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1. 发明授权

US07126003B2 Method for producing 2-azetidinone derivative 有权
标题翻译： 2-氮杂环丁酮衍生物的制备方法
公开(公告)号：US07126003B2
公开(公告)日：2006-10-24
申请号：US10469918
申请日：2002-03-04
申请人： Kouji Sato , Tsutomu Yagi , Yutaka Kitagawa , Shigeru Ichikawa , Akihiro Imura
发明人： Kouji Sato , Tsutomu Yagi , Yutaka Kitagawa , Shigeru Ichikawa , Akihiro Imura
IPC分类号： C07D401/04 , C07D205/04
CPC分类号： C07D401/04 , C07D205/08 , C12P17/10 , C12P41/003
摘要： A process for producing a compound represented by the following formula (II) which comprises treating a compound represented by the following formula (I) (wherein R1, R2 and R3 represent each a specific substituent) with an enzyme capable of asymmetrically hydrolyzing an ester and the novel compound (II). The process of the present invention makes it possible to easily obtain an optically active 2-azetidinone derivative in a large amount at a low cost
摘要翻译：一种制备由下式（II）表示的化合物的方法，其包括将下式（I）表示的化合物（其中R 1，R 2，R 2和R 2）具有能够不对称地水解酯和新化合物（II）的酶代表每个特定取代基）。本发明的方法使得可以以低成本容易地获得大量光学活性的2-氮杂环丁酮衍生物

2. 发明申请

US20050027119A1 Process for producing benzoxazine derivative and production intermediate thereof 有权
标题翻译：制备苯并恶嗪衍生物的方法及其制备中间体
公开(公告)号：US20050027119A1
公开(公告)日：2005-02-03
申请号：US10922832
申请日：2004-08-23
申请人： Kouji Sato , Yoshihiro Takayanagi , Katsuhiko Okano , Keiji Nakayama , Akihiro Imura , Mikihiro Itoh , Tsutomu Yagi , Yukinari Kobayashi , Tomoyuki Nagai
发明人： Kouji Sato , Yoshihiro Takayanagi , Katsuhiko Okano , Keiji Nakayama , Akihiro Imura , Mikihiro Itoh , Tsutomu Yagi , Yukinari Kobayashi , Tomoyuki Nagai
IPC分类号： A61P31/04 , C07C213/00 , C07C215/16 , C07C227/08 , C07C227/34 , C07C227/36 , C07C229/18 , C07C229/30 , C07D265/36 , C07D498/06 , C12P13/00 , C07D498/02
CPC分类号： C07D498/06 , C07B57/00 , C07B2200/07 , C07C213/00 , C07C227/08 , C07C227/34 , C07C227/36 , C07C229/18 , C07C229/30 , C07D265/36 , C12P13/001 , C12P13/02 , C12P13/04 , C12P41/005 , Y02P20/55 , C07C215/16
摘要： A processes which is industrially advantageous in producing antibacterial agents. An industrially advantageous process for producing an intermediate useful in producing antibactrial agents is provided by producing compound (VI-a) in accordance with the following reaction schema. A process for producing the compound represented by the above formulae and production intermediates thereof.
摘要翻译：一种工业上有利于生产抗菌剂的方法。通过根据以下反应方案制备化合物（VI-a），提供了用于制备可用于生产抗菌剂的中间体的工业上有利的方法。一种制备由上式表示的化合物及其制备中间体的方法。

