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1. 发明授权

US6102179A Device for transmission of one-way torque 失效
标题翻译：用于传递单向力矩的装置
公开(公告)号：US6102179A
公开(公告)日：2000-08-15
申请号：US850439
申请日：1997-05-05
申请人： Peter D. Hodson , Stephen J. Howgill , Anthony C. L. Wass
发明人： Peter D. Hodson , Stephen J. Howgill , Anthony C. L. Wass
IPC分类号： A61M15/00 , F16D41/18 , F16D41/12
CPC分类号： F16D41/18
摘要： A device for the transmission of one-way torque comprising an outer annular member having a plurality of radially inwardly projecting teeth each comprising a driving surface and a cam surface, and a shaft concentrically mounted with respect to the outer annular member and comprising a plurality of drive elements each having a driving surface and a cam surface. Rotation of the shaft or outer annular member in its driving direction causes engagement of a driving surface of at least one drive element with a driving surface of at least one tooth thereby resulting in joint rotation of the shaft and outer annular member. Rotation of the shaft or outer annular member in its non-driving direction causes engagement of the cam surface of at least one drive element with the cam surface of at least one tooth resulting in additional relative movement, substantially radially, between the drive element and tooth, thereby preventing rotational movement being transmitted between the shaft and the outer annular member.
摘要翻译：一种用于单向扭矩传递的装置，包括具有多个径向向内突出的齿的外环形构件，每个径向向内突出的齿各自包括驱动表面和凸轮表面，以及相对于外环形构件同心安装的轴，驱动元件各自具有驱动表面和凸轮表面。轴或外环形构件沿其驱动方向的旋转使得至少一个驱动元件的驱动表面与至少一个齿的驱动表面接合，从而导致轴和外环形构件的联合旋转。轴或外环形构件在其非驱动方向上的旋转导致至少一个驱动元件的凸轮表面与至少一个齿的凸轮表面的接合，从而在驱动元件和齿之间基本上径向地进一步相对移动从而防止旋转运动在轴和外环形构件之间传递。

2. 发明授权

US06460537B1 Breath-actuated aerosol dispensers 失效
标题翻译：呼吸式气雾剂分配器
公开(公告)号：US06460537B1
公开(公告)日：2002-10-08
申请号：US09437047
申请日：1999-11-09
申请人： Andrew M. Bryant , Anthony C. L. Wass , Peter D. Hodson
发明人： Andrew M. Bryant , Anthony C. L. Wass , Peter D. Hodson
IPC分类号： A61M1100
CPC分类号： A61M15/0091 , A61M15/0081 , A61M15/009 , A61M15/0093
摘要： A dispenser for dispensing a product from a pressurized product container comprising a housing defining a user port and adapted to have a pressurized product container mounted therein, the pressurized product container having a dispensing valve movable relative to the container between an open and a closed position; the housing further comprising a rolling member comprising a vane, and two associated rolling surfaces, the rolling member being capable of rotation in contact with the rolling surfaces such that they translate in opposite directions relative to the rolling member in response to inhalation through the user port, the rolling member being rotatable between a locking position in which the rolling member directly or indirectly engages the pressurized product container or valve to maintain the valve in the closed position, and a release position in which the valve and the pressurized product container move relative to each other so that the valve moves to the open position to dispense product from the container and towards the user port.
摘要翻译：一种用于从加压产品容器分配产品的分配器，包括限定用户端口并适于安装在其中的加压产品容器的壳体，所述加压产品容器具有可在打开和关闭位置之间相对于容器移动的分配阀; 所述壳体还包括滚动构件，所述滚动构件包括叶片和两个相关联的滚动表面，所述滚动构件能够旋转地与所述滚动表面接触，使得所述滚动构件响应于通过所述用户端口的吸入而相对于所述滚动构件在相反方向上平移所述滚动构件可在锁定位置之间旋转，在所述锁定位置中，所述滚动构件直接或间接地接合所述加压产品容器或阀，以将所述阀保持在关闭位置;以及释放位置，其中所述阀和所述加压产品容器相对于彼此使得阀移动到打开位置以从容器和用户端口分配产品。

