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1. 发明申请

US20060111403A1 Cyano anthranilamide insecticides 有权
标题翻译：氰基邻氨基苯甲酰胺杀虫剂
公开(公告)号：US20060111403A1
公开(公告)日：2006-05-25
申请号：US10540966
申请日：2004-01-21
申请人： Kenneth Hughes , George Lahm , Thomas Selby , Thomas Stevenson
发明人： Kenneth Hughes , George Lahm , Thomas Selby , Thomas Stevenson
IPC分类号： C07D403/02 , A01N43/40
CPC分类号： A01N43/56 , A01N43/16 , A01N43/24 , A01N43/54 , A01N43/707 , A01N43/84 , A01N43/88 , A01N57/14 , A01N57/28 , A01N59/02 , A01N59/20 , A01N63/00 , A01N63/02 , C07D401/04 , Y02A50/322 , Y02A50/326 , Y02A50/352 , Y02A50/356 , Y02A50/371 , Y02A50/373 , Y02A50/375
摘要： This invention provides compounds of Formula (I), N-oxides and suitable salts thereof INSERT FORMULA I HERE wherein R1 is Me, Cl, Br or F; R2 is F, Cl, Br, C1-C4 haloalkyl or C1-C4 haloalkoxy; R3 is F, Cl or Br; R4 is H or C1-C4 alkyl, C3-C4 alkenyl, C3-C4 alkynyl, C3-C5 cycloalkyl, or C4-C6 cycloalkylalkyl, each optionally substituted with one substituent selected from the group consisting of halogen, CN, SMe S(O)Me, S(O)2Me and OMe; R5 is H or Me; R6 is H, F or Cl; and R7 is H, F or Cl. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula (I), an N-oxide thereof or a suitable salt of the compound (e.g., as a composition described herein). This invention also pertains to a composition for controlling an invertebrate pest comprising a biologically effective amount of a compound of Formula (I), an N-oxide thereof or a suitable salt of the compound and at least one additional component selected from the group consisting of a surfactant, a solid diluent and a liquid diluent.
摘要翻译：本发明提供了式（I）的化合物，N-氧化物及其合适的盐，其中R 1是Me，Cl，Br或F; R 2是F，Cl，Br，C 1 -C 4卤代烷基或C 1 -C 3 > 4卤代烷氧基; R 3是F，Cl或Br; R 4是H或C 1 -C 4烷基，C 3 -C 4烷基，C 3 -C 4烷基，C 3 -C 4烷基，亚烷基，C 3 -C 4炔基，C 3 -C 5环烷基或C

2. 发明申请

US20070264299A1 Cyano anthranilamide insecticides 有权
标题翻译：氰基邻氨基苯甲酰胺杀虫剂
公开(公告)号：US20070264299A1
公开(公告)日：2007-11-15
申请号：US11811105
申请日：2007-06-08
申请人： Kenneth Hughes , George Lahm , Thomas Selby , Thomas Stevenson
发明人： Kenneth Hughes , George Lahm , Thomas Selby , Thomas Stevenson
IPC分类号： A01N25/08 , A01M5/00 , A61K31/44 , C07D401/06
CPC分类号： A01N43/56 , A01N43/16 , A01N43/24 , A01N43/54 , A01N43/707 , A01N43/84 , A01N43/88 , A01N57/14 , A01N57/28 , A01N59/02 , A01N59/20 , A01N63/00 , A01N63/02 , C07D401/04 , Y02A50/322 , Y02A50/326 , Y02A50/352 , Y02A50/356 , Y02A50/371 , Y02A50/373 , Y02A50/375
摘要： This invention provides compounds of Formula 1, N-oxides and suitable salts thereof wherein R1 is Me, Cl, Br or F; R2 is F, Cl, Br, C1-C4 haloalkyl or C1-C4 haloalkoxy; R3 is F, Cl or Br; R4 is H; C1-C4 alkyl, C3-C4 alkenyl, C3-C4 alkynyl, C3-C5 cycloalkyl, or C4-C6 cycloalkylalkyl, each optionally substituted with one substituent selected from the group consisting of halogen, CN, SMe, S(O)Me, S(O)2Me, and OMe; R5 is H or Me; R6is H, F or Cl; and R7is H, F or Cl. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula 1, an N-oxide thereof or a suitable salt of the compound (e.g., as a composition described herein). This invention also pertains to a composition for controlling an invertebrate pest comprising a biologically effective amount of a compound of Formula 1, an N-oxide thereof or a suitable salt of the compound and at least one additional component selected from the group consisting of a surfactant, a solid diluent and a liquid diluent.
摘要翻译：本发明提供了其中R 1为Me，Cl，Br或F的式1化合物，N-氧化物及其合适的盐; R 2是F，Cl，Br，C 1 -C 4卤代烷基或C 1 -C 3 > 4卤代烷氧基; R 3是F，Cl或Br; R 4是H; C 1 -C 4烷基，C 3〜C 4链烯基，C 3