3. 发明授权

US07217560B2 Process for preparation of optically active propoxyaniline derivatives 失效
标题翻译：光学活性苯氧基苯胺衍生物的制备方法
公开(公告)号：US07217560B2
公开(公告)日：2007-05-15
申请号：US10469827
申请日：2002-03-06
申请人： Kouji Sato , Tsutomu Yagi , Kazuo Kubota , Akihiro Imura
发明人： Kouji Sato , Tsutomu Yagi , Kazuo Kubota , Akihiro Imura
IPC分类号： C12P41/00
CPC分类号： C12P13/001 , C07D265/34 , C12P7/62 , C12P13/008 , C12P17/188 , C12P41/005
摘要： Treatment of a lactic acid ester derivative with an enzyme or the like, which has asymmetric ester-hydrolyzing ability, can specifically hydrolyze the ester moiety of an isomer existing as the pair to the racemic derivative. Use of the compound obtained by this hydrolysis makes it possible to produce an optically active propoxyaniline derivative by a shorter process than the conventional art
摘要翻译：具有不对称酯水解能力的酶等的乳酸酯衍生物的处理可以将存在的异构体的酯部分特异性水解成外消旋衍生物。通过该水解获得的化合物的使用可以通过比常规技术更短的方法制备光学活性的丙氧基苯胺衍生物

4. 发明授权

US06872823B1 Process for producing benzoxazine derivative and production intermediate thereof 失效
标题翻译：制备苯并恶嗪衍生物的方法及其制备中间体
公开(公告)号：US06872823B1
公开(公告)日：2005-03-29
申请号：US10070556
申请日：2000-09-07
申请人： Kouji Sato , Yoshihiro Takayanagi , Katsuhiko Okano , Keiji Nakayama , Akihiro Imura , Mikihiro Itoh , Tsutomu Yagi , Yukinari Kobayashi , Tomoyuki Nagai
发明人： Kouji Sato , Yoshihiro Takayanagi , Katsuhiko Okano , Keiji Nakayama , Akihiro Imura , Mikihiro Itoh , Tsutomu Yagi , Yukinari Kobayashi , Tomoyuki Nagai
IPC分类号： A61P31/04 , C07C213/00 , C07C215/16 , C07C227/08 , C07C227/34 , C07C227/36 , C07C229/18 , C07C229/30 , C07D265/36 , C07D498/06 , C12P13/00 , A61K31/5365
CPC分类号： C07D498/06 , C07B57/00 , C07B2200/07 , C07C213/00 , C07C227/08 , C07C227/34 , C07C227/36 , C07C229/18 , C07C229/30 , C07D265/36 , C12P13/001 , C12P13/02 , C12P13/04 , C12P41/005 , Y02P20/55 , C07C215/16
摘要： Processes for producing antibacterial agents and intermediates useful in producing antibacterial agents are provided and include producing compound (VI-a) in accordance with the following reaction schema, as well as production intermediates thereof.
摘要翻译：提供用于制备抗菌剂的方法和用于生产抗菌剂的中间体，包括根据以下反应方案制备化合物（VI-a）及其生产中间体。

5. 发明申请

US20060014947A1 Process for producing benzoxazine derivative and production intermediate thereof 有权
标题翻译：制备苯并恶嗪衍生物的方法及其制备中间体
公开(公告)号：US20060014947A1
公开(公告)日：2006-01-19
申请号：US11225058
申请日：2005-09-14
申请人： Kouji Sato , Yoshihiro Takayanagi , Katsuhiko Okano , Keiji Nakayama , Akihiro Imura , Mikihiro Itoh , Tsutomu Yagi , Yukinari Kobayashi , Tomoyuki Nagai
发明人： Kouji Sato , Yoshihiro Takayanagi , Katsuhiko Okano , Keiji Nakayama , Akihiro Imura , Mikihiro Itoh , Tsutomu Yagi , Yukinari Kobayashi , Tomoyuki Nagai
IPC分类号： C07D265/36
CPC分类号： C07D498/06 , C07B57/00 , C07B2200/07 , C07C213/00 , C07C227/08 , C07C227/34 , C07C227/36 , C07C229/18 , C07C229/30 , C07D265/36 , C12P13/001 , C12P13/02 , C12P13/04 , C12P41/005 , Y02P20/55 , C07C215/16
摘要： Processes for producing antibacterial agents and intermediates useful in producing antibacterial agents are provided and include producing compound (VI-a) in accordance with the following reaction schema, as well as production intermediates thereof.
摘要翻译：提供用于制备抗菌剂的方法和用于生产抗菌剂的中间体，包括根据以下反应方案制备化合物（VI-a）及其生产中间体。

