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1. 发明授权

US4477578A Method and apparatus for performing assays 失效
标题翻译：用于进行测定的方法和装置
公开(公告)号：US4477578A
公开(公告)日：1984-10-16
申请号：US354848
申请日：1982-03-04
申请人： Laughton E. Miles , Arthur H. Rogers, Jr. , Charles H. Rogers
发明人： Laughton E. Miles , Arthur H. Rogers, Jr. , Charles H. Rogers
IPC分类号： G01N1/38 , G01N33/483 , G01N33/53 , G01N33/543 , G01N33/58 , G01N35/00 , G01N35/10 , G01N33/54 , G01N33/56 , G01N35/04 , G01N35/06
CPC分类号： G01N35/1065 , G01N1/38 , G01N33/5302 , G01N33/54366 , G01N35/00 , G01N2035/00544 , G01N2035/1055 , G01N35/1079 , Y10S436/807 , Y10S436/808 , Y10S436/81 , Y10S436/82 , Y10T436/113332
摘要： Method and apparatus are provided for carrying out multiple simultaneous transfers of fluid. The method and apparatus are particularly directed toward immunoassays wherein immunologically active compounds, such as antigens and haptens, are detected through their associated antibodies. The device relies on the ability to transfer fluids, such as biological samples and reagents, between a reservoir and an associated receptacle. By providing a receptacle having a port at its lower end and which is otherwise hermetically sealed, such fluid transfer can be effected by immersing the port beneath the surface of the fluid in the reservoir and manipulating the pressure on the remaining surface area outside the port. The transfer of biological fluids at positive pressure provides enhanced fluids flow characteristics, particularly reduction or elimination of the tendency of these fluids to froth or bubble. Moreover, since the fluids can easily be manipulated, they can be agitated to speed up the reaction and reduce the overall reaction time and can be transferred from the reaction zone to allow interim measurements of the extent of reaction to provide for a rate mode assay. The method and apparatus also find use in preparing solid phase reagents for use in assay systems, as well as a highly accurate pipetting system in analytic applications not limited to immunoassays.
摘要翻译：提供了用于执行多次同时传送流体的方法和装置。该方法和装置特别针对免疫测定，其中通过其相关抗体检测免疫活性化合物，例如抗原和半抗原。该装置依赖于在储存器和相关容器之间传送流体（例如生物样品和试剂）的能力。通过提供在其下端具有端口并且以其它方式密封的插座，可以通过将端口在流体表面下方浸入储存器中并且操纵在端口外部的剩余表面区域上的压力来实现这种流体转移。生物流体在正压下的转移提供增强的流体流动特性，特别是减少或消除这些流体发泡或起泡的倾向。此外，由于可以容易地操纵流体，因此可以搅拌它们以加速反应并减少总反应时间，并且可以从反应区转移以允许临时测量反应程度以提供速率模式测定。该方法和装置还可用于制备用于测定系统的固相试剂，以及用于不限于免疫测定的分析应用中的高精度移液系统。

2. 发明申请

US20140209660A1 DELIVERING BIOABSORBABLE FASTENERS 有权
标题翻译：交付生物可靠的紧固件
公开(公告)号：US20140209660A1
公开(公告)日：2014-07-31
申请号：US13755540
申请日：2013-01-31
申请人： Charles H. Rogers , Eduard U. Milea
发明人： Charles H. Rogers , Eduard U. Milea
IPC分类号： A61B17/068
CPC分类号： A61B17/068 , A61B17/0401 , A61B17/0682 , A61B2017/0409 , A61B2017/0412 , A61B2017/0416 , A61B2017/0419 , A61B2017/0427 , A61B2017/0445 , A61B2017/0464 , A61B2017/07271
摘要： An apparatus for delivering bioabsorbable fasteners of the type having two cannulated legs to secure the two sides of an incision in tissue comprises a housing containing a magazine with one or more fasteners positioned on a reciprocally movable fastener support. Needle guide tubes and the legs of the front-most fastener are in slidable contact with at least one alignment surface configured to axially align them. An actuator is operated by a user to move two needles within the needle guide tubes to insert each needle into a cannulated leg. A timing lever acts on the fastener support in concert with the actuator movement to remove support of the front-most fastener after the needles are inserted. The needle guide tubes transfer force to the fastener, to push it out of the magazine and along a path through the center of a bifurcated foot, to insert it into the tissue.
摘要翻译：一种用于输送具有两个插管腿的生物可吸收紧固件的装置，用于将切口的两侧固定在组织中，包括容纳具有定位在可往复运动的紧固件支撑件上的一个或多个紧固件的弹匣的壳体。针引导管和最前面的紧固件的腿与至少一个配置成轴向对准它们的对准表面滑动接触。致动器由用户操作以移动针导管内的两个针，以将每个针插入插管腿。定时杠杆与致动器运动一致地作用在紧固件支架上，以在插针之后移除最前面的紧固件的支撑。针导管将力传递到紧固件，将其推出盒子并沿着通过分叉脚的中心的路径将其插入组织。

