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1. 发明申请

US20090020439A1 ELECTROCHEMICAL BIOSENSOR ANALYSIS SYSTEM 有权
标题翻译：电化学生物传感器分析系统
公开(公告)号：US20090020439A1
公开(公告)日：2009-01-22
申请号：US12177566
申请日：2008-07-22
申请人： Michael Marquant , Udo Zapf , Gregor Bainczyk , Volker Unkrig , Mihail-Onoriu Lungu , Holger Kotzan
发明人： Michael Marquant , Udo Zapf , Gregor Bainczyk , Volker Unkrig , Mihail-Onoriu Lungu , Holger Kotzan
IPC分类号： G01N27/26 , G01N27/327
CPC分类号： C12Q1/001 , G01N27/3273 , G01N27/3274
摘要： An electrochemical biosensor analysis system is provided for analyzing a sample liquid, comprising a biosensor having an electrode structure made of at least two electrodes, a test field, covering the electrode structure and capable of absorbing the sample liquid, and a defined sample application surface on the top side of the test field. The system also includes an analysis instrument comprising an evaluation unit for determining the desired analysis data. The analysis instrument comprises an AC resistance measuring device for measuring an AC resistance value between two electrodes of the electrode structure by means of an area compensation measurement. The measured AC resistance value is used, in the determination of the analysis data, as a measure of the partial area of the effective electrode structure area wetted by the sample liquid.
摘要翻译：提供一种用于分析样品液体的电化学生物传感器分析系统，其包括具有由至少两个电极制成的电极结构的生物传感器，覆盖电极结构并能够吸收样品液体的测试场，以及定义的样品施加表面测试领域的顶端。该系统还包括分析仪器，其包括用于确定所需分析数据的评估单元。分析仪器包括用于通过面积补偿测量来测量电极结构的两个电极之间的交流电阻值的交流电阻测量装置。在测定分析数据时，使用测量的AC电阻值作为由样品液体润湿的有效电极结构区域的部分面积的量度。

2. 发明授权

US08357274B2 Electrochemical biosensor analysis system 有权
标题翻译：电化学生物传感器分析系统
公开(公告)号：US08357274B2
公开(公告)日：2013-01-22
申请号：US12177566
申请日：2008-07-22
申请人： Michael Marquant , Udo Zapf , Gregor Bainczyk , Volker Unkrig , Mihail-Onoriu Lungu , Holger Kotzan
发明人： Michael Marquant , Udo Zapf , Gregor Bainczyk , Volker Unkrig , Mihail-Onoriu Lungu , Holger Kotzan
IPC分类号： G01N27/327
CPC分类号： C12Q1/001 , G01N27/3273 , G01N27/3274
摘要： An electrochemical biosensor analysis system is provided for analyzing a sample liquid, comprising a biosensor having an electrode structure made of at least two electrodes, a test field, covering the electrode structure and capable of absorbing the sample liquid, and a defined sample application surface on the top side of the test field. The system also includes an analysis instrument comprising an evaluation unit for determining the desired analysis data. The analysis instrument comprises an AC resistance measuring device for measuring an AC resistance value between two electrodes of the electrode structure by means of an area compensation measurement. The measured AC resistance value is used, in the determination of the analysis data, as a measure of the partial area of the effective electrode structure area wetted by the sample liquid.
摘要翻译：提供一种用于分析样品液体的电化学生物传感器分析系统，其包括具有由至少两个电极制成的电极结构的生物传感器，覆盖电极结构并能够吸收样品液体的测试场，以及定义的样品施加表面测试领域的顶端。该系统还包括分析仪器，其包括用于确定所需分析数据的评估单元。分析仪器包括用于通过面积补偿测量来测量电极结构的两个电极之间的交流电阻值的交流电阻测量装置。在测定分析数据时，使用测量的AC电阻值作为由样品液体润湿的有效电极结构区域的部分面积的量度。

