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1. 发明公开

US20240001126A1 METHOD AND DEVICE FOR MANAGING HIS BUNDLE PACING IN A NON-TRACKING MODE DURING AF/AT 审中-公开
公开(公告)号：US20240001126A1
公开(公告)日：2024-01-04
申请号：US18468782
申请日：2023-09-18
申请人： Pacesetter, Inc.
发明人： Aditya Goil , Xiaoyi Min , Wenwen Li , Yun Qiao , Jan O. Mangual-Soto , Carin Folman
IPC分类号： A61N1/365 , A61B5/00 , A61N1/05 , A61B5/283
CPC分类号： A61N1/365 , A61B5/686 , A61N1/056 , A61B5/283
摘要： System and methods are provided herein and include a HIS electrode configured to be located proximate to a HIS bundle and to at least partially define a HIS sensing vector. They system includes memory to store program instructions and cardiac activity (CA) signals for a series of beats utilizing a candidate sensing configuration. The candidate sensing configuration is defined by i) the HIS sensing vector and ii) a sensing channel that utilizes sensing circuitry configured to operate based on one or more sensing settings to detect near field and far field activity. The system includes one or more processors that, when executing the program instructions, are configured to analyze the CA signals to obtain an atrial (A) feature of interest (FOI) and a ventricular (V) FOI for the corresponding beats within the series of beats and identify a V-A FOI relation between the A FOIs and the V FOIs across the series of beats. The system adjusts the candidate sensing configuration and repeat the obtain, analyze and identify operations to obtain a collection of V-A FOI relations for a corresponding collection of candidate sensing configurations and selects a resultant sensing configuration from the collection of candidate sensing configurations based on one or more criteria, the resultant sensing configuration to be utilized to manage HIS bundle pacing during an atrial arrhythmia.

2. 发明授权

US11712568B2 Implantable medical systems and methods for use therewith that detect atrial capture and AV node capture responsive to his bundle pacing 有权
公开(公告)号：US11712568B2
公开(公告)日：2023-08-01
申请号：US17171773
申请日：2021-02-09
申请人： Pacesetter, Inc.
发明人： Yun Qiao , Wenwen Li , Jan Mangual , Luke C. McSpadden
IPC分类号： A61N1/00 , A61N1/37
CPC分类号： A61N1/3714
摘要： Certain embodiments of the present technology described herein relate to detecting atrial oversensing in a His intracardiac electrogram (His IEGM), characterizing atrial oversensing, determining when atrial oversensing is likely to occur, and or reducing the chance of atrial oversensing occurring. Some such embodiments characterize and/or avoid atrial oversensing within a His IEGM. Other embodiments of the present technology described herein relate to determining whether atrial capture occurs in response to His bundle pacing (HBP). Still other embodiments of the present technology described herein relate to determining whether AV node capture occurs in response to HBP.

3. 发明授权

US11878174B2 Implantable medical systems and methods used to detect, characterize or avoid atrial oversensing within a His IEGM 有权
公开(公告)号：US11878174B2
公开(公告)日：2024-01-23
申请号：US17171762
申请日：2021-02-09
申请人： Pacesetter, Inc.
发明人： Yun Qiao , Wenwen Li , Jan Mangual , Luke C. McSpadden
IPC分类号： A61N1/37 , A61N1/368 , A61N1/05 , A61B5/33 , A61B5/283
CPC分类号： A61N1/3714 , A61B5/283 , A61B5/33 , A61N1/056 , A61N1/3682 , A61N1/3688
摘要： Certain embodiments of the present technology described herein relate to detecting atrial oversensing in a His intracardiac electrogram (His IEGM), characterizing atrial oversensing, determining when atrial oversensing is likely to occur, and or reducing the chance of atrial oversensing occurring. Some such embodiments characterize and/or avoid atrial oversensing within a His IEGM. Other embodiments of the present technology described herein relate to determining whether atrial capture occurs in response to His bundle pacing (HBP). Still other embodiments of the present technology described herein relate to determining whether AV node capture occurs in response to HBP.