6. 发明授权

US07189847B2 Process for producing benzoxazine derivative and production intermediate thereof 有权
标题翻译：制备苯并恶嗪衍生物的方法及其制备中间体
公开(公告)号：US07189847B2
公开(公告)日：2007-03-13
申请号：US11225058
申请日：2005-09-14
申请人： Kouji Sato , Yoshihiro Takayanagi , Katsuhiko Okano , Keiji Nakayama , Akihiro Imura , Mikihiro Itoh , Tsutomu Yagi , Yukinari Kobayashi , Tomoyuki Nagai
发明人： Kouji Sato , Yoshihiro Takayanagi , Katsuhiko Okano , Keiji Nakayama , Akihiro Imura , Mikihiro Itoh , Tsutomu Yagi , Yukinari Kobayashi , Tomoyuki Nagai
IPC分类号： C07D265/36 , C07D498/02
CPC分类号： C07D498/06 , C07B57/00 , C07B2200/07 , C07C213/00 , C07C227/08 , C07C227/34 , C07C227/36 , C07C229/18 , C07C229/30 , C07D265/36 , C12P13/001 , C12P13/02 , C12P13/04 , C12P41/005 , Y02P20/55 , C07C215/16
摘要： Processes for producing antibacterial agents and intermediates useful in producing antibacterial agents are provided and include producing compound (VI-a) in accordance with the following reaction schema, as well as production intermediates thereof
摘要翻译：提供了用于制备抗菌剂的方法和用于生产抗菌剂的中间体，包括根据以下反应方案制备化合物（VI-a）及其生产中间体

7. 发明授权

US07087778B2 Process for producing benzoxazine derivative and production intermediate thereof 有权
标题翻译：制备苯并恶嗪衍生物的方法及其制备中间体
公开(公告)号：US07087778B2
公开(公告)日：2006-08-08
申请号：US10922832
申请日：2004-08-23
申请人： Kouji Sato , Yoshihiro Takayanagi , Katsuhiko Okano , Keiji Nakayama , Akihiro Imura , Mikihiro Itoh , Tsutomu Yagi , Yukinari Kobayashi , Tomoyuki Nagai
发明人： Kouji Sato , Yoshihiro Takayanagi , Katsuhiko Okano , Keiji Nakayama , Akihiro Imura , Mikihiro Itoh , Tsutomu Yagi , Yukinari Kobayashi , Tomoyuki Nagai
IPC分类号： C07C229/00 , C07C211/00
CPC分类号： C07D498/06 , C07B57/00 , C07B2200/07 , C07C213/00 , C07C227/08 , C07C227/34 , C07C227/36 , C07C229/18 , C07C229/30 , C07D265/36 , C12P13/001 , C12P13/02 , C12P13/04 , C12P41/005 , Y02P20/55 , C07C215/16
摘要： Processes for producing antibacterial agents and intermediates useful in producing antibacterial agents are provided and include producing compound (VI-a) in accordance with the following reaction schema, as well as production intermediates thereof
摘要翻译：提供了用于制备抗菌剂的方法和用于生产抗菌剂的中间体，包括根据以下反应方案制备化合物（VI-a）及其生产中间体

