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1. 发明申请

US20100081867A1 Medical Device Delivery System Having Integrated Introducer 失效
标题翻译：具有综合介绍者的医疗器械输送系统
公开(公告)号：US20100081867A1
公开(公告)日：2010-04-01
申请号：US12565669
申请日：2009-09-23
申请人： Matthew G. Fishler , Alan R. Klenk , Joshua Wallin , Peter M. Martin
发明人： Matthew G. Fishler , Alan R. Klenk , Joshua Wallin , Peter M. Martin
IPC分类号： A61F2/00
CPC分类号： A61B17/00234 , A61B17/0293 , A61B17/3468 , A61B2017/00243 , A61B2017/308 , A61F2/2481 , A61F2002/2484
摘要： An apparatus for delivering a medical device onto a heart includes a housing within which is releasably disposed the medical device. The housing in one embodiment comprises inner and outer deflectors between which is delivered the medical device. Both deflectors are self-expanding. A deflector compression sheath is slidable longitudinally over the housing to a delivery position at which it moves the deflectors to a collapsed configuration. The compression sheath is retracted to a deployment position to permit the deflectors to deploy by self-expanding to their larger diameters. The outer deflector has an expanded diameter sufficient to engage the inner surface of the pericardium to hold it away from the delivery site while the second deflector guides the medical device into position over the heart while protecting the heart. In another embodiment, the housing includes only an outer deflector. The apparatus also functions as an introducer when the compression sheath is moved to the delivery or “introducer” position at which configuration, the apparatus functions as an introducer.
摘要翻译：用于将医疗装置递送到心脏上的装置包括壳体，其中可释放地设置在医疗装置上。一个实施例中的壳体包括内部和外部偏转器，在其间输送医疗装置。两个导流板都是自扩展的。偏转器压缩护套可以在壳体上纵向滑动到输送位置，在该输送位置，偏转器将偏转器移动到收缩构型。压缩护套缩回到展开位置，以允许偏转器通过自扩张而展开成较大的直径。外导流器具有足以接合心包内表面的扩张直径以将其远离输送部位，而第二导流器将医疗装置引导到心脏上方的位置，同时保护心脏。在另一个实施例中，壳体仅包括外部偏转器。当压缩护套移动到输送或“导引器”位置时，该装置还用作导引器，在该位置处，该装置用作导引器。

2. 发明授权

US08192351B2 Medical device delivery system having integrated introducer 失效
标题翻译：具有集成导引器的医疗器械输送系统
公开(公告)号：US08192351B2
公开(公告)日：2012-06-05
申请号：US12565669
申请日：2009-09-23
申请人： Matthew G. Fishler , Alan R. Klenk , Joshua Wallin , Peter M. Martin
发明人： Matthew G. Fishler , Alan R. Klenk , Joshua Wallin , Peter M. Martin
IPC分类号： A61F2/00
CPC分类号： A61B17/00234 , A61B17/0293 , A61B17/3468 , A61B2017/00243 , A61B2017/308 , A61F2/2481 , A61F2002/2484
摘要： An apparatus for delivering a medical device onto a heart includes a housing within which is releasably disposed the medical device. The housing in one embodiment comprises inner and outer deflectors between which is delivered the medical device. Both deflectors are self-expanding. A deflector compression sheath is slidable longitudinally over the housing to a delivery position at which it moves the deflectors to a collapsed configuration. The compression sheath is retracted to a deployment position to permit the deflectors to deploy by self-expanding to their larger diameters. The outer deflector has an expanded diameter sufficient to engage the inner surface of the pericardium to hold it away from the delivery site while the second deflector guides the medical device into position over the heart while protecting the heart. In another embodiment, the housing includes only an outer deflector. The apparatus also functions as an introducer when the compression sheath is moved to the delivery or “introducer” position at which configuration, the apparatus functions as an introducer.
摘要翻译：用于将医疗装置递送到心脏上的装置包括壳体，其中可释放地设置在医疗装置上。一个实施例中的壳体包括内部和外部偏转器，在其间输送医疗装置。两个导流板都是自扩展的。偏转器压缩护套可以在壳体上纵向滑动到输送位置，在该输送位置，偏转器将偏转器移动到收缩构型。压缩护套缩回到展开位置，以允许偏转器通过自扩张而展开成较大的直径。外导流器具有足以接合心包内表面的扩张直径以将其远离输送部位，而第二导流器将医疗装置引导到心脏上方的位置，同时保护心脏。在另一个实施例中，壳体仅包括外部偏转器。当压缩护套移动到输送或“导引器”位置时，该装置还用作导引器，在该位置处，该装置用作导引器。

