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91. 发明授权

US08972228B2 Assessing intra-cardiac activation patterns 有权
标题翻译：评估心脏内激活模式
公开(公告)号：US08972228B2
公开(公告)日：2015-03-03
申请号：US13462480
申请日：2012-05-02
申请人： Subham Ghosh , Jeffrey M. Gillberg , Robert W. Stadler
发明人： Subham Ghosh , Jeffrey M. Gillberg , Robert W. Stadler
IPC分类号： G06G7/48 , A61B5/0408 , A61B5/0452 , A61B5/05 , A61B5/02 , A61B5/0402 , A61N1/04 , A61N1/362 , A61N1/368
CPC分类号： A61B5/04012 , A61B5/02 , A61B5/0402 , A61B5/04085 , A61B5/044 , A61B5/0452 , A61B5/05 , A61B5/742 , A61N1/0476 , A61N1/0484 , A61N1/3627 , A61N1/3682 , A61N1/3684
摘要： Techniques for evaluating cardiac electrical dyssynchrony are described. In some examples, an activation time is determined for each of a plurality of torso-surface potential signals. The dispersion or sequence of these activation times may be analyzed or presented to provide variety of indications of the electrical dyssynchrony of the heart of the patient. In some examples, the locations of the electrodes of the set of electrodes, and thus the locations at which the torso-surface potential signals were sensed, may be projected on the surface of a model torso that includes a model heart. The inverse problem of electrocardiography may be solved to determine electrical activation times for regions of the model heart based on the torso-surface potential signals sensed from the patient.
摘要翻译：描述了评估心脏电气不同步的技术。在一些示例中，为多个躯干表面电位信号中的每一个确定激活时间。可以分析或呈现这些激活时间的分散或序列以提供患者心脏的电不同步的各种指征。在一些示例中，电极组的电极的位置以及因此感测躯干表面电位信号的位置可以投影在包括模型心脏的模型躯干的表面上。可以基于从患者感测到的躯干表面电位信号来解决心电图的逆问题，以确定模型心脏区域的电激活时间。

92. 发明授权

US08750976B2 Implanted multichamber cardiac device with selective use of reliable atrial information 有权
标题翻译：植入式多室心脏装置可选择性使用可靠的心房信息
公开(公告)号：US08750976B2
公开(公告)日：2014-06-10
申请号：US13038664
申请日：2011-03-02
申请人： Robert W. Stadler , Mark L. Brown
发明人： Robert W. Stadler , Mark L. Brown
IPC分类号： A61B5/04 , A61N1/00
CPC分类号： A61N1/3622 , A61B5/046 , A61B5/0464 , A61B5/686 , A61B5/7221 , A61B5/7282 , A61N1/3704
摘要： An implantable medical device acquires a first cardiac signal in a first heart chamber and a second cardiac signal in a second heart chamber. The device determines if the first signal is unreliable. In response to determining the first signal to be unreliable, the device switches from a first cardiac arrhythmia detection mode of operation to a second cardiac arrhythmia detection mode of operation, the first detection mode requiring the use of both the first cardiac signal and the second cardiac signal and the second detection mode requiring the use of the second cardiac signal and not requiring the use of the first cardiac signal.
摘要翻译：可植入医疗装置获取第一心室中的第一心脏信号和第二心室中的第二心脏信号。设备确定第一个信号是否不可靠。响应于确定第一信号不可靠，设备从第一心律失常检测操作模式切换到第二心律失常检测操作模式，第一检测模式需要使用第一心脏信号和第二心脏信号和第二检测模式，需要使用第二心脏信号，并且不需要使用第一心脏信号。

93. 发明授权

US08615298B2 Criteria for optimal electrical resynchronization derived from multipolar leads or multiple electrodes during biventricular pacing 有权
公开(公告)号：US08615298B2
公开(公告)日：2013-12-24
申请号：US13464215
申请日：2012-05-04
申请人： Subham Ghosh , Robert W. Stadler
发明人： Subham Ghosh , Robert W. Stadler
IPC分类号： A61N1/365
CPC分类号： A61N1/3686 , A61N1/3622 , A61N1/3627 , A61N1/368 , A61N1/3684 , A61N1/371
摘要： Generally, the disclosure is directed one or more methods or systems of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes. Pacing using the right ventricular electrode and a first one of the left ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Pacing using the right ventricular electrode and a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Employing sums of the measured activation times to select one of the left ventricular electrodes for delivery of subsequent pacing pulses.