8. 发明授权

US08441220B2 Control device for electric rotating machine 有权
标题翻译：电动旋转机控制装置
公开(公告)号：US08441220B2
公开(公告)日：2013-05-14
申请号：US13238309
申请日：2011-09-21
申请人： Akihiro Imura
发明人： Akihiro Imura
IPC分类号： H02P21/00
CPC分类号： H02P21/13 , H02P21/0017
摘要： A control device has a predicting unit for predicting a first current flowing through a motor in a next control period, at a predicting time during a predetermined period after a change of switching state in an inverter by using a current detected before the change and for predicting a second current of a control period later than the next control period by one control period by using the predicted first current, a determining unit for determining a next operating state of the inverter by using the predicted second current and an instructed value so as to reduce a change of switching state in the change of the operating state, and a control unit for controlling the inverter to be set in the determined operating state in the next control period and controlling the current of the motor depending on the operating state of the inverter.
摘要翻译：控制装置具有预测单元，用于通过使用在变化之前检测到的电流来预测逆变器中的开关状态改变之后的预定时间段中的预测时间来预测下一个控制周期中流过电动机的第一电流，并且用于预测通过使用预测的第一电流，比下一个控制周期晚一个控制周期的控制周期的第二电流;确定单元，用于通过使用预测的第二电流和指示值来确定逆变器的下一个操作状态，以便减少改变操作状态的切换状态的变化，以及控制单元，用于控制在下一个控制周期内将所述变频器设定在所述确定的运行状态，并且根据所述逆变器的运行状态来控制所述电动机的电流。

9. 发明授权

US07514896B2 Method of estimating magnetic pole position in synchronous motor 有权
标题翻译：同步电机磁极位置估算方法
公开(公告)号：US07514896B2
公开(公告)日：2009-04-07
申请号：US11505466
申请日：2006-08-17
申请人： Akihiro Imura , Yasuaki Aoki
发明人： Akihiro Imura , Yasuaki Aoki
IPC分类号： H02P1/46
CPC分类号： H02P6/182 , H02P21/18 , H02P2207/05
摘要： In a method of estimating a magnetic pole position in a synchronous motor, an alternating current voltage having α- and β-axes components in an αβ coordinates system representing a two-phase alternating current coordinates system is applied to the motor, and α- and β-axes components of an alternating current are detected from the motor. A wave height of the alternating current changing with time is approximated to a wave height not depending on time, so that a differentiated value of the wave height with respect to time is substantially set at zero. An induced voltage of the motor is calculated from the components of the alternating current voltage and the components of the alternating current. The magnetic pole position is estimated from the induced voltage.
摘要翻译：在估计同步电动机中的磁极位置的方法中，在表示两相交流电坐标系的字母表坐标系中具有α轴和β轴分量的交流电压被施加到电机上，而α 从电机检测交流电流的β轴分量。随时间变化的交变电流的波高近似于不依赖于时间的波高，使得波高相对于时间的微分值基本上设置为零。电动机的感应电压根据交流电压和交流电流的分量计算。从感应电压估计磁极位置。

10. 发明授权

US07456302B2 Method for producing pentacyclic taxans 有权
标题翻译：五环类紫杉醇的生产方法
公开(公告)号：US07456302B2
公开(公告)日：2008-11-25
申请号：US11579140
申请日：2005-04-27
申请人： Akihiro Imura , Tatsuya Yamaguchi , Yoshihiro Takayanagi , Seishiro Uchida
发明人： Akihiro Imura , Tatsuya Yamaguchi , Yoshihiro Takayanagi , Seishiro Uchida
IPC分类号： C07D305/14
CPC分类号： C07D213/61 , C07D493/08 , Y02P20/55
摘要： Taxan derivatives are produced efficiently and inexpensively, which are useful as oral-administrable antitumor compounds.A compound of formula (1) (wherein R1 is an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, an aryl group or a heterocyclic group; R2 is a hydroxyl group optionally having a protective group) is processed with an alkali metal permanganate to produce a compound of formula (2), which may be a starting material for oral-administrable antitumor compounds.
摘要翻译：衍生物有效和廉价地生产，其可用作口服给药的抗肿瘤化合物。式（1）的化合物（其中R 1是烷基，烯基，炔基，环烷基，芳基或杂环基; R 2， SUP>是任选具有保护基团的羟基）用碱金属高锰酸盐处理以制备式（2）化合物，其可以是用于口服给药的抗肿瘤化合物的起始材料。

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