类号： A61M37/00 , A61N1/00 , A61F2/82 , A61N2/00
CPC分类号： A61N1/00 , A61M39/0247 , A61M2039/0276 , A61M2039/0282
摘要： Provided are means for the direct and continuous connection of a catheter to the lumen of any tubular anatomical structure, or ductus, without medically significant leakage. A port implanted at the body surface with piping to a periductal collar allows drug or radionuclide delivery that bypasses the upstream lumen. The port allows injection, infusion, or attachment of an automatic ambulatory pump. A superparamagnetic nanoparticle carrier-bound drug, for example, can be introduced into the lumen to pass downstream until the carrier particles, with or without the drug still bound, are drawn into the lumen wall by a magnetized jacket surrounding the ductus. Such constitutes a method of drug targeting whereby a segment of a vessel or the territory supplied by a branch of that segment can be circumscribed for exposure to the drug. A jacket with side-entry connector positioned in surrounding relation to a lesion requiring treatment can itself be magnetized.
摘要翻译：提供了用于将导管直接和连续地连接到任何管状解剖结构或导管的内腔的装置，而没有医学上显着的泄漏。植入人体表面的管道到管道外环的端口允许绕过上游管腔的药物或放射性核素递送。该端口允许注射，输注或附加自动流动泵。例如，可以将超顺磁性纳米颗粒载体结合的药物引入内腔以通过下游直到具有或不与药物仍然结合的载体颗粒通过围绕导管的磁化护套吸入管腔壁。这样构成药物靶向的方法，由此可以限制由该部分的分支提供的血管的一部分或区域以暴露于药物。具有侧面入口连接器的护套可以被自动地磁化，该夹套定位在与需要治疗的病变的周围关系中。

98. 发明申请

US20150209479A1 METHODS AND DEVICES FOR CELLULAR TRANSPLANTATION 审中-公开
标题翻译：用于细胞移植的方法和装置
公开(公告)号：US20150209479A1
公开(公告)日：2015-07-30
申请号：US14625135
申请日：2015-02-18
申请人： Sernova Corporation
发明人： Craig Hasilo , Justin Leushner , Daniel Nicholas Haworth , Simon Shohet , Philip Michael Toleikis , Delfina Maria Mazzuca Siroen
IPC分类号： A61L27/56 , A61L27/54 , A61L27/16
CPC分类号： A61L27/3886 , A61F2/022 , A61K35/12 , A61L27/16 , A61L27/3804 , A61L27/3834 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/64 , A61L2400/18 , A61L2420/00 , A61M39/0247 , A61M2039/0282 , C12N5/0677 , C12N2533/30 , C08L23/12
摘要： Devices and methods for transplanting cells in a host body are described. The cell comprises a porous scaffold that allows ingrowth of vascular and connective tissues, a plug or plug system configured for placement within the porous scaffold, and a seal configured to enclose a proximal opening in the porous scaffold. The device may further comprise a cell delivery device for delivering cells into the porous scaffold. The method of cell transplantation comprises a two step process. The device is incubated in the host body to form a vascularized collagen matrix around a plug positioned within the porous scaffold. The plug is then retracted from the porous scaffold, and cells are delivered into the vascularized space created within the porous scaffold.
摘要翻译：描述了用于在宿主体中移植细胞的装置和方法。该细胞包括允许血管和结缔组织向内生长的多孔支架，构造成放置在多孔支架内的塞子或塞子系统以及被构造成封闭多孔支架中的近端开口的密封件。该装置还可以包括用于将细胞递送到多孔支架中的细胞递送装置。细胞移植的方法包括两步法。将该装置在宿主体中孵育以在位于多孔支架内的插塞周围形成血管化的胶原基质。然后将塞子从多孔支架中缩回，并将细胞递送到在多孔支架内产生的血管化空间。

99. 发明申请

US20150190622A1 MEDICAL HUB AND METHOD OF USING SAME 审中-公开
标题翻译：医用集束及其使用方法
公开(公告)号：US20150190622A1
公开(公告)日：2015-07-09
申请号：US14627749
申请日：2015-02-20
申请人： Mark A. Saab
发明人： Mark A. Saab
IPC分类号： A61M39/02 , A61M25/00
CPC分类号： A61M39/0208 , A61M1/285 , A61M25/0097 , A61M39/0247 , A61M2039/0258 , A61M2039/0261 , A61M2039/0273 , A61M2039/0282 , A61M2039/0285
摘要： Methods and apparatus are disclosed for making and using adjustable epidermal tissue ingrowth cuff and catheter assemblies for transcutaneous placement to provide periodic or continuous external access for medical purposes to an interior body region of a patent who requires such medical treatment over an extended period of time.
摘要翻译：公开了用于制造和使用可调节的表皮组织向内生长袖带和导管组件用于经皮放置的方法和装置，以向医疗目的提供周期性或连续的外部接近用于在长时间内需要这种治疗的专利的内部身体区域。

100. 发明授权

US09011899B2 Methods and devices for cellular transplantation 有权
标题翻译：细胞移植的方法和装置
公开(公告)号：US09011899B2
公开(公告)日：2015-04-21
申请号：US13393038
申请日：2010-08-27
申请人： Craig Hasilo , Justin Leushner , Daniel Nicholas Haworth , Simon Shohet , Philip Michael Toleikis , Delfina Maria Mazzuca Siroen
发明人： Craig Hasilo , Justin Leushner , Daniel Nicholas Haworth , Simon Shohet , Philip Michael Toleikis , Delfina Maria Mazzuca Siroen
IPC分类号： A61F2/02 , A61L27/38 , A61L27/16 , A61L27/56 , C12N5/071 , A61K35/12
CPC分类号： A61L27/3886 , A61F2/022 , A61K35/12 , A61L27/16 , A61L27/3804 , A61L27/3834 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/64 , A61L2400/18 , A61L2420/00 , A61M39/0247 , A61M2039/0282 , C12N5/0677 , C12N2533/30 , C08L23/12
摘要： Devices and methods for transplanting cells in a host body are described. The cell comprises a porous scaffold that allows ingrowth of vascular and connective tissues, a plug or plug system configured for placement within the porous scaffold, and a seal configured to enclose a proximal opening in the porous scaffold. The device may further comprise a cell delivery device for delivering cells into the porous scaffold. The method of cell transplantation comprises a two step process. The device is incubated in the host body to form a vascularized collagen matrix around a plug positioned within the porous scaffold. The plug is then retracted from the porous scaffold, and cells are delivered into the vascularized space created within the porous scaffold.
摘要翻译：描述了用于在宿主体中移植细胞的装置和方法。该细胞包括允许血管和结缔组织向内生长的多孔支架，构造成放置在多孔支架内的塞或塞系统，以及密封件，其构造成封闭多孔支架中的近端开口。该装置还可以包括用于将细胞递送到多孔支架中的细胞递送装置。细胞移植的方法包括两步法。将该装置在宿主体中孵育以在位于多孔支架内的插塞周围形成血管化的胶原基质。然后将塞子从多孔支架中缩回，并将细胞递送到在多孔支架内产生的血管化空间。

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