94. 发明授权

US08521275B2 Method of dual EGM sensing and heart rate estimation in implanted cardiac devices 有权
标题翻译：植入心脏装置中双重EGM感测和心率估计的方法
公开(公告)号：US08521275B2
公开(公告)日：2013-08-27
申请号：US13080820
申请日：2011-04-06
申请人： Robert W. Stadler , Carissa Lynn Bellardine Black
发明人： Robert W. Stadler , Carissa Lynn Bellardine Black
IPC分类号： A61N1/00 , A61B5/02 , A61B5/04
CPC分类号： A61B5/04525 , A61B5/02438 , A61B5/0464 , A61B5/686 , A61B5/7203 , A61N1/3622 , A61N1/3962
摘要： A method and apparatus for monitoring a patient's heart rate sense first cardiac events in a heart chamber using a first cardiac electrode pair and sense second cardiac events in the heart chamber using a second cardiac electrode pair. The method includes estimating a first heart rate using the first cardiac events, comparing the first heart rate to a heart rate threshold and estimating a second heart rate using the second cardiac events in response to the first heart rate exceeding the heart rate threshold, determining whether the second cardiac events are unreliable, and setting the second heart rate equal to the first heart rate in response to the second cardiac events being unreliable.
摘要翻译：用于监测患者心率的方法和装置使用第一心脏电极对感测心室中的第一心脏事件，并使用第二心电极对感测心室中的第二心脏事件。该方法包括使用第一心脏事件估计第一心率，将第一心率与心率阈值进行比较，并且响应于超过心率阈值的第一心率估计使用第二心脏事件的第二心率，确定是否第二心脏事件是不可靠的，并且响应于第二心脏事件不可靠而将第二心率设定为等于第一心率。

95. 发明申请

US20130218225A1 CRITERIA FOR OPTIMAL ELECTRICAL RESYNCHRONIZATION DERIVED FROM MULTIPOLAR LEADS OR MULTIPLE ELECTRODES DURING BIVENTRICULAR PACING 有权
公开(公告)号：US20130218225A1
公开(公告)日：2013-08-22
申请号：US13464228
申请日：2012-05-04
申请人： Subham Ghosh , Robert W. Stadler
发明人： Subham Ghosh , Robert W. Stadler
IPC分类号： A61N1/362
CPC分类号： A61N1/3686 , A61N1/3622 , A61N1/3627 , A61N1/368 , A61N1/3684 , A61N1/371
摘要： Generally, the disclosure is directed one or more methods or systems of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes. Pacing using the right ventricular electrode and a first one of the left ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Pacing using the right ventricular electrode and a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Employing sums of the measured activation times to select one of the left ventricular electrodes for delivery of subsequent pacing pulses.

96. 发明申请

US20130218223A1 CRITERIA FOR OPTIMAL ELECTRICAL RESYNCHRONIZATION DERIVED FROM MULTIPOLAR LEADS OR MULTIPLE ELECTRODES DURING BIVENTRICULAR PACING 有权
公开(公告)号：US20130218223A1
公开(公告)日：2013-08-22
申请号：US13464181
申请日：2012-05-04
申请人： Subham Ghosh , Robert W. Stadler
发明人： Subham Ghosh , Robert W. Stadler
IPC分类号： A61N1/362
CPC分类号： A61N1/3686 , A61N1/3622 , A61N1/3627 , A61N1/368 , A61N1/3684 , A61N1/371
摘要： Generally, the disclosure is directed one or more methods or systems of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes. Pacing using the right ventricular electrode and a first one of the left ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Pacing using the right ventricular electrode and a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Employing sums of the measured activation times to select one of the left ventricular electrodes for delivery of subsequent pacing pulses.

97. 发明申请

US20130110191A1 CARDIAC RESYNCHRONIZATION THERAPY LOSS DIAGNOSTICS 有权
标题翻译： CARDIAC RESYNCHRONIZATION治疗失败诊断
公开(公告)号：US20130110191A1
公开(公告)日：2013-05-02
申请号：US13297104
申请日：2011-11-15
申请人： Sean R. Landman , Robert W. Stadler
发明人： Sean R. Landman , Robert W. Stadler
IPC分类号： A61N1/37
CPC分类号： A61N1/37282 , A61N1/3622 , A61N1/3627 , A61N1/3682 , A61N1/37235
摘要： In some examples, an IMD provides CRT data that indicates an amount of time that CRT was not delivered by the IMD, such as the % CRT. In some examples, a CRT loss diagnosis module apportions the amount of time that CRT was not delivered amongst predetermined reasons for loss of CRT based on the CRT data and sensed cardiac data from the IMD. An external computing device may present a representation of the apportionment to a user, e.g., a clinician. The external computing device may also analyze the apportionment, and recommend programming changes for the delivery of CRT by the IMD based on the analysis.
摘要翻译：在一些示例中，IMD提供CRT数据，其指示CRT未由IMD递送的时间量，例如％CRT。在一些示例中，CRT损失诊断模块基于CRT数据和来自IMD的感测的心脏数据来分配在CRT的丢失的预定原因之间没有输送CRT的时间量。外部计算设备可以向用户（例如临床医师）呈现分配的表示。外部计算设备还可以分析分析，并且基于分析推荐由IMD传送CRT的编程改变。

