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91. 发明申请

US20110040241A1 BLOOD ACCESS ASSEMBLY FOR ARTIFICIAL LUNG AND RIGHT VENTRICULAR ASSIST DEVICE 审中-公开
标题翻译：用于人造肺和右心室辅助装置的血液通入装置
公开(公告)号：US20110040241A1
公开(公告)日：2011-02-17
申请号：US12539110
申请日：2009-08-11
申请人： Dongfang Wang , Joseph B. Zwischenberger
发明人： Dongfang Wang , Joseph B. Zwischenberger
IPC分类号： A61M5/00 , A61M1/00
CPC分类号： A61M1/3653 , A61M1/3655 , A61M1/3656 , A61M1/3659
摘要： A system for providing access to at least one heart chamber for delivering and/or removing a fluid includes a selectively occludable conduit defining a lumen for providing access to an interior of at least one heart chamber from an exterior of a chest wall of the patient, and a dual lumen cannula adapted for passing through an interior lumen of the conduit. The selectively occludable conduit includes at least one balloon closure for substantially sealing an end of the conduit in fluid communication with the chamber of the heart. The dual lumen cannula includes a first, drainage lumen having at least one aperture for removing a fluid from the interior of the heart chamber, and a second, delivery lumen for delivering a fluid into the interior of the heart chamber. The delivery lumen may include an extendable infusion sleeve for delivering a fluid into an interior of the heart.
摘要翻译：用于提供进入至少一个心室的输送和/或去除流体的系统包括限定内腔的选择性可闭塞导管，用于从患者胸壁的外部提供进入至少一个心室的内部，以及适于穿过导管的内腔的双腔插管。选择性可闭塞管道包括至少一个气囊盖，用于基本上密封导管的与心脏腔室流体连通的端部。双腔套管包括具有至少一个用于从心脏腔室内部移除流体的孔的第一排液腔和用于将流体输送到心室的内部的第二输送腔。输送腔可以包括用于将流体输送到心脏内部的可伸展输液套筒。

92. 发明申请

US20100286705A1 VASCULAR ACCESS TO EXTRA-VASCULAR SPACE 审中-公开
标题翻译：血管获取外部空间
公开(公告)号：US20100286705A1
公开(公告)日：2010-11-11
申请号：US12811892
申请日：2009-01-30
申请人： Thomas A. Vassiliades, JR.
发明人： Thomas A. Vassiliades, JR.
IPC分类号： A61B17/00
CPC分类号： A61M25/00 , A61B17/320016 , A61B17/3209 , A61B2017/1107 , A61B2017/1139 , A61F2/06 , A61F2/064 , A61F2/2493 , A61M1/3655
摘要： Provided are methods for accessing tissue in the vicinity of a blood vessel. Also provided are devices for use in a lumen of a patient's organ and methods for shunting interior volumes of organs.
摘要翻译：提供了用于访问血管附近的组织的方法。还提供了用于患者器官的内腔中的装置和用于分流内部体积的器官的方法。

93. 发明申请

US20100268265A1 RETRIEVAL APPARATUS AND METHODS FOR USE 有权
标题翻译：检索装置和使用方法
公开(公告)号：US20100268265A1
公开(公告)日：2010-10-21
申请号：US12746920
申请日：2008-12-10
申请人： Jeffrey A. Krolik , Gwendolyn Watanabe , James H. Dreher
发明人： Jeffrey A. Krolik , Gwendolyn Watanabe , James H. Dreher
IPC分类号： A61F2/01
CPC分类号： A61B17/221 , A61B2017/00862 , A61B2017/22035 , A61B2017/22038 , A61B2017/2212 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0069 , A61M1/3655
摘要： An apparatus for capturing material within a body lumen includes a shaft carrying an expandable basket device on a distal end thereof. The basket device includes a distal basket carried and a proximal basket carried on the shaft such that the proximal basket is proximal to and spaced apart from the distal basket. Each basket includes an open end communicating with an interior of the respective basket and oriented towards one another. In one embodiment, a tubular middle portion extends between the baskets. In another embodiment, the distal basket includes an actuator coupled to the distal basket open end such that movement of the baskets towards one another causes the actuator to direct the distal basket open end inwardly to allow the open end to be received within the proximal basket to facilitate removal of the apparatus after capturing material within the baskets.
摘要翻译：用于在体腔内捕获材料的装置包括在其远端承载可膨胀篮装置的轴。篮子装置包括承载的远侧篮子和承载在轴上的近侧篮，使得近侧篮子靠近并与远侧篮子间隔开。每个篮子包括与相应篮子的内部相通并且朝向彼此定向的开放端。在一个实施例中，管状中间部分在篮子之间延伸。在另一个实施例中，远侧筐包括联接到远侧筐开口端的致动器，使得篮子朝向彼此的移动导致致动器将远侧筐开放端向内引导，以允许开放端被容纳在近侧筐内便于在筐内捕获材料之后移除设备。

