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91. 发明申请

US20030078753A1 Optimization of ablation correction of an optical system and associated methods 有权
标题翻译：优化光学系统的消融矫正及相关方法
公开(公告)号：US20030078753A1
公开(公告)日：2003-04-24
申请号：US10238919
申请日：2002-09-10
发明人： John Alfred Campin , George H. Pettit
IPC分类号： G06F019/00
CPC分类号： A61B3/1015 , A61B5/103 , A61F9/00806 , A61F2009/00846 , A61F2009/00857 , A61F2009/00872 , A61F2009/0088
摘要： A system and method for converting measured wavefront data into an ablation profile for correcting visual defects includes providing measured wavefront data on an aberrated eye by a method such as known in the art. The measured wavefront data are correlated with accumulated data on previously treated eyes. Next an adjustment is applied to the measured wavefront data based upon the correlating step. This adjustment is used to form adjusted wavefront data for input to a wavefront data correction algorithm to calculate an ablation profile therefrom. The wavefront data correction algorithm may be modeled as, for example, Zernike polynomials with adjusted coefficients.
摘要翻译：用于将测量的波前数据转换成用于校正视觉缺陷的消融轮廓的系统和方法包括通过本领域已知的方法在像差眼上提供测量的波前数据。测量的波前数据与先前治疗的眼睛的累积数据相关。接下来，基于相关步骤对所测量的波前数据进行调整。该调整用于形成用于输入到波前数据校正算法的经调整的波前数据，以从其计算消融轮廓。波前数据校正算法可以被建模为例如具有调整系数的泽尔尼克多项式。

92. 发明申请

US20030073984A1 Corneal-ablation-data determining apparatus and a corneal surgery apparatus 审中-公开
标题翻译：角膜消融数据确定装置和角膜手术装置
公开(公告)号：US20030073984A1
公开(公告)日：2003-04-17
申请号：US10268992
申请日：2002-10-11
申请人： NIDEK CO., LTD.
发明人： Naoyuki Maeda
IPC分类号： A61F009/007
CPC分类号： A61F9/008 , A61B34/10 , A61F9/00806 , A61F9/00817 , A61F2009/00846 , A61F2009/00855 , A61F2009/00872 , A61F2009/0088
摘要： A corneal-ablation-data determining apparatus and a corneal surgery apparatus capable of performing corneal ablation surgery efficiently while improving an aberration of a patient's eye. The corneal-ablation-data determining apparatus for obtaining ablation data for corneal ablation surgery to correct a refractive error by ablating a cornea, the apparatus comprising an input device for inputting measurement data of a patient's eye and size data of an ablation zone and a calculation device for calculating ablation data including aberration improvement data for the patient's eye based on the inputted measurement data and size data, wherein the calculation device divides the ablation zone into a central zone and a peripheral zone outside the central zone, then calculates ablation data for a component not being a non-spherical component in the central zone, and calculates ablation data for a non-spherical component in at least part of the peripheral zone, including the aberration improvement data.
摘要翻译：角膜消融数据确定装置和能够有效地进行角膜消融手术的角膜手术装置，同时改善患者眼睛的像差。角膜消融数据确定装置，用于获得用于角膜切除手术的消融数据，以通过消融角膜来校正屈光不正，该装置包括用于输入患者眼睛的测量数据和消融区域的尺寸数据的输入装置和计算用于根据输入的测量数据和尺寸数据计算包括患者眼睛的像差改善数据的消融数据的装置，其中所述计算装置将所述消融区域划分为中心区域和所述中心区域外部的周边区域，然后计算用于组件不是中心区域中的非球面分量，并且在周边区域的至少一部分中计算非球面分量的消融数据，包括像差改进数据。

93. 发明申请

US20030040738A1 Controllable liquid crystal matrix mask particularly suited for performing ophthamological surgery, a laser system with said mask and a method of using the same 失效
公开(公告)号：US20030040738A1
公开(公告)日：2003-02-27
申请号：US10207073
申请日：2002-07-30
发明人： Luis Antonio Ruiz , Eduardo Matallana
IPC分类号： A61B018/20
CPC分类号： G03F7/70291 , A61F9/00808 , A61F9/00817 , A61F2009/00846 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882
摘要： A system and method particularly suited for controlled ablation of the cornea, using ultraviolet laser radiation, with the cornea sculpturing action resulting from a computer driven digital programmed distribution of excimer flux density across a controllable liquid crystal matrix mask to achieve a desired volume and shape of ablation for the correction of the curvature of the cornea. The optical mask, in one embodiment, is based on an arrayable matrix of individual optical pixel cells with two optical states between fully transparent to fully opaque or mirror like to the UV light. The system provides a highly versatile system for correcting known corneal defects in both regular and irregular corneas by simply executing computer customized patterns in very short time and with great precision and detail.