3. 发明申请

US20130012982A1 IMPLANT RETRIEVAL SYSTEM 审中-公开
公开(公告)号：US20130012982A1
公开(公告)日：2013-01-10
申请号：US13617308
申请日：2012-09-14
申请人： Alexander K. Khairkhahan , Andrew G.C. Frazier , Alan R. Klenk , Marc S. Kreidler , Stewart M. Kume , Darrell H. Ogi , Chad C. Roue , Erik J. van der Burg
发明人： Alexander K. Khairkhahan , Andrew G.C. Frazier , Alan R. Klenk , Marc S. Kreidler , Stewart M. Kume , Darrell H. Ogi , Chad C. Roue , Erik J. van der Burg
IPC分类号： A61F2/01
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B17/122 , A61B2017/00243 , A61B2017/00557 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00619 , A61B2017/00623 , A61B2017/081 , A61B2017/1205 , A61B2017/12095 , A61F2/01 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0071 , A61F2230/008 , A61M25/10 , A61M2025/1054 , A61M2210/125
摘要： Disclosed is an adjustable occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed.

4. 发明申请

US20120035643A1 METHOD OF IMPLANTING AN ADJUSTABLE OCCLUSION DEVICE 有权
标题翻译：将可调节的装置装入的方法
公开(公告)号：US20120035643A1
公开(公告)日：2012-02-09
申请号：US13274380
申请日：2011-10-17
申请人： Alexander K. Khairkhahan , Andrew G.C. Frazier , Alan R. Klenk , Marc S. Kreidler , Stewart M. Kume , Darrell H. Ogi , Chad C. Roue , Erik J. van der Burg , Dino DeCicco , Michael D. Lesh
发明人： Alexander K. Khairkhahan , Andrew G.C. Frazier , Alan R. Klenk , Marc S. Kreidler , Stewart M. Kume , Darrell H. Ogi , Chad C. Roue , Erik J. van der Burg , Dino DeCicco , Michael D. Lesh
IPC分类号： A61M29/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B17/122 , A61B2017/00243 , A61B2017/00557 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00619 , A61B2017/00623 , A61B2017/081 , A61B2017/1205 , A61B2017/12095 , A61F2/01 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0071 , A61F2230/008 , A61M25/10 , A61M2025/1054 , A61M2210/125
摘要： Disclosed is an adjustable occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed.
摘要翻译：公开了一种用于体腔内的可调闭塞装置，例如左心耳。闭塞装置可移除地由展开导管携带。该装置可以被放大或缩小以便于最佳的放置或移除。还公开了方法。

