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1. 发明授权

US07682009B1 Cooling, condensation and freezing of atmospheric water or of a microfluidic working-material in or on microfluidic devices 失效
标题翻译：微流体装置中或微流体装置上的大气水或微流体工作材料的冷却，冷凝和冷冻
公开(公告)号：US07682009B1
公开(公告)日：2010-03-23
申请号：US11141350
申请日：2005-05-31
申请人： John W. Sliwa, Jr. , Carol A. Tosaya
发明人： John W. Sliwa, Jr. , Carol A. Tosaya
IPC分类号： B41J2/17
CPC分类号： B41J29/377
摘要： Condensation of water from a gas, such as from atmospheric air or other nearby ambient gas, is provided for use in a variety of jetting devices, such as inkjet and lab-on-a-chip applications. Further embodiments involve the use of frozen liquids, not limited to frozen condensed water, and microcooling of fluidic components or working materials for improved process control and reliability.
摘要翻译：提供来自气体（例如来自大气或其他附近环境气体）的水的冷凝用于各种喷射装置，例如喷墨和实验室在芯片上的应用。进一步的实施方案涉及使用冷冻液体，不限于冷冻冷凝水，以及使用流体组分或工作材料的显微冷却，以改善工艺控制和可靠性。

2. 发明授权

US07082395B2 Signal injection coupling into the human vocal tract for robust audible and inaudible voice recognition 有权
公开(公告)号：US07082395B2
公开(公告)日：2006-07-25
申请号：US10265468
申请日：2002-10-03
申请人： Carol A. Tosaya , John W. Sliwa, Jr.
发明人： Carol A. Tosaya , John W. Sliwa, Jr.
IPC分类号： G10L15/00
CPC分类号： G10L15/20 , G10L19/08
摘要： A means and method are provided for enhancing or replacing the natural excitation of the human vocal tract by artificial excitation means, wherein the artificially created acoustics present additional spectral, temporal, or phase data useful for (1) enhancing the machine recognition robustness of audible speech or (2) enabling more robust machine-recognition of relatively inaudible mouthed or whispered speech. The artificial excitation (a) may be arranged to be audible or inaudible, (b) may be designed to be non-interfering with another user's similar means, (c) may be used in one or both of a vocal content-enhancement mode or a complimentary vocal tract-probing mode, and/or (d) may be used for the recognition of audible or inaudible continuous speech or isolated spoken commands.

3. 发明授权

US08083707B2 Non-contact damage-free ultrasonic cleaning of implanted or natural structures having moving parts and located in a living body 有权
标题翻译：具有运动部件并位于生物体内的植入式或天然结构的非接触式无损伤超声波清洗
公开(公告)号：US08083707B2
公开(公告)日：2011-12-27
申请号：US10826232
申请日：2004-04-16
申请人： Carol A. Tosaya , John W. Sliwa, Jr.
发明人： Carol A. Tosaya , John W. Sliwa, Jr.
IPC分类号： A61B17/20
CPC分类号： A61B17/22004 , A61B90/37 , A61B2017/00243 , A61B2017/22098
摘要： Ultrasonic, sonic or vibratory energy, delivered non-invasively, minimally invasively or invasively (e.g. surgically), is utilized to provide direct cleaning action at or to the location of the implanted device such as a prosthetic heart valve with undesirable deposits of at least some amount thereon or therein. Such ultra-sound energy may be aided by the use of a drug in association or cooperation with the acoustic irradiation. The “cleaning” acoustic energy may optionally be delivered under the guidance of an imaging modality and may be delivered in a timed or gated manner such that the valve occluders or leaflets are in a preferred position (assuming they are functioning) during exposures.
摘要翻译：超声波，声波或振动能量非侵入性地以最小的侵入性或侵入性（例如外科手术）被使用，以在植入装置的位置处或位置处提供直接清洁作用，例如假体心脏瓣膜，其具有至少一些不期望的沉积在其上或其中。这种超声能量可以通过使用与声辐射相关联或配合的药物来辅助。 “清洁”声能可以任选地在成像模态的指导下传送，并且可以以定时或门控的方式递送，使得在曝光期间，阀封闭器或传单处于优选位置（假设它们正在起作用）。