98. 发明授权

US08406872B2 Method and apparatus for detecting and discriminating tachycardia 有权
标题翻译：用于检测和辨别心动过速的方法和装置
公开(公告)号：US08406872B2
公开(公告)日：2013-03-26
申请号：US12768905
申请日：2010-04-28
申请人： Robert W. Stadler , Xusheng Zhang
发明人： Robert W. Stadler , Xusheng Zhang
IPC分类号： A61N1/00
CPC分类号： A61N1/3956 , A61B5/0464 , A61B5/7203 , A61N1/3621
摘要： A medical device and associated method for discriminating cardiac events includes determining whether a cardiac evidence counter is greater than a predetermined detection threshold, advancing from a concerned state to a convinced state in response to the evidence counter being greater than the predetermined detection threshold, determining whether a reduction in the cardiac evidence counter occurs while in the convinced state, determining whether one of a first rate corresponding to the first sensing vector and a second rate corresponding to the second sensing vector is less than a predetermined rate limit, and determining whether to advance from the convinced state to one of a therapy delivery state, the concerned state and the unconcerned state in response to determining whether one of the first rate and the second rate is less than a predetermined rate limit.
摘要翻译：用于鉴别心脏事件的医疗装置和相关联的方法包括：确定心脏证据计数器是否大于预定检测阈值，响应于证据计数器大于预定检测阈值，从有关状态进入确信状态，确定是否在令人信服的状态下，发生心脏证据计数器的减少，确定对应于第一感测向量的第一速率和对应于第二感测向量的第二速率中的一个是否小于预定速率限制，并且确定是否前进响应于确定第一速率和第二速率之一是否小于预定速率限制，从相信状态到治疗传递状态之一，相关状态和不关心状态。

99. 发明授权

US08401646B2 Method and apparatus to determine the relative energy expenditure for a plurality of pacing vectors 有权
标题翻译：确定多个起搏向量的相对能量消耗的方法和装置
公开(公告)号：US08401646B2
公开(公告)日：2013-03-19
申请号：US13194100
申请日：2011-07-29
申请人： Robert W. Stadler , Wade M. Demmer , Todd J. Sheldon
发明人： Robert W. Stadler , Wade M. Demmer , Todd J. Sheldon
IPC分类号： A61B1/00
CPC分类号： A61N1/3712 , A61N1/3622 , A61N1/3686 , A61N1/3708
摘要： A medical device system determines and displays relative energy expenditure information for programmable parameter values. The system establishes a programmable parameter and multiple values of the parameter to be compared. A module performs a measurements for each of the multiple values and related to energy expenditure of a battery of an implantable medical device when operating according to each of the multiple parameter values. An energy expenditure for each of the values is computed using the measurements, and a graphical user interface is generated for displaying information corresponding to the computed energy expenditure for multiple parameter values.
摘要翻译：医疗设备系统确定并显示可编程参数值的相对能量消耗信息。系统建立可编程参数和要比较的参数的多个值。当根据多个参数值中的每个参数值进行操作时，模块对可植入医疗装置的电池的能量消耗进行测量。使用测量来计算每个值的能量消耗，并且生成用于显示与多个参数值的计算能量消耗相对应的信息的图形用户界面。

100. 发明授权

US08401629B2 Method and apparatus for detecting and discriminating tachycardia 有权
标题翻译：用于检测和辨别心动过速的方法和装置
公开(公告)号：US08401629B2
公开(公告)日：2013-03-19
申请号：US12768892
申请日：2010-04-28
申请人： Robert W. Stadler , Xusheng Zhang
发明人： Robert W. Stadler , Xusheng Zhang
IPC分类号： A61B5/04
CPC分类号： A61B5/0464 , A61B5/0245 , A61B5/7203 , A61N1/3622
摘要： A medical device and associated method for discriminating cardiac events includes determining whether a cardiac evidence counter is greater than a predetermined detection threshold, determining whether to advance from a current state to a next state in response to the evidence counter being greater than the predetermined detection threshold, determining whether advancing from a previous state to the current state occurred while in one of a low variability mode and a high variability mode during the previous state, and determining whether to advance from the current state to a previous state in response to determining whether advancing from a previous state to the current state occurred while operating in one of a low variability mode and a high variability mode during the previous state.
摘要翻译：用于鉴别心脏事件的医疗装置和相关联的方法包括确定心脏证据计数器是否大于预定检测阈值;响应于证据计数器大于预定检测阈值来确定是否从当前状态提前到下一状态在先前状态下，确定是否从先前状态进入到当前状态，同时以低可变性模式和高可变性模式之一发生，并且响应于是否前进而确定是否从当前状态前进到先前状态在先前状态期间以低变异性模式和高可变性模式之一操作时发生从先前状态到当前状态。

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