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91. 发明授权

US5840749A N-hydroxy-dibenz �b,e!oxepinalkylamines, N-hydroxy-dibenz �b,e!oxepinalkanoic acid amides and related heterocyclic analogues 失效
标题翻译： N-羟基 - 二苯并[b，e]氧基烷基胺，N-羟基 - 二苯并[b，e]氧代庚酸酰胺和相关杂环类似物
公开(公告)号：US5840749A
公开(公告)日：1998-11-24
申请号：US207464
申请日：1994-03-08
申请人： Richard C. Allen , Grover C. Helsley , R. Richard L. Hamer , Brian S. Freed , John I. White , Lawrence L. Martin
发明人： Richard C. Allen , Grover C. Helsley , R. Richard L. Hamer , Brian S. Freed , John I. White , Lawrence L. Martin
IPC分类号： C07D313/12 , C07D495/04 , A61K31/335
CPC分类号： C07D495/04 , C07D313/12
摘要： This invention relates to N-hydroxy-dibenz�b,e!oxepinalkylamines, N-hydroxy-dibenz�b,e!oxepinalkanoic acid amides and related heterocyclic analogues of the formula ##STR1## where X together with the carbon atoms to which it is attached forms a benzene or thiophene ring; W and Z are independently hydrogen, halogen, loweralkyl, or trifluoromethyl; R.sup.1 is hydrogen, arylloweralkyl, loweralkoxycarbonyl, loweralkylcarbonyl, arylcarbonyl or arylloweralkylcarbonyl; R.sup.2 is loweralkyl, cycloalkyl, arylloweralkyl, loweralkoxycarbonyl, loweralkylcarbonyl, arylcarbonyl or arylloweralkylcarbonyl; m is 0 or 1 and n is an integer of 0 to 4 or the pharmaceutically acceptable salts thereof. The compounds of this invention are useful as analgesics and topical antiinflammatory agents for the treatment of various dermatoses and agents for the treatment of conditions where accumulation of cyclooxygenase and/or lipoxygenase metabolites is a causative factor.
摘要翻译：本发明涉及N-羟基 - 二苯并[b，e]氧基烷基胺，N-羟基 - 二苯并[b，e]氧代庚酸酰胺及其相关杂环类似物，其中X与它们的碳原子一起附着形成苯或噻吩环; W和Z独立地是氢，卤素，低级烷基或三氟甲基; R1是氢，芳基低级烷基，低级烷氧基羰基，低级烷基羰基，芳基羰基或芳基低级烷基羰基; R2是低级烷基，环烷基，芳基低级烷基，低级烷氧基羰基，低级烷基羰基，芳基羰基或芳基低级烷基羰基; m为0或1，n为0〜4的整数或其药学上可接受的盐。本发明的化合物可用作用于治疗各种皮肤病的止痛剂和局部抗炎剂和用于治疗环氧合酶和/或脂氧合酶代谢物积累是致病因素的病症的药剂。

92. 发明授权

US5610455A Electret containing syndiotactic vinyl aromatic polymer 失效
标题翻译：含有间同立构乙烯基芳族聚合物的驻极体
公开(公告)号：US5610455A
公开(公告)日：1997-03-11
申请号：US496356
申请日：1995-06-29
申请人： Richard C. Allen , Anthony F. Flannery , Charles R. Kleissler , David B. Redmond
发明人： Richard C. Allen , Anthony F. Flannery , Charles R. Kleissler , David B. Redmond
IPC分类号： C08J5/18 , B29C55/02 , B29K25/00 , B29L7/00 , C08F12/06 , C08L25/00 , H01B3/30 , G11C13/02
CPC分类号： C08F12/06 , Y10S55/39 , Y10T428/24942
摘要： Electrets are disclosed comprising syndiotactic vinyl aromatic polymer, for example syndiotactic polystyrene. These electrets have good charge retention at elevated temperature.
摘要翻译：披露了间同立构乙烯基芳族聚合物例如间同立构聚苯乙烯的驻极体。这些驻极体在高温下具有良好的电荷保持性。

