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1. 发明申请

US20170258890A1 GENETICALLY STABLE REPLICATION COMPETENT SENDAI VIRUS VECTOR(S) CONTAINING AND EXPRESSING OPTIMIZED HIV GENES 审中-公开
公开(公告)号：US20170258890A1
公开(公告)日：2017-09-14
申请号：US15498554
申请日：2017-04-27
申请人： John Coleman , Josephine Helena Cox , Arban Domi , Hiroto Hara , Takashi Hironaka , Makoto Inoue , Dagna Skoog Laufer , Angela Grazia Lombardo , Christopher L. Parks , Eddy Sayeed , Maoli Yuan , Xinsheng Zhang
发明人： John Coleman , Josephine Helena Cox , Arban Domi , Hiroto Hara , Takashi Hironaka , Makoto Inoue , Dagna Skoog Laufer , Angela Grazia Lombardo , Christopher L. Parks , Eddy Sayeed , Maoli Yuan , Xinsheng Zhang
IPC分类号： A61K39/21 , C07K14/005 , C12N15/86 , C12N7/00
CPC分类号： A61K39/21 , A61K39/12 , A61K2039/5256 , A61K2039/53 , A61K2039/543 , A61K2039/545 , A61K2039/55511 , A61K2039/55555 , A61K2039/57 , A61K2039/575 , A61K2039/70 , C07K14/005 , C12N7/00 , C12N15/86 , C12N2740/16034 , C12N2740/16134 , C12N2740/16234 , C12N2740/16271 , C12N2740/16334 , C12N2760/18443 , C12N2760/18843 , C12N2760/18871 , C12N2760/20243
摘要： The present invention relates to genetically stable replication competent Sendai virus vector(s) containing optimized HIV genes, methods for making the same and cell substrates qualified for vaccine production which may comprise genetically stable replication competent Sendai virus vector(s) containing optimized HIV genes.

2. 发明申请

US20170258891A1 OPTIMIZED HIV ENVELOPE GENE AND EXPRESSION THEREOF 审中-公开
公开(公告)号：US20170258891A1
公开(公告)日：2017-09-14
申请号：US15498556
申请日：2017-04-27
申请人： Christopher L. Parks , Maoli Yuan , Xinsheng Zhang , Aaron Wilson , Angela Grazia Lombardo , Eddy Sayeed , Josephine Helena Cox , Takashi Hironaka , Makoto Inoue , Hiroto Hara
发明人： Christopher L. Parks , Maoli Yuan , Xinsheng Zhang , Aaron Wilson , Angela Grazia Lombardo , Eddy Sayeed , Josephine Helena Cox , Takashi Hironaka , Makoto Inoue , Hiroto Hara
IPC分类号： A61K39/21 , C12N15/86 , C12N7/00
CPC分类号： A61K39/21 , A61K39/12 , A61K2039/5256 , A61K2039/53 , A61K2039/543 , A61K2039/545 , A61K2039/55511 , A61K2039/55555 , A61K2039/57 , A61K2039/575 , A61K2039/70 , C07K14/005 , C12N7/00 , C12N15/86 , C12N2740/16034 , C12N2740/16134 , C12N2740/16234 , C12N2740/16271 , C12N2740/16334 , C12N2760/18443 , C12N2760/18843 , C12N2760/18871 , C12N2760/20243
摘要： The present invention relates to a vector(s) containing and expressing an optimized HIV EnvF gene, methods for making the same and cell substrates qualified for vaccine production which may comprise vector(s) containing optimized HIV genes.

3. 发明申请

US20050191617A1 Pramyxovirusl vectors encoding antibody and utilization thereof 审中-公开
标题翻译：编码抗体的帕拉莫病毒载体及其利用
公开(公告)号：US20050191617A1
公开(公告)日：2005-09-01
申请号：US10516429
申请日：2003-06-03
申请人： Makoto Inoue , Mamoru Hasegawa , Takashi Hironaka
发明人： Makoto Inoue , Mamoru Hasegawa , Takashi Hironaka
IPC分类号： A61K48/00 , A61P19/08 , A61P25/00 , A61P37/06 , A61P43/00 , C07K16/00 , C07K16/22 , C07K16/28 , C12N15/86 , C12Q1/70 , C07K16/08 , C12N5/06 , C12N7/00
CPC分类号： C07K16/00 , A61K48/00 , A61K48/005 , C07K16/22 , C07K16/2818 , C07K2317/55 , C07K2317/76 , C12N15/86 , C12N2760/18843 , C12N2760/18871 , C12N2800/30
摘要： The present invention provides paramyxoviral vectors expressing polypeptides that comprise antibody variable regions. A vector of this invention, encoding antibody variable regions of the H and L chains, succeeded in simultaneously expressing these antibody chains to form a Fab, and further succeeded in expressing a single chain antibody at a high level. The vectors of this invention are suitable as vectors for gene therapy, to be administered in vivo or ex vivo to living bodies. In particular, vectors expressing antibody fragments against neurite outgrowth inhibitors are useful in gene therapies for nerve lesions. Further, vectors of this invention that express antibodies which inhibit immune activation signal transduction enable the long-term expression of genes from the vectors.
摘要翻译：本发明提供了表达包含抗体可变区的多肽的副粘病毒载体。编码H和L链的抗体可变区的本发明的载体成功地同时表达这些抗体链以形成Fab，并且进一步以高水平表达单链抗体。本发明的载体适合作为用于基因治疗的载体，在体内或离体给予生物体。特别地，表达针对神经突增生抑制剂的抗体片段的载体可用于神经损伤的基因治疗。此外，本发明的表达抑制免疫激活信号转导的抗体的载体能够从载体中长期表达基因。

