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91. 发明申请

US20100022634A1 Laidlomycin compositions and methods 有权
标题翻译： Laidlomycin组合物和方法
公开(公告)号：US20100022634A1
公开(公告)日：2010-01-28
申请号：US12456300
申请日：2009-06-15
申请人： Steven Holmes , Janice Cacace
发明人： Steven Holmes , Janice Cacace
IPC分类号： A61K31/35 , A61P3/00
CPC分类号： A61K31/35 , A23K20/195 , A23K40/10 , A23K50/10
摘要： An animal feed additive composition comprises an effective amount of a laidlomycin, a carrier, magnesium sulfate, and silicon dioxide. Other embodiments include methods of making the animal feed additive compositions, and the use of a laidlomycin in the manufacture of an animal feed additive for increasing the efficiency of feed utilization and rate of weight gain in domestic animals.
摘要翻译：动物饲料添加剂组合物包含有效量的布洛霉素，载体，硫酸镁和二氧化硅。其他实施方案包括制备动物饲料添加剂组合物的方法，以及在生产动物饲料添加剂中使用布洛霉素以提高饲料利用效率和家畜体重增加率的方法。

92. 发明申请

US20070283073A1 Port adapter for high-bandwidth bus 有权
标题翻译：用于高带宽总线的端口适配器
公开(公告)号：US20070283073A1
公开(公告)日：2007-12-06
申请号：US11818006
申请日：2007-06-12
申请人： David Doak , Garry Epps , Guy Fedorkow , Mark Gustlin , Steven Holmes , Randall Johnson , Promode Nedungadi , Mohammed Tatar
发明人： David Doak , Garry Epps , Guy Fedorkow , Mark Gustlin , Steven Holmes , Randall Johnson , Promode Nedungadi , Mohammed Tatar
IPC分类号： G06F13/14
CPC分类号： H04L12/5692 , G06F13/387 , H04J3/1617 , Y10S370/912
摘要： A port adapter for connecting zero or more network interfaces to a host system having a SPI-4 bus is disclosed. The port adapter comprises zero or more network interfaces; a SPI-4 bus coupled to a host system to provide a communication channel between the host and the network interfaces; a control bus coupled to the host system for controlling and monitoring the port adapter; and interface logic that interfaces the SPI-4 bus and the control bus to the network interfaces. Methods are provided for selecting and using one of a small plurality of different packet formats for various networking technologies, so that the port adapter can hide details of the technology that it handles from the host system, and for operating the host system's SPI-4 bus at one of several speeds based on bandwidth requirements of the port adapter.
摘要翻译：公开了一种用于将零个或多个网络接口连接到具有SPI-4总线的主机系统的端口适配器。端口适配器包括零个或多个网络接口; 耦合到主机系统的SPI-4总线以在主机和网络接口之间提供通信信道; 耦合到所述主机系统的用于控制和监视所述端口适配器的控制总线; 以及将SPI-4总线和控制总线连接到网络接口的接口逻辑。提供了用于选择和使用用于各种联网技术的小的多种不同分组格式之一的方法，使得端口适配器可以隐藏其从主机系统处理的技术的细节，以及用于操作主机系统的SPI-4总线基于端口适配器的带宽要求，以几种速度之一。

