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    • 93. 发明申请
    • CLOSED-LOOP THERAPY ADJUSTMENT
    • 闭环治疗调整
    • US20110238136A1
    • 2011-09-29
    • US13154303
    • 2011-06-06
    • Duane BourgetKeith A. Miesel
    • Duane BourgetKeith A. Miesel
    • A61N1/36
    • A61N1/37252A61N1/36021A61N1/36071A61N1/37247
    • Techniques for detecting a value of a sensed patient parameter, and automatically delivering therapy to a patient according to therapy information previously associated with the detected value, are described. In exemplary embodiments, a medical device receives a therapy adjustment from the patient. In response to the adjustment, the medical device associates a sensed value of a patient parameter with therapy information determined based on the adjustment. Whenever the parameter value is subsequently detected, the medical device delivers therapy according to the associated therapy information. In this manner, the medical device may “learn” to automatically adjust therapy in the manner desired by the patient as the sensed parameter of the patient changes. Exemplary patient parameters that may be sensed for performance of the described techniques include posture, activity, heart rate, electromyography (EMG), an electroencephalogram (EEG), an electrocardiogram (ECG), temperature, respiration rate, and pH.
    • 描述了用于检测感测到的患者参数的值并根据先前与检测值相关联的治疗信息自动地向患者递送治疗的技术。 在示例性实施例中,医疗设备从患者接收治疗调节。 响应于调整,医疗设备将感测到的患者参数值与基于调整确定的治疗信息相关联。 每当随后检测到参数值时,医疗装置根据相关联的治疗信息递送治疗。 以这种方式,当患者的感测参数改变时,医疗设备可以“学习”以患者期望的方式自动调整治疗。 可以感测用于执行所述技术的示例性患者参数包括姿势,活动,心率,肌电图(EMG),脑电图(EEG),心电图(ECG),温度,呼吸速率和pH。
    • 94. 发明授权
    • Pressure sensing in implantable medical devices
    • 可植入医疗器械中的压力感测
    • US07955319B2
    • 2011-06-07
    • US11778400
    • 2007-07-16
    • Keith A. Miesel
    • Keith A. Miesel
    • A61M5/142
    • A61M5/14276A61M5/16854A61M2205/3355A61M2205/3523
    • An implantable medical device for delivering a therapeutic substance to a delivery site in a patient. A reservoir holds a supply of the fluid therapeutic substance. A catheter has a proximal end, a delivery region and a lumen extending from the proximal end to the delivery region. The proximal end of the catheter is operatively coupled to the reservoir. The delivery region of the catheter is adapted to be placed proximate the delivery site in the patient. The therapeutic substance is adapted to be delivered through the lumen to the patient. A sensing device is operatively coupled with the lumen of the catheter being capable of detecting a pressure of the therapeutic substance in the lumen. A controller is operatively coupled to the sensing device, the controller being capable of taking an action in response to the pressure in the lumen.
    • 一种用于将治疗物质输送到患者的输送部位的可植入医疗装置。 储存器容纳流体治疗物质的供应。 导管具有近端,输送区域和从近端延伸到输送区域的内腔。 导管的近端可操作地联接到储存器。 导管的输送区域适于放置在患者体内的输送部位附近。 治疗物质适于通过内腔输送给患者。 感测装置与导管的内腔可操作地耦合,能够检测内腔中的治疗物质的压力。 控制器可操作地耦合到感测装置,所述控制器能够响应于内腔中的压力而采取动作。
    • 100. 发明授权
    • Tube sensor for penile tumescence
    • 管传感器用于阴茎勃起
    • US07623923B2
    • 2009-11-24
    • US11117054
    • 2005-04-28
    • Martin T. GerberKeith A. Miesel
    • Martin T. GerberKeith A. Miesel
    • A61N1/08A61F5/41
    • A61N1/36007A61B5/0031A61B5/4393
    • The disclosure describes a tube pressure sensor to measure penile tumescence which may be used in a therapeutic penile tumescence control system. The system senses penile pressure and sends the information to a stimulator that is capable of stimulation therapy to control an erectile state, thus treating sexual dysfunction or, more specifically, erectile dysfunction. Measuring penile tumescence pressure is accomplished through the use of a tube placed within the urethra of the penis and attached to a module implanted within the bladder. Pressure on the tube generates an electrical signal that is sent wirelessly to an implanted stimulator connected to a lead positioned near pelvic floor nerves that stimulate erections. An external device may be used to wirelessly send information to the implanted stimulator to start or stop stimulation in order for the patient to conduct normal sexual activity. In addition, pressure information and stimulation information may be recorded and reviewed by a physician for continued therapy monitoring.
    • 本公开内容描述了用于测量阴茎肿胀的管压力传感器,其可用于治疗性阴茎肿胀控制系统。 该系统感测阴茎压力并将信息发送到能够刺激治疗以控制勃起状态的刺激器,从而治疗性功能障碍,或更具体地说是勃起功能障碍。 测量阴茎肿胀压力是通过使用放置在阴茎尿道内的管并附着在植入膀胱内的模块来实现的。 管上的压力产生电信号,该电信号被无线地发送到植入的刺激器,其连接到位于骨盆底部神经附近的引导件,该刺激器刺激勃起。 可以使用外部设备来将信息无线地发送到植入的刺激器以开始或停止刺激,以使患者进行正常的性活动。 此外,医师可以记录和审查压力信息和刺激信息以进行持续的治疗监测。