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1. 发明申请

US20050101862A1 Ultrasonic bone testing with copolymer transducers 审中-公开
标题翻译：超声波骨骼检测用共聚物换能器
公开(公告)号：US20050101862A1
公开(公告)日：2005-05-12
申请号：US10985865
申请日：2004-11-10
申请人： Kevin Wilson , Hong Wang , Jay Stein , Mitchell Thompson , Klaus Kubierschky , Kyung Park , Dick Cabral , Glen MacGibbon
发明人： Kevin Wilson , Hong Wang , Jay Stein , Mitchell Thompson , Klaus Kubierschky , Kyung Park , Dick Cabral , Glen MacGibbon
IPC分类号： A61B8/00 , A61B8/08
CPC分类号： A61B8/4281 , A61B8/0875 , A61B8/4483
摘要： Ultrasonic bone testing apparatus including a pair of spaced piezoelectric copolymer transducers for transmitting and receiving ultrasonic energy through a bone-containing portion of a human or other animal disposed between the transducers, and circuitry for detecting an electrical signal generated by the receiving transducer in response to reception of ultrasonic energy. The transducers are disks of the copolymer supported by rigid rings spaced inwardly of their peripheries. A method of determining a characteristic of bone in a bone-containing portion of an animal includes positioning a pair of piezoelectric copolymer ultrasonic transducers respectively on opposite sides of, and ultrasonically coupling both transducers to, the animal portion, and transmitting ultrasonic energy through the animal portion including the bone to be tested from one transducer to the other. The animal portion may be a human heel.
摘要翻译：超声波骨测试装置包括一对间隔开的压电共振换能器，用于通过设置在换能器之间的人或其他动物的含骨部分传送和接收超声波能量，以及用于检测由接收换能器响应于接收超声能量。传感器是由其周围间隔开的刚性环支撑的共聚物盘。一种确定动物的含骨头部分中的骨骼特性的方法包括将一对压电共聚物超声波换能器分别定位在动物部分的相对侧并将两个换能器超声波耦合到动物部分上，并将超声波能量通过动物包括从一个换能器到另一个换能器的被测试骨骼的部分。动物部分可以是人的脚跟。

2. 发明授权

US06835178B1 Ultrasonic bone testing with copolymer transducers 失效
标题翻译：超声波骨骼检测用共聚物换能器
公开(公告)号：US06835178B1
公开(公告)日：2004-12-28
申请号：US09595074
申请日：2000-06-16
申请人： Kevin Wilson , Hong Wang , Jay Stein , Mitchell Thompson , Klaus Kubierschky , Kyung Park , Dick Cabral , Glen MacGibbon
发明人： Kevin Wilson , Hong Wang , Jay Stein , Mitchell Thompson , Klaus Kubierschky , Kyung Park , Dick Cabral , Glen MacGibbon
IPC分类号： A61B812
CPC分类号： A61B8/4281 , A61B8/0875 , A61B8/4483
摘要： Ultrasonic bone testing apparatus including a pair of spaced piezoelectric copolymer transducers for transmitting and receiving ultrasonic energy through a bone-containing portion of a human or other animal disposed between the transducers, and circuitry for detecting an electrical signal generated by the receiving transducer in response to reception of ultrasonic energy. The transducers are disks of the copolymer supported by rigid rings spaced inwardly of their peripheries. A method of determining a characteristic of bone in a bone-containing portion of an animal includes positioning a pair of piezoelectric copolymer ultrasonic transducers respectively on opposite sides of, and ultrasonically coupling both transducers to, the animal portion, and transmitting ultrasonic energy through the animal portion including the bone to be tested from one transducer to the other. The animal portion may be a human heel.
摘要翻译：超声波骨测试装置包括一对间隔开的压电共振换能器，用于通过设置在换能器之间的人或其他动物的含骨部分传送和接收超声波能量，以及用于检测由接收换能器响应于接收超声能量。传感器是由其周围间隔开的刚性环支撑的共聚物的盘。一种确定动物的含骨头部分中的骨骼特性的方法包括将一对压电共聚物超声波换能器分别定位在动物部分的相对侧并将两个换能器超声波耦合到动物部分，并且通过动物传送超声波能量包括从一个换能器到另一个换能器的被测试骨骼的部分。动物部分可以是人的脚跟。