4. 发明授权

US07735945B1 Microbubble and microdroplet switching, manipulation and modulation of acoustic, electromagnetic and electrical waves, energies and potentials 有权
标题翻译：微泡和微滴切换，声学，电磁和电波，能量和电位的操纵和调制
公开(公告)号：US07735945B1
公开(公告)日：2010-06-15
申请号：US11035488
申请日：2005-01-13
申请人： John W. Sliwa, Jr. , Carol A. Tosaya
发明人： John W. Sliwa, Jr. , Carol A. Tosaya
IPC分类号： B41J29/38 , B41J2/015 , B41J2/04 , B41J2/045 , B41J2/02
CPC分类号： B41J2/04
摘要： The formation and manipulation of microbubbles, microdroplets and films of (preferably) flowable materials, such as liquids and gases, are used to beneficially control or modulate acoustic-energy propagation, electromagnetic-energy propagation or electrical potential and current application. A droplet, bubble or film causes at least one of reflection, refraction, diffraction, attenuation, sapping, scattering, dissipation, redirection, conversion or blocking of at least one component of the energy due to the droplet, bubble or film causing a propagation discontinuity, disruption or energy-barrier to the energy. The energy comprises at least one of acoustic, electrical, electromagnetic, magnetic, kinetic, mechanical, chemical, RF, thermal, pneumatic, hydraulic or non-visible optical energy.
摘要翻译：使用微泡，微滴和（优选）可流动材料（例如液体和气体）的形成和操作来有利地控制或调节声能传播，电磁能传播或电位和电流施加。液滴，气泡或膜会导致由于液滴，气泡或膜引起传播不连续性而导致的能量的至少一个分量的反射，折射，衍射，衰减，扫描，散射，耗散，重定向，转换或阻挡中的至少一种，能量的破坏或能量障碍。能量包括声学，电学，电磁，磁性，动力学，机械，化学，RF，热，气动，液压或不可见光能中的至少一种。

5. 发明授权

US06487531B1 Signal injection coupling into the human vocal tract for robust audible and inaudible voice recognition 有权
标题翻译：信号注入耦合到人类声道中，用于强大的可听和听不清的语音识别
公开(公告)号：US06487531B1
公开(公告)日：2002-11-26
申请号：US09348600
申请日：1999-07-06
申请人： Carol A. Tosaya , John W. Sliwa, Jr.
发明人： Carol A. Tosaya , John W. Sliwa, Jr.
IPC分类号： G10L1500
CPC分类号： G10L15/20 , G10L19/08
摘要： A means and method are provided for enhancing or replacing the natural excitation of the human vocal tract by artificial excitation means, wherein the artificially created acoustics present additional spectral, temporal, or phase data useful for (1) enhancing the machine recognition robustness of audible speech or (2) enabling more robust machine-recognition of relatively inaudible mouthed or whispered speech. The artificial excitation (a) may be arranged to be audible or inaudible, (b) may be designed to be non-interfering with another user's similar means, (c) may be used in one or both of a vocal content-enhancement mode or a complimentary vocal tract-probing mode, and/or (d) may be used for the recognition of audible or inaudible continuous speech or isolated spoken commands.
摘要翻译：提供了一种手段和方法，用于通过人造激励装置增强或替代人类声道的自然激发，其中人为产生的声学表现出对于（1）增强听觉语音的机器识别鲁棒性的附加频谱，时间或相位数据或者（2）能使机器更可靠地识别相对听不到的口音或低声说话。可以将人造激励（a）设置为可听或听不到，（b）可被设计成不干扰另一用户的类似装置，（c）可以用于声乐内容增强模式或一个免费的声道探测模式，和/或（d）可以用于识别可听或听不清的连续语音或孤立的语音命令。

6. 发明授权

US09089287B2 Image-guided ablation system and method for monitoring an ablation procedure 有权
标题翻译：图像引导消融系统和消融程序监测方法
公开(公告)号：US09089287B2
公开(公告)日：2015-07-28
申请号：US12346132
申请日：2008-12-30
申请人： John W. Sliwa, Jr. , Stephen A. Morse
发明人： John W. Sliwa, Jr. , Stephen A. Morse
IPC分类号： A61B8/00 , A61B18/14 , A61B8/12 , A61B8/08 , A61B18/02 , A61B18/18 , A61B18/20 , A61B19/00 , A61N7/02
CPC分类号： A61B8/12 , A61B8/00 , A61B8/0841 , A61B8/4245 , A61B8/445 , A61B8/463 , A61B18/02 , A61B18/14 , A61B18/18 , A61B18/20 , A61B2090/3782 , A61B2090/3784 , A61N7/02 , A61N7/022
摘要： An ablation system comprises a tool including an shaft having proximal and distal end portions, a handle at the proximal end portion, and a lumen extending between the proximal and distal end portions. The system further includes an ablation subsystem comprised of an ablation element at the distal end portion of the shaft, and an ablation source connected to the ablation element. The system further includes an imaging subsystem comprising an ultrasound imaging transducer disposed proximate the ablation element. The transducer is pivotally attached to the shaft or the ablation element to allow the transducer to articulate between stowed and deployed positions. The imaging subsystem further comprises a processor connected to the transducer configured to receive image data acquired by the transducer, and to generate an image corresponding thereto. The imaging subsystem still further includes a display connected to the processor configured to display the generated image.
摘要翻译：消融系统包括工具，其包括具有近端部分和远端部分的轴，在近端部分处的手柄以及在近端部分和远端部分之间延伸的内腔。该系统还包括消融子系统，其包括在轴的远端部分处的消融元件和连接到消融元件的消融源。该系统还包括成像子系统，其包括邻近消融元件设置的超声成像换能器。换能器枢转地附接到轴或消融元件，以允许换能器在收起位置和展开位置之间铰接。成像子系统还包括连接到换能器的处理器，其被配置为接收由换能器获取的图像数据，并且生成与其对应的图像。成像子系统还包括连接到处理器的显示器，其被配置为显示生成的图像。

