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    • 2. 发明授权
    • Ionophoretic device for transdermal administration of medicaments, and
disposable assembly forming part of such device
    • 用于透皮给药的离子电泳装置,以及形成这种装置的一部分的一次性组装
    • US5983132A
    • 1999-11-09
    • US836308
    • 1997-05-12
    • Philippe MillotEric TeillaudMichel Lamoise
    • Philippe MillotEric TeillaudMichel Lamoise
    • A61N1/30A61N1/00
    • A61N1/044A61N1/303A61N1/0444
    • The device comprises a reservoir (3) containing an active principle in ionized form, first (1) and second (2) electrodes in contact with a face of the reservoir (3) and the skin (6) of the patient, respectively, the other face of the reservoir being applied to the skin (6) of the patient and means (5) for circulating selectively an electric current between said electrodes in order to help the passage of a flow of active principle under the patient's skin. The device further comprises a) a control grid (11) arranged on the face of the reservoir (3) which is intended to be applied to the skin (6) of the patient and b) control means (10), (9), (13) for cutting off the assistance current during a predetermined period of time and to circulate a reverse current between the grid (11) and the first electrode (1) which is intended to cancel substantially the passive flow of ions of the active principle which would otherwise pass under the patient's skin.
    • PCT No.PCT / FR95 / 01509 Sec。 371日期:1997年5月12日 102(e)日期1997年5月12日PCT提交1995年11月16日PCT公布。 WO96 / 14896 PCT公开号 日期1996年5月23日该装置包括容纳离子化形式的活性成分的储存器(3),与储存器(3)的表面和患者皮肤(6)接触的第一(1)和第二(2)电极 分别将储存器的另一面施加到患者的皮肤(6),以及用于选择性地在所述电极之间循环电流的装置(5),以帮助活动原理流通过患者皮肤 。 该装置还包括:a)设置在储存器(3)的面上的控制栅格(11),该控制栅格旨在施加到患者的皮肤(6),以及b)控制装置(10),(9), (13),用于在预定时间段内切断辅助电流,并且使网格(11)和第一电极(1)之间的反向电流循环,该逆电流旨在基本上抵消有源原理的被动流离子 否则会经过病人的皮肤。
    • 5. 发明申请
    • INTERFACE PRESSURE MEASUREMENT SYSTEM
    • 接口压力测量系统
    • US20110319787A1
    • 2011-12-29
    • US13143681
    • 2010-01-13
    • Michel LamoiseSerge LecomteJulien Steinbrunn
    • Michel LamoiseSerge LecomteJulien Steinbrunn
    • A61B5/01A61B5/00
    • A61B5/103A61B5/445A61B5/6833A61B2562/0247A61B2562/0261
    • The subject matter of the present invention is a system for measuring interface pressure exerted on the skin, that is in particular of use in compression therapy, characterized in that it comprises:—a supporting member bearing sensors, including at least two pressure sensors spaced out on the supporting member in order to make it possible to measure the pressure exerted at two predetermined positions;—an electronic system connected to the sensors and capable of acquiring the values simultaneously measured by these sensors; and in that each pressure sensor comprises a transducer element, which is preferably substantially flat, said transducer element having a surface intended to come into contact with the skin in the operating position, either directly or by means of a layer of a material covering said surface of the transducer, the elastic modulus of compression of said transducer or of said intermediate layer, measured at the surface intended to come into contact with the skin, being between 30 and 500 kPa, preferably between 80 and 400 kPa and more preferably between 200 and 400 kPa. Use: compression therapy.
    • 本发明的主题是用于测量施加在皮肤上的界面压力的系统,特别是在压缩治疗中使用的系统,其特征在于,其包括:支撑构件轴承传感器,包括至少两个间隔开的压力传感器 在支撑构件上,以便能够测量施加在两个预定位置的压力; - 连接到传感器的电子系统,并能够获取由这些传感器同时测量的值; 并且每个压力传感器包括优选地基本上平坦的换能器元件,所述换能器元件具有旨在在操作位置与皮肤接触的表面,直接地或通过覆盖所述表面的材料层 的传感器,在与皮肤接触的表面处测量的所述换能器或所述中间层的弹性模量为30-500kPa,优选为80-400kPa,更优选在200和 400 kPa。 用途:压缩治疗。
    • 6. 发明授权
    • Interface pressure measurement system
    • 接口压力测量系统
    • US08894590B2
    • 2014-11-25
    • US13143681
    • 2010-01-13
    • Michel LamoiseSerge LecomteJulien Steinbrunn
    • Michel LamoiseSerge LecomteJulien Steinbrunn
    • A61B5/03A61B5/117A61B5/103A61B5/00
    • A61B5/103A61B5/445A61B5/6833A61B2562/0247A61B2562/0261
    • The subject matter of the present invention is a system for measuring interface pressure exerted on the skin, that is in particular of use in compression therapy, characterized in that it comprises: —a supporting member bearing sensors, including at least two pressure sensors spaced out on the supporting member in order to make it possible to measure the pressure exerted at two predetermined positions; —an electronic system connected to the sensors and capable of acquiring the values simultaneously measured by these sensors; and in that each pressure sensor comprises a transducer element, which is preferably substantially flat, said transducer element having a surface intended to come into contact with the skin in the operating position, either directly or by means of a layer of a material covering said surface of the transducer, the elastic modulus of compression of said transducer or of said intermediate layer, measured at the surface intended to come into contact with the skin, being between 30 and 500 kPa, preferably between 80 and 400 kPa and more preferably between 200 and 400 kPa. Use: compression therapy.
    • 本发明的主题是用于测量施加在皮肤上的界面压力的系统,特别是在压缩治疗中使用的系统,其特征在于,其包括:支撑构件轴承传感器,包括至少两个间隔开的压力传感器 在支撑构件上,以便可以测量施加在两个预定位置的压力; - 连接到传感器的电子系统,并能够获取由这些传感器同时测量的值; 并且每个压力传感器包括优选地基本上平坦的换能器元件,所述换能器元件具有旨在在操作位置与皮肤接触的表面,直接地或通过覆盖所述表面的材料层 的换能器,在与皮肤接触的表面处测量的所述换能器或所述中间层的弹性模量为30-500kPa,优选为80-400kPa,更优选在200和 400 kPa。 用途:压缩治疗。