3. 发明授权

US5482032A Dry powder inhalers 失效
标题翻译：干粉吸入器
公开(公告)号：US5482032A
公开(公告)日：1996-01-09
申请号：US273898
申请日：1994-07-12
申请人： David K. Smith , Peter D. Hodson , Anthony C. L. Wass
发明人： David K. Smith , Peter D. Hodson , Anthony C. L. Wass
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0026 , A61M15/0051 , A61M15/0055 , A61M2202/064
摘要： The present invention relates to a device for dislodging powder carried on the surface of a flexible sheet material. The device incorporates a resettable impactor including a head for striking the sheet material, wherein the head comprises an elongate striking surface which is curved in both planes orthoganol to the plan of the sheet material.
摘要翻译：本发明涉及一种用于移动在柔性片材表面上承载的粉末的装置。该装置包括可复位冲击器，其包括用于冲击片材的头部，其中头部包括细长的打击表面，该突出表面在与平板材料的平面的正交面的两个平面中弯曲。

4. 发明授权

US5408994A Inhalation device 失效
标题翻译：吸入装置
公开(公告)号：US5408994A
公开(公告)日：1995-04-25
申请号：US50440
申请日：1993-05-11
申请人： Anthony C. L. Wass , Brian R. Law , Eric A. Baum , Peter D. Hodson
发明人： Anthony C. L. Wass , Brian R. Law , Eric A. Baum , Peter D. Hodson
IPC分类号： A61M11/00 , A61M15/00
CPC分类号： A61M15/0091 , A61M15/009
摘要： An inhalation device for administration of aerosolized medicament to the respiratory system of a patient comprising a housing defining a patient port and an air inlet, the housing containing means for dispensing a dose of aerosolized medicament, an inhalation-activatable triggering mechanism for initiating the dispensing means, and reset means. The triggering mechanism comprises a vane mounted for pivotable movement between closed and open positions, the vane being positioned within the patient port such that inhalation through the patient port generates an airflow from the air inlet to the patient port causing pivotable movement of the vane. The device further includes an activator component moveable between a restrained position and a dispensing position which movement causes dispensing of medicament from the dispensing means, the activator component being biased towards its dispensing position.
摘要翻译： PCT No.PCT / GB91 / 01983 Sec。 371日期：1993年5月11日 102（e）日期1993年5月11日PCT 1991年11月12日PCT PCT。公开号WO92 / 08509 日期：1992年5月29日。一种用于向患者的呼吸系统施用雾化药物的吸入装置，包括限定患者口和空气入口的壳体，所述壳体容纳装置用于分配雾化药剂的剂量，可吸入激活的触发用于启动分配装置的机构和复位装置。触发机构包括安装成用于在闭合位置和打开位置之间可枢转运动的叶片，叶片定位在患者端口内，使得通过患者端口的吸入产生从空气入口到患者端口的气流，引起叶片的可枢转运动。该装置还包括可在限制位置和分配位置之间移动的活化剂组件，该运动导致药物从分配装置分配，活化剂组分被偏向其分配位置。