4. 发明申请

US20110271296A1 AUTOMATICALLY RECONFIGURABLE MULTIMEDIA SYSTEM WITH INTERCHANGEABLE PERSONALITY ADAPTERS 有权
标题翻译：具有交互性个人适配器的自动可重新配置的多媒体系统
公开(公告)号：US20110271296A1
公开(公告)日：2011-11-03
申请号：US13182592
申请日：2011-07-14
申请人： Edgar Tu , David Boyden , Takashi Hironaka , Thomas Dawson , George Williams , Ludovic Douillet , Rajesh Rao , Peter Rae Shintani , Djung Nguyen , Milton Frazier , Ian Charles Matthews , Behram Mario Dacosta , Robert Hardacker , Nicholas James Colsey , Mark Hanson , Jason R. Meerbergen , Leo Mark Pedlow , Rolf Toft
发明人： Edgar Tu , David Boyden , Takashi Hironaka , Thomas Dawson , George Williams , Ludovic Douillet , Rajesh Rao , Peter Rae Shintani , Djung Nguyen , Milton Frazier , Ian Charles Matthews , Behram Mario Dacosta , Robert Hardacker , Nicholas James Colsey , Mark Hanson , Jason R. Meerbergen , Leo Mark Pedlow , Rolf Toft
IPC分类号： H04N7/16
CPC分类号： H04N5/46 , H04N5/44543 , H04N5/775 , H04N5/781 , H04N5/85 , H04N5/907 , H04N7/163 , H04N7/1675 , H04N21/4184 , H04N21/436 , H04N21/43615 , H04N21/4367 , H04N21/4532 , H04N21/475
摘要： A TV-set is equipped with HDMI and USB connections that allow it to display and run audio-video content from a variety of conventional consumer devices. The TV-set is further equipped to provide a secure HDMI-USB interface that will allow the transfer of licensed high definition content and Internet subscriber services. Such secure HDMI-USB interface also enables a selection of proprietary application modules to be attached. Downloadable user interface templates, much like XML style sheets, are rendered to a user interface displayed on the screen. These are associated with corresponding thumbnails and URI's that allow a user to surf through lists and catalogs of materials, and then to play them in the appropriate formats and provide the machine with a customized controller. A remote commander is simplified, yet expanded to control all the attached devices through interactions with the user interface. The functions of the remote commander's keys change depending on where the user is navigating and what device is being controlled, similar to so-called soft-keys.
摘要翻译：电视机配有HDMI和USB连接，可以显示和运行各种常规消费类设备的音视频内容。电视机还具备提供安全的HDMI-USB接口，允许传输许可的高分辨率内容和互联网用户服务。这种安全的HDMI-USB接口还可以选择要附加的专有应用模块。可下载的用户界面模板，非常像XML样式表，被渲染到屏幕上显示的用户界面。这些与相应的缩略图和URI相关联，允许用户浏览材料的列表和目录，然后以适当的格式播放它们，并向机器提供定制的控制器。远程指挥官被简化，但扩展为通过与用户界面的交互来控制所有连接的设备。遥控器的键的功能根据用户导航的位置以及正在控制的设备而改变，类似于所谓的软键。