3. 发明申请

US20090307826A1 Mounting system for accessories on a safety helmet 有权
标题翻译：安全头盔附件安装系统
公开(公告)号：US20090307826A1
公开(公告)日：2009-12-17
申请号：US11350591
申请日：2006-02-09
申请人： David C. Rogers , Charles H. Rogers , Darwin Keith-Lucas
发明人： David C. Rogers , Charles H. Rogers , Darwin Keith-Lucas
IPC分类号： A42B1/24
CPC分类号： A42B3/04
摘要： Embodiments of a fixture secured, securable to, or integral with the outer shell of a helmet of the type that has a bulge or protrusion on a side thereof to facilitate convenient positional adjustment, attachment and removal of multiple accessories include a fixture for securely receiving an accessory, wherein the fixture comprises a rail for slidably and adjustable receiving a plurality of accessories thereon.
摘要翻译：具有固定，固定或与外壳一体的固定装置的实施例，其具有在其一侧上具有凸起或突起的类型的外壳，以便于方便的位置调整，附接和移除多个附件包括用于牢固地接收附件，其中所述固定件包括用于在其上可滑动地且可调节地接收多个附件的导轨。

4. 发明授权

US06235479B1 Methods and devices for performing analysis of a nucleic acid sample 有权
公开(公告)号：US06235479B1
公开(公告)日：2001-05-22
申请号：US09291566
申请日：1999-04-13
申请人： Charles H. Rogers
发明人： Charles H. Rogers
IPC分类号： C12Q168
CPC分类号： G01N35/00584 , G01N35/00603 , G05B2219/2656
摘要： An automated instrument and method for nucleic acid analysis is provided. The automated instrument is an integrated system including a sample processing station, a first reaction module, a second reaction module, a detection module and a control module for performing homogenous screening of broad specificity and multi-detection reactions on a nucleic acid test sample. The nucleic acid analysis performed in the instrument includes the steps of conducting a first test reaction using a low detection format, and if necessary, a selected second test reaction using a high detection format, detecting signals generated from the test reactions and processing signal data in a control module.

5. 发明授权

US5776608A Process for making electrically conductive fibers 失效
标题翻译：制造导电纤维的方法
公开(公告)号：US5776608A
公开(公告)日：1998-07-07
申请号：US870741
申请日：1997-06-06
申请人： Pravin P. Asher , Robert L. Lilly , Grover L. Davenport, Jr. , Robert K. Hyatt , Charles H. Rogers
发明人： Pravin P. Asher , Robert L. Lilly , Grover L. Davenport, Jr. , Robert K. Hyatt , Charles H. Rogers
IPC分类号： D01F1/09 , D01F8/04 , D01F8/14 , D02G3/00
CPC分类号： D01F1/09 , D01F8/04 , D01F8/14 , Y10T428/2924 , Y10T428/2929 , Y10T428/2931
摘要： Electrically conductive thermoplastic fibers are made by spinning a fiber having an electrically conductive sheath of thermoplastic polymer formulated with carbon black and a nonconductive core from the thermoplastic polymer; quenching the fiber after said spinning to a temperature below the melting point of the thermoplastic; drawing the quenched fiber at a draw ratio between about 2.0 and about 3.2; and, after drawing, relaxing the fiber at a temperature below the melting point of the thermoplastic but above its glass transition.
摘要翻译：导电热塑性纤维通过将具有由炭黑和非导电芯配制的热塑性聚合物的导电护套的纤维从热塑性聚合物中纺丝而制成; 在所述纺丝之后将纤维淬火至低于热塑性塑料的熔点的温度; 以约2.0至约3.2的拉伸比拉伸淬火的纤维; 并且在拉伸后，在低于热塑性塑料的熔点但高于其玻璃化转变温度的温度下松弛纤维。