3. 发明申请

US20060014808A1 Novel anthranilamide insecticides 失效
标题翻译：新型邻氨基苯甲酰胺杀虫剂
公开(公告)号：US20060014808A1
公开(公告)日：2006-01-19
申请号：US10529612
申请日：2003-11-12
申请人： Kenneth Hughes , Thomas Selby , George Lahm
发明人： Kenneth Hughes , Thomas Selby , George Lahm
IPC分类号： A01N43/40 , A01N43/64 , A01N25/08
CPC分类号： C07D401/04 , A01N43/56 , C07D231/14 , C07D401/14
摘要： This invention provides compounds of Formula I, N-oxides and suitable salts thereof (INSERT FORMULA I HERE) wherein Y and V are each independently N or CR4a; W is N, CH or CR6; and R1 through R6, and n are as defined in the disclosure. This invention also pertains to a composition for controlling an invertebrate pest comprising a biologically effective amount of a compound of Formula I, an N-oxide thereof or an agronomic or nonagronomic suitable salt of the compound and at least one additional component selected from the group consisting of a surfactant, a solid diluent and a liquid diluent, and optionally further comprising an effective amount of at least one additional biologically active compound or agent. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula I, an N-oxide thereof or an agronomic or nonagronomic suitable salt of the compound or with the composition described herein.
摘要翻译：本发明提供式I化合物，N-氧化物及其合适的盐（其中Y和V各自独立地为N或CR 4a）; W是N，CH或CR 6; 和R 1至R 6，并且n如本公开所定义。本发明还涉及用于控制无脊椎害虫的组合物，其包含生物学有效量的式I化合物，其N-氧化物或化合物的农艺或非农学上合适的盐和至少一种选自以下的另外的组分：表面活性剂，固体稀释剂和液体稀释剂，并且任选地还包含有效量的至少一种另外的生物活性化合物或试剂。还公开了用于控制无脊椎害虫的方法，包括使无脊椎害虫或其环境与生物有效量的式I化合物，其N-氧化物或化合物的农艺或非农业合适的盐或与本文所述的组合物接触。

4. 发明申请

US20060289349A1 Composite materials for fluid treatment 审中-公开
标题翻译：用于流体处理的复合材料
公开(公告)号：US20060289349A1
公开(公告)日：2006-12-28
申请号：US11175986
申请日：2005-07-06
申请人： Kenneth Hughes
发明人： Kenneth Hughes
IPC分类号： B01D24/00
CPC分类号： B01J20/261 , A23L2/39 , A23L27/74 , A61L2/0082 , A61L2/16 , A61L12/08 , B01D35/02 , B01D53/02 , B01D53/1493 , B01D53/84 , B01D53/86 , B01D53/94 , B01D61/145 , B01D61/147 , B01D61/16 , B01D69/02 , B01D69/141 , B01D2311/04 , B01J20/02 , B01J20/0211 , B01J20/0218 , B01J20/0222 , B01J20/0229 , B01J20/0233 , B01J20/0237 , B01J20/0244 , B01J20/0248 , B01J20/0277 , B01J20/0281 , B01J20/0292 , B01J20/043 , B01J20/045 , B01J20/048 , B01J20/06 , B01J20/103 , B01J20/12 , B01J20/16 , B01J20/18 , B01J20/20 , B01J20/24 , B01J20/262 , B01J20/28042 , B01J2220/44 , B01J2220/46 , C02F1/003 , C02F1/28 , C02F1/288 , C02F1/50 , C02F1/52 , C02F1/66 , C02F1/70 , C02F1/72 , C02F1/76 , C02F1/766 , C02F1/78 , C02F2303/02 , C02F2305/04 , C02F2305/14 , Y02A50/2358 , B01D2311/12 , B01D2311/2688
摘要： This invention relates generally to composite materials and to devices which may alter fluid parameters. Devices incorporating the composite materials of the invention are used to deliver, remove, and generate, fluid treatment agents, and combinations thereof. These materials and devices are applicable to many different fluid processing situations including drinking water treatment, wastewater treatment, emission treatment, pollution cleanup, and sensing fluid composition. In its more particular aspects, the invention relates to the field of composites that may be widely tailored for many different treatment applications.
摘要翻译：本发明一般涉及复合材料和可改变流体参数的装置。结合本发明的复合材料的装置用于输送，除去和产生流体处理剂及其组合。这些材料和装置适用于许多不同的流体处理情况，包括饮用水处理，废水处理，排放处理，污染清理和传感液组成。在其更具体的方面，本发明涉及可以广泛地针对许多不同处理应用定制的复合材料领域。