5. 发明授权

US07996869B2 Automatically reconfigurable multimedia system with interchangeable personality adapters 有权
标题翻译：具有可互换个性适配器的自动可重新配置的多媒体系统
公开(公告)号：US07996869B2
公开(公告)日：2011-08-09
申请号：US11840189
申请日：2007-08-16
申请人： Edgar Tu , David Boyden , Takashi Hironaka , Thomas Dawson , George Williams , Ludovic Douillet , Rajesh Rao , Peter Rae Shintani , Djung Nguyen , Milton Frazier , Ian Charles Matthews , Behram Mario Dacosta , Robert Hardacker , Nicholas James Colsey , Mark Hanson , Jason R. Meerbergen , Leo Mark Pedlow , Rolf Toft
发明人： Edgar Tu , David Boyden , Takashi Hironaka , Thomas Dawson , George Williams , Ludovic Douillet , Rajesh Rao , Peter Rae Shintani , Djung Nguyen , Milton Frazier , Ian Charles Matthews , Behram Mario Dacosta , Robert Hardacker , Nicholas James Colsey , Mark Hanson , Jason R. Meerbergen , Leo Mark Pedlow , Rolf Toft
IPC分类号： H04N5/445 , H04N5/44
CPC分类号： H04N5/46 , H04N5/44543 , H04N5/775 , H04N5/781 , H04N5/85 , H04N5/907 , H04N7/163 , H04N7/1675 , H04N21/4184 , H04N21/436 , H04N21/43615 , H04N21/4367 , H04N21/4532 , H04N21/475
摘要： A TV-set is equipped with HDMI and USB connections that allow it to display and run audio-video content from a variety of conventional consumer devices. The TV-set is further equipped to provide a secure HDMI-USB interface that will allow the transfer of licensed high definition content and Internet subscriber services. Such secure HDMI-USB interface also enables a selection of proprietary application modules to be attached. Downloadable user interface templates, much like XML style sheets, are rendered to a user interface displayed on the screen. These are associated with corresponding thumbnails and URI's that allow a user to surf through lists and catalogs of materials, and then to play them in the appropriate formats and provide the machine with a customized controller. A remote commander is simplified, yet expanded to control all the attached devices through interactions with the user interface. The functions of the remote commander's keys change depending on where the user is navigating and what device is being controlled, similar to so-called soft-keys.
摘要翻译：电视机配有HDMI和USB连接，可以显示和运行各种常规消费类设备的音视频内容。电视机还具备提供安全的HDMI-USB接口，允许传输许可的高分辨率内容和互联网用户服务。这种安全的HDMI-USB接口还可以选择要附加的专有应用模块。可下载的用户界面模板，非常像XML样式表，被渲染到屏幕上显示的用户界面。这些与相应的缩略图和URI相关联，允许用户浏览材料的列表和目录，然后以适当的格式播放它们，并向机器提供定制的控制器。远程指挥官被简化，但扩展为通过与用户界面的交互来控制所有连接的设备。遥控器的键的功能根据用户导航的位置以及正在控制的设备而改变，类似于所谓的软键。

6. 发明申请

US20080235736A1 System and method for dynamic updating of TV menu 审中-公开
标题翻译：电视菜单动态更新的系统和方法
公开(公告)号：US20080235736A1
公开(公告)日：2008-09-25
申请号：US11726558
申请日：2007-03-22
申请人： Thomas Patrick Dawson , Ludovic Douillet , Takashi Hironaka , Rajesh Kechal Rao , George Edward Williams
发明人： Thomas Patrick Dawson , Ludovic Douillet , Takashi Hironaka , Rajesh Kechal Rao , George Edward Williams
IPC分类号： H04N7/025
CPC分类号： H04N5/44543 , H04N21/4104 , H04N21/4314 , H04N21/43632 , H04N21/4622 , H04N21/482 , H04N21/488
摘要： When a new device such as a set-back box (SBB) connects to a TV, the menu of the TV is dynamically updated with an icon and an application identification associated with the new device, so that a viewer can select the new device from the menu.
摘要翻译：当诸如机顶盒（SBB）的新设备连接到TV时，电视的菜单被动态地更新为与新设备相关联的图标和应用标识，使得观看者可以从菜单。