93. 发明申请

US20070197405A1 MINERAL INSULATING OIL, A PROCESS FOR PREPARING A MINERAL INSULATING OIL, AND A PROCESS FOR USING A MINERAL INSULATING OIL 失效
标题翻译：矿物绝缘油，制备矿物绝缘油的方法和使用矿物绝缘油的方法
公开(公告)号：US20070197405A1
公开(公告)日：2007-08-23
申请号：US11466856
申请日：2006-08-24
申请人： Steven Holmes , Ronald Dever
发明人： Steven Holmes , Ronald Dever
IPC分类号： C10M169/04
CPC分类号： H01B3/22 , C10G2400/10 , C10M101/02 , C10M2203/1025 , C10M2203/1065 , C10M2207/026 , C10M2207/289 , C10M2215/064 , C10N2220/02 , C10N2240/201
摘要： The invention provides for a mineral insulating oil having a naphthenic base oil and a paraffinic base oil wherein the naphthenic base oil includes a ratio of total sulfur to basic nitrogen of less than about 80:1. The invention also provides for a mineral insulating oil having a naphthenic base oil, a paraffinic base oil, and an antioxidant agent wherein the naphthenic base oil includes a ratio of total sulfur to basic nitrogen of less than about 80:1. The invention also provides for a process for producing a mineral insulating oil including contacting a naphthenic base oil and a paraffinic base oil wherein the naphthenic base oil includes a ratio of total sulfur to basic nitrogen of less than about 80:1. The invention also provides for a process for producing a mineral insulating oil including contacting a naphthenic base oil, a paraffinic base oil, and an antioxidant agent wherein the naphthenic base oil includes a ratio of total sulfur to basic nitrogen of less than about 80:1.
摘要翻译：本发明提供一种具有环烷基油和石蜡基油的矿物绝缘油，其中环烷基油包括总硫与碱性氮的比例小于约80:1。本发明还提供了具有环烷基油，石蜡基油和抗氧化剂的矿物绝缘油，其中环烷基油包括总硫与碱性氮的比例小于约80:1。本发明还提供一种生产矿物绝缘油的方法，包括使环烷基油和石蜡基油接触，其中环烷基油包括总硫与碱性氮的比例小于约80:1。本发明还提供一种生产矿物绝缘油的方法，包括使环烷基油，石蜡基油和抗氧化剂接触，其中环烷基油包括总硫与碱性氮的比例小于约80:1 。

94. 发明申请

US20060160037A1 AUTOMATED SUB-FIELD BLADING FOR LEVELING OPTIMIZATION IN LITHOGRAPHY EXPOSURE TOOL 审中-公开
标题翻译：自动化的子场开采用于平面曝光工具中的优化优化
公开(公告)号：US20060160037A1
公开(公告)日：2006-07-20
申请号：US10905706
申请日：2005-01-18
申请人： Colin Brodsky , Scott Bukofsky , Steven Holmes
发明人： Colin Brodsky , Scott Bukofsky , Steven Holmes
IPC分类号： G03F7/20
CPC分类号： G03F7/70466
摘要： A method of exposing images on a wafer having varying topography during lithographic production of microelectronic devices. The method initially includes determining topography of a wafer, dividing the wafer into two or more separate regions based on the wafer topography, and determining desired focus distance for exposing a desired image on each of the separate regions of the wafer. The method then includes exposing a desired image on one of the regions of the wafer at the desired focus distance while blocking remaining regions and exposing a desired image on another of the regions of the wafer at the desired focus distance while blocking remaining regions. The desired focus distance may be different for each of the separate wafer regions.
摘要翻译：一种在微电子器件的光刻生产期间在具有变化的形貌的晶片上曝光图像的方法。该方法最初包括确定晶片的形貌，基于晶片形貌将晶片分成两个或更多个分离的区域，以及确定用于在晶片的每个分离区域上曝光所需图像的期望焦距。该方法然后包括以期望的聚焦距离在晶片的一个区域上曝光期望的图像，同时阻挡剩余的区域并且以期望的焦距在所需的聚焦距离的另一个区域上曝光期望的图像，同时阻挡剩余的区域。对于每个单独的晶片区域，期望的对焦距离可以是不同的。

95. 发明申请

US20060100467A1 Cycloalkane base oils, cycloalkane-base dielectric liquids made using cycloalkane base oils, and methods of making same 有权
标题翻译：环烷烃基油，使用环烷烃基油制备的环烷烃基介电液体及其制备方法
公开(公告)号：US20060100467A1
公开(公告)日：2006-05-11
申请号：US11153812
申请日：2005-06-15
申请人： Steven Holmes , John Powers , Michael Smith , Abraham Dekraker
发明人： Steven Holmes , John Powers , Michael Smith , Abraham Dekraker
IPC分类号： C10M105/04
CPC分类号： C10M105/04 , C10M2203/1065 , C10N2220/022 , C10N2240/201 , H01B3/22
摘要： Cycloalkane base oil, methods of making cycloalkane base oil, and dielectric liquid comprising cycloalkane base oil, the cycloalkane base oil comprising a quantity of isoparaffins and from 50 wt. % to 70 wt. % cycloalkanes having the formula CnH2n wherein n is from 15 to 30, said quantity of isoparaffins being less than 50 wt. % of said cycloalkane base oil.
摘要翻译：环烷烃基油，制备环烷烃基油的方法和包含环烷烃基油的介电液体，所述环烷烃基油包含一定数量的异链烷烃和50wt。％至70wt。具有式C n H 2n 2n的％环烷烃其中n为15至30，所述异链烷烃的量小于50wt。％的所述环烷烃基础油。