3. 发明授权

US07892849B2 Reagent stripe for test strip 有权
标题翻译：试纸条试纸条
公开(公告)号：US07892849B2
公开(公告)日：2011-02-22
申请号：US12389954
申请日：2009-02-20
申请人： David W. Burke , Michael Marquant , Udo Zapf , Michael Fritz , Dan Mosoiu , Chris Wilsey
发明人： David W. Burke , Michael Marquant , Udo Zapf , Michael Fritz , Dan Mosoiu , Chris Wilsey
IPC分类号： G01N33/48
CPC分类号： G01N33/558 , G01N27/3271 , Y10T156/1059 , Y10T156/1084
摘要： A test strip having a small sample-receiving chamber on the order of less than 1 microliter. The inventive test strip includes a reagent layer that extends across the width of the test strip and also extends to the sample-receiving end, such that the edges of the reagent layer are aligned with the side and dose receiving edges of the test strip. The hydrophilic reagent extending to the dosing edge of the strip promotes wicking of the sample into the test strip. The end and side edges of the reagent layer are preferably formed as part of a cutting process that forms individual test strips from a larger web, which results in a smooth and thin reagent layer with a uniform thickness, substantially covering the entire floor of the sample-receiving chamber. The inventive mass production process helps improve the reproducibility of the quantity, location, thickness and other properties of the reagent layer, which in turn improves the accuracy of the test result.
摘要翻译：具有小于1微升量级的小样品接收室的测试条。本发明的测试条包括跨越测试条的宽度延伸并且还延伸到样品接收端的试剂层，使得试剂层的边缘与测试条的侧面和剂量接收边缘对准。延伸到条带的配量边缘的亲水试剂促进样品的芯吸到测试条中。试剂层的端部和侧边缘优选形成为从较大纤维网形成单独的测试条的切割过程的一部分，其导致具有均匀厚度的平滑和薄的试剂层，基本覆盖样品的整个底板接收室本发明的批量生产方法有助于提高试剂层的数量，位置，厚度和其他性质的再现性，从而提高了测试结果的准确性。

4. 发明申请

US20090151864A1 REAGENT STRIPE FOR TEST STRIP 有权
标题翻译：用于测试条的试纸条
公开(公告)号：US20090151864A1
公开(公告)日：2009-06-18
申请号：US12389954
申请日：2009-02-20
申请人： David W. Burke , Michael Marquant , Udo Zapf , Michael Fritz , Dan Mosoiu , Chris Wilsey
发明人： David W. Burke , Michael Marquant , Udo Zapf , Michael Fritz , Dan Mosoiu , Chris Wilsey
IPC分类号： B32B37/00
CPC分类号： G01N33/558 , G01N27/3271 , Y10T156/1059 , Y10T156/1084
摘要： A test strip having a small sample-receiving chamber on the order of less than 1 microliter. The inventive test strip includes a reagent layer that extends across the width of the test strip and also extends to the sample-receiving end, such that the edges of the reagent layer are aligned with the side and dose receiving edges of the test strip. The hydrophilic reagent extending to the dosing edge of the strip promotes wicking of the sample into the test strip. The end and side edges of the reagent layer are preferably formed as part of a cutting process that forms individual test strips from a larger web, which results in a smooth and thin reagent layer with a uniform thickness, substantially covering the entire floor of the sample-receiving chamber. The inventive mass production process helps improve the reproducibility of the quantity, location, thickness and other properties of the reagent layer, which in turn improves the accuracy of the test result.
摘要翻译：具有小于1微升量级的小样品接收室的测试条。本发明的测试条包括跨越测试条的宽度延伸并且还延伸到样品接收端的试剂层，使得试剂层的边缘与测试条的侧面和剂量接收边缘对准。延伸到条带的配量边缘的亲水试剂促进样品的芯吸到测试条中。试剂层的端部和侧边缘优选形成为从较大纤维网形成单独的测试条的切割过程的一部分，其导致具有均匀厚度的平滑和薄的试剂层，基本覆盖样品的整个底板接收室本发明的批量生产方法有助于提高试剂层的数量，位置，厚度和其他性质的再现性，从而提高了测试结果的准确性。