6. 发明授权

US5698148A Process for making electrically conductive fibers 失效
标题翻译：制造导电纤维的方法
公开(公告)号：US5698148A
公开(公告)日：1997-12-16
申请号：US686854
申请日：1996-07-26
申请人： Pravin P. Asher , Robert L. Lilly , Grover L. Davenport, Jr. , Robert K. Hyatt , Charles H. Rogers
发明人： Pravin P. Asher , Robert L. Lilly , Grover L. Davenport, Jr. , Robert K. Hyatt , Charles H. Rogers
IPC分类号： D01F1/09 , D01F8/04 , D01F8/14
CPC分类号： D01F1/09 , D01F8/04 , D01F8/14 , Y10T428/2924 , Y10T428/2929 , Y10T428/2931
摘要： Electrically conductive thermoplastic fibers are made by spinning a fiber having an electrically conductive sheath of thermoplastic polymer formulated with carbon black and a non-conductive core from the thermoplastic polymer; quenching the fiber after said spinning to a temperature below the melting point of the thermoplastic; drawing the quenched fiber at a draw ratio between about 2.0 and about 3.2; and, after drawing, relaxing the fiber at a temperature below the melting point of the thermoplastic but above its glass transition.
摘要翻译：导电热塑性纤维通过将具有由炭黑和非导电芯配制的热塑性聚合物的导电护套的纤维从热塑性聚合物中纺丝而制成; 在所述纺丝之后将纤维淬火至低于热塑性塑料的熔点的温度; 以约2.0至约3.2的拉伸比拉伸淬火的纤维; 并且在拉伸后，在低于热塑性塑料的熔点但高于其玻璃化转变温度的温度下松弛纤维。

7. 发明授权

US09232943B2 Delivering bioabsorbable fasteners 有权
标题翻译：提供生物可吸收的紧固件
公开(公告)号：US09232943B2
公开(公告)日：2016-01-12
申请号：US13755540
申请日：2013-01-31
申请人： Charles H. Rogers , Eduard U. Milea
发明人： Charles H. Rogers , Eduard U. Milea
IPC分类号： A61B17/068 , A61B17/064 , A61B17/08 , A61B17/04 , A61B17/072
CPC分类号： A61B17/068 , A61B17/0401 , A61B17/0682 , A61B2017/0409 , A61B2017/0412 , A61B2017/0416 , A61B2017/0419 , A61B2017/0427 , A61B2017/0445 , A61B2017/0464 , A61B2017/07271
摘要： An apparatus for delivering bioabsorbable fasteners of the type having two cannulated legs to secure the two sides of an incision in tissue comprises a housing containing a magazine with one or more fasteners positioned on a reciprocally movable fastener support. Needle guide tubes and the legs of the front-most fastener are in slidable contact with at least one alignment surface configured to axially align them. An actuator is operated by a user to move two needles within the needle guide tubes to insert each needle into a cannulated leg. A timing lever acts on the fastener support in concert with the actuator movement to remove support of the front-most fastener after the needles are inserted. The needle guide tubes transfer force to the fastener, to push it out of the magazine and along a path through the center of a bifurcated foot, to insert it into the tissue.
摘要翻译：一种用于输送具有两个插管腿的生物可吸收紧固件的装置，用于将切口的两侧固定在组织中，包括容纳具有定位在可往复运动的紧固件支撑件上的一个或多个紧固件的弹匣的壳体。针引导管和最前面的紧固件的腿与至少一个配置成轴向对准它们的对准表面滑动接触。致动器由用户操作以移动针导管内的两个针，以将每个针插入插管腿。定时杠杆与致动器运动一致地作用在紧固件支架上，以在插针之后移除最前面的紧固件的支撑。针导管将力传递到紧固件，将其推出盒子并沿着通过分叉脚的中心的路径将其插入组织。

