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1. 发明授权

US4228383A Speed control circuit arrangement for an AC commutator motor 失效
标题翻译：用于交流换向器电机的速度控制电路装置
公开(公告)号：US4228383A
公开(公告)日：1980-10-14
申请号：US974116
申请日：1978-12-28
申请人： Katsuji Soeda , Mitsuhiro Oyama , Fumio Sakuma , Tadashi Nakajima
发明人： Katsuji Soeda , Mitsuhiro Oyama , Fumio Sakuma , Tadashi Nakajima
IPC分类号： H02P25/04 , H02P25/14 , H02P27/02 , H02P5/40 , H02P7/28
CPC分类号： H02P25/14
摘要： A speed control circuit arrangement for controlling a rotational speed of an AC commutator motor by an AC controlled rectifier element. The speed control circuit arrangement comprises a pulse transformer which is connected at the secondary winding to the control electrode of the AC controlled rectifier element and one of two main electrodes of the controlled rectifier element and supplies a trigger pulse to the control electrode, a variable resistor for adjusting the rotational speed of the motor, a first capacitor connected at one end through the variable resistor to the other main electrode and at the other end to one end of an AC power source, a pulse generating element connected across said first capacitor with the primary winding of the pulse transformer intervening therebetween, and a first resistor connected at one end to the one main electrode and at the other end to the other end of the AC power source through the first capacitor. With such a construction, an inductive voltage regenerated in the armature of the motor (hereinafter referred to as a flash voltage) is effectively used to perform a stable operation of the AC commutator motor at a low speed.
摘要翻译：一种速度控制电路装置，用于通过交流控制整流元件控制交流换向马达的转速。速度控制电路装置包括脉冲变压器，该脉冲变压器在次级绕组处连接到可控整流元件的控制电极和可控整流元件的两个主电极中的一个，并向控制电极提供触发脉冲，可变电阻器用于调节电动机的转速;第一电容器，其一端通过可变电阻器连接到另一主电极，另一端连接到交流电源的一端;脉冲发生元件，连接在所述第一电容器与介于其间的脉冲变压器的初级绕组，以及第一电阻器，其一端通过第一电容器连接到一个主电极，另一端连接到交流电源的另一端。通过这样的结构，在电动机的电枢中再生的感应电压（以下称为闪光电压）被有效地用于以低速执行AC换向器电动机的稳定运行。

2. 发明申请

US20110039891A1 Methods for treating a disease in which Rho kinase is involved 有权
标题翻译：治疗涉及Rho激酶的疾病的方法
公开(公告)号：US20110039891A1
公开(公告)日：2011-02-17
申请号：US12925367
申请日：2010-10-20
申请人： Masahiko Hagihara , Ken-ichi Komori , Hidetoshi Sunamoto , Hiroshi Nishida , Takeshi Matsugi , Tadashi Nakajima , Masakazu Hatano , Kazutaka Kido , Hideaki Hara
发明人： Masahiko Hagihara , Ken-ichi Komori , Hidetoshi Sunamoto , Hiroshi Nishida , Takeshi Matsugi , Tadashi Nakajima , Masakazu Hatano , Kazutaka Kido , Hideaki Hara
IPC分类号： A61K31/454 , A61K31/415 , A61K31/4439 , A61K31/422 , A61K31/42 , A61P27/02 , A61P27/06
CPC分类号： C07D231/56 , C07D401/04 , C07D403/04 , C07D413/04
摘要： A method for treating a disease in which Rho kinase is involved. The method is carried out by administering to a patient in need thereof a pharmaceutically effective amount of a compound of the following formula or a pharmaceutically acceptable salt thereof: wherein the ring X is a benzene ring or a pyridine ring; R1 and R2 are hydrogen or alkyl or together form a cycloalkene ring; R3 is hydrogen, substituted alkyl, unsubstituted alkenyl, carboxyl or an ester or an amide thereof, amino or a cyano; R4 is hydrogen, hydroxyl, substituted or unsubstituted alkoxy, unsubstituted alkenyloxy, unsubstituted cycloalkyloxy substituted or unsubstituted alkyl, unsubstituted alkenyl, unsubstituted cycloalkyl, amino, substituted or unsubstituted alkylamino, nitro, cyano or a monocyclic heterocycle; and R5 is a halogen atom or a hydrogen atom.
摘要翻译：一种治疗涉及Rho激酶的疾病的方法。该方法通过向有需要的患者施用药学有效量的下式化合物或其药学上可接受的盐进行：其中环X是苯环或吡啶环; R1和R2是氢或烷基或一起形成环烯烃环; R 3是氢，取代的烷基，未取代的烯基，羧基或其酯或酰胺，氨基或氰基; R4是氢，羟基，取代或未取代的烷氧基，未取代的烯氧基，未取代的环烷基氧基取代或未取代的烷基，未取代的烯基，未取代的环烷基，氨基，取代或未取代的烷基氨基，硝基，氰基或单环杂环; R5为卤素原子或氢原子。