4. 发明申请

US20230008264A1 METHOD AND SYSTEM FOR IMPLANTING A SEPTAL WALL ELECTRODE 有权
公开(公告)号：US20230008264A1
公开(公告)日：2023-01-12
申请号：US17367855
申请日：2021-07-06
申请人： Pacesetter, Inc.
发明人： Jan O. Mangual-Soto , Wenwen Li , Yun Qiao , Kyungmoo Ryu
IPC分类号： A61N1/37 , A61N1/375 , A61N1/05
摘要： A system is provided that includes a first electrode configured to be located within a septal wall, and a second electrode configured to be located outside of the septal wall. The system also includes an impedance circuit configured to measure impedance along an impedance monitoring (IM) vector between the first and second electrodes. One or more processors are also provided that are configured to obtain impedance data indicative of an impedance along the IM vector with the first electrode located at different depths within the septal wall, the impedance data including a set of data values associated with different depths of the first electrode within the septal wall. The one or more processors are also configured to determine when the first electrode is located at a target depth within the septal wall based on the impedance data.

5. 发明申请

US20220072303A1 METHOD AND DEVICE FOR MANAGING HIS BUNDLE PACING IN A NON-TRACKING MODE DURING AF/AT 有权
公开(公告)号：US20220072303A1
公开(公告)日：2022-03-10
申请号：US17014007
申请日：2020-09-08
申请人： Pacesetter, Inc.
发明人： Aditya Goil , Xiaoyi Min , Wenwen Li , Yun Qiao , Jan O. Mangual-Soto , Carin Folman
IPC分类号： A61N1/365 , A61N1/05 , A61B5/042 , A61B5/00
摘要： System and methods are provided herein and include a HIS electrode configured to be located proximate to a HIS bundle and to at least partially define a HIS sensing vector. They system includes memory to store program instructions and cardiac activity (CA) signals for a series of beats utilizing a candidate sensing configuration. The candidate sensing configuration is defined by i) the HIS sensing vector and ii) a sensing channel that utilizes sensing circuitry configured to operate based on one or more sensing settings to detect near field and far field activity. The system includes one or more processors that, when executing the program instructions, are configured to analyze the CA signals to obtain an atrial (A) feature of interest (FOI) and a ventricular (V) FOI for the corresponding beats within the series of beats and identify a V-A FOI relation between the A FOIs and the V FOIs across the series of beats. The system adjusts the candidate sensing configuration and repeat the obtain, analyze and identify operations to obtain a collection of V-A FOI relations for a corresponding collection of candidate sensing configurations and selects a resultant sensing configuration from the collection of candidate sensing configurations based on one or more criteria, the resultant sensing configuration to be utilized to manage HIS bundle pacing during an atrial arrhythmia.

6. 发明授权

US11654288B2 Systems and methods for managing atrial-ventricular delay adjustments 有权
公开(公告)号：US11654288B2
公开(公告)日：2023-05-23
申请号：US16988821
申请日：2020-08-10
申请人： Pacesetter, Inc.
发明人： Wenwen Li , Nima Badie , Luke C. McSpadden , Yun Qiao , Avi Fischer , Kyungmoo Ryu
IPC分类号： A61N1/368 , A61N1/05
CPC分类号： A61N1/3682 , A61N1/0587 , A61N1/36843
摘要： A system and method are provided for managing atrial-ventricular (AV) delay adjustments. An AV interval is measured that corresponds to an interval between an atrial paced (Ap) event or an atrial sensed (As) event and a sensed ventricular (Vs) event. A candidate AV delay is set based on the AV interval and a bundle branch adjustment (BBA) value. A QRS characteristic of interest (COI) is measured while utilizing the candidate AV delay in connection with delivering a pacing therapy. The BBA value is adjusted and the candidate AV delay is reset based on the BBA value as adjusted. A collection of QRS COIs and corresponding candidate AV delays are obtained and one of the candidate AV delays is selected as a BBA AV delay. The pacing therapy is managed, based on the BBA AV delay.

7. 发明申请

US20230121674A1 IMPLANTABLE MEDICAL DEVICES, SYSTEMS AND METHODS FOR REDUCING T-WAVE OVERSENSING AND ARRHYTHMIA UNDERSENSING 有权
公开(公告)号：US20230121674A1
公开(公告)日：2023-04-20
申请号：US17744217
申请日：2022-05-13
申请人： Pacesetter, Inc.
发明人： Yun Qiao , Nima Badie , Wenwen Li , Chaoyi Kang , Jan Mangual , Fady Dawoud
IPC分类号： A61B5/29 , A61B5/33 , A61B5/335 , A61B5/363 , A61B5/352 , A61B5/355 , A61B5/361
摘要： Described herein are implantable medical devices and systems, and methods for use therewith, for reducing T-wave oversensing and arrythmia undersensing that occur due to inappropriate filtering of a signal indicative of cardiac electrical activity. A method includes obtaining a signal indicative of cardiac electrical activity, and using a first bandpass filter to produce a first filtered version thereof, using a second bandpass filter to produce a second filtered version thereof, wherein the first bandpass filter passes frequencies within a first frequency range, and the second bandpass filter passes frequencies within a second frequency range that is wider than the first frequency range. The method also includes selectively changing from using the first filtered version of the signal to monitor for a VS event, to using the second filtered version of the signal to monitor for a VS event, based on first criteria, and vice versa, based on second criteria.