8. 发明申请

US20120325889A1 TISSUE FASTENERS AND RELATED INSERTION DEVICES, MECHANISMS, AND METHODS 审中-公开
标题翻译：组织紧固件和相关插入装置，机构和方法
公开(公告)号：US20120325889A1
公开(公告)日：2012-12-27
申请号：US13604190
申请日：2012-09-05
申请人： Kenneth S. Danielson , Charles H. Rogers , Peter L. Stokes , Edward R. Hall
发明人： Kenneth S. Danielson , Charles H. Rogers , Peter L. Stokes , Edward R. Hall
IPC分类号： A61B17/068
CPC分类号： A61B17/064 , A61B17/0682 , A61B17/08 , A61B2017/00004 , A61B2017/0641 , A61B2017/081
摘要： A mechanism for deploying a fastener into skin tissue comprises a first foot, a second foot, and an insertion device. The first foot is configured to contact an external surface of the skin tissue on one side of an incision or wound. The second foot is configured to contact the external skin surface on the other side of the incision/wound. The first and second feet are spaced apart by a gap, and each is configured to allow the skin tissue from one side of the incision or wound to be retracted thereover at an acute angle to expose an inner surface of each of the sides of the incision or wound. The insertion device releasably holds the fastener and is movable to deploy the fastener into the exposed inner surfaces from above and generally perpendicular to the external skin surface.
摘要翻译：用于将紧固件部署到皮肤组织中的机构包括第一脚，第二脚和插入装置。第一脚构造成接触切口或伤口一侧的皮肤组织的外表面。第二脚构造成接触切口/伤口另一侧的外部皮肤表面。第一和第二脚间隔开间隔，并且每个构造成允许来自切口或伤口的一侧的皮肤组织以锐角收缩，以暴露切口的每一侧的内表面或伤口。插入装置可释放地保持紧固件并且可移动以将紧固件从上方并大体上垂直于外部皮肤表面部署到暴露的内表面中。

9. 外观设计

USD566903S1 Helmet 有权
公开(公告)号：USD566903S1
公开(公告)日：2008-04-15
申请号：US29252009
申请日：2006-01-17
申请人： David Rogers , Charles H. Rogers , Peter Stokes
设计人： David Rogers , Charles H. Rogers , Peter Stokes

10. 发明授权

US5614142A Process for spinning thermoplastic fibers on a grid spinning system 失效
标题翻译：在网格纺纱系统中纺丝热塑性纤维的工艺
公开(公告)号：US5614142A
公开(公告)日：1997-03-25
申请号：US559863
申请日：1995-11-20
申请人： Robert L. Lilly , Robert H. Blackwell , Charles H. Rogers , Zachary G. Shoaf
发明人： Robert L. Lilly , Robert H. Blackwell , Charles H. Rogers , Zachary G. Shoaf
IPC分类号： D01D1/06 , D01F1/02 , D01F1/10
CPC分类号： D01D1/065
摘要： Fibers are made from thermoplastic polymers by supplying solid particles of the thermoplastic to a melting grid; heating the melting grid to a temperature sufficient to melt the thermoplastic; melting the thermoplastic particles on the heated melting grid such that the melted thermoplastic flows through the grid and is collected in a collecting chamber located beneath the melting grid; injecting into the collecting chamber below the melting grid an additive present in a non-aqueous carrier which carrier comprises organic rosin materials and a surfactant; without actuated mechanical stirring, forming a substantially homogeneous mixture from the injected additive; and extruding fibers from the substantially homogeneous mixture.
摘要翻译：纤维由热塑性聚合物制成，通过将热塑性塑料的固体颗粒提供给熔化网; 将熔化炉加热到足以熔化热塑性塑料的温度; 使加热的熔化格栅上的热塑性颗粒熔化，使得熔融的热塑性塑料流过网格并且被收集在位于熔融格栅下方的收集室中; 在熔融网格下方的收集室中注入存在于非水载体中的添加剂，载体包含有机松香材料和表面活性剂; 没有致动机械搅拌，从注入的添加剂形成基本均匀的混合物; 并从基本均匀的混合物挤出纤维。

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