94. 发明申请

US20030007125A1 Ophthalmic imaging instrument having an adaptive optical subsystem that measures phase aberrations in reflections derived from light produced by an imaging light source and that compensates for such phase aberrations when capturing images of reflections derived from light produced by the same imaging light source 失效
标题翻译：具有自适应光学子系统的眼科成像仪器，其测量由成像光源产生的光导出的反射中的相位差，并且当捕获由相同成像光源产生的光产生的反射的图像时，补偿这种相位像差
公开(公告)号：US20030007125A1
公开(公告)日：2003-01-09
申请号：US09874403
申请日：2001-06-05
申请人： Adaptive Optics Associates, Inc.
发明人： Bruce M. Levine
IPC分类号： A61B003/10
CPC分类号： A61F9/008 , A61B3/103 , A61F2009/00846 , A61F2009/00848 , A61F2009/00855 , A61F2009/00863 , A61F2009/00872 , A61F2009/00882
摘要： An improved ophthalmic imaging instrument including a wavefront sensor-based adaptive optical subsystem that measures phase aberrations in reflections derived from light produced by an imaging light source and compensates for such phase aberrations when capturing images of reflections derived from light produced by the same imaging light source. The high-resolution image data captured by the improved ophthalmic imaging instrument can be used to assist in detection and diagnosis (such as color imaging, fluorescein angiography, indocyanine green angiography) of abnormalities and disease in the human eye and treatment (including pre-surgery preparation and computer-assisted eye surgery such as laser refractive surgery) of abnormalities and disease in the human eye.
摘要翻译：一种改进的眼科成像仪器，包括基于波前传感器的自适应光学子系统，其测量由成像光源产生的光导出的反射中的相位差，并且当捕获由相同成像光源产生的光产生的反射的图像时，补偿这种相位像差。由改进的眼科成像仪捕获的高分辨率图像数据可用于辅助人眼异常和疾病的检测和诊断（例如彩色成像，荧光素血管造影，吲哚青绿血管造影）和治疗（包括手术前准备和计算机辅助眼科手术如激光屈光手术）在人眼中的异常和疾病。

95. 发明授权

US06494878B1 System and method for accurate optical treatment of an eye's fundus 失效
标题翻译：准确光学治疗眼底的系统和方法
公开(公告)号：US06494878B1
公开(公告)日：2002-12-17
申请号：US09569438
申请日：2000-05-12
申请人： Dirk Pawlowski , Wolfgang Neuberger
发明人： Dirk Pawlowski , Wolfgang Neuberger
IPC分类号： A61B1818
CPC分类号： A61F9/008 , A61B3/135 , A61F9/009 , A61F2009/00846 , A61F2009/00863 , A61K41/0042
摘要： A system and method is provided to accurately treat sites on an eye's retina employing computer based image generation, processing and central control means in conjunction with diode laser sources and optical fibers. The system and method accurately determine geometry of a treatment zone of a specific eye's fundus and adjust a treatment beam to irradiate the treatment zone with minimal coverage of adjacent well tissue. The treatment zone or zone is accurately determined with digital processing of angiographic data and slit lamp image data. This information is integrated with information on the treatment beam characteristics to better match treatment beam coverage with minimal overlap with healthy areas of the fundus. Additionally preferred embodiments also have the ability to automatically track eye movement and switch the beam source depending on eye movement, adjusting the beam spot area in real time.
摘要翻译：提供了一种使用基于计算机的图像生成，处理和与二极管激光源和光纤结合的中央控制装置来精确地治疗眼睛视网膜上的部位的系统和方法。该系统和方法准确地确定特定眼底的治疗区的几何形状，并调整治疗束以相邻的井组织的最小覆盖面照射治疗区。通过血管造影数据和裂隙灯图像数据的数字处理准确地确定治疗区域或区域。该信息与治疗波束特征的信息相结合，以更好地匹配治疗波束覆盖，同时与眼底健康区域的重叠最小。另外，优选实施例还具有根据眼睛移动自动跟踪眼睛移动和切换束源的能力，实时调整束斑区域。