8. 发明授权

US11517268B2 Method and device for detecting premature ventricular contractions based on beat distribution characteristics 有权
公开(公告)号：US11517268B2
公开(公告)日：2022-12-06
申请号：US16262645
申请日：2019-01-30
申请人： PACESETTER, INC.
发明人： Yun Qiao , Fujian Qu , Stuart Rosenbeg
IPC分类号： A61B5/00 , A61B5/283 , A61B5/364
摘要： A computer implemented method and system for detecting premature ventricular contractions (PVCs) are provided. The method is under control of one or more processors configured with specific executable instructions. The method obtains a cycle length (CL) distribution metric that plots a series of cardiac beats into one of a set of transition types based on R-R interval (RRI) difference pairs associated with the cardiac beats. The CL distribution metric plots the cardiac beats based on a comparison between combinations of the RRI difference pairs for corresponding combinations of the cardiac beats. The method calculates a distribution characteristic for the cardiac beats, from the series of cardiac beats that exhibit a first transition type from the set of transition types and calculates a discrimination score based on the distribution characteristic of the cardiac beats across the CL distribution metric. The method designates the CA signals to include a predetermined level of PVC burden based on the discrimination score.

9. 发明申请

US20220249850A1 IMPLANTABLE MEDICAL SYSTEMS AND METHODS FOR USE THEREWITH THAT DETECT ATRIAL CAPTURE AND AV NODE CAPTURE RESPONSIVE TO HIS BUNDLE PACING 有权
公开(公告)号：US20220249850A1
公开(公告)日：2022-08-11
申请号：US17171773
申请日：2021-02-09
申请人： Pacesetter, Inc.
发明人： Yun Qiao , Wenwen Li , Jan Mangual , Luke C. McSpadden
IPC分类号： A61N1/37
摘要： Certain embodiments of the present technology described herein relate to detecting atrial oversensing in a His intracardiac electrogram (His IEGM), characterizing atrial oversensing, determining when atrial oversensing is likely to occur, and or reducing the chance of atrial oversensing occurring. Some such embodiments characterize and/or avoid atrial oversensing within a His IEGM. Other embodiments of the present technology described herein relate to determining whether atrial capture occurs in response to His bundle pacing (HBP). Still other embodiments of the present technology described herein relate to determining whether AV node capture occurs in response to HBP.

10. 发明申请

US20210393967A1 SYSTEMS AND METHODS FOR IMPROVED HIS BUNDLE AND BACKUP PACING TIMING 有权
公开(公告)号：US20210393967A1
公开(公告)日：2021-12-23
申请号：US16904837
申请日：2020-06-18
申请人： Pacesetter, Inc.
发明人： Xiaoyi Min , Wenwen Li , Yun Qiao , Aditya Goil
IPC分类号： A61N1/37 , A61N1/365 , A61N1/39
摘要： A system and method are provided. The system includes a HIS electrode configured to be located proximate to a HIS bundle. A pulse generator is coupled to the HIS electrode and is configured to deliver HIS bundle pacing (HBP), a right atrial (RA) electrode is located in a right atrium, a sensing circuitry coupled to the RA electrode and defines an RA sensing channel that does not utilize the HIS electrode. The system includes a memory including program instructions. The system includes a processor is configured to collect cardiac activity (CA) signals over the RA sensing channel utilizing the RA electrode. The CA signals include a far field (FF) component associated with a ventricular event (VE). The processor analyzes the FF component to identify first and second FF component (FFC) characteristics of interest (COI) of the ventricular event and utilizes the first FFC COI to apply a first capture class (CC) discriminator to distinguish between first and second capture classes. The first capture class includes first and second capture types. The processor utilizes the second FFC COI to apply a second CC discriminator to distinguish between at least one of i) the first and second capture types within the first capture class, or ii) third and fourth capture classes and manages HIS bundle pacing based on distinctions by the first and second CC discriminators.

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