96. 发明申请

US20060100466A1 Cycloalkane base oils, cycloalkane-base dielectric liquids made using cycloalkane base oils, and methods of making same 审中-公开
标题翻译：环烷烃基油，使用环烷烃基油制备的环烷烃基介电液体及其制备方法
公开(公告)号：US20060100466A1
公开(公告)日：2006-05-11
申请号：US10983839
申请日：2004-11-08
申请人： Steven Holmes , John Powers , Michael Smith
发明人： Steven Holmes , John Powers , Michael Smith
IPC分类号： C10M105/04
CPC分类号： C10M105/04 , C10M169/04 , C10M2203/045 , C10M2203/06 , C10M2203/1065 , C10M2205/22 , C10M2207/026 , C10N2220/028 , C10N2230/04 , C10N2230/06 , C10N2230/52 , Y10T428/24901 , Y10T428/25 , Y10T428/31678
摘要： Cycloalkane base oil, methods of making cycloalkane base oil, and dielectric liquid containing such cycloalkane base oil is provided. The cycloalkane base oil contains a quantity of isoparaffins and from 50 wt. % to 70 wt. % cycloalkanes having the formula CnH2n wherein n is from 15 to 30, the quantity of isoparaffins being less than 50 wt. % of said cycloalkane base oil.
摘要翻译：提供了环烷烃基础油，制备环烷烃基础油的方法和含有这种环烷烃基础油的介电液体。环烷烃基油含有一定数量的异链烷烃和50wt。％至70wt。具有式C n H 2n 2n的％环烷烃其中n为15至30，异构烷烃的量小于50wt。％的所述环烷烃基础油。

97. 发明授权

US07035102B2 Apparatus for air cooling of an electronic device 有权
标题翻译：电子设备的空气冷却装置
公开(公告)号：US07035102B2
公开(公告)日：2006-04-25
申请号：US10815488
申请日：2004-03-31
申请人： Steven Holmes , Douglas L. Heirich
发明人： Steven Holmes , Douglas L. Heirich
IPC分类号： H05K7/20
CPC分类号： G06F1/20 , G06F1/206 , G06F1/3203 , Y02D10/16
摘要： An apparatus for air-cooling an electronic device is disclosed. A contoured panel channels a flow of air within the housing of an electronic device so as to channel the flow of air more directly over heat producing elements such as the microprocessor and peripheral cards. A sensor can also be employed to determine whether the panel is present and properly placed. If not, measures can be taken to reduce the heat generated by the heat producing elements. For example, a warning can be displayed, or the microprocessor can be instructed to enter sleep mode.
摘要翻译：公开了一种用于空气冷却电子设备的设备。轮廓面板在电子设备的壳体内引导空气流，以便将空气流更直接地传递到诸如微处理器和外围卡之类的制热元件上。还可以使用传感器来确定面板是否存在并被正确放置。如果没有，可以采取措施来减少由发热元件产生的热量。例如，可以显示警告，或者可以指示微处理器进入睡眠模式。

98. 发明申请

US20050149651A1 Port adapter for high-bandwidth bus 有权
标题翻译：用于高带宽总线的端口适配器
公开(公告)号：US20050149651A1
公开(公告)日：2005-07-07
申请号：US10680842
申请日：2003-10-06
申请人： David Doak , Garry Epps , Guy Fedorkow , Mark Gustlin , Steven Holmes , Randall Johnson , Promode Nedungadi , John Prokopik , Mohammed Tatar , Michael Taylor
发明人： David Doak , Garry Epps , Guy Fedorkow , Mark Gustlin , Steven Holmes , Randall Johnson , Promode Nedungadi , John Prokopik , Mohammed Tatar , Michael Taylor
IPC分类号： G06F3/00 , G06F13/38 , G06F13/40 , H04L12/28
CPC分类号： H04L12/5692 , G06F13/387 , H04J3/1617 , Y10S370/912
摘要： A port adapter for connecting zero or more network interfaces to a host system having a SPI-4 bus is disclosed. The port adapter comprises zero or more network interfaces; a SPI-4 bus coupled to a host system to provide a communication channel between the host and the network interfaces; a control bus coupled to the host system for controlling and monitoring the port adapter; and interface logic that interfaces the SPI-4 bus and the control bus to the network interfaces. Methods are provided for selecting and using one of a small plurality of different packet formats for various networking technologies, so that the port adapter can hide details of the technology that it handles from the host system, and for operating the host system's SPI-4 bus at one of several speeds based on bandwidth requirements of the port adapter.
摘要翻译：公开了一种用于将零个或多个网络接口连接到具有SPI-4总线的主机系统的端口适配器。端口适配器包括零个或多个网络接口; 耦合到主机系统的SPI-4总线以在主机和网络接口之间提供通信信道; 耦合到所述主机系统的用于控制和监视所述端口适配器的控制总线; 以及将SPI-4总线和控制总线连接到网络接口的接口逻辑。提供了用于选择和使用用于各种联网技术的小的多种不同分组格式之一的方法，使得端口适配器可以隐藏其从主机系统处理的技术的细节，并且用于操作主机系统的SPI-4总线基于端口适配器的带宽要求，以几种速度之一。