96. 发明申请

US20020165526A1 Corneal surgery apparatus 失效
标题翻译：角膜手术器械
公开(公告)号：US20020165526A1
公开(公告)日：2002-11-07
申请号：US10173822
申请日：2002-06-19
申请人： NIDEK CO., LTD
发明人： Toshifumi Sumiya , Mikio Arashima , Hidenori Kanda
IPC分类号： A61F009/007 , A61B018/20
CPC分类号： A61F9/008 , A61B2017/00694 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： An ophthalmic surgery apparatus comprising a system for observing an anterior portion of an eye, and an optical system for irradiating a laser beam for treatment to the eye, the apparatus is a corneal surgery apparatus irradiating the laser beam to a cornea and ablating a surface thereof, the apparatus comprising a moving device for moving the optical system relatively against the eye, an illuminating device for illuminating a large area of the anterior portion of the eye, a photoelectric transducing device having a two-dimensional light sensing plane, for sensing distribution of light volume of the anterior portion of the eye, a pupil position sensing device for sensing the position of a pupil, a control device for controlling the moving device based on sensed results, a tracking signal generating device for generating a signal to track movement of the eye, whereby the moving device is controlled by the control device so as to track movement of the eye by inputting a signal generated by the tracking signal generating device, and a device for prohibiting irradiation of the laser beam in the case that the position of the pupil misses the predetermined limits.
摘要翻译：一种眼科手术装置，包括用于观察眼睛前部的系统和用于将激光束照射到眼睛的光学系统，该装置是将激光束照射到角膜并烧蚀其表面的角膜手术装置该装置包括用于相对于眼睛移动光学系统的移动装置，用于照射眼睛前部的大部分区域的照明装置，具有二维光感测平面的光电转换装置，用于感测用于感测瞳孔位置的光瞳位置检测装置，用于基于感测结果控制移动装置的控制装置;跟踪信号产生装置，用于产生跟踪移动装置的移动的跟踪信号产生装置，眼睛，由此移动装置由控制装置控制，以便通过输入产生的信号跟踪眼睛的移动通过跟踪信号发生装置，以及用于在瞳孔位置错过预定极限的情况下禁止激光束照射的装置。

97. 发明申请

US20020151877A1 MEDICAL LASER GUIDANCE APPARATUS 审中-公开
标题翻译：医用激光指导装置
公开(公告)号：US20020151877A1
公开(公告)日：2002-10-17
申请号：US09214286
申请日：1999-10-01
发明人： WILLIAM MASON
IPC分类号： A61B018/20
CPC分类号： A61F9/008 , A61B2017/00694 , A61F2009/00846 , A61F2009/00863
摘要： An apparatus for applying laser light to the retina of the eye comprises a retina image obtaining means for obtaining the image of a retina. A retina image display displays the required retina image, and reference data receiving means receives, from an operator, data relating to a treatment to be performed. Template generating means generates a reference template on the retina image, and target position receiving means receives data related to at least one target point to which light is to be applied based upon the received reference data. Current retina position detecting means acquires a current retina image, and laser light application means directs and applies laser light to a retina.
摘要翻译：将激光施加到眼睛的视网膜的装置包括用于获得视网膜的图像的视网膜图像获取装置。视网膜图像显示器显示所需的视网膜图像，并且参考数据接收装置从操作者接收与要执行的治疗有关的数据。模板产生装置在视网膜图像上生成参考模板，目标位置接收装置根据接收到的参考数据接收与要施加光的至少一个目标点相关的数据。当前的视网膜位置检测装置获取当前的视网膜图像，并且激光施加装置将激光引导并施加到视网膜。