3. 发明申请

US20150157288A9 DETECTING AND QUANTIFYING PATIENT MOTION DURING TOMOSYNTHESIS SCANS 有权
标题翻译：在TOMOSYNTHESIS扫描期间检测和定量患者运动
公开(公告)号：US20150157288A9
公开(公告)日：2015-06-11
申请号：US13198352
申请日：2011-08-04
申请人： Baorui Ren , Loren Niklason , Andrew Smith , Zhenxue Jing , Jay Stein
发明人： Baorui Ren , Loren Niklason , Andrew Smith , Zhenxue Jing , Jay Stein
IPC分类号： G06K9/00 , A61B6/02 , A61B5/00 , A61B5/055 , A61B8/13 , A61B8/08 , A61B6/00 , A61B6/03
CPC分类号： A61B6/5264 , A61B5/055 , A61B5/7207 , A61B6/025 , A61B6/035 , A61B6/0414 , A61B6/461 , A61B6/481 , A61B6/502 , A61B6/5223 , A61B8/13 , A61B8/5276 , G06F19/00 , G06T7/246 , G06T2207/10112 , G06T2207/30068
摘要： The effects of patient motion in tomosynthesis scan images are automatically detected and quantified. In at least one embodiment an indication of detection of the effects of patient motion in tomosynthesis scan images is provided shortly after the scan, e.g., before the patient is discharged or before the breast is decompressed. A patient motion score may be calculated as part of motion quantification. The score may be stored for subsequent retrieval. Images may be presented with reference features to help a technician confirm of the effects of motion in images.
摘要翻译：自动检测和量化在体层摄影扫描图像中患者运动的影响。在至少一个实施例中，在扫描之后不久，例如在患者被排出之前或在乳房被减压之前，提供了在层析合成扫描图像中患者运动的影响的检测指示。患者运动评分可以作为运动量化的一部分计算。该分数可以存储用于随后的检索。图像可以呈现参考特征，以帮助技术人员确认图像中运动的影响。

4. 发明授权

US08592772B2 Method of obtaining a molecular breast image 有权
标题翻译：获得分子乳房图像的方法
公开(公告)号：US08592772B2
公开(公告)日：2013-11-26
申请号：US13495556
申请日：2012-06-13
申请人： Jay Stein , Baorui Ren , Andrew P. Smith , Ken Brooks , Zhenxue Jing , Ian Shaw , Kenneth DeFreitas
发明人： Jay Stein , Baorui Ren , Andrew P. Smith , Ken Brooks , Zhenxue Jing , Ian Shaw , Kenneth DeFreitas
IPC分类号： G01T1/166
CPC分类号： A61B6/0414 , A61B6/025 , A61B6/037 , A61B6/06 , A61B6/4021 , A61B6/4291 , A61B6/4411 , A61B6/4441 , A61B6/502 , A61B6/5235
摘要： An integrated tomosynthesis/molecular breast imaging device having improved sensitivity includes tomosynthesis imaging components and molecular breast imaging components. The imaging components may be used individually or in combination to provide a system with improved sensitivity and specificity. Molecular imaging components may be smoothly advanced or withdrawn depending upon the desired imaging mode. The system supports both PET and SPECT imaging and enables SPECT collimation to be modified in accordance with image capture requirements.
摘要翻译：具有改进的灵敏度的综合的断层合成/分子乳房成像装置包括断层成像成像组件和分子乳腺成像组件。成像组件可以单独使用或组合使用以提供具有改善的灵敏度和特异性的系统。根据期望的成像模式，分子成像组件可以顺利地前进或撤回。该系统支持PET和SPECT成像，并且可以根据图像捕获要求修改SPECT准直。

5. 发明申请

US20120250969A1 Integrated Breast X-Ray and Molecular Imaging System and Method 有权
标题翻译：综合乳腺X射线和分子成像系统及方法
公开(公告)号：US20120250969A1
公开(公告)日：2012-10-04
申请号：US13495556
申请日：2012-06-13
申请人： Jay Stein , Baorui Ren , Andrew P. Smith , Ken Brooks , Zhenxue Jing , Ian Shaw , Kenneth F. DeFreitas
发明人： Jay Stein , Baorui Ren , Andrew P. Smith , Ken Brooks , Zhenxue Jing , Ian Shaw , Kenneth F. DeFreitas
IPC分类号： A61B6/04 , G06K9/00
CPC分类号： A61B6/0414 , A61B6/025 , A61B6/037 , A61B6/06 , A61B6/4021 , A61B6/4291 , A61B6/4411 , A61B6/4441 , A61B6/502 , A61B6/5235
摘要： An integrated tomosynthesis/molecular breast imaging device having improved sensitivity includes tomosynthesis imaging components and molecular breast imaging components. The imaging components may be used individually or in combination to provide a system with improved sensitivity and specificity. Molecular imaging components may be smoothly advanced or withdrawn depending upon the desired imaging mode. The system supports both PET and SPECT imaging and enables SPECT collimation to be modified in accordance with image capture requirements.
摘要翻译：具有改进的灵敏度的综合的断层合成/分子乳房成像装置包括断层成像成像组件和分子乳腺成像组件。成像组件可以单独使用或组合使用以提供具有改善的灵敏度和特异性的系统。根据期望的成像模式，分子成像组件可以顺利地前进或撤回。该系统支持PET和SPECT成像，并且可以根据图像捕获要求修改SPECT准直。