93. 发明授权

US5542840A Burner for combusting gas and/or liquid fuel with low NO.sub.x production 失效
标题翻译：用于燃烧低NOx产生气体和/或液体燃料的燃烧器
公开(公告)号：US5542840A
公开(公告)日：1996-08-06
申请号：US538621
申请日：1995-10-04
申请人： David J. Surbey , James L. Smith , Richard C. Allen , Alan D. Witwer
发明人： David J. Surbey , James L. Smith , Richard C. Allen , Alan D. Witwer
IPC分类号： F23C9/00 , F23D14/22 , F23M5/02 , F23M3/00
CPC分类号： F23C9/006 , F23D14/22 , F23M5/025 , F23C2201/30 , F23C2202/20 , F23C2900/09002
摘要： A burner for combusting gas and/or liquid fuel and air in an enclosure includes a burner block of non-combustible material, such as ceramic material, having a central opening therethrough communicating with a combustion zone. The burner block has a plurality of spaced apart recirculation gas passageways paralleled to and spaced from the central opening, each of the recirculation gas passageways having an injection passageway communicating with the block member central opening. Fuel, which may be liquid and/or gas, is injected into said burner block central opening. Venturi action causes furnace gas to be drawn from the cool fringes of the combustion zone through the recirculation gas passageways for passage back into the central opening wherein air and fuel are thoroughly mixed and cooled for combustion within the enclosure. This recirculation system serves to reduce the temperature and oxygen content of the local combustion process to thereby reduce NO.sub.x production. An annular flame director ring positioned within the burner block central opening adjacent to and below the injection passageways augments the Venturi action to increase flow through the recirculation passageways.
摘要翻译：用于在外壳中燃烧气体和/或液体燃料和空气的燃烧器包括不燃性材料（例如陶瓷材料）的燃烧器组件，其具有与燃烧区域连通的中心开口。燃烧器块具有与中心开口平行并间隔开的多个间隔开的再循环气体通道，每个再循环气体通道具有与块构件中心开口连通的注入通道。可以将液体和/或气体的燃料注入燃烧器中心开口。文丘里作用导致炉气从燃烧区的冷条纹通过再循环气体通道被抽出，以通过回到中心开口，其中空气和燃料被充分混合并冷却以在外壳内燃烧。该再循环系统用于降低局部燃烧过程的温度和氧含量，从而减少NOx产生。定位在燃烧器中心开口内的环形火焰导向器环邻近喷射通道和其下方，增加文丘里作用以增加通过再循环通道的流动。

94. 发明授权

US5427842A Tear resistant multilayer films and articles incorporating such films 失效
标题翻译：含有这种膜的抗撕裂多层膜和制品
公开(公告)号：US5427842A
公开(公告)日：1995-06-27
申请号：US250645
申请日：1994-05-27
申请人： Ralph H. Bland , James M. Jonza , James D. Smith , Richard C. Allen , Jeffrey F. Bradley , Kenneth B. Smith , Bruce D. Stambaugh
发明人： Ralph H. Bland , James M. Jonza , James D. Smith , Richard C. Allen , Jeffrey F. Bradley , Kenneth B. Smith , Bruce D. Stambaugh
IPC分类号： B32B7/02 , B32B17/10 , B32B27/36 , B32B27/08 , B32B7/12
CPC分类号： B32B17/10174 , B32B17/10018 , B32B27/36 , B32B7/02 , Y10S428/91 , Y10S428/911 , Y10T428/1443 , Y10T428/1448 , Y10T428/24942 , Y10T428/2495 , Y10T428/24967 , Y10T428/24975 , Y10T428/2848 , Y10T428/31554 , Y10T428/31562 , Y10T428/31565 , Y10T428/31573 , Y10T428/31616 , Y10T428/31623 , Y10T428/31645 , Y10T428/31728 , Y10T428/31732 , Y10T428/31736 , Y10T428/31743 , Y10T428/31757 , Y10T428/31786 , Y10T428/31797 , Y10T428/31909
摘要： A tear resistant film comprises more than five layers situated one on the other in a parallel array. The layers are individually selected from a stiff polyester or copolyester, a ductile polymeric material, and optionally, an intermediate material. The stiff polyester or copolyester is oriented in at least one direction. Tear resistance may be measured in a Graves area test and reflects the ability of the film to absorb energy. The films of the invention are useful in many articles including security control laminates for glazing members.
摘要翻译：抗撕裂膜包含多于五层的平行排列的另一层。这些层分别选自刚性聚酯或共聚酯，延性聚合物材料和任选的中间材料。刚性聚酯或共聚酯在至少一个方向上取向。抗撕裂性可以在格雷夫斯（Graves）区域测试中测量，并反映了薄膜吸收能量的能力。本发明的薄膜在许多制品中是有用的，其中包括用于玻璃制品的安全控制层压板。