5. 发明授权

US5619984A Dry powder inhalation device having a powder-loaded elongate carrier 失效
标题翻译：具有粉末加载的细长载体的干粉吸入装置
公开(公告)号：US5619984A
公开(公告)日：1997-04-15
申请号：US437291
申请日：1995-05-08
申请人： Peter D. Hodson , David K. Smith , David J. Velasquez , Anthony C. L. Wass
发明人： Peter D. Hodson , David K. Smith , David J. Velasquez , Anthony C. L. Wass
IPC分类号： A61K9/14 , A61K45/08 , A61K47/30 , A61M15/00 , A61M15/02 , A61M16/00 , A61P11/00 , B05D7/14 , B65D83/06
CPC分类号： A61M15/0045 , A61M15/0006 , A61M15/0016 , A61M15/0025 , A61M15/0028 , A61M15/0043 , A61M15/0048 , A61M15/0051 , A61M15/0055 , A61M15/0066 , A61M15/0078 , A61M15/0085 , A61M15/0091 , A61M15/02 , A61M2016/0024 , A61M2202/064 , A61M2205/8206
摘要： A dry powder inhalation device comprising a housing defining a chamber in communication with a patient port in the form of a mouthpiece or nasal adaptor, and an elongate carrier bearing a powdered medicament, the device being constructed and arranged such that areas of predetermined size of the elongate carrier may sequentially be exposed within the chamber, the device comprising one or more air inlets such that when a patient inhales through the patient port an air flow is established from the air inlet(s) to the patient port through the chamber such that particles of the powdered medicament of respirable size from said exposed area of the elongate carrier are entrained within the air flow.
摘要翻译：一种干粉吸入装置，其特征在于，包括壳体，所述壳体限定与所述口部或鼻部适配器形式的患者端口连通的室，以及承载有粉末状药物的细长载体，所述装置被构造和布置成使得预定尺寸的细长的载体可以顺序地在腔室内暴露，该装置包括一个或多个空气入口，使得当患者通过患者端口吸入时，通过腔室从空气入口到患者端口建立空气流，使得颗粒的来自所述细长载体的所述暴露区域的可吸入尺寸的粉末状药物被夹带在空气流中。

6. 发明授权

US08814009B2 Metered dose valve 有权
标题翻译：计量剂量阀
公开(公告)号：US08814009B2
公开(公告)日：2014-08-26
申请号：US12681280
申请日：2008-10-02
申请人： Peter D. Hodson , Matthew A. Goring , Stephen J. Howgill , John Fielding , Richard D. Brewer , Rachael V. Shaw , Paul A. Charnock , Stuart A. McGlasson , Stephen D. Helm , Graham V. Jackson , Anthony W. Balkwill , Jason A. Graves
发明人： Peter D. Hodson , Matthew A. Goring , Stephen J. Howgill , John Fielding , Richard D. Brewer , Rachael V. Shaw , Paul A. Charnock , Stuart A. McGlasson , Stephen D. Helm , Graham V. Jackson , Anthony W. Balkwill , Jason A. Graves
IPC分类号： B65D83/00
CPC分类号： A61M15/009 , B65D83/54
摘要： An aerosol metering valve comprising: (a) a valve stem movable between a rest position and a firing position comprising: a body portion comprising a circumferential sealing surface (b) a valve body comprising: a body wall, and an internal chamber defined at least in part by the body wall; and (c) a metering gasket having an inner periphery defining an aperture, being disposed near the most interior end of the internal chamber and being configured to be able to form a transient, substantially fluid-tight face seal against the circumferential sealing surface of the valve stem, where at the rest position of the valve stem, the body portion of the valve stem is located within the internal chamber and as the valve stem is moved from its rest position towards its firing position the circumferential sealing surface of the valve stem contacts the metering gasket to form a face seal thereby closing a metering chamber and thereafter further movement of the valve stem towards its firing position causes the metering gasket to deflect while maintaining the seal with the circumferential sealing surface of the valve stem; and wherein the metering gasket in an unbiased configuration is an annular disc having a substantially planar form and where the valve is constructed and arranged such that the inner periphery of the metering gasket is urged out of said substantially planar form at the rest position of the valve stem, or wherein the metering gasket is pre-biased into a dished-shape.
摘要翻译：一种气溶胶计量阀，包括：（a）可在静止位置和击发位置之间移动的阀杆，包括：主体部分，其包括周向密封表面（b）阀体，所述阀体包括：主体壁和至少限定的内部腔部分由身体壁; 和（c）具有限定孔的内周边的计量垫片，其设置在内室的最内端附近，并且构造成能够形成一个瞬时的，基本上是流体密封的，面对密封面阀杆，其中在阀杆的静止位置处，阀杆的主体部分位于内部腔室内，并且当阀杆从其静止位置朝向其击发位置移动时，阀杆的圆周密封表面接触计量垫圈以形成面密封件，从而封闭计量室，此后阀杆朝向其点火位置的进一步运动导致计量垫片偏转，同时保持与阀杆的周向密封表面的密封; 并且其中所述计量垫片为无偏置构型，是具有基本上平面形状的环形盘，并且所述阀被构造和布置成使得所述计量垫片的内周边在所述阀的静止位置处被推出所述基本平坦的形式杆，或其中计量垫片预偏置成碟形。