6. 发明申请

US20120219111A1 INTEGRATED MULTI-MODE MAMMOGRAPHY/TOMOSYNTHESIS X-RAY SYSTEM AND METHOD 有权
标题翻译：综合多模式人机界面/ TOMOSYNTHESIS X射线系统及方法
公开(公告)号：US20120219111A1
公开(公告)日：2012-08-30
申请号：US13462342
申请日：2012-05-02
申请人： Kenneth Defreitas , Tom Farbizio , Baori Ren , Chris Ruth , Ian Shaw , Andrew Smith , Jay Stein
发明人： Kenneth Defreitas , Tom Farbizio , Baori Ren , Chris Ruth , Ian Shaw , Andrew Smith , Jay Stein
IPC分类号： A61B6/04
CPC分类号： A61B6/4417 , A61B6/025 , A61B6/107 , A61B6/4291 , A61B6/4452 , A61B6/482 , A61B6/502 , G06T2207/30068
摘要： A system for multi-mode breast x-ray imaging which comprises a compression arm assembly for compressing and immobilizing a breast for x-ray imaging, an x-ray tube assembly, and an x-ray image receptor is provided. The system is configured for a plurality of imaging protocols and modes.
摘要翻译：提供了一种用于多模式乳房x射线成像的系统，其包括用于压缩和固定用于X射线成像的乳房的压缩臂组件，X射线管组件和x射线图像接收器。该系统被配置用于多个成像协议和模式。

7. 发明授权

US08217357B2 Integrated breast X-ray and molecular imaging system 有权
标题翻译：综合乳房X线和分子成像系统
公开(公告)号：US08217357B2
公开(公告)日：2012-07-10
申请号：US12422806
申请日：2009-04-13
申请人： Jay Stein , Baorui Ren , Andrew P. Smith , Kenneth F. Brooks , Jing Zhenxue , Ian Shaw , Ken DeFreitas
发明人： Jay Stein , Baorui Ren , Andrew P. Smith , Kenneth F. Brooks , Jing Zhenxue , Ian Shaw , Ken DeFreitas
IPC分类号： G01N23/02
CPC分类号： A61B6/0414 , A61B6/025 , A61B6/037 , A61B6/06 , A61B6/4021 , A61B6/4291 , A61B6/4411 , A61B6/4441 , A61B6/502 , A61B6/5235
摘要： An integrated tomosynthesis/molecular breast imaging device having improved sensitivity includes tomosynthesis imaging components and molecular breast imaging components. The imaging components may be used individually or in combination to provide a system with improved sensitivity and specificity. Molecular imaging components may be smoothly advanced or withdrawn depending upon the desired imaging mode. The system supports both PET and SPECT imaging and enables SPECT collimation to be modified in accordance with image capture requirements.
摘要翻译：具有改进的灵敏度的综合的断层合成/分子乳房成像装置包括断层成像成像组件和分子乳腺成像组件。成像组件可以单独使用或组合使用以提供具有改善的灵敏度和特异性的系统。根据期望的成像模式，分子成像组件可以顺利地前进或撤回。该系统支持PET和SPECT成像，并且可以根据图像捕获要求修改SPECT准直。