5. 发明授权

US07727467B2 Reagent stripe for test strip 有权
标题翻译：试纸条试纸条
公开(公告)号：US07727467B2
公开(公告)日：2010-06-01
申请号：US10871673
申请日：2004-06-18
申请人： David W. Burke , Michael Marquant , Udo Zapf , Michael Fritz , Dan Mosoiu , Chris Wilsey
发明人： David W. Burke , Michael Marquant , Udo Zapf , Michael Fritz , Dan Mosoiu , Chris Wilsey
IPC分类号： G01N33/48
CPC分类号： G01N33/558 , G01N27/3271 , Y10T156/1059 , Y10T156/1084
摘要： A test strip having a small sample-receiving chamber on the order of less than 1 microliter. The inventive test strip includes a reagent layer that extends across the width of the test strip and also extends to the sample-receiving end, such that the edges of the reagent layer are aligned with the side and dose receiving edges of the test strip. The hydrophilic reagent extending to the dosing edge of the strip promotes wicking of the sample into the test strip. The end and side edges of the reagent layer are preferably formed as part of a cutting process that forms individual test strips from a larger web, which results in a smooth and thin reagent layer with a uniform thickness, substantially covering the entire floor of the sample-receiving chamber. The inventive mass production process helps improve the reproducibility of the quantity, location, thickness and other properties of the reagent layer, which in turn improves the accuracy of the test result.
摘要翻译：具有小于1微升量级的小样品接收室的测试条。本发明的测试条包括跨越测试条的宽度延伸并且还延伸到样品接收端的试剂层，使得试剂层的边缘与测试条的侧面和剂量接收边缘对准。延伸到条带的配量边缘的亲水试剂促进样品的芯吸到测试条中。试剂层的端部和侧边缘优选形成为从较大纤维网形成单独的测试条的切割过程的一部分，其导致具有均匀厚度的平滑和薄的试剂层，基本覆盖样品的整个底板接收室本发明的批量生产方法有助于提高试剂层的数量，位置，厚度和其他性质的再现性，从而提高了测试结果的准确性。

6. 发明申请

US20050016844A1 Reagent stripe for test strip 有权
标题翻译：试纸条试纸条
公开(公告)号：US20050016844A1
公开(公告)日：2005-01-27
申请号：US10871673
申请日：2004-06-18
申请人： David Burke , Michael Marquant , Udo Zapf , Michael Fritz , Dan Mosoiu , Chris Wilsey
发明人： David Burke , Michael Marquant , Udo Zapf , Michael Fritz , Dan Mosoiu , Chris Wilsey
IPC分类号： G01N27/26 , G01N31/22 , G01N33/00 , G01N33/487 , G01N33/558
CPC分类号： G01N33/558 , G01N27/3271 , Y10T156/1059 , Y10T156/1084
摘要： A test strip having a small sample-receiving chamber on the order of less than 1 microliter. The inventive test strip includes a reagent layer that extends across the width of the test strip and also extends to the sample-receiving end, such that the edges of the reagent layer are aligned with the side and dose receiving edges of the test strip. The hydrophilic reagent extending to the dosing edge of the strip promotes wicking of the sample into the test strip. The end and side edges of the reagent layer are preferably formed as part of a cutting process that forms individual test strips from a larger web, which results in a smooth and thin reagent layer with a uniform thickness, substantially covering the entire floor of the sample-receiving chamber. The inventive mass production process helps improve the reproducibility of the quantity, location, thickness and other properties of the reagent layer, which in turn improves the accuracy of the test result.
摘要翻译：具有小于1微升量级的小样品接收室的测试条。本发明的测试条包括跨越测试条的宽度延伸并且还延伸到样品接收端的试剂层，使得试剂层的边缘与测试条的侧面和剂量接收边缘对准。延伸到条带的配量边缘的亲水试剂促进样品的芯吸到测试条中。试剂层的端部和侧边缘优选形成为从较大纤维网形成单独的测试条的切割过程的一部分，其导致具有均匀厚度的平滑和薄的试剂层，基本覆盖样品的整个底板接收室本发明的批量生产方法有助于提高试剂层的数量，位置，厚度和其他性质的再现性，从而提高了测试结果的准确性。

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