95. 发明授权

US5378856A Transmission cable having a nonhalogenated jacket formulation 失效
标题翻译：传输电缆具有非卤素护套配方
公开(公告)号：US5378856A
公开(公告)日：1995-01-03
申请号：US989175
申请日：1992-12-11
申请人： Richard C. Allen
发明人： Richard C. Allen
IPC分类号： G02B6/44 , H01B7/295 , H01B11/02 , H01B7/34
CPC分类号： G02B6/4436 , H01B11/02 , H01B7/295 , Y10S428/921
摘要： A transmission cable having a nonhalogenated jacket and a nonhalogenated composition for use as a transmission cable jacket. The jacket is prepared from a nonhalogenated polyolefin based formulation having flame retardant, low corrosivity, low toxicity and low smoke characteristics. The jacket material insulates a core transmission medium such as a metallic conductor or optical fiber. The jacket is extruded about the core or insulator during manufacture. The inventive cable has a jacket formed of nonhalogenated polyethylene and nonhalogenated ethylene vinyl acetate and provides a combination of desired mechanical characteristics, improved performance and manufacturing features while eliminating undesirable corrosive products released during a fire.
摘要翻译：一种具有非卤素护套的传输电缆和用作传输电缆护套的非卤化组合物。夹套由具有阻燃性，低腐蚀性，低毒性和低烟特性的非卤代聚烯烃基配方制备。护套材料将核心传输介质如金属导体或光纤绝缘。夹套在制造过程中围绕芯或绝缘体挤出。本发明的电缆具有由非卤代聚乙烯和非卤代乙烯 - 乙酸乙烯酯形成的护套，并提供期望的机械特性，改进的性能和制造特征的组合，同时消除在火灾期间释放的不期望的腐蚀性产品。