3. 发明授权

US07855222B2 Methods for treating a disease in which Rho kinase is involved 有权
标题翻译：治疗涉及Rho激酶的疾病的方法
公开(公告)号：US07855222B2
公开(公告)日：2010-12-21
申请号：US12456652
申请日：2009-06-19
申请人： Masahiko Hagihara , Ken-ichi Komori , Hidetoshi Sunamoto , Hiroshi Nishida , Takeshi Matsugi , Tadashi Nakajima , Masakazu Hatano , Kazutaka Kido , Hideaki Hara
发明人： Masahiko Hagihara , Ken-ichi Komori , Hidetoshi Sunamoto , Hiroshi Nishida , Takeshi Matsugi , Tadashi Nakajima , Masakazu Hatano , Kazutaka Kido , Hideaki Hara
IPC分类号： A01N43/56 , A61K31/40 , C07D231/00 , C07D233/56
CPC分类号： C07D231/56 , C07D401/04 , C07D403/04 , C07D413/04
摘要： A method for treating a disease in which Rho kinase is involved. The method is carried out by administering to a patient in need thereof a pharmaceutically effective amount of a compound of the following formula or a pharmaceutically acceptable salt thereof: wherein the ring X is a benzene ring or a pyridine ring; R1 and R2 are hydrogen or alkyl or together form a cycloalkene ring; R3 is hydrogen, substituted alkyl, unsubstituted alkenyl, carboxyl or an ester or an amide thereof, amino or a cyano; R4 is hydrogen, hydroxyl, substituted or unsubstituted alkoxy, unsubstituted alkenyloxy, unsubstituted cycloalkyloxy, substituted or unsubstituted alkyl, unsubstituted alkenyl, unsubstituted cycloalkyl, amino, substituted or unsubstituted alkylamino, nitro, cyano or a monocyclic heterocycle; and R5 is a halogen atom or a hydrogen atom.
摘要翻译：一种治疗涉及Rho激酶的疾病的方法。该方法通过向有需要的患者施用药学有效量的下式化合物或其药学上可接受的盐进行：其中环X是苯环或吡啶环; R1和R2是氢或烷基或一起形成环烯烃环; R 3是氢，取代的烷基，未取代的烯基，羧基或其酯或酰胺，氨基或氰基; R4是氢，羟基，取代或未取代的烷氧基，未取代的烯氧基，未取代的环烷基氧基，取代或未取代的烷基，未取代的烯基，未被取代的环烷基，氨基，取代或未取代的烷基氨基，硝基，氰基或单环杂环; R5为卤素原子或氢原子。