98. 发明申请

US20020099363A1 Radiation treatment system and method of using same 审中-公开
标题翻译：辐射治疗系统及其使用方法
公开(公告)号：US20020099363A1
公开(公告)日：2002-07-25
申请号：US09770094
申请日：2001-01-23
发明人： Benjamin W. Woodward , Satish V. Herekar , Mark S. Milner
IPC分类号： A61F007/12 , A61B018/18
CPC分类号： A61F9/008 , A61B2090/064 , A61F9/0079 , A61F2009/00846 , A61F2009/00853 , A61F2009/00865 , A61F2009/00872 , A61F2009/00895
摘要： The present invention provides a system and associated method for advantageously treating bodily tissue containing collagen, such as ophthalmic tissue. The treatment includes providing a pattern of heating to which the tissue is to be exposed and the exposure of that tissue to shrink collagen therein. In ophthalmic applications, the pattern includes at least one region that corresponds to an ocular region of from about 4 mm to about 20 mm radially from the optical axis. The shrinkage of collagen within this ocular region improves accommodation for near vision. The present invention thus provides an effective treatment for the ocular condition of presbyopia.
摘要翻译：本发明提供了一种用于有利地处理含有胶原蛋白的身体组织的系统和相关方法，例如眼科组织。该治疗包括提供组织要被暴露的加热模式和该组织的暴露以收缩胶原蛋白。在眼科应用中，图案包括至少一个对应于从光轴径向约4mm至约20mm的眼部区域的区域。胶原蛋白在该眼部区域的收缩增加了近视力的适应性。因此，本发明提供了对老花眼症状的有效治疗。

99. 发明申请

US20020097378A1 Pupil measurement apparatus, refraction correction apparatus, and pupil measurement method 失效
$Pupil measurement apparatus, refraction correction apparatus, and pupil measurement method$
标题翻译：瞳孔测量装置，折射校正装置和瞳孔测量方法
公开(公告)号：US20020097378A1
公开(公告)日：2002-07-25
申请号：US10053916
申请日：2002-01-24
申请人： EXPLORER INC.
发明人： Seiji Saito , Shuichiro Eguchi , Yasuko Ise
IPC分类号： A61B003/14
CPC分类号： A61F9/008 , A61B3/107 , A61F2009/00846
摘要： A video imaging device obtains the eyeball image of a cornea using light emitted from an imaging light source to the cornea. On the basis of the obtained eyeball image, a video processing device calculates the X- and Y-axis shift amounts and torsion angle of the cornea with respect to the reference position and causes a coordinate indicating device to indicate the calculated X- and Y-axis shift amounts and torsion angle. With this arrangement, the position and torsion angle of the cornea of the patient can be accurately detected and measured without forming any mark on the eyeball to measure the position of the cornea, and the measured position and torsion angle of the cornea can be indicated.
摘要翻译：视频成像装置使用从成像光源发射到角膜的光获得角膜的眼球图像。基于获得的眼球图像，视频处理装置计算角膜相对于基准位置的X轴和Y轴移动量和扭转角度，并使坐标指示装置指示计算出的X和Y轴偏移量，轴偏移量和扭转角。通过这种布置，可以精确地检测和测量患者角膜的位置和扭转角度，而不在眼球上形成任何标记以测量角膜的位置，并且可以指示测量的角膜的位置和扭转角度。

100. 发明申请

US20020065511A1 Patient stabilization system 审中-公开
标题翻译：患者稳定系统
公开(公告)号：US20020065511A1
公开(公告)日：2002-05-30
申请号：US09727080
申请日：2000-11-29
发明人： Ricardo Guimaraes , Rod Ross
IPC分类号： A61B018/20
CPC分类号： A61F9/00804 , A61B34/20 , A61B90/36 , A61B2034/2072 , A61F2009/00846 , A61F2009/00872
摘要： A system for detecting a movement of a patient's head during an ophthalmic procedure. The system may include one or more transmitters that can be attached to the head of the patient. The transmitters can transmit signals that are detected by corresponding receivers. The receivers may be located on a laser assembly that directs a laser beam onto the cornea of the patient. The system may have an indicator that is activated when one or more signals are not received, indicating that the patient's head has moved outside a predetermined range.
摘要翻译：一种用于在眼科手术期间检测患者头部的运动的系统。该系统可以包括可附接到患者头部的一个或多个发射器。发射机可以传输由相应接收机检测到的信号。接收器可以位于激光组件上，该激光组件将激光束引导到患者的角膜上。系统可以具有当未接收到一个或多个信号时被激活的指示符，指示患者的头已经移动超出预定范围。

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