7. 发明申请

US20110042419A1 METERED DOSE VALVE 有权
标题翻译：计量式阀门
公开(公告)号：US20110042419A1
公开(公告)日：2011-02-24
申请号：US12681280
申请日：2008-10-02
申请人： Peter D. Hodson , Matthew A. Goring , Stephen J. Howgill , John Fielding , Rachel V. Shaw , Paul A. Charnock , Stuart A. McGlasson , Stephen D. Helm , Graham V. Jackson , Anthony W. Balkwill , Jason A. Graves
发明人： Peter D. Hodson , Matthew A. Goring , Stephen J. Howgill , John Fielding , Rachel V. Shaw , Paul A. Charnock , Stuart A. McGlasson , Stephen D. Helm , Graham V. Jackson , Anthony W. Balkwill , Jason A. Graves
IPC分类号： B65D83/00
CPC分类号： A61M15/009 , B65D83/54
摘要： An aerosol metering valve comprising: (a) a valve stem movable between a rest position and a firing position comprising: a body portion comprising a circumferential sealing surface (b) a valve body comprising: a body wall, and an internal chamber defined at least in part by the body wall; and (c) a metering gasket having an inner periphery defining an aperture, being disposed near the most interior end of the internal chamber and being configured to be able to form a transient, substantially fluid-tight face seal against the circumferential sealing surface of the valve stem, where at the rest position of the valve stem, the body portion of the valve stem is located within the internal chamber and as the valve stem is moved from its rest position towards its firing position the circumferential sealing surface of the valve stem contacts the metering gasket to form a face seal thereby closing a metering chamber and thereafter further movement of the valve stem towards its firing position causes the metering gasket to deflect while maintaining the seal with the circumferential sealing surface of the valve stem; and wherein the metering gasket in an unbiased configuration is an annular disc having a substantially planar form and where the valve is constructed and arranged such that the inner periphery of the metering gasket is urged out of said substantially planar form at the rest position of the valve stem, or wherein the metering gasket is pre-biased into a dished-shape.
摘要翻译：一种气溶胶计量阀，包括：（a）可在静止位置和击发位置之间移动的阀杆，包括：主体部分，其包括周向密封表面（b）阀体，所述阀体包括：主体壁和至少限定的内部腔部分由身体壁; 和（c）具有限定孔的内周边的计量垫片，其设置在内室的最内端附近，并且构造成能够形成一个瞬时的，基本上是流体密封的，面对密封面阀杆，其中在阀杆的静止位置处，阀杆的主体部分位于内部腔室内，并且当阀杆从其静止位置朝向其击发位置移动时，阀杆的圆周密封表面接触计量垫圈以形成面密封件，从而封闭计量室，此后阀杆朝向其点火位置的进一步运动导致计量垫片偏转，同时保持与阀杆的周向密封表面的密封; 并且其中所述计量垫片为无偏置构型，是具有基本上平面形状的环形盘，并且所述阀被构造和布置成使得所述计量垫片的内周边在所述阀的静止位置处被推出所述基本平坦的形式杆，或其中计量垫片预偏置成碟形。

