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91. 发明申请

US20110047535A1 Dynamic Configuration System 有权
标题翻译：动态配置系统
公开(公告)号：US20110047535A1
公开(公告)日：2011-02-24
申请号：US12771807
申请日：2010-04-30
申请人： Sarabhaiah Polakam , Darin Michael DeFer , John Andres Lozes , Christpher Alan Moore , Peter Anthony Tavormina , Ying Huang
发明人： Sarabhaiah Polakam , Darin Michael DeFer , John Andres Lozes , Christpher Alan Moore , Peter Anthony Tavormina , Ying Huang
IPC分类号： G06F9/44
CPC分类号： G06F9/542 , G06F8/70 , G06F2209/543
摘要： Systems and methods are illustrated that relate to a dynamic configuration of rules (e.g., business rules, presentation rules, etc.) in a virtual machine environment. Moreover, the rules may be updated and used with an application that is running on a virtual machine without requiring the virtual machine to be stopped and started (i.e., restarted). Furthermore, aspects of the disclosure describe managing the visibility of dynamic rules to various applications running on the same virtual machine.
摘要翻译：示出了与虚拟机环境中的规则（例如，业务规则，呈现规则等）的动态配置相关的系统和方法。此外，可以更新规则并与虚拟机上运行的应用程序一起使用，而不需要停止并启动虚拟机（即重新启动）。此外，本公开的方面描述了将动态规则的可视性管理到在相同虚拟机上运行的各种应用。

92. 发明申请

US20110022704A1 METHOD AND SYSTEM FOR COLLECTING INFORMATION ON A USER VISIT 审中-公开
标题翻译：收集用户访问信息的方法和系统
公开(公告)号：US20110022704A1
公开(公告)日：2011-01-27
申请号：US12826753
申请日：2010-06-30
申请人： Ning Duan , Ying Huang , Pei Sun , Wei Sun , Jian Ming Zhang
发明人： Ning Duan , Ying Huang , Pei Sun , Wei Sun , Jian Ming Zhang
IPC分类号： G06F15/173
CPC分类号： H04L67/22 , G06F16/957
摘要： The present invention provides a computer implemented method and system for collecting information on a user visit for web analytics. An information collection module is sent to a client in response to a page opening request from the client. The information collection module is for collecting additional information on user visit of the client. Additional information on user visit and basic information on user visit of the client is obtained from a web service request. A web beacon request is generated based on the obtained information. The invention adopts a non-intrusive information collection manner that does not require modifying code of a web application and thus, is much simpler, feasible, and cost-effective than prior art. Further, centralized collection and management for the information on user visit can be implemented. Thus, it is more flexible and convenient for maintenance and optimization.
摘要翻译：本发明提供了一种计算机实现的方法和系统，用于收集关于网页分析的用户访问的信息。响应于来自客户端的打开页面请求，向客户端发送信息收集模块。信息收集模块用于收集客户端用户访问的附加信息。有关用户访问的其他信息和客户端用户访问的基本信息，请从Web服务请求获取。基于获得的信息生成网络信标请求。本发明采用不需要修改web应用的代码的非侵入式信息收集方式，因此比现有技术更简单，可行，成本更高。此外，可以实现对用户访问信息的集中采集和管理。因此，维护和优化更灵活方便。

93. 发明授权

US07855748B2 Reference voltage generation in imaging sensors 失效
标题翻译：成像传感器中的参考电压产生
公开(公告)号：US07855748B2
公开(公告)日：2010-12-21
申请号：US11949542
申请日：2007-12-03
申请人： Giuseppe Rossi , Laurent Blanquart , Ying Huang
发明人： Giuseppe Rossi , Laurent Blanquart , Ying Huang
IPC分类号： H04N5/225
CPC分类号： H03M1/662 , H03M1/76 , H04N5/335 , H04N5/3698
摘要： The claimed subject matter provides systems and/or methods that facilitate generating and/or maintaining low noise reference voltages for CMOS imaging System-on-Chip (iSoC) sensors. A primary reference voltage can be generated utilizing a low noise bandgap. Further, the primary reference voltage can be filtered via a low pass filter. The filtered, primary reference voltage can thereafter be distributed to a plurality of isolated domains. Each of the isolated domains can generate an independent set of reference voltages based upon the filtered, primary reference voltage. Moreover, subsets of these reference voltages can be employed by programmable digital to analog converters (DACs). Each of the reference voltages can be isolated from switching noise and/or clock glitches generated within each domain. Further, each DAC output can be buffered to have adequately low impedance with appropriate drive capability and requisite signal swing.
摘要翻译：所要求保护的主题提供了有助于为CMOS成像片上系统（iSoC）传感器产生和/或维持低噪声参考电压的系统和/或方法。可以利用低噪声带隙产生主参考电压。此外，可以通过低通滤波器对初级参考电压进行滤波。滤波后的主参考电压此后可以分配到多个隔离域。每个隔离域可以基于滤波的主要参考电压产生独立的一组参考电压。此外，这些参考电压的子集可由可编程数模转换器（DAC）采用。每个参考电压可以与每个域内产生的开关噪声和/或时钟毛刺隔离。此外，每个DAC输出可以被缓冲以具有适当的低阻抗，具有适当的驱动能力和必要的信号摆幅。