5. 发明授权

US10350223B2 Compositions and methods for treating ocular diseases 有权
公开(公告)号：US10350223B2
公开(公告)日：2019-07-16
申请号：US15555527
申请日：2016-03-03
申请人： Richard W. Yee , Kenneth Hughes
发明人： Richard W. Yee , Kenneth Hughes
IPC分类号： A61K9/00 , A61K45/06 , A61K47/10 , A61K47/38 , A61K31/136 , A61K31/145 , A61K31/585
摘要： The compositions and methods disclosed herein provide for treatments of ocular disorders of the eye, such as ocular surface diseases as well as those associated with inflammation of internal cells and cell layers of the eye. The methods disclosed herein describe methods for treating ocular disorders, particularly dry eye disorders, comprising topically administering to an ocular region of a subject a composition comprising a pharmaceutically effective amount of at least one aldosterone antagonist or salt thereof and a pharmaceutically acceptable carrier. Included is a method for treating dry eye comprising topically administering to an ocular region of a subject a composition comprising spironolactone and hydroxypropyl methylcellulose; and reducing or preventing one or more symptoms or causes of dry eye.

6. 发明授权

US07270990B2 Virus production 有权
标题翻译：病毒生产
公开(公告)号：US07270990B2
公开(公告)日：2007-09-18
申请号：US10871768
申请日：2004-06-18
申请人： Gregory V. Williams , Kenneth Hughes
发明人： Gregory V. Williams , Kenneth Hughes
IPC分类号： C12P21/04 , C12P19/34 , C12N7/02 , C12N5/06 , C12N5/00
CPC分类号： C12N7/00 , A61K39/12 , A61K39/145 , C12N2760/16034 , C12N2760/16051
摘要： An improved process for recovery of virus from allantoic fluid of virus-infected chick embryos. Virus associated with granular and fibrous debris in the allantoic fluid can be disassociated from the debris and recovered, thereby increasing viral yield. Dissociation can be achieved by subjecting the virus-debris complex to conditions of increased salt concentrations, e.g., 0.5 M or greater.
摘要翻译：一种用于从病毒感染的鸡胚胎的尿囊液中回收病毒的改进方法。与尿囊液中的颗粒状和纤维碎片相关的病毒可与碎片分离并回收，从而增加病毒产量。可以通过使病毒碎片复合物进入增加的盐浓度，例如0.5M或更大的条件来实现解离。

7. 发明申请

US20060168356A1 Method and system for transmitting data for a shared application 有权
公开(公告)号：US20060168356A1
公开(公告)日：2006-07-27
申请号：US10859640
申请日：2004-06-03
申请人： Christopher Mairs , Anthony Downes , Roderick MacFarquhar , Kenneth Hughes , Alex Pollitt , John Batty , Mark Berry
发明人： Christopher Mairs , Anthony Downes , Roderick MacFarquhar , Kenneth Hughes , Alex Pollitt , John Batty , Mark Berry
IPC分类号： G06F3/00
CPC分类号： G06F3/1462 , G06T9/005
摘要： A method and system for compressing bitmap data in a system for sharing an application running on a host computer with a remote computer, wherein the shared application's screen output is simultaneously displayed on both computers. Simultaneous display of screen output is achieved by efficiently transmitting display data between the host computer and the remote computer. When a font used by the host computer for displaying text is not available on the remote computer, the host computer sends a bitmap representation of the text for display, rather than the text itself. Bitmap representations are cached by the remote computer, so that the same bitmap representation need not be repeatedly transmitted from the host computer to the remote computer. Bitmap representations are compressed by the host computer prior to transmission, transmitted, then decompressed by the computer.