99. 发明授权

US09149456B2 Laidlomycin compositions and methods 有权
标题翻译： Laidlomycin组合物和方法
公开(公告)号：US09149456B2
公开(公告)日：2015-10-06
申请号：US12456300
申请日：2009-06-15
申请人： Steven Holmes , Janice Cacace
发明人： Steven Holmes , Janice Cacace
IPC分类号： A61K31/35 , A23K1/00 , A23K1/17 , A23K1/18
CPC分类号： A61K31/35 , A23K20/195 , A23K40/10 , A23K50/10
摘要： An animal feed additive composition comprises an effective amount of a laidlomycin, a carrier, magnesium sulfate, and silicon dioxide. Other embodiments include methods of making the animal feed additive compositions, and the use of a laidlomycin in the manufacture of an animal feed additive for increasing the efficiency of feed utilization and rate of weight gain in domestic animals.
摘要翻译：动物饲料添加剂组合物包含有效量的布洛霉素，载体，硫酸镁和二氧化硅。其他实施方案包括制备动物饲料添加剂组合物的方法，以及在生产动物饲料添加剂中使用布洛霉素以提高饲料利用效率和家畜体重增加率的方法。

100. 发明申请

US20130230540A1 COMPOSITIONS MONOVALENT FOR CD28 BINDING AND METHODS OF USE 审中-公开
标题翻译： CD28结合的组合物单一使用方法和使用方法
公开(公告)号：US20130230540A1
公开(公告)日：2013-09-05
申请号：US13545795
申请日：2012-07-10
申请人： Steven Holmes , Carrie Enever , Steven Grant , David Sansom
发明人： Steven Holmes , Carrie Enever , Steven Grant , David Sansom
IPC分类号： C07K16/28
CPC分类号： C07K16/2896 , C07K16/2818 , C07K2317/569
摘要： The disclosure relates to a monovalent polypeptide domain which specifically binds CD28, as well as to an antagonist of CD28, where the antagonist comprises a monovalent polypeptide domain which specifically binds CD28. This disclosure encompasses monovalent polypeptide domains comprising an antibody single variable domain that monovalently binds CD28. An antibody single variable domain that is monovalent for binding of CD28 can inhibit CD28 activity. In one aspect, a monovalent anti-CD28 antibody single variable domain consists of or comprises an antibody single variable domain that specifically binds and antagonizes the activity of CD28, in an aspect, without substantially agonizing CD28 activity. In another aspect, the monovalent anti-CD28 antibody single variable domain is a human antibody single variable domain. The disclosure further encompasses methods of antagonizing CD80 and/or CD86 interactions with CD28 in an individual and methods of treating diseases or disorders involving CD80 and/or CD86 interactions with CD28, the methods involving administering a monovalent anti-CD28 antibody single variable domain to the individual.
摘要翻译：本公开涉及特异性结合CD28的单价多肽结构域以及CD28拮抗剂，其中拮抗剂包含特异性结合CD28的单价多肽结构域。本公开内容涵盖包含单价结合CD28的抗体单可变结构域的单价多肽结构域。用于结合CD28的单价抗体单可变区可抑制CD28活性。在一个方面，单价抗CD28抗体单可变结构域由一个方面组成或包含特异性结合和拮抗CD28的活性的抗体单可变结构域，而不具有实质上激动的CD28活性。另一方面，单价抗CD28抗体单可变结构域是人抗体单可变结构域。本公开还包括在个体中拮抗CD80和/或CD86相互作用的方法以及涉及CD80和/或CD86与CD28相互作用的疾病或病症的方法，涉及向单克隆抗CD28抗体单可变结构域施用的方法个人。

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