94. 发明申请

US20100178294A1 MACROCYCLIC BETA-SECRETASE INHIBITORS 有权
标题翻译：大分子β-分泌酶抑制剂
公开(公告)号：US20100178294A1
公开(公告)日：2010-07-15
申请号：US12571840
申请日：2009-10-01
申请人： Andrew W. Stamford , Ying Huang , Guoqing Li , Corey O. Strickland , Johannes H. Voigt
发明人： Andrew W. Stamford , Ying Huang , Guoqing Li , Corey O. Strickland , Johannes H. Voigt
IPC分类号： A61K39/395 , C07D413/06 , A61K31/496 , C07D498/04 , A61P25/28 , A61P25/00
CPC分类号： C07D498/04 , C07D413/06
摘要： Disclosed are novel compounds of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, R3, n and X are as defined in the specification. Also disclosed are pharmaceutical compositions comprising the compounds of formula I.Also disclosed are methods of treating cognitive or neurodegenerative diseases such as Alzheimer's disease.Also disclosed are methods of treating a cognitive or neurodegenerative disease comprising administering to a patient I need of such treatment a combination of at least one compound of formula I and at least one compound selected from the group consisting of β-secretase inhibitors other than those of formula I, HMG-CoA reductase inhibitors, gamma-secretase inhibitors, non-steroidal anti-inflammatory agents, N-methyl-D-aspartate receptor antagonists, cholinesterase inhibitors and anti-amyloid antibodies.
摘要翻译：公开了下式的新化合物或其药学上可接受的盐或溶剂化物，其中R1，R2，R3，n和X如说明书中所定义。还公开了包含式I化合物的药物组合物。还公开了治疗认知或神经变性疾病如阿尔茨海默病的方法。还公开了治疗认知或神经退行性疾病的方法，包括向需要这种治疗的患者施用至少一种式I化合物和至少一种选自除了那些的那些之外的其他化合物式I，HMG-CoA还原酶抑制剂，γ-分泌酶抑制剂，非甾体抗炎剂，N-甲基-D-天冬氨酸受体拮抗剂，胆碱酯酶抑制剂和抗淀粉样蛋白抗体。

95. 发明授权

US07686934B2 Three dimensional dielectrophoretic separator and methods of use 有权
标题翻译：三维介电泳分离器及其使用方法
公开(公告)号：US07686934B2
公开(公告)日：2010-03-30
申请号：US11638093
申请日：2006-12-12
申请人： Dalibor Hodko , Ying Huang , Daniel D. Smolko
发明人： Dalibor Hodko , Ying Huang , Daniel D. Smolko
IPC分类号： G01N27/447 , G01N27/453
CPC分类号： G01N27/447 , B03C5/005 , B03C5/026
摘要： Devices and methods for performing separation of cell particles by dielectrophoresis in three dimensions. In one embodiment the device comprises a flow chamber having microfabricated chip with a plurality of vertical and horizontal electrodes, which may be coated with a protective layer to prevent direct contact between any electrode and a sample. The horizontal electrodes are in electrical communication with a DC or an AC power source, while the vertical electrodes are in electrical communication with an AC power source.
摘要翻译：用于通过介电电泳在三维中进行细胞颗粒分离的装置和方法。在一个实施例中，该装置包括具有多个垂直和水平电极的微加工芯片的流动室，其可以涂覆有保护层，以防止任何电极和样品之间的直接接触。水平电极与DC或AC电源电连通，而垂直电极与AC电源电连通。