8. 发明申请

US20100135558A1 System and Method for Generating a 2D Image from a Tomosynthesis Data Set 有权
标题翻译：从组合数据集生成2D图像的系统和方法
公开(公告)号：US20100135558A1
公开(公告)日：2010-06-03
申请号：US12471981
申请日：2009-05-26
申请人： Chris Ruth , Andrew Smith , Jay Stein
发明人： Chris Ruth , Andrew Smith , Jay Stein
IPC分类号： G06K9/00 , G06F3/00
CPC分类号： A61B6/502 , A61B6/025 , A61B6/461 , A61B6/463 , G06T11/003 , G06T11/006 , G06T11/008 , G06T11/60 , G06T19/00 , G06T19/20 , G06T2207/10081 , G06T2207/10112 , G06T2207/20221 , G06T2207/30068 , G06T2207/30204 , G06T2210/41 , G06T2219/2008
摘要： A 2D mammogram image is synthesized from at least one of tomosynthesis projection images and/or the tomosynthesis reconstructed image data. In a simplest form, the mammogram may be synthesized by selecting one of the tomosynthesis projection images for display as a synthesized mammogram. Other methods of synthesizing a mammogram include re-projecting and filtering projection data and/or reconstructed data. The synthesized mammogram is advantageously displayed together with at least a portion of the reconstructed data to aid in review of the reconstructed data. The present invention thus provides a familiar image which may be used to facilitate review of a tomosynthesis data set.
摘要翻译：从半合成投影图像和/或断层合成重建图像数据中的至少一个合成2D乳房X线照片图像。以最简单的形式，可以通过选择用于显示的合成乳房X光检查图之一的断层合成投影图像来合成乳房X线照片。合成乳房X线照片的其它方法包括重新投影和过滤投影数据和/或重建的数据。合成的乳房X线照片有利地与重构数据的至少一部分一起显示以帮助审查重建的数据。因此，本发明提供了一种熟悉的图像，其可以用于促进对层析合成数据集的检查。

9. 发明授权

US08565374B2 Integrated multi-mode mammography/tomosynthesis x-ray system and method 有权
公开(公告)号：US08565374B2
公开(公告)日：2013-10-22
申请号：US13462342
申请日：2012-05-02
申请人： Kenneth Defreitas , Tom Farbizio , Baori Ren , Chris Ruth , Ian Shaw , Andrew Smith , Jay Stein
发明人： Kenneth Defreitas , Tom Farbizio , Baori Ren , Chris Ruth , Ian Shaw , Andrew Smith , Jay Stein
IPC分类号： G01N23/083 , H05G1/02 , A61B6/04
CPC分类号： A61B6/4417 , A61B6/025 , A61B6/107 , A61B6/4291 , A61B6/4452 , A61B6/482 , A61B6/502 , G06T2207/30068
摘要： A system for multi-mode breast x-ray imaging which comprises a compression arm assembly for compressing and immobilizing a breast for x-ray imaging, an x-ray tube assembly, and an x-ray image receptor is provided. The system is configured for a plurality of imaging protocols and modes.

10. 发明授权

US08565372B2 System and method for low dose tomosynthesis 有权
标题翻译：低剂量层析合成的系统和方法
公开(公告)号：US08565372B2
公开(公告)日：2013-10-22
申请号：US12397013
申请日：2009-03-03
申请人： Jay Stein , Andrew Smith , Zhenzue Jing , Loren Niklason
发明人： Jay Stein , Andrew Smith , Zhenzue Jing , Loren Niklason
IPC分类号： G01N23/083 , H05G1/60 , H05G1/58
CPC分类号： A61B6/025 , A61B6/405 , A61B6/4417 , A61B6/502 , A61B6/5235 , A61B6/5247 , A61B6/542 , A61B8/0825 , G01N23/046
摘要： A breast imaging system leverages the combined strengths of two-dimensional and three-dimensional imaging to provide a breast cancer screening with improved sensitivity, specificity and patient dosing. A tomosynthesis system supports the acquisition of three-dimensional images at a dosage lower than that used to acquire a two-dimensional image. The low-dose three-dimensional image may be used for mass detection, while the two-dimensional image may be used for calcification detection. Obtaining tomosynthesis data at low dose provides a number of advantages in addition to mass detection including the reduction in scan time and wear and tear on the x-ray tube. Such an arrangement provides a breast cancer screening system with high sensitivity and specificity and reduced patient dosing.
摘要翻译：乳房成像系统利用二维和三维成像的综合优势，提供具有改善的敏感性，特异性和患者给药的乳腺癌筛查。断层合成系统支持以比用于获取二维图像的剂量低的剂量获取三维图像。低剂量三维图像可以用于质量检测，而二维图像可以用于钙化检测。以低剂量获得断层合成数据除了质量检测之外还提供了许多优点，包括扫描时间的减少以及X射线管上的磨损和撕裂。这种布置提供了具有高灵敏度和特异性并减少患者给药的乳腺癌筛查系统。

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