7. 发明授权

US06359367B1 Micromachined ultrasonic spiral arrays for medical diagnostic imaging 失效
标题翻译：用于医疗诊断成像的微加工超声波螺旋阵列
公开(公告)号：US06359367B1
公开(公告)日：2002-03-19
申请号：US09455881
申请日：1999-12-06
申请人： Thilaka S. Sumanaweera , Sevig Ayter , John W. Sliwa, Jr.
发明人： Thilaka S. Sumanaweera , Sevig Ayter , John W. Sliwa, Jr.
IPC分类号： H02N100
CPC分类号： B06B1/0292
摘要： Spiral, sparse spiral, substantially spiral or substantially sparse spiral transducer arrays comprising capacitive micromachined ultrasonic transducer elements disposed on a silicon substrate, and ultrasound imaging systems employing same. The transducer elements are respectively coupled to a plurality of amplifiers. Imager electronics are coupled to each of the amplifiers and drives the transducer elements and/or generates an output of the spiral transducer array. The amplifiers may be located in the silicon substrate containing the transducer elements, or on a separate substrate that is interconnected to the substrate containing the transducer elements using bumps, for example. Electrical interconnection to the transducer elements may readily be achieved without interfering with the acoustic output of the transducer elements.
摘要翻译：包括设置在硅衬底上的电容微加工超声换能器元件的螺旋，稀疏螺旋，基本螺旋或基本上稀疏的螺旋形换能器阵列，以及采用其的超声成像系统。换能器元件分别耦合到多个放大器。成像仪电子器件耦合到每个放大器并驱动换能器元件和/或产生螺旋换能器阵列的输出。放大器可以位于包含换能器元件的硅衬底中，或者位于使用例如使用凸块互连到包含换能器元件的衬底的单独衬底上。可以容易地实现与换能器元件的电互连，而不会干扰换能器元件的声输出。

8. 发明授权

US06222948B1 Multiple ultrasound image registration system, method and transducer 有权
公开(公告)号：US06222948B1
公开(公告)日：2001-04-24
申请号：US09502607
申请日：2000-02-11
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： G06K900
CPC分类号： A61B8/145 , A61B8/483 , G01S7/52034 , G01S7/52065 , G01S7/52071 , G01S7/52085 , G01S15/66 , G01S15/87 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G06T7/246
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.

9. 发明授权

US06201900B1 Multiple ultrasound image registration system, method and transducer 有权
标题翻译：多重超声图像配准系统，方法和传感器
公开(公告)号：US06201900B1
公开(公告)日：2001-03-13
申请号：US09340542
申请日：1999-06-28
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： G06K900
CPC分类号： A61B8/145 , A61B8/483 , G01S7/52034 , G01S7/52065 , G01S7/52071 , G01S7/52085 , G01S15/66 , G01S15/87 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G06T7/246
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.
摘要翻译：超声波成像系统包括在图像数据阵列的每一端具有图像数据阵列和跟踪阵列的超声波换能器。跟踪阵列横向于图像数据阵列。来自图像数据阵列的图像用于重建目标的三维表示。基于来自跟踪阵列的数据的帧，运动估计器自动地估计图像数据的各个帧之间的相对移动。当传感器围绕图像数据阵列的方位角旋转时，目标的特征保持在跟踪阵列的图像平面内。使用跟踪阵列的图像平面中的这些特征的运动来估计针对三维重建所需的运动。类似的技术估计图像平面内的运动以产生扩展的视场。

10. 发明授权

US6102865A Multiple ultrasound image registration system, method and transducer 有权
公开(公告)号：US6102865A
公开(公告)日：2000-08-15
申请号：US346090
申请日：1999-07-01
申请人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
发明人： John A. Hossack , John W. Sliwa, Jr. , Samuel H. Maslak , Edward A. Gardner , Gregory L. Holley , David J. Napolitano
IPC分类号： A61B8/00 , G01S7/52 , G01S15/66 , G01S15/87 , G01S15/89 , G06T7/20 , A61B8/14
CPC分类号： A61B8/145 , A61B8/483 , G01S15/8934 , G01S15/8979 , G01S15/8993 , G01S7/52085 , G06T7/2033 , G01S15/66 , G01S15/87 , G01S7/52034 , G01S7/52065 , G01S7/52071
摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.

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