96. 发明申请

US20080274959A1 Actinomadura Chromoprotein, Apoprotein and Gene Cluster 审中-公开
标题翻译：放线菌素蛋白，载脂蛋白和基因簇
公开(公告)号：US20080274959A1
公开(公告)日：2008-11-06
申请号：US11794068
申请日：2005-12-16
申请人： Bradley A. Haltli , Haiyin He , Ying Huang , Sridhar Krishna Rabindran , Jiang Wu , Min He
发明人： Bradley A. Haltli , Haiyin He , Ying Huang , Sridhar Krishna Rabindran , Jiang Wu , Min He
IPC分类号： A61K38/16 , C07H21/04 , C12N15/63 , C12N1/21 , C12N1/15 , C12P21/00 , C07H17/08 , C07K14/37 , G01N33/566 , C12N1/14 , G01N33/53 , A61P35/00
CPC分类号： C12N15/52
摘要： The present invention provides a chromoprotein produced by Actinomadura sp. 21G792, as well as amino acid and nucleic acid sequences of the apoprotein component of the chromoprotein and of components of the biosynthetic pathway for the chromophore. The present invention is useful for developing pharmaceutical and treating diseases such as cancer or bacterial infections.
摘要翻译：本发明提供由放线菌属（Actinomadura sp。）生产的色素蛋白 21G792，以及发色蛋白的脱辅基蛋白组分的氨基酸和核酸序列以及发色团的生物合成途径的组分。本发明可用于开发药物和治疗诸如癌症或细菌感染的疾病。

97. 发明申请

US20080218615A1 Apparatus and method for stabilizing image sensor black level 有权
标题翻译：用于稳定图像传感器黑色电平的装置和方法
公开(公告)号：US20080218615A1
公开(公告)日：2008-09-11
申请号：US11715808
申请日：2007-03-07
申请人： Ying Huang , Giuseppe Rossi , Roberto Marchesini , Qianjiang (Bob) Mao , John Wallner , John Richardson , Laurent Blanquart , Joey Shah
发明人： Ying Huang , Giuseppe Rossi , Roberto Marchesini , Qianjiang (Bob) Mao , John Wallner , John Richardson , Laurent Blanquart , Joey Shah
IPC分类号： H04N5/335
CPC分类号： H04N5/361 , H04N5/2176 , H04N5/3658
摘要： A black clamp stabilization circuit for an image sensor utilizes a mixed-signal SoC block comprising sub-blocks to dynamically and precisely adjust the black level based on comparison to a reference black level. The black level adjustments include a first level regulation using digital control of an analog signal in a feedback loop that includes a programmable gain amplifier and high-resolution A/D converter. By applying the black clamping in the analog domain, dynamic range is extended. Additional black level regulation is subsequently performed in the digital domain to differentially eliminate line noise and column noise generated within the imaging System-on-Chip. By providing information between the sub-blocks, the algorithms can converge more quickly. The technique enables multiple signal paths to separately handle individual colors and to increase imaging data throughput.
摘要翻译：用于图像传感器的黑色钳位稳定电路利用包括子块的混合信号SoC块，以基于与参考黑色电平的比较来动态且精确地调整黑色电平。黑电平调节包括使用包括可编程增益放大器和高分辨率A / D转换器的反馈环路中的模拟信号的数字控制的第一电平调节。通过在模拟域中施加黑色钳位，可以延长动态范围。随后在数字域中执行额外的黑电平调节，以差分消除在成像片上系统中产生的线噪声和列噪声。通过在子块之间提供信息，算法可以更快地收敛。该技术使得多个信号路径可以分开处理各种颜色并增加成像数据吞吐量。

