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    • 92. 发明申请
    • BIOMARKERS FOR TRICHOGENICITY
    • 生物标志物的生物多样性
    • US20100291580A1
    • 2010-11-18
    • US12808623
    • 2008-12-18
    • Satish ParimooHonghua YangYing HomanWei ChenYing ZhengKurt Stenn
    • Satish ParimooHonghua YangYing HomanWei ChenYing ZhengKurt Stenn
    • C12Q1/68G01N33/566C12N15/79
    • C12Q1/6881C12Q2600/178G01N33/6881G01N33/6893G01N2500/10
    • Biomarkers for identifying trichogenic cells have been identified. The biomarkers include microRNA as wells as mRNA and proteins. Certain biomarkers are upregulated in trichogenic cells compared to non-trichogenic cells; whereas, other biomarkers are down-regulated in trichogenic cells compared to non-trichogenic cells. The cells can be dermal cells, epidermal cells, or a combination thereof. Preferably the cells are mammalian, more preferably the cells are human. One embodiment provides a method for selecting trichogenic cells by assaying the cells for expression of one or more biomarkers for trichogenicity, and selecting the cells having increased expression of the one or more biomarkers relative to a control, wherein increased expression of the a biomarker in the cells is indicative of trichogenicity. Preferably, the one or more biomarkers are selected from the group consisting of hsa-miR-200c, hsa-miR-205, hsa-miR-200a*, hsa-miR-200a, hsa-miR-141, hsa-miR-182, DEPDC1, hFLEG1, ESM1, TOME-1, THBD and combinations thereof.
    • 已鉴定出用于鉴定发生细胞的生物标志物。 生物标志物包括微RNA作为mRNA和蛋白质的孔。 与非致毛细胞相比,某些生物标志物在致毛细胞中上调; 而与非致毛细胞相比,其他生物标志物在发育细胞中下调。 细胞可以是真皮细胞,表皮细胞或其组合。 优选地,细胞是哺乳动物,更优选细胞是人。 一个实施方案提供了一种用于通过测定细胞用于表达一种或多种针刺性生物标志物的细胞并选择相对于对照而增加一种或多种生物标志物表达的细胞的方法,其中所述生物标志物在 细胞表示毛发性。 优选地,一种或多种生物标志物选自hsa-miR-200c,hsa-miR-205,hsa-miR-200a *,hsa-miR-200a,hsa-miR-141,hsa-miR-182 ,DEPDC1,hFLEG1,ESM1,TOME-1,THBD及其组合。
    • 93. 发明申请
    • TEMPERATURE BASED WHITE POINT CONTROL IN BACKLIGHTS
    • 背光温度基于白点控制
    • US20100244701A1
    • 2010-09-30
    • US12410164
    • 2009-03-24
    • Cheng ChenJun QiJohn Z. ZhongVictor H. YinWei Chen
    • Cheng ChenJun QiJohn Z. ZhongVictor H. YinWei Chen
    • H01J61/52
    • G02F1/133603G09G3/3413G09G3/3426G09G2320/041G09G2320/048G09G2320/0626G09G2320/0666G09G2360/145
    • Systems, methods, and devices are provided for maintaining a target white point on a light emitting diode based backlight. In one embodiment, the backlight may include two or more strings of light emitting diodes, each driven at a respective driving strength. Each string may include light emitting diodes from a different color bin, and the respective driving strengths may be adjusted, for example, through pulse width modulation or amplitude modulation, to maintain the target white point. In certain embodiments, the driving strengths may be adjusted to compensate for shifts in the white point that may occur due to temperature or aging. A controller may adjust the driving strengths based on feedback from a temperature sensor, from an optical sensor, from a user input, or from calibration data included within the backlight or system.
    • 提供了用于在基于发光二极管的背光源上维持目标白点的系统,方法和装置。 在一个实施例中,背光源可以包括两个或更多个发光二极管串,每个发光二极管以相应的驱动强度驱动。 每个串可以包括来自不同颜色仓的发光二极管,并且可以例如通过脉冲宽度调制或幅度调制来调整相应的驱动强度,以维持目标白点。 在某些实施例中,可以调整驱动强度以补偿由于温度或老化而可能发生的白点偏移。 控制器可以基于来自温度传感器的反馈,来自光学传感器,来自用户输入的反馈或来自包括在背光或系统内的校准数据来调整驱动强度。
    • 100. 发明申请
    • High efficiency synchronous reectifiers
    • 高效率同步再生器
    • US20100124086A1
    • 2010-05-20
    • US12313435
    • 2008-11-20
    • Wei Chen
    • Wei Chen
    • H02M7/217
    • H02M3/33592Y02B70/1475
    • Methods and circuits for synchronous rectifier control are disclosed herein. In one embodiment, a synchronous rectifier control circuit can include: (i) a first sense circuit to sense a voltage between first and second power terminals of a synchronous rectifier device prior to a turn-on of the device, where a timing of the turn-on of the synchronous rectifier device is adjustable using a first control signal generated from the first sense circuit; (ii) a second sense circuit configured to sense a voltage between the first and second power terminals after a turn-off of the device, where a timing of the turn-off of the device is adjustable using a second control signal generated from the second sense circuit; and (iii) a driver control circuit configured to receive the first and second control signals, and to generate therefrom a gate control signal configured to drive a control terminal of the synchronous rectifier device.
    • 本文公开了用于同步整流器控制的方法和电路。 在一个实施例中,同步整流器控制电路可以包括:(i)第一感测电路,用于在器件接通之前感测同步整流器件的第一和第二电源端子之间的电压,其中转向的定时 - 使用从第一感测电路产生的第一控制信号可调整同步整流器件; (ii)第二感测电路,被配置为在所述设备关闭之后感测所述第一和第二电源端子之间的电压,其中所述设备的关断定时可使用从所述第二控制信号产生的第二控制信号来调节 感应电路; 以及(iii)驱动器控制电路,被配置为接收所述第一和第二控制信号,并由其产生用于驱动所述同步整流装置的控制端的门控制信号。