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    • 95. 发明申请
    • APPARATUS AND METHOD FOR PROCESSING CELL CULTURE DATA
    • 用于处理细胞培养数据的装置和方法
    • US20120208227A1
    • 2012-08-16
    • US13395857
    • 2010-09-21
    • Christopher JohnsonMarina TaruninaYen ChooSimon ListerRobert Merrifield
    • Christopher JohnsonMarina TaruninaYen ChooSimon ListerRobert Merrifield
    • G06F19/00C12M1/34G01N21/17
    • G06F19/24
    • One embodiment of the invention provides a method of processing cell culture data. The data comprises results from a large number of samples, the results being obtained by performing multiple stages of cell culture in succession on each sample. Each stage represents a cell culture treatment having a particular set of conditions, such that each sample follows a protocol specified by the identity and order of the treatments applied to the cell culture. The method includes specifying a subset of the samples that yielded a desired cell culture outcome. The method further includes performing a computer-implemented analysis of the results from the samples in the subset to produce an ordering or grouping for the results. The ordering or grouping helps to identify one or more protocols that are effective for obtaining the desired cell culture outcome. The analysis for producing the ordering or grouping utilises information on similarities between different protocols.
    • 本发明的一个实施方案提供了处理细胞培养数据的方法。 数据包括大量样品的结果,结果是通过在每个样品上连续进行多个细胞培养阶段获得的。 每个阶段表示具有特定条件集合的细胞培养处理,使得每个样品遵循由应用于细胞培养物的处理的身份和顺序指定的方案。 该方法包括指定产生所需细胞培养结果的样品的子集。 该方法还包括对来自子集中的样本的结果进行计算机实现的分析,以产生用于结果的排序或分组。 排序或分组有助于识别对于获得所需细胞培养结果有效的一种或多种方案。 生产排序或分组的分析利用不同协议之间相似性的信息。
    • 98. 发明授权
    • Enterprise proposal management system
    • 企业提案管理系统
    • US07996441B2
    • 2011-08-09
    • US12366255
    • 2009-02-05
    • Christopher JohnsonMichael Branson
    • Christopher JohnsonMichael Branson
    • G06F7/06G06F17/30G06Q10/00
    • G06Q10/06G06Q10/0631G06Q10/06311G06Q10/101G06Q10/1053G06Q40/04Y10S707/99945Y10S707/99948
    • A system and method for managing an enterprise is provided. The system and method may be based on a layered architecture including a data center that may store all documents and data abstractions for an enterprise. One or more services may interact with an enterprise resource planning system and/or a customer relationship manager to facilitate interaction with the documents and data abstractions. A client access point of the system may include a graphical user interface that includes one or more enterprise management functions for managing the enterprise documents and/or data abstractions. The enterprise management functions may include a user proposal manager, an enterprise proposal manager, a proposal library, a content health manager, an archive library, a bid center, a contracts manager, a resume manager, a debriefing center and/or a projects manager. The enterprise management functions man re-engineer business processes and enable users to manage all aspects of an enterprise using a single unified interface.
    • 提供了一种用于管理企业的系统和方法。 系统和方法可以基于包括可以存储企业的所有文档和数据抽象的数据中心的分层架构。 一个或多个服务可以与企业资源规划系统和/或客户关系管理器进行交互,以促进与文档和数据抽象的交互。 系统的客户端接入点可以包括包括用于管理企业文档和/或数据抽象的一个或多个企业管理功能的图形用户界面。 企业管理功能可以包括用户提案管理器,企业提案管理器,提案库,内容健康管理器,归档库,出价中心,合同经理,简历管理器,汇报中心和/或项目经理 。 企业管理功能人员重新设计业务流程,使用户能够使用单一的统一接口来管理企业的各个方面。
    • 99. 发明申请
    • System And Method For Optimizing Simulation Of A Discrete Event Process Using Business System Data
    • 使用业务系统数据优化离散事件过程仿真的系统和方法
    • US20070288212A1
    • 2007-12-13
    • US11753868
    • 2007-05-25
    • Richard MessmerDan YangChristopher JohnsonBrian Dingman
    • Richard MessmerDan YangChristopher JohnsonBrian Dingman
    • G06G7/48
    • G06Q10/00G06Q10/06
    • The invention discloses simulation of a process of discrete events or tasks having a plurality of available resources associated therewith. A database stores a plurality of models, each including a plurality of one or more entity, task, and resource parameter, and dependencies and relationships. A model application communicates with the database and is configured to receive commands from a user, to retrieve one of the plurality of models and the corresponding plurality of one or more entity, task, and resource parameter in response to a user command, to receive input data corresponding to one or more entity, task, and resource parameter from a business database system, and to generate a simulation model based on the business database system and the input data. An optimizing application in communication with the model application and is configured to receive commands from a user, to select one or more entity, task, and resource parameter of the simulation model with respect to an objective function, to define bounds of the one or more entity, task, and resource parameter selected, to generate values for the objective function based on the one or more of the entity, task, and resource parameter selected, and to generate financial performance data based on the values generated for the objective function. A server performs a simulation of the process by processing the simulation model and generates an output data file containing output data representative thereof. The objective function comprises a combination of system financial performance measures (e.g., operational margin) and process performance measures (e.g., cycle time, throughput, utilization.
    • 本发明公开了具有与其相关联的多个可用资源的离散事件或任务的过程的模拟。 数据库存储多个模型,每个模型包括多个一个或多个实体,任务和资源参数以及依赖关系。 模型应用程序与数据库进行通信,并被配置为响应于用户命令接收来自用户的命令,以检索多个模型中的一个和相应的多个一个或多个实体,任务和资源参数,以接收输入 与业务数据库系统中的一个或多个实体,任务和资源参数对应的数据,以及基于业务数据库系统和输入数据生成仿真模型。 与模型应用通信的优化应用,并被配置为从用户接收命令,相对于目标函数选择仿真模型的一个或多个实体,任务和资源参数,以定义所述一个或多个 实体,任务和资源参数,基于所选择的实体,任务和资源参数中的一个或多个生成用于目标函数的值,并且基于为目标函数生成的值来生成财务性能数据。 服务器通过处理仿真模型来执行该过程的模拟,并生成包含其代表的输出数据的输出数据文件。 目标函数包括系统财务绩效测量(例如,操作余量)和过程绩效测度(例如,周期时间,吞吐量,利用率)的组合。