8. 发明申请

US20080202515A1 Inhalation Device 审中-公开
标题翻译：吸入装置
公开(公告)号：US20080202515A1
公开(公告)日：2008-08-28
申请号：US11721991
申请日：2005-12-12
申请人： Peter D. Hodson , Stephen J. Howgill , Graham R. Purkins
发明人： Peter D. Hodson , Stephen J. Howgill , Graham R. Purkins
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0003 , A61M15/0026 , A61M15/0033 , A61M15/005 , A61M15/0051 , A61M15/0075 , A61M15/0091 , A61M15/0096 , A61M2205/581 , A61M2205/582 , A61M2205/8218
摘要： An inhalation device (1) comprising two or more hermetically sealed receptacles (39), each receptacle containing a single dose of a pressurized formulation comprising a pharmaceutically active ingredient and a liquefied aerosol propellant consisting of HFA 134a, HFA 227 or a mixture thereof and wherein at least a portion (39a) of each receptacle is perforable.
摘要翻译：一种吸入装置（1），包括两个或更多个气密密封的容器（39），每个容器包含单剂量的包含药物活性成分的加压制剂和由HFA134a，HFA222或其混合物组成的液化气溶胶推进剂，其中每个容器的至少一部分（39a）是可穿孔的。

9. 发明申请

US20090173346A1 DOSE COUNTER 有权
标题翻译：剂量计数器
公开(公告)号：US20090173346A1
公开(公告)日：2009-07-09
申请号：US12297942
申请日：2007-04-20
申请人： Adam J. Stuart , Graham R. Purkins , Rachel V. Striebig , Stephen J. Howgill , Peter D. Hodson , Richard D. Brewer , Benjamin J. Holden
发明人： Adam J. Stuart , Graham R. Purkins , Rachel V. Striebig , Stephen J. Howgill , Peter D. Hodson , Richard D. Brewer , Benjamin J. Holden
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0073 , A61M15/0075 , A61M15/009 , B65D83/46 , B65D83/54 , B65D83/75 , G06M1/16 , G06M1/24
摘要： This application discloses a dose counter for use in connection with a device adapted for metered dispensing of a medication. The dose counter has a first count indicator that has a first indicia bearing surface, with the first count indicator being rotatable about a first axis. The dose counter also has a second count indicator that has a second indicia bearing surface, with the second count indicator being rotatable about a second axis. The second axis is disposed at an obtuse angle with respect to the first axis, and the first and second indicia bearing surfaces align at a common viewing area to collectively present at least a portion of a medication dosage count.
摘要翻译：本申请公开了一种与适用于药物计量分配的装置相结合使用的剂量计数器。剂量计数器具有第一计数指示器，其具有第一标记支承表面，第一计数指示器可围绕第一轴线旋转。剂量计数器还具有第二计数指示器，其具有第二标记支承表面，第二计数指示器可绕第二轴线旋转。第二轴相对于第一轴以钝角设置，并且第一和第二标记支承表面在共同的观察区域对齐，以共同呈现药物剂量计数的至少一部分。

10. 发明授权

US08479732B2 Dose counter 有权
公开(公告)号：US08479732B2
公开(公告)日：2013-07-09
申请号：US12297942
申请日：2007-04-20
申请人： Adam J. Stuart , Graham R. Purkins , Rachel V. Striebig , Stephen J. Howgill , Peter D. Hodson , Richard D. Brewer , Benjamin J. Holden
发明人： Adam J. Stuart , Graham R. Purkins , Rachel V. Striebig , Stephen J. Howgill , Peter D. Hodson , Richard D. Brewer , Benjamin J. Holden
IPC分类号： A62B9/00 , G09F9/00
CPC分类号： A61M15/0065 , A61M15/0073 , A61M15/0075 , A61M15/009 , B65D83/46 , B65D83/54 , B65D83/75 , G06M1/16 , G06M1/24
摘要： A dose counter for use in connection with a device adapted for metered dispensing of a medication is described. The dose counter has a first count indicator that has a first indicia bearing surface, with the first count indicator being rotatable about a first axis. The dose counter also has a second count indicator that has a second indicia bearing surface, with the second count indicator being rotatable about a second axis. The second axis is disposed at an obtuse angle with respect to the first axis, and the first and second indicia bearing surfaces align at a common viewing area to collectively present at least a portion of a medication dosage count.

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