4. 发明申请

US20090264468A1 Methods for treating a disease in which Rho kinase is involved 有权
标题翻译：治疗涉及Rho激酶的疾病的方法
公开(公告)号：US20090264468A1
公开(公告)日：2009-10-22
申请号：US12456652
申请日：2009-06-19
申请人： Masahiko Hagihara , Ken-ichi Komori , Hidetoshi Sunamoto , Hiroshi Nishida , Takeshi Matsugi , Tadashi Nakajima , Masakazu Hatano , Kazutaka Kido , Hideaki Hara
发明人： Masahiko Hagihara , Ken-ichi Komori , Hidetoshi Sunamoto , Hiroshi Nishida , Takeshi Matsugi , Tadashi Nakajima , Masakazu Hatano , Kazutaka Kido , Hideaki Hara
IPC分类号： A61K31/454 , A61K31/416 , A61K31/4439 , A61K31/421 , A61K31/42 , A61P9/00 , A61P11/00 , A61P35/00 , A61P29/00 , A61P15/00
CPC分类号： C07D231/56 , C07D401/04 , C07D403/04 , C07D413/04
摘要： A method for treating a disease in which Rho kinase is involved. The method is carried out by administering to a patient in need thereof a pharmaceutically effective amount of a compound of the following formula or a pharmaceutically acceptable salt thereof: , wherein the ring X is a benzene ring or a pyridine ring; R1 and R2 are hydrogen or alkyl or together form a cycloalkene ring; R3 is hydrogen, substituted alkyl, unsubstituted alkenyl, carboxyl or an ester or an amide thereof, amino or a cyano; R4 is hydrogen, hydroxyl, substituted or unsubstituted alkoxy, unsubstituted alkenyloxy, unsubstituted cycloalkyloxy, substituted or unsubstituted alkyl, unsubstituted alkenyl, unsubstituted cycloalkyl, amino, substituted or unsubstituted alkylamino, nitro, cyano or a monocyclic heterocycle; and R5 is a halogen atom or a hydrogen atom.
摘要翻译：一种治疗涉及Rho激酶的疾病的方法。该方法通过向有需要的患者施用药学有效量的下式化合物或其药学上可接受的盐进行：其中环X是苯环或吡啶环; R1和R2是氢或烷基或一起形成环烯烃环; R 3是氢，取代的烷基，未取代的烯基，羧基或其酯或酰胺，氨基或氰基; R4是氢，羟基，取代或未取代的烷氧基，未取代的烯氧基，未取代的环烷基氧基，取代或未取代的烷基，未取代的烯基，未被取代的环烷基，氨基，取代或未取代的烷基氨基，硝基，氰基或单环杂环; R5为卤素原子或氢原子。

5. 发明授权

US07563906B2 Indazole derivatives 失效
标题翻译：吲唑衍生物
公开(公告)号：US07563906B2
公开(公告)日：2009-07-21
申请号：US10575645
申请日：2004-10-15
申请人： Masahiko Hagihara , Ken-ichi Komori , Hidetoshi Sunamoto , Hiroshi Nishida , Takeshi Matsugi , Tadashi Nakajima , Masakazu Hatano , Kazutaka Kido , Hideaki Hara
发明人： Masahiko Hagihara , Ken-ichi Komori , Hidetoshi Sunamoto , Hiroshi Nishida , Takeshi Matsugi , Tadashi Nakajima , Masakazu Hatano , Kazutaka Kido , Hideaki Hara
IPC分类号： C07D233/00
CPC分类号： C07D231/56 , C07D401/04 , C07D403/04 , C07D413/04
摘要： An object of the present invention is to create a novel indazole derivative useful as a drug and to find a novel pharmacological action of the derivative. The compound of the present invention is represented by the formula [I] and has an excellent Rho kinase inhibiting action. In the formula, a ring X is a benzene ring or a pyridine ring; R1 and R2 are H or alkyl; R3 and R4 are halogen, H, OH, alkoxy, alkenyloxy, alkynyloxy, cycloalkyloxy, cycloalkenyloxy, aryloxy, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl, carboxy, hydrocarbonyl, alkylcarbonyl, etc.; and R5 is halogen atom, H, OH, alkoxy, aryloxy, alkyl or aryl. Each group can be substituted.
摘要翻译：本发明的目的是产生一种可用作药物的新型吲唑衍生物，并找到该衍生物的新药理作用。本发明的化合物由式[I]表示，具有优异的Rho激酶抑制作用。在该式中，环X为苯环或吡啶环; R1和R2是H或烷基; R 3和R 4是卤素，H，OH，烷氧基，烯氧基，炔氧基，环烷氧基，环烯氧基，芳氧基，烷基，烯基，炔基，环烷基，环烯基，芳基，羧基，烃基，烷基羰基等。和R 5是卤素原子，H，OH，烷氧基，芳氧基，烷基或芳基。每组可以替代。