5. 发明申请

US20100234885A1 PATENT FORAMEN OVALE CLOSURE SYSTEM 审中-公开
标题翻译：专利OVAM封闭系统
公开(公告)号：US20100234885A1
公开(公告)日：2010-09-16
申请号：US12791410
申请日：2010-06-01
申请人： Andrew G.C. Frazier , Alan R. Klenk , Alexander K. Khairkhahan , Chad C. Roue , Erik J. van der Burg
发明人： Andrew G.C. Frazier , Alan R. Klenk , Alexander K. Khairkhahan , Chad C. Roue , Erik J. van der Burg
IPC分类号： A61B17/08
CPC分类号： A61B17/12122 , A61B17/00491 , A61B17/0057 , A61B17/064 , A61B17/12113 , A61B17/12172 , A61B17/1219 , A61B2017/00243 , A61B2017/00557 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/0649
摘要： A patent foramen ovale closure device, method of delivering and a delivery system are provided. The device may include a closure device releasably connectable to an actuator. The device may include a proximal segment, an intermediate segment and a distal segment. When delivered, the proximal segment and intermediate segment form a first clip-shaped portion sized and configured to be positioned over a septum secundum of the patent foramen ovale, and the intermediate segment and distal segment form a second clip-shaped portion sized and configured to be positioned over a septum primum of the patent foramen ovale.
摘要翻译：提供了一种卵孔闭合装置，输送方法和输送系统。该装置可以包括可释放地连接到致动器的闭合装置。该装置可以包括近端段，中间段和远端段。当输送时，近端段和中间段形成第一夹形部分，其大小和构造成定位在卵孔卵孔的隔膜的隔膜上方，并且中间段和远端段形成第二夹形部分，其尺寸和构造为位于卵圆孔卵巢的隔膜上。

6. 发明授权

US09131849B2 Method and apparatus for accessing the left atrial appendage 有权
公开(公告)号：US09131849B2
公开(公告)日：2015-09-15
申请号：US11228988
申请日：2005-09-16
申请人： Alexander K. Khairkhahan , Andrew G. C. Frazier , Alan R. Klenk , Marc S. Kreidler , Stewart M. Kume , Darrell H. Ogi , Chad C. Roue , Erik J. van der Burg
发明人： Alexander K. Khairkhahan , Andrew G. C. Frazier , Alan R. Klenk , Marc S. Kreidler , Stewart M. Kume , Darrell H. Ogi , Chad C. Roue , Erik J. van der Burg
IPC分类号： A61B5/00 , A61M25/00 , A61B17/3203 , A61B17/3207 , A61B17/34 , A61B17/32 , A61B17/00 , A61B18/00
CPC分类号： A61B17/3423 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B17/320016 , A61B17/32037 , A61B17/320725 , A61B17/32075 , A61B17/3478 , A61B2017/00243 , A61B2017/00247 , A61B2017/00398 , A61B2017/00783 , A61B2017/3425 , A61B2018/00392 , A61M25/0084
摘要： Disclosed is an apparatus for facilitating access to the left atrium, and specifically the left atrial appendage. The apparatus may comprise a sheath with first and second curved sections that facilitate location of the fossa ovalis and left atrial appendage. The apparatus may further comprise tissue piercing and dilating structures. Methods are also disclosed.

7. 发明授权

US08323309B2 Adjustable left atrial appendage implant 有权
标题翻译：可调左心耳植入物
公开(公告)号：US08323309B2
公开(公告)日：2012-12-04
申请号：US10441468
申请日：2003-05-19
申请人： Alexander K. Khairkhahan , Andrew G. C. Frazier , Alan R. Klenk , Marc S. Kreidler , Stewart M. Kume , Darrell H. Ogi , Chad C. Roue , Erik J. van der Burg
发明人： Alexander K. Khairkhahan , Andrew G. C. Frazier , Alan R. Klenk , Marc S. Kreidler , Stewart M. Kume , Darrell H. Ogi , Chad C. Roue , Erik J. van der Burg
IPC分类号： A61M29/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B17/122 , A61B2017/00243 , A61B2017/00557 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00619 , A61B2017/00623 , A61B2017/081 , A61B2017/1205 , A61B2017/12095 , A61F2/01 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0071 , A61F2230/008 , A61M25/10 , A61M2025/1054 , A61M2210/125
摘要： Disclosed is an adjustable occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed.
摘要翻译：公开了一种用于体腔内的可调闭塞装置，例如左心耳。闭塞装置可移除地由展开导管携带。该装置可以被放大或缩小以便于最佳的放置或移除。还公开了方法。

