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    • 96. 发明授权
    • Epitaxial wafer and method for producing same
    • 外延晶片及其制造方法
    • US07648576B2
    • 2010-01-19
    • US10596280
    • 2004-12-10
    • Yasuo FukudaMakoto TakemuraKoichi Okuda
    • Yasuo FukudaMakoto TakemuraKoichi Okuda
    • C30B5/00H01L21/311
    • H01L21/02052H01L21/02008H01L21/02381H01L21/02532H01L21/02658H01L21/302Y10S438/905Y10S438/913
    • After cleaning the front and back sides of a silicon wafer with a liquid SC-1 and liquid SC-2, the front and back sides of the silicon wafer are cleaned with an HF solution to be water-repellent surfaces. Following that, an epitaxial layer of silicon is formed on the front side. Consequently, there can be reduced stacking faults after formation of the epitaxial layer and occurrence of cloud on the back side. Alternatively, the front and back sides of a silicon wafer are cleaned with the liquid SC-1 and liquid SC-2, and then the back side of the silicon wafer is cleaned with an HF solution to be a water-repellent surface while the front side is cleaned with purified water to be a hydrophilic surf ace. Following that, an epitaxial layer of silicon is formed on the front side. Consequently, there can be reduced mounds on the front side and occurrence of cloud on the back side.
    • 用液体SC-1和液体SC-2清洗硅晶片的正面和背面后,用HF溶液清洗硅晶片的正面和背面以防水表面。 之后,在正面形成硅外延层。 因此,在形成外延层之后可以减少堆垛层错,并且在背面发生云。 或者,用液体SC-1和液体SC-2清洗硅晶片的正面和背面,然后用HF溶液将硅晶片的背面清洗成防水表面,而前面 侧面用净化水清洗成亲水冲浪。 之后,在正面形成硅外延层。 因此,前侧可能有减少的土堆和背面出现云。
    • 97. 发明申请
    • FLUOROALKYLPYRROLIDINE DERIVATIVE
    • 氟代甲基吡咯烷衍生物
    • US20090012119A1
    • 2009-01-08
    • US11813950
    • 2006-01-20
    • Hisashi TakahasiRie MiyauchiMakoto Takemura
    • Hisashi TakahasiRie MiyauchiMakoto Takemura
    • A61K31/4709C07D401/02A61P3/04
    • C07D401/04
    • This invention relates to a compound represented by the following formula (1):[F.1] its salt or a hydrate thereof. R1 represents hydrogen atom, an optionally substituted alkyl group containing 1 to 6 carbon atoms, a cycloalkyl group containing 3 to 6 carbon atoms, or a substituted carbonyl group derived from an amino acid, a dipeptide, or a tripeptide; R2 represents hydrogen atom, an optionally substituted alkyl group containing 1 to 6 carbon atoms, or a cycloalkyl group containing 3 to 6 carbon atoms; R3 represents an alkyl group containing 1 to 6 carbon atoms or a halogen-substituted alkyl group containing 1 to 6 carbon atoms; R4 represents a cycloalkyl group containing 3 to 6 carbon atoms or a halogen-substituted cycloalkyl group containing 3 to 6 carbon atoms; R5 represents hydrogen atom, phenyl group, acetoxymethyl group, pivaloyloxymethyl group, ethoxycarbonyl group, choline group, dimethylaminoethyl group, 5-indanyl group, phthalidyl group, 5-alkyl-2-oxo-1,3-dioxol-4-ylmethyl group, 3-acetoxy-2-oxobutyl group, or a phenylalkyl group comprising an alkylene group containing 1 to 6 carbon atoms and phenyl group; X1 and X2 independently represent hydrogen atom or a halogen atom; and X represents hydrogen atom or a halogen atom. This compound exhibits broad and strong antibacterial activity to both Gram positive and Gram negative bacteria as well as high safety, and therefore, this compound is useful as a quinolone antibacterial drug, and a prophylactic and/or therapeutic drug for an infectious disease.
    • 本发明涉及由下式(1)表示的化合物:[F.1]其盐或其水合物。 R1表示氢原子,含有1-6个碳原子的任意取代的烷基,含有3-6个碳原子的环烷基或衍生自氨基酸,二肽或三肽的取代的羰基; R2表示氢原子,可以具有取代基的碳原子数为1〜6的烷基或碳原子数为3〜6的环烷基。 R3表示含有1至6个碳原子的烷基或含有1至6个碳原子的卤素取代的烷基; R 4表示碳原子数3〜6的环烷基或碳原子数3〜6的卤素取代环烷基。 R5表示氢原子,苯基,乙酰氧基甲基,新戊酰氧基甲基,乙氧基羰基,胆碱基,二甲基氨基乙基,5-二氢化茚基,苯酞基,5-烷基-2-氧代-1,3-二氧杂环戊烯-4-基甲基, 3-乙酰氧基-2-氧代丁基或含有1〜6个碳原子的亚烷基的苯基烷基和苯基; X1和X2独立地表示氢原子或卤原子; X表示氢原子或卤原子。 该化合物对革兰氏阳性和革兰氏阴性细菌具有广泛和强的抗菌活性以及高安全性,因此该化合物可用作喹诺酮抗菌药物,以及用于感染性疾病的预防和/或治疗药物。