94. 发明授权

US07811264B2 Dialysis valve and method 有权
标题翻译：透析阀及方法
公开(公告)号：US07811264B2
公开(公告)日：2010-10-12
申请号：US12431101
申请日：2009-04-28
申请人： Timothy J. Claude , Edward A. Barlow , David W. Hunter , Michael S. Rosenberg
发明人： Timothy J. Claude , Edward A. Barlow , David W. Hunter , Michael S. Rosenberg
IPC分类号： A61M5/00
CPC分类号： A61M1/3655 , A61M39/22 , A61M39/228 , A61M2205/0266
摘要： A dialysis valve includes a tube attached between an artery and a vein which, when elongated, simultaneously narrows in diameter at least one location. The narrowed portion of the tube decreases the volume and velocity between the arterial and venous side of the patient to prevent damage or intimal hyperplasia on the venous side between dialysis treatments. When the valve is opened for dialysis, an unrestricted blood flow exists between the arterial and venous side, permitting a controlled, open blood flow during dialysis.
摘要翻译：透析阀包括附接在动脉和静脉之间的管，其在细长时同时在至少一个位置上变窄。管的狭窄部分减少患者的动脉和静脉侧之间的体积和速度，以防止透析治疗之间的静脉侧的损伤或内膜增生。当阀门打开以进行透析时，在动脉和静脉侧之间存在无限制的血流，允许透析期间受控的开放的血流。

95. 发明申请

US20100234789A1 SELF ADJUSTING VENOUS EQUALIZING GRAFT 有权
标题翻译：自调整均衡平衡
公开(公告)号：US20100234789A1
公开(公告)日：2010-09-16
申请号：US12723032
申请日：2010-03-12
申请人： Stanley Batiste , Steven Achstein
发明人： Stanley Batiste , Steven Achstein
IPC分类号： A61M1/00
CPC分类号： A61M1/3653 , A61M1/3655 , A61M1/3659 , A61M1/3661
摘要： A self adjusting venous equalizing graft (SAVE graft) which provides a self regulating stenosis is provided herein. The SAVE graft responds to increases or decreases in blood pressure which allows a higher pressure at the graft's arterial end and a lower pressure at the graft's venous end. This is ideal in that it mimics the natural pressure of a patient's circulatory system. A dialysis machine may draw blood at the arterial end, dialyze the blood, and return the blood to the patient at the graft's venous end. The lower pressure at the venous end prevents damage to the patient's vein. The SAVE graft may comprise a deformable stenosis control diaphragm or a venous controlled pressure nozzle which may expand or contract in response to blood pressure to self regulate the stenosis provided by the SAVE graft.
摘要翻译：本文提供了一种提供自我调节狭窄的自调节静脉平衡移植物（SAVE移植物）。 SAVE移植物对血压的升高或降低作出反应，这允许移植物动脉末端的压力更高，移植物静脉末端的压力较低。这是理想的，因为它模仿了患者循环系统的自然压力。透析机可以在动脉端吸血，透血，并在移植静脉端将血液返回给患者。静脉端的较低压力可防止患者静脉损伤。 SAVE移植物可以包括可变形狭窄控制隔膜或静脉控制压力喷嘴，其可以响应于血压而膨胀或收缩以自我调节由SAVE移植物提供的狭窄。