96. 发明授权

US5216017A Pyrrolo[2,3-b]indole-ketones and analogs 失效
标题翻译：吡咯并[2,3-b]吲哚酮和类似物
公开(公告)号：US5216017A
公开(公告)日：1993-06-01
申请号：US765780
申请日：1991-09-26
申请人： Richard C. Allen , Denise M. Flanagan
发明人： Richard C. Allen , Denise M. Flanagan
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： This invention relates to pyrrolo[2,3-b]indole ketones of the formula ##STR1## where R.sub.1 is loweralkyl, aryl or arylloweralkyl; R.sub.2 is hydrogen, halogen or loweralkyl; R.sub.3 is hydrogen or loweralkyl; R.sub.4 is loweralkyl or arylloweralkyl; R.sub.5 is hydrogen, loweralkyl, loweralkenyl, loweralkynyl, arylloweralkyl, formyl, loweralkylcarbonyl, arylloweralkylcarbonyl or loweralkoxycarbonyl; Y is hydrogen, loweralkyl or loweralkoxy; the pharmaceutically acceptable addition salts thereof, and where applicable, the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention are useful in the treatment of memory impairment characterized by a cholinergic deficit such as that associated with electroshock-induced amnesia and Alzheimer's disease and other senile dementia.
摘要翻译：本发明涉及式（Ia）的吡咯并[2,3-b]吲哚酮，其中R 1是低级烷基，芳基或芳基低级烷基; R2是氢，卤素或低级烷基; R3是氢或低级烷基; R4是低级烷基或芳基低级烷基; R5是氢，低级烷基，低级烯基，低级炔基，芳基低级烷基，甲酰基，低级烷基羰基，芳基低级烷基羰基或低级烷氧基羰基。 Y是氢，低级烷基或低级烷氧基; 其药学上可接受的加成盐，以及适用的几何和旋光异构体及其外消旋混合物。本发明的化合物可用于治疗特征为胆碱能缺乏的记忆障碍，例如与电击诱发的遗忘症和阿尔茨海默病和其他老年痴呆相关的记忆障碍。

97. 发明授权

US5145965A 2,6-methanopyrrolo-3-benzazocines 失效
标题翻译： 2,6-甲基吡咯-3-苯并吖嗪
公开(公告)号：US5145965A
公开(公告)日：1992-09-08
申请号：US666394
申请日：1991-03-11
申请人： Richard C. Allen , David G. Wettlaufer
发明人： Richard C. Allen , David G. Wettlaufer
IPC分类号： C07D221/26 , C07D471/08
CPC分类号： C07D471/08 , C07D221/26
摘要： Novel 2,6-methanopyrrolo-3-benzazocines, intermediates, processes for the preparation thereof, and methods for alleviating pain utilizing compounds or compositions thereof are disclosed.
摘要翻译：公开了新颖的2,6-甲基吡咯并-3-苯并吖嗪，中间体，其制备方法，以及利用化合物或其组合物减轻疼痛的方法。

98. 发明授权

US5109011A P-acylaminophenoxycarbamates and derivatives 失效
标题翻译：对氨基苯甲酸甲酯和衍生物
公开(公告)号：US5109011A
公开(公告)日：1992-04-28
申请号：US566291
申请日：1990-07-30
申请人： Richard C. Allen , Raymond W. Kosley, Jr. , Bettina Spahl
发明人： Richard C. Allen , Raymond W. Kosley, Jr. , Bettina Spahl
IPC分类号： A61K31/215 , A61K31/27 , A61K31/415 , A61K31/44 , A61K31/4409 , A61P25/04 , C07C271/40 , C07C271/42 , C07C271/44 , C07D213/54 , C07D213/79 , C07D233/60 , C07D521/00
CPC分类号： C07D231/12 , C07C271/40 , C07C271/44 , C07D213/54 , C07D233/56 , C07D249/08
摘要： This invention relates to p-acylaminophenoxycarbamates having the formula ##STR1## where R.sub.1 and R.sub.2 are each independently hydrogen, loweralkyl, aryl and arylloweralkyl; R.sub.3 is hydrogen, loweralkyl, aryllowerallkyl; R.sub.4 is hydrogen, loweralkyl, formyl, alkylcarbonyl, arylloweralkyl, phenylcarbonyl, arylloweralkylcarbonyl, substituted phenylcarbonyl, pyridylcarbonyl, and substituted pyridylcarbonyl with the proviso that if R.sub.4 contains a carbonyl group directly attached to the oxygen of the N-O moiety, R.sub.3 cannot by hydrogen; or R.sub.3 and R.sub.4 taken together form a heterocyclic ring selected from the group consisting of imidazole or loweralkylimidazole; X is hydrogen, halogen, hydroxy, loweralkyl, loweralkoxy, nitro, amino or trifluoromethyl; and p is an integer selected from 0 and 1; the pharmaceutically acceptable acid addition salts thereof, and where applicable, the geometric and stereoisomers and racemic mixtures thereof. The compounds of this invention display utility as analgesics.

