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    • 94. 发明申请
    • Methods for the treatment and prevention of inflammatory diseases
    • 治疗和预防炎性疾病的方法
    • US20060270630A1
    • 2006-11-30
    • US11437988
    • 2006-05-19
    • Charles SmithKevin FrenchLynn Maines
    • Charles SmithKevin FrenchLynn Maines
    • A61K31/685
    • A61K31/685
    • The invention includes processes mainly for the treatment of a inflammatory diseases, such as inflammatory bowel disease, arthritis, atherosclerosis, asthma, allergy, inflammatory kidney disease, circulatory shock, multiple sclerosis, chronic obstructive pulmonary disease, skin inflammation, periodontal disease, psoriasis and T cell-mediated diseases of immunity, including allergic encephalomyelitis, allergic neuritis, transplant allograft rejection, graft versus host disease, myocarditis, thyroiditis, nephritis, systemic lupus erthematosus, and insulin-dependent diabetes mellitus. The processes involve treating a patient with a pharmaceutical composition containing an active ingredient that inhibits the activity of sphingosine kinase.
    • 本发明包括主要用于治疗诸如炎性肠病,关节炎,动脉粥样硬化,哮喘,变态反应,炎症性肾病,循环性休克,多发性硬化,慢性阻塞性肺疾病,皮肤炎症,牙周病,牛皮癣和炎症性疾病 T细胞介导的免疫疾病,包括过敏性脑脊髓炎,过敏性神经炎,移植异种移植排斥反应,移植物抗宿主病,心肌炎,甲状腺炎,肾炎,系统性红斑狼疮和胰岛素依赖性糖尿病。 该方法包括用含有抑制鞘氨醇激酶活性的活性成分的药物组合物治疗患者。
    • 96. 发明申请
    • Removable electronic storage crushing device
    • 可移动电子储存破碎装置
    • US20060219829A1
    • 2006-10-05
    • US11390943
    • 2006-03-28
    • Charles Smith
    • Charles Smith
    • A47J17/00
    • B02C1/005B02C1/14G11B23/505
    • A removable electronic storage crushing device having a housing, a cylinder, a rod, a crushing head, and a receiving plate. The cylinder is threadedly received in the house and the rod an end of the rod is threadedly received by the crushing head. A source of power is operatively connected to the cylinder, which is operatively connected to the rod. Applying power or force to the cylinder biases the rod and the crushing head in a direction generally parallel to the housing's central axis toward a receiving plate, which defines a bore configured to receive at least part of the crushing head. When the crushing head comes into contact with a removable electronic storage device situated on top of the receiving plate, the force applied by the crushing head crushes the removable electronic storage device and any platters therein.
    • 一种具有壳体,气缸,杆,破碎头和接收板的可移除电子存储破碎装置。 圆筒被螺纹地容纳在房屋中,杆的端部被破碎头螺纹地接收。 动力源可操作地连接到可操作地连接到杆的气缸。 将力或力施加到气缸上将杆和破碎头沿着大致平行于壳体的中心轴线的方向朝向容纳板偏压,该接收板限定构造成容纳至少部分破碎头的孔。 当破碎头与位于接收板顶部的可移动电子存储装置接触时,由破碎头施加的力将可拆卸的电子存储装置和任何盘片破碎。
    • 99. 发明申请
    • Method and system for knowledge assessment and learning
    • 知识评估和学习的方法和系统
    • US20050227215A1
    • 2005-10-13
    • US10398625
    • 2001-10-04
    • James BrunoCharles SmithArthur BlankLen SchiedelBob Serling
    • James BrunoCharles SmithArthur BlankLen SchiedelBob Serling
    • G09B7/00G09B7/02
    • G09B7/00G09B7/02
    • A method and system for knowledge assessment and learning for assessing the true knowledge of a human subject. The invention incorporates non-one dimensional testing techniques to obtain the subject's knowledge and confidence level associated with the knowledge. The invention produces an assessment or test prolific, which includes formative and summative evaluation. The profile is correlated to database of learning materials and presented to the subject for review and/or reeducation of the substantive response thereby ensuring the subject's acquisition of the true knowledge or accurate information. The invention accommodates various test queries without regard to the specific nature of the subject matter on which the test subject is queried. The present invention is adaptable for use in a microprocessor-based stand alone computers, as well as for individual use or distributed in a client-server environment of a communication network. When so adapted, the system incorporates a plurality of user-interfaces and Web browser dialog controls, which are supported by system for the user to input the queries, administer the assessment, provide feedback to the system use and/or the test subject and to provide learning materials according to the assessment profile.
    • 用于评估人类主体真实知识的知识评估和学习的方法和系统。 本发明包含非一维测试技术以获得与知识相关的受试者的知识和置信水平。 本发明产生了多种评估或测试,包括形成性和总结性评估。 该资料与学习材料的数据库相关,并提交给该主题以进行实质性回应的审查和/或重新教育,从而确保受试者获得真实知识或准确的信息。 本发明容纳各种测试查询,而不考虑查询测试对象的主题的具体性质。 本发明适用于基于微处理器的独立计算机,以及用于个人使用或分布在通信网络的客户端 - 服务器环境中。 当这样进行调整时,该系统包含多个用户界面和Web浏览器对话控件,这些控件由系统支持以供用户输入查询,管理评估,向系统使用和/或测试对象提供反馈,以及 根据评估资料提供学习资料。