8. 发明申请

US20050186223A1 Virus production 有权
标题翻译：病毒生产
公开(公告)号：US20050186223A1
公开(公告)日：2005-08-25
申请号：US10871768
申请日：2004-06-18
申请人： Gregory Williams , Kenneth Hughes
发明人： Gregory Williams , Kenneth Hughes
IPC分类号： A61K39/145 , A61K39/155 , C12N7/02
CPC分类号： C12N7/00 , A61K39/12 , A61K39/145 , C12N2760/16034 , C12N2760/16051
摘要： An improved process for recovery of virus from allantoic fluid of virus-infected chick embryos. Virus associated with granular and fibrous debris in the allantoic fluid can be disassociated from the debris and recovered, thereby increasing viral yield. Dissociation can be achieved by subjecting the virus-debris complex to conditions of increased salt concentrations, e.g., 0.5 M or greater.
摘要翻译：一种用于从病毒感染的鸡胚胎的尿囊液中回收病毒的改进方法。与尿囊液中的颗粒状和纤维碎片相关的病毒可与碎片分离并回收，从而增加病毒产量。可以通过使病毒碎片复合物进入增加的盐浓度，例如0.5M或更大的条件来实现解离。

9. 发明申请

US20050024389A1 Method and system for transmitting data for a shared application 审中-公开
标题翻译：用于共享应用程序传输数据的方法和系统
公开(公告)号：US20050024389A1
公开(公告)日：2005-02-03
申请号：US10859634
申请日：2004-06-03
申请人： Christopher Mairs , Anthony Downes , Roderick MacFarquhar , Kenneth Hughes , Alex Pollitt , John Batty , Mark Berry
发明人： Christopher Mairs , Anthony Downes , Roderick MacFarquhar , Kenneth Hughes , Alex Pollitt , John Batty , Mark Berry
IPC分类号： G06F3/14 , G06T9/00 , G06F3/00
CPC分类号： G06F3/1462 , G06T9/005
摘要： A method and system for compressing bitmap data in a system for sharing an application running on a host computer with a remote computer, wherein the shared application's screen output is simultaneously displayed on both computers. Simultaneous display of screen output is achieved by efficiently transmitting display data between the host computer and the remote computer. When a font used by the host computer for displaying text is not available on the remote computer, the host computer sends a bitmap representation of the text for display, rather than the text itself. Bitmap representations are cached by the remote computer, so that the same bitmap representation need not be repeatedly transmitted from the host computer to the remote computer. Bitmap representations are compressed by the host computer prior to transmission, transmitted, then decompressed by the computer.
摘要翻译：一种在系统中压缩位图数据的方法和系统，用于与远程计算机共享在主机上运行的应用，其中共享应用的屏幕输出同时显示在两台计算机上。通过在主机和远程计算机之间高效地传输显示数据，实现屏幕输出的同时显示。当主机用于显示文本的字体在远程计算机上不可用时，主机计算机发送用于显示的文本的位图表示，而不是文本本身。位图表示由远程计算机缓存，使得相同的位图表示不需要从主机重复地发送到远程计算机。位图表示在传输之前由主机压缩，发送，然后由计算机解压缩。

10. 发明申请

US20180050049A1 COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES 审中-公开
公开(公告)号：US20180050049A1
公开(公告)日：2018-02-22
申请号：US15555527
申请日：2016-03-03
申请人： Richard W. Yee , Kenneth Hughes
发明人： Richard W. Yee , Kenneth Hughes
IPC分类号： A61K31/585 , A61K9/00 , A61K47/10 , A61K45/06 , A61K31/145 , A61K47/38
CPC分类号： A61K31/585 , A61K9/0048 , A61K31/136 , A61K31/145 , A61K45/06 , A61K47/10 , A61K47/38 , A61K2300/00
摘要： The compositions and methods disclosed herein provide for treatments of ocular disorders of the eye, such as ocular surface diseases as well as those associated with inflammation of internal cells and cell layers of the eye. The methods disclosed herein describe methods for treating ocular disorders, particularly dry eye disorders, comprising topically administering to an ocular region of a subject a composition comprising a pharmaceutically effective amount of at least one aldosterone antagonist or salt thereof and a pharmaceutically acceptable carrier. Included is a method for treating dry eye comprising topically administering to an ocular region of a subject a composition comprising spironolactone and hydroxypropyl methylcellulose; and reducing or preventing one or more symptoms or causes of dry eye.

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