99. 发明授权

US5091541A Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds 失效
标题翻译：六氢吡咯（2,3-B）吲哚氨基甲酸酯，脲，酰胺和相关化合物
公开(公告)号：US5091541A
公开(公告)日：1992-02-25
申请号：US602559
申请日：1990-10-24
申请人： Gerard J. O'Malley , Richard C. Allen , John I. White
发明人： Gerard J. O'Malley , Richard C. Allen , John I. White
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： There are disclosed various compounds of the formula below, ##STR1## where X is O, S, NH, N-loweralkyl, or N-arylloweralkyl;Y is hydrogen, fluorine, chlorine, bromine, nitro, loweralkyl, loweralkoxy, or triloweralkylsilyl;R.sub.1 is loweralkyl, halogen-substituted loweralkyl, aryl, arylloweralkyl, cycloalkyl, heteroaryl or heteroarylloweralkyl;R.sub.2 is hydrogen, loweralkyl or arylloweralkyl;R.sub.3 is loweralkyl or arylloweralkyl;R.sub.4 is hydrogen, loweralkyl, loweralkenyl, loweralkynyl, arylloweralkyl, formyl, loweralkylcarbonyl, arylloweralkylcarbonyl or loweralkoxycarbonyl;R.sub.5 is hydrogen or loweralkyl; andm is 0 or 1, with the proviso that when m is O, R.sub.1 may also be hydrogen.which compounds are useful for alleviating various memory dysfunctions characterized by a cholinergic deficit such as Alzheimer's disease.
摘要翻译：公开了下式的各种化合物，其中X是O，S，NH，N-低级烷基或N-芳基低级烷基; Y是氢，氟，氯，溴，硝基，低级烷基，低级烷氧基或三氟烷基甲硅烷基; R 1是低级烷基，卤素取代的低级烷基，芳基，芳基低级烷基，环烷基，杂芳基或杂芳基低级烷基; R2是氢，低级烷基或芳基低级烷基; R3是低级烷基或芳基低级烷基; R4是氢，低级烷基，低级烯基，低级炔基，芳基低级烷基，甲酰基，低级烷基羰基，芳基低级烷基羰基或低级烷氧基羰基。 R5是氢或低级烷基; 且m为0或1，条件是当m为O时，R 1也可为氢。哪些化合物可用于缓解以胆碱能缺乏为特征的各种记忆功能障碍如阿尔茨海默氏病。

100. 发明授权

US4963685A Intermediates for the preparation of tetrahydroisoquino[2,1-c][1,3]benzodiazepines 失效
标题翻译：用于制备四氢异喹啉[2,1-c] [1,3]苯并二氮杂卓的中间体
公开(公告)号：US4963685A
公开(公告)日：1990-10-16
申请号：US454490
申请日：1989-12-21
申请人： Lawrence L. Martin , Richard C. Allen
发明人： Lawrence L. Martin , Richard C. Allen
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： Novel Tetrahydroisoquino[2,1-c][1,3]benzodiazepines are disclosed having the formula ##STR1## where X and Y are each independently hydrogen, halogen, loweralkyl, loweralkoxy or --CF.sub.3, and R is hydrogen or loweralkyl, and the pharmaceutically acceptable acid addition salts thereof and where applicable the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention display utility in enhancing memory.
摘要翻译：公开了新的四氢异喹啉[2,1-c] [1,3]苯并二氮杂，其具有式“IMAGE”，其中X和Y各自独立地为氢，卤素，低级烷基，低级烷氧基或-CF 3，R为氢或低级烷基，其药学上可接受的酸加成盐，以及适用的几何和光学异构体及其外消旋混合物。本发明的化合物显示用于增强记忆力的效用。

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