8. 发明授权

US07780700B2 Patent foramen ovale closure system 有权
标题翻译：卵圆孔闭合系统
公开(公告)号：US07780700B2
公开(公告)日：2010-08-24
申请号：US10771845
申请日：2004-02-04
申请人： Andrew G. C. Frazier , Alan R. Klenk , Alexander K. Khairkhahan , Chad C. Roue , Erik J. van der Burg
发明人： Andrew G. C. Frazier , Alan R. Klenk , Alexander K. Khairkhahan , Chad C. Roue , Erik J. van der Burg
IPC分类号： A61B17/08
CPC分类号： A61B17/12122 , A61B17/00491 , A61B17/0057 , A61B17/064 , A61B17/12113 , A61B17/12172 , A61B17/1219 , A61B2017/00243 , A61B2017/00557 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/0649
摘要： A patent foramen ovale closure device, method of delivering and a delivery system are provided. The device may include a closure device releasably connectable to an actuator. The device may include a proximal segment, an intermediate segment and a distal segment. When delivered, the proximal segment and intermediate segment form a first clip-shaped portion sized and configured to be positioned over a septum secundum of the patent foramen ovale, and the intermediate segment and distal segment form a second clip-shaped portion sized and configured to be positioned over a septum primum of the patent foramen ovale.
摘要翻译：提供了一种卵孔闭合装置，输送方法和输送系统。该装置可以包括可释放地连接到致动器的闭合装置。该装置可以包括近端段，中间段和远端段。当输送时，近端段和中间段形成第一夹形部分，其大小和构造成定位在卵孔卵孔的隔膜的隔膜上方，并且中间段和远端段形成第二夹形部分，其尺寸和构造为位于卵圆孔卵巢的隔膜上。

9. 发明授权

US5925061A Low profile vascular stent 失效
标题翻译：低调血管支架
公开(公告)号：US5925061A
公开(公告)日：1999-07-20
申请号：US782114
申请日：1997-01-13
申请人： Darrell H. Ogi , Lilip Lau , Alan R. Klenk
发明人： Darrell H. Ogi , Lilip Lau , Alan R. Klenk
IPC分类号： A61F2/84 , A61F2/06 , A61F2/90 , A61M29/00
CPC分类号： A61F2/91 , A61F2/915 , A61F2/88 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2230/0054
摘要： A low-profile, self-expanding vascular stent which is preferably cut from a thin tubing. The stent includes helical windings in a single helix, which are joined by bridges for longitudinal and radial strengthening.
摘要翻译：优选从薄管切割的低调自扩张血管支架。支架包括在单个螺旋中的螺旋绕组，其通过用于纵向和径向强化的桥连接。

10. 发明授权

US08663273B2 Method of implanting an adjustable occlusion device 有权
标题翻译：植入可调闭塞装置的方法
公开(公告)号：US08663273B2
公开(公告)日：2014-03-04
申请号：US13274380
申请日：2011-10-17
申请人： Alexander K. Khairkhahan , Andrew G. C. Frazier , Alan R. Klenk , Marc S. Kreidler , Stewart M. Kume , Darrell H. Ogi , Chad C. Roue , Erik J. van der Burg , Dino DeCicco , Michael D. Lesh
发明人： Alexander K. Khairkhahan , Andrew G. C. Frazier , Alan R. Klenk , Marc S. Kreidler , Stewart M. Kume , Darrell H. Ogi , Chad C. Roue , Erik J. van der Burg , Dino DeCicco , Michael D. Lesh
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B17/122 , A61B2017/00243 , A61B2017/00557 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00619 , A61B2017/00623 , A61B2017/081 , A61B2017/1205 , A61B2017/12095 , A61F2/01 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0071 , A61F2230/008 , A61M25/10 , A61M2025/1054 , A61M2210/125
摘要： Disclosed is an adjustable occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed.
摘要翻译：公开了一种用于体腔内的可调闭塞装置，例如左心耳。闭塞装置可移除地由展开导管携带。该装置可以被放大或缩小以便于最佳的放置或移除。还公开了方法。

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