98. 发明申请

US20080183514A1 System and Methods for Using Solution Building Blocks 审中-公开
标题翻译：使用解决方案构建块的系统和方法
公开(公告)号：US20080183514A1
公开(公告)日：2008-07-31
申请号：US11668141
申请日：2007-01-29
申请人： Ingrid Moulckers , Robert A. Hood , Denise E. Frey , Ying Huang , Westley M. Clavey , Stephen E. Bello
发明人： Ingrid Moulckers , Robert A. Hood , Denise E. Frey , Ying Huang , Westley M. Clavey , Stephen E. Bello
IPC分类号： G06F9/44
CPC分类号： G06Q30/016 , G06F8/36 , G06Q99/00
摘要： A method for creating and delivering customer solutions includes analyzing a customer's requirements; selecting at least one solution building block as part of a customer solution; and delivering at least one customer solution. The at least one solution building block comprises a preconfigured bundle of at least one asset comprising at least one of a hardware product, software product, service, or another solution building block. The at least one solution building block has been at least one of previously tested or successfully deployed in a customer environment for solving a business, infrastructure, or application problem.
摘要翻译：创建和交付客户解决方案的方法包括分析客户的要求; 选择至少一个解决方案构建块作为客户解决方案的一部分; 并提供至少一个客户解决方案。所述至少一个解决方案构建块包括至少一个资产的预配置捆绑包括硬件产品，软件产品，服务或另一解决方案构建块中的至少一个。至少一个解决方案构建块至少是先前测试或成功部署在客户环境中以解决业务，基础架构或应用程序问题中的至少一个。

99. 发明申请

US20080019978A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF 有权
标题翻译：含氮杂环化合物及其使用方法
公开(公告)号：US20080019978A1
公开(公告)日：2008-01-24
申请号：US11771538
申请日：2007-06-29
申请人： Anandan Palani , Jing Su , Dong Xiao , Xianhai Huang , Ashwin Rao , Xiao Chen , Haiqun Tang , Jun Qin , Ying Huang , Robert Aslanian , Brian McKittrick , Sylvia Degrado
发明人： Anandan Palani , Jing Su , Dong Xiao , Xianhai Huang , Ashwin Rao , Xiao Chen , Haiqun Tang , Jun Qin , Ying Huang , Robert Aslanian , Brian McKittrick , Sylvia Degrado
IPC分类号： A61K31/519 , A61K31/397 , A61K31/56 , A61K31/60 , A61K38/16 , A61K39/395 , A61P1/00 , A61P11/00 , A61P3/00 , A61P3/10 , A61P35/00 , A61P9/00 , C07D239/70
CPC分类号： C07D491/04 , C07D471/04
摘要： The present invention provides compounds of Formula (I): and pharmaceutically acceptable salts, solvates, esters, and tautomers thereof, wherein: Q is selected from the group consisting of: and L is selected from the group consisting of: pharmaceutically compositions comprising one or more compounds of formula (I), and methods of using the compounds of formula (I).
摘要翻译：本发明提供式（I）的化合物及其药学上可接受的盐，溶剂合物，酯和互变异构体，其中：Q选自：和L选自：药物组合物，其包含一种或多种更多的式（I）化合物和使用式（I）化合物的方法。

100. 发明申请

US20070144918A1 Electrochemical test strip 有权
标题翻译：电化学试片
公开(公告)号：US20070144918A1
公开(公告)日：2007-06-28
申请号：US11640886
申请日：2006-12-19
申请人： Yu-Sen Hsu , Ying Huang , Thomas Shen
发明人： Yu-Sen Hsu , Ying Huang , Thomas Shen
IPC分类号： G01N27/26
CPC分类号： G01N27/3272 , G01N33/48771
摘要： An electrochemical test system comprising an electrochemical test strip capable of initiating an instrument, determining if it is inserted into a correct position of the instrument, a sample is injected into a reaction region of the electrochemical test strip, and the sample covers the reaction region properly. The electrochemical test strip includes an insulating substrate, an electrode system, and an insulating layer. The electrode system includes a resistor, a set of measurement electrodes which includes a reference electrode and a working electrode insulated from each other, and a set of identifying electrodes which includes first and second identifying electrodes connected through the resistor. A method for detecting a sample includes the steps of inserting the electrochemical test strip into a measurement instrument, providing the sample in the reaction region, and applying a voltage between the reference electrode and the working electrode, and measuring a current corresponding to the voltage.
摘要翻译：一种电化学测试系统，包括能够启动仪器的电化学测试条，确定其是否被插入仪器的正确位置，将样品注入到电化学测试条的反应区域中，并且样品适当地覆盖反应区域。电化学测试条包括绝缘基板，电极系统和绝缘层。电极系统包括电阻器，包括参考电极和彼此绝缘的工作电极的一组测量电极，以及包括通过电阻器连接的第一和第二识别电极的一组识别电极。检测样品的方法包括以下步骤：将电化学测试条插入测量仪器中，在反应区域中提供样品，并在参比电极和工作电极之间施加电压，并测量与电压相对应的电流。

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