6. 发明授权

US4904842A Blowhole.multidot.pit preventing agent and arc-welding method using the same 失效
标题翻译：防泡剂和使用其的电弧焊接方法
公开(公告)号：US4904842A
公开(公告)日：1990-02-27
申请号：US111870
申请日：1987-10-21
申请人： Koichi Yasuda , Shosaburo Nakano , Noboru Nishiyama , Takaro Matsumoto , Katsuaki Nakatsuji , Tadao Komatsu , Tadashi Nakajima
发明人： Koichi Yasuda , Shosaburo Nakano , Noboru Nishiyama , Takaro Matsumoto , Katsuaki Nakatsuji , Tadao Komatsu , Tadashi Nakajima
IPC分类号： B23K9/235 , B23K35/22
CPC分类号： B23K9/235 , B23K35/226
摘要： In lap joint welding of galvanized sheets, the occurence of blowhole and pit is prevented by applying a blowhole.multidot.pit preventing agent comprising a phosphorus compound as an effective ingredient prior to the arc-welding.

7. 发明授权

US09096782B2 Polyesters, polyester compositions, pressure-sensitive adhesive compositions, pressure-sensitive adhesive layers and pressure-sensitive adhesive sheets 有权
标题翻译：聚酯，聚酯组合物，压敏粘合剂组合物，压敏粘合剂层和压敏粘合片
公开(公告)号：US09096782B2
公开(公告)日：2015-08-04
申请号：US13057689
申请日：2009-08-05
申请人： Hitoshi Takahira , Satomi Yoshie , Tadashi Nakajima , Daiki Funaoka , Katsuya Shimeno
发明人： Hitoshi Takahira , Satomi Yoshie , Tadashi Nakajima , Daiki Funaoka , Katsuya Shimeno
IPC分类号： C08G63/08 , C08G63/16 , C09J167/04 , C09J175/06 , C08G18/42 , C08G18/79 , C08G63/60 , C09J167/00 , C09J175/04 , C09J7/02
CPC分类号： C09J175/06 , C08G18/4202 , C08G18/4233 , C08G18/428 , C08G18/792 , C08G63/60 , C08G2170/40 , C09J7/38 , C09J167/00 , C09J175/04 , C09J2467/00 , Y10T428/2852
摘要： The present invention provides a polyester, a polyester composition and a pressure-sensitive adhesive composition capable of obtaining a pressure-sensitive adhesive which is global-environmentally friendly and is excellent in pressure-sensitive adhesion properties, using a plant-derived raw material; and a pressure-sensitive adhesive layer and a pressure-sensitive adhesive sheet which can be obtained by using the same. A polyester of the present invention is a polyester comprising at least a lactic acid unit, a dibasic acid unit and a glycol unit, wherein the dibasic acid unit contains dimer acid, and the polyester has a glass transition temperature as measured at a temperature rising rate of 20° C./minute using a differential scanning calorimeter, of −70 to −20° C., a weight average molecular weight of 20,000 to 300,000 and a hydroxyl value of 1 to 100 mgKOH/g.
摘要翻译：本发明提供一种能够使用植物来源的原料获得全球环保且压敏粘合性优异的压敏粘合剂的聚酯，聚酯组合物和压敏粘合剂组合物; 以及可以通过使用它们获得的压敏粘合剂层和压敏粘合片。本发明的聚酯是至少包含乳酸单元，二元酸单元和二醇单元的聚酯，其中二元酸单元含有二聚酸，聚酯具有以升温速度测定的玻璃化转变温度使用差示扫描量热计为20℃/分钟，为-70〜-20℃，重均分子量为20,000〜300,000，羟基值为1〜100mgKOH / g。