96. 再颁专利

USRE41448E1 Squitieri hemodialysis and vascular access systems 有权
标题翻译： Squitieri血液透析和血管通路系统
公开(公告)号：USRE41448E1
公开(公告)日：2010-07-20
申请号：US10219998
申请日：2002-08-15
申请人： Rafael P. Squitieri
发明人： Rafael P. Squitieri
IPC分类号： A61M37/00
CPC分类号： A61M1/3653 , A61M1/3655 , A61M39/0208 , A61M2005/1581 , A61M2039/0211 , A61M2039/0258
摘要： A hemodialysis and vascular access system comprises a subcutaneous composite PTFE silastic arteriovenous fistula having an indwelling silastic venous end which is inserted percutaneously into a vein and a PTFE arterial end which is anastomosed to an artery. Access to a blood stream within the system is gained by direct puncture of needle(s) into a needle receiving site having a tubular passage within a metal or plastic frame and a silicone upper surface through which needle(s) are inserted. In an alternate embodiment of the invention, percutaneous access to a blood stream may be gained by placing needles directly into the system (i.e. into the PTFE arterial end). The invention also proposes an additional embodiment having an arterialized indwelling venous catheter where blood flows from an artery through a tube and a port into an arterial reservoir and is returned to a vein via a port and a venous outlet tube distinct and distant from the area where the blood from the artery enters the arterial reservoir. The site where blood is returned to the vein is not directly fixed to the venous wall but is free floating within the vein. This system provides a hemodialysis and venous access graft which has superior longevity and performance, is easier to implant and is much more user friendly.
摘要翻译：血液透析和血管通路系统包括皮下复合PTFE硅橡胶动静脉瘘，其具有经皮插入静脉的留置硅橡胶静脉端和与动脉吻合的PTFE动脉末端。通过将针直接穿刺到金属或塑料框架内具有管状通道的针接收位置和插入针的硅树脂上表面来获得系统内的血流。在本发明的替代实施例中，可以通过将针直接放入系统（即进入PTFE动脉端）来获得对血流的经皮进入。本发明还提出了一种另外的实施例，其具有动脉留置静脉导管，其中血液从动脉通过管和端口流入动脉储存器，并经由口和静脉出口管返回到静脉，所述口和静脉出口管不同于动脉血液进入动脉血管。血液返回静脉的部位不直接固定在静脉壁上，而是静脉内自由浮动。该系统提供血液透析和静脉进入移植物，其具有优越的寿命和性能，更容易植入并且更加用户友好。

97. 发明申请

US20100105990A1 METHOD OF MONITORING HYPERTENSIVE HAEMODIALYSIS PATIENTS 有权
标题翻译：监测高血压病人的方法
公开(公告)号：US20100105990A1
公开(公告)日：2010-04-29
申请号：US12523460
申请日：2008-01-16
申请人： Bernard Bene
发明人： Bernard Bene
IPC分类号： A61B5/00
CPC分类号： A61M1/3656 , A61M1/3653 , A61M1/3655 , A61M1/3658 , G06F19/00 , G06F19/3481 , G16H50/30
摘要： The invention relates to a calculation and control system for determining whether a patient intended to follow several sessions of hemodialysis treatment falls or not within one group among several groups of hypertension-affected patients, the system comprising: a) means for determining the value of at least one parameter representing the mass interdialytic evolution of the patient, for at least two sessions, b) means for determining the value of at least one parameter representing the plasmatic conductivity of the patient for at least two sessions, c) means for determining the value of a parameter representing the ionic mass transfer of the treatment for at least two sessions, d) programmed means for determining whether the patient falls or not within a group of hypertension-affected patients as a function of the interdialytic mass evolution of the patient, and/or of the plasmatic conductivity and/or of the ionic mass transfer.
摘要翻译：本发明涉及一种计算和控制系统，用于确定是否要在几组血液透析治疗之间进行多次血液透析治疗的患者在几组受高血压影响的患者中落在一组内，该系统包括：a）用于确定在用于至少两个会话的至少一个参数，表示患者的质量间盘间变化; b）用于确定表示至少两个会话的患者的血浆电导率的至少一个参数的值的装置，c）用于确定所述值的装置表示治疗至少两次的离子质量转移的参数，d）用于确定患者是否在一组受高血压影响的患者内下降的程序化手段，作为患者的透析间质量演变的函数，以及 /或血浆导电性和/或离子质量转移。