8. 发明授权

US08232308B2 Methods for treating a disease in which Rho kinase is involved 有权
标题翻译：治疗涉及Rho激酶的疾病的方法
公开(公告)号：US08232308B2
公开(公告)日：2012-07-31
申请号：US12925367
申请日：2010-10-20
申请人： Masahiko Hagihara , Ken-ichi Komori , Hidetoshi Sunamoto , Hiroshi Nishida , Takeshi Matsugi , Tadashi Nakajima , Masakazu Hatano , Kazutaka Kido , Hideaki Hara
发明人： Masahiko Hagihara , Ken-ichi Komori , Hidetoshi Sunamoto , Hiroshi Nishida , Takeshi Matsugi , Tadashi Nakajima , Masakazu Hatano , Kazutaka Kido , Hideaki Hara
IPC分类号： A01N43/56 , A61K31/40 , C07D231/00 , C07D233/56
CPC分类号： C07D231/56 , C07D401/04 , C07D403/04 , C07D413/04
摘要： A method for treating a disease in which Rho kinase is involved. The method is carried out by administering to a patient in need thereof a pharmaceutically effective amount of a compound of the following formula or a pharmaceutically acceptable salt thereof: wherein the ring X is a benzene ring or a pyridine ring; R1 and R2 are hydrogen or alkyl or together form a cycloalkene ring; R3 is hydrogen, substituted alkyl, unsubstituted alkenyl, carboxyl or an ester or an amide thereof, amino or a cyano; R4 is hydrogen, hydroxyl, substituted or unsubstituted alkoxy, unsubstituted alkenyloxy, unsubstituted cycloalkyloxy substituted or unsubstituted alkyl, unsubstituted alkenyl, unsubstituted cycloalkyl, amino, substituted or unsubstituted alkylamino, nitro, cyano or a monocyclic heterocycle; and R5 is a halogen atom or a hydrogen atom.
摘要翻译：一种治疗涉及Rho激酶的疾病的方法。该方法通过向有需要的患者施用药学有效量的下式化合物或其药学上可接受的盐进行：其中环X是苯环或吡啶环; R1和R2是氢或烷基或一起形成环烯烃环; R 3是氢，取代的烷基，未取代的烯基，羧基或其酯或酰胺，氨基或氰基; R4是氢，羟基，取代或未取代的烷氧基，未取代的烯氧基，未取代的环烷基氧基取代或未取代的烷基，未取代的烯基，未取代的环烷基，氨基，取代或未取代的烷基氨基，硝基，氰基或单环杂环; R5为卤素原子或氢原子。

9. 发明申请

US20100041671A1 Methods for treating glaucoma 审中-公开
标题翻译：治疗青光眼的方法
公开(公告)号：US20100041671A1
公开(公告)日：2010-02-18
申请号：US12589073
申请日：2009-10-16
申请人： Tadashi Nakajima , Takeshi Matsugi , Hideaki Hara
发明人： Tadashi Nakajima , Takeshi Matsugi , Hideaki Hara
IPC分类号： A61K31/437 , A61K31/496 , A61P27/06
CPC分类号： A61K45/06 , A61K9/0048 , A61K31/437 , A61K31/4409 , A61K31/4725 , A61K31/5377 , A61K31/553 , A61K31/5575 , A61K2300/00
摘要： A method for treating glaucoma comprising administering to a patient pharmaceutically effective amounts of a Rho kinase inhibitor and a prostaglandin.
摘要翻译：一种治疗青光眼的方法，包括向患者施用药物有效量的Rho激酶抑制剂和前列腺素。

10. 发明授权

US5985920A Difluoroprostaglandin derivatives and their use 有权
标题翻译：二氟前列腺素衍生物及其用途
公开(公告)号：US5985920A
公开(公告)日：1999-11-16
申请号：US127804
申请日：1998-08-03
申请人： Eiichi Shirasawa , Masaaki Kageyama , Tadashi Nakajima , Takashi Nakano , Nobuaki Mori , Hideshi Sasakura , Yasushi Matsumura , Yoshitomi Morizawa
发明人： Eiichi Shirasawa , Masaaki Kageyama , Tadashi Nakajima , Takashi Nakano , Nobuaki Mori , Hideshi Sasakura , Yasushi Matsumura , Yoshitomi Morizawa
IPC分类号： A61K31/5575 , A61K31/557 , A61P27/02 , A61P27/06 , C07C405/00
CPC分类号： C07C405/00 , C07C405/0016 , C07C405/0033
摘要： A fluorine-containing prostaglandin derivative of the formula (1) (or a salt thereof) and a medicine containing it, particularly, a preventive or therapeutic medicine for an eye disease: ##STR1## wherein A is a vinylene group or the like, R.sup.1 is an aryloxyalkyl group or the like, R.sup.2 and R.sup.3 are hydrogen atoms or the like, and Z is OR.sup.4 (wherein OR.sup.4 is a hydrogen atom or an alkyl group) or the like.
摘要翻译：式（1）的含氟前列腺素衍生物（或其盐）和含有其的药物，特别是眼部疾病的预防或治疗药物：其中A为亚乙烯基等，R 1为芳氧基烷基基团等，R2和R3是氢原子等，Z是OR4（其中OR4是氢原子或烷基）等。

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