98. 发明申请

US20090326431A1 TUBULAR VASCULAR TRANSPLANT 失效
标题翻译：管状血管移植
公开(公告)号：US20090326431A1
公开(公告)日：2009-12-31
申请号：US12309798
申请日：2007-07-20
申请人： Michael Heise , Christoph Heidenahain
发明人： Michael Heise , Christoph Heidenahain
IPC分类号： A61M1/00
CPC分类号： A61F2/06 , A61F2/064 , A61F2002/068 , A61M1/3655
摘要： A tubular vascular transplant (1, 1′, 1″, 1′″) serves for connecting vessels in the human body. The transplant, in particular made of expanded polytetrafluoroethylene (ePTFE), can preferably be used for an arteriovenous shunt for carrying out a dialysis. The transplant is connected by its first, proximal end to a vessel, for example an artery (2), and by its distal end to another location of the same vessel or to a different vessel, for example a vein (3). The lumen of the transplant (1, 1′, 1″, and 1′″) widens in a steadily conical manner in the region of its distal end and forms a diffuser (8) there. The cone angle (a) of the wall of the diffuser (8) with respect to the central flow direction of the blood in the transplant (1′, 1″, 1′″) is preferably 6° to 7°. In the region of the diffuser (8), preferably at least one, preferably planar, dividing wall (11, 11′, 11a, and 11b) is provided, running in the central flow direction of the blood. This makes it possible to prevent the formation of an intimal hyperplasia and a pseudointima.
摘要翻译：管状血管移植物（1,1'，1“，1”）用于连接人体内的血管。特别是由膨胀聚四氟乙烯（ePTFE）制成的移植物可优选用于进行透析的动静脉分流。移植物通过其第一近端连接到血管，例如动脉（2），并且通过其远端连接到同一血管的另一位置，或连接到不同的血管，例如静脉（3）。移植物的管腔（1,1'，1“和1”“）在其远端的区域中以稳定的锥形方式变宽，并在其上形成扩散器（8）。扩散器（8）的壁相对于移植体（1'，1“，1”“）中的血液的中心流动方向的锥角（a）优选为6°至7°。在扩散器（8）的区域中，优选地设置有沿着血液的中心流动方向延伸的至少一个优选的平面的分隔壁（11,11'，11a和11b）。这使得可以防止内膜增生和假节点的形成。

99. 发明申请

US20090270882A1 NEEDLE COVER WITH SITE PREPARATION TIP 有权
标题翻译：针座与现场准备提示
公开(公告)号：US20090270882A1
公开(公告)日：2009-10-29
申请号：US12307099
申请日：2007-07-02
申请人： Dennis O'Neill
发明人： Dennis O'Neill
IPC分类号： A61B17/50 , A61M5/00
CPC分类号： A61M5/3202 , A61M1/3655
摘要： A needle cover is disclosed which includes a site preparation tip at a distal end of a needle cover body. The tip may be configured with rounded and/or beveled edges in order to facilitate material removal from a cannulation site. The proximal end of the needle cover body may include features to facilitate handling, removal of the needle, and operation of the needle cover in removing material, such as a scab, from a cannulation site.
摘要翻译：公开了一种针盖，其包括在针盖主体的远端处的位置准备尖端。尖端可以配置有圆形和/或斜面边缘，以便于从插管部位移除材料。针盖主体的近端可以包括便于处理，去除针的特征，以及针罩从操作部位移除诸如痂的材料的操作。

100. 发明授权

US07591778B2 Implantable heart assist system and method of applying same 失效
公开(公告)号：US07591778B2
公开(公告)日：2009-09-22
申请号：US11417889
申请日：2006-05-03
申请人： Steven F. Bolling , Anthony Viole , Shawn O'Leary
发明人： Steven F. Bolling , Anthony Viole , Shawn O'Leary
IPC分类号： A61M1/10
CPC分类号： A61M1/101 , A61M1/10 , A61M1/1005 , A61M1/1008 , A61M1/1034 , A61M1/107 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M1/125 , A61M1/3621 , A61M1/3653 , A61M1/3655 , A61M1/3659 , A61M25/0026 , A61M25/003 , A61M25/007 , A61M2230/04
摘要： An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured to couple to a non-primary blood vessel and a second end that is fluidly coupled to a pump to conduct blood between the pump and the non-primary blood vessel. An outflow conduit is also provided that has a first end sized and configured to be positioned within the same or different blood vessel, whether primary or non-primary, through the vascular graft. The outflow conduit is fluidly coupled to the pump to conduct blood between the pump and the patient. The vascular graft may be connected to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure.

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