7. 发明授权

US08544047B2 Automatically reconfigurable multimedia system with interchangeable personality adapters 有权
标题翻译：具有可互换个性适配器的自动可重新配置的多媒体系统
公开(公告)号：US08544047B2
公开(公告)日：2013-09-24
申请号：US13182592
申请日：2011-07-14
申请人： Edgar Tu , David Boyden , Takashi Hironaka , Thomas Dawson , George Williams , Ludovic Douillet , Rajesh Rao , Peter Rae Shintani , Djung Nguyen , Milton Frazier , Ian Charles Matthews , Behram Mario Dacosta , Robert Hardacker , Nicholas James Colsey , Mark Hanson , Jason R. Meerbergen , Leo Mark Pedlow , Rolf Toft
发明人： Edgar Tu , David Boyden , Takashi Hironaka , Thomas Dawson , George Williams , Ludovic Douillet , Rajesh Rao , Peter Rae Shintani , Djung Nguyen , Milton Frazier , Ian Charles Matthews , Behram Mario Dacosta , Robert Hardacker , Nicholas James Colsey , Mark Hanson , Jason R. Meerbergen , Leo Mark Pedlow , Rolf Toft
IPC分类号： H04N7/18 , H04N7/16
CPC分类号： H04N5/46 , H04N5/44543 , H04N5/775 , H04N5/781 , H04N5/85 , H04N5/907 , H04N7/163 , H04N7/1675 , H04N21/4184 , H04N21/436 , H04N21/43615 , H04N21/4367 , H04N21/4532 , H04N21/475
摘要： A TV-set is equipped with HDMI and USB connections that allow it to display and run audio-video content from a variety of conventional consumer devices. The TV-set is further equipped to provide a secure HDMI-USB interface that will allow the transfer of licensed high definition content and Internet subscriber services. Such secure HDMI-USB interface also enables a selection of proprietary application modules to be attached. Downloadable user interface templates, much like XML style sheets, are rendered to a user interface displayed on the screen. These are associated with corresponding thumbnails and URI's that allow a user to surf through lists and catalogs of materials, and then to play them in the appropriate formats and provide the machine with a customized controller. A remote commander is simplified, yet expanded to control all the attached devices through interactions with the user interface. The functions of the remote commander's keys change depending on where the user is navigating and what device is being controlled, similar to so-called soft-keys.
摘要翻译：电视机配有HDMI和USB连接，可以显示和运行各种常规消费类设备的音视频内容。电视机还具备提供安全的HDMI-USB接口，允许传输许可的高分辨率内容和互联网用户服务。这种安全的HDMI-USB接口还可以选择要附加的专有应用模块。可下载的用户界面模板，非常像XML样式表，被渲染到屏幕上显示的用户界面。这些与相应的缩略图和URI相关联，允许用户浏览材料的列表和目录，然后以适当的格式播放它们，并向机器提供定制的控制器。远程指挥官被简化，但扩展为通过与用户界面的交互来控制所有连接的设备。遥控器的键的功能根据用户导航的位置以及正在控制的设备而改变，类似于所谓的软键。

8. 发明授权

US08429713B2 Method and apparatus to speed transmission of CEC commands 失效
标题翻译：加速CEC命令传输的方法和装置
公开(公告)号：US08429713B2
公开(公告)日：2013-04-23
申请号：US11695359
申请日：2007-04-02
申请人： Brant Candelore , Aravind Asam , Peter R Shintani , Robert Blanchard , Takashi Hironaka
发明人： Brant Candelore , Aravind Asam , Peter R Shintani , Robert Blanchard , Takashi Hironaka
IPC分类号： H04L29/06
CPC分类号： H04N21/43615 , H04N21/4363 , H04N21/4432
摘要： A method and structure for establishing faster transmission of Consumer Electronic Control (CEC) commands between first and second HDMI-compatible devices. The first and second devices may transmit CEC commands via a shared alternate interface, a signaling path distinct from a standard HDMI CEC interface between the first and second devices. Authentication may furthermore be performed prior to use of the alternate interface to confirm that the communication is authorized.
摘要翻译：用于在第一和第二HDMI兼容设备之间建立消费电子控制（CEC）命令的更快传输的方法和结构。第一和第二设备可以经由共享的备用接口（不同于第一和第二设备之间的标准HDMI CEC接口的信令路径）发送CEC命令。此外可以在使用备用接口以确认通信被授权之前进行认证。

9. 发明申请

US20120096104A1 ELECTRONIC DEVICE WITH CUSTOMIZABLE EMBEDDED SOFTWARE AND METHODS THEREFOR 有权
标题翻译：具有可自定义嵌入式软件的电子设备及其方法
公开(公告)号：US20120096104A1
公开(公告)日：2012-04-19
申请号：US12903869
申请日：2010-10-13
申请人： Takashi Hironaka
发明人： Takashi Hironaka
IPC分类号： G06F15/167
CPC分类号： G06F8/654 , H04N21/4424 , H04N21/443 , H04N21/472 , H04N21/6582 , H04N21/8166
摘要： An electronic device comprising: a central processing unit; memory in data communication with the central processing unit; a network connector in data communication with the central processing unit; a firmware image stored in a compressed format within the memory, wherein the firmware image includes a plurality of software components; and an update agent stored within the memory and configured to provide a list of software components for communication out the network connector, wherein the electronic device is configured to communicate the list of software components out the network connector and receive a modified firmware image in a compressed format that includes at least one additional software component.
摘要翻译：一种电子设备，包括：中央处理单元; 与中央处理单元进行数据通信的存储器; 与中央处理单元进行数据通信的网络连接器; 在所述存储器内以压缩格式存储的固件图像，其中所述固件图像包括多个软件组件; 以及存储在所述存储器内并被配置为提供用于从所述网络连接器通信的软件组件的列表的更新代理，其中所述电子设备被配置为将所述软件组件的列表传送出所述网络连接器，并且在压缩包括至少一个附加软件组件的格式。

10. 发明申请

US20090219442A1 USING NETWORK SERVER TO ESTABLISH TV SETTING 失效
标题翻译：使用网络服务器建立电视机设置
公开(公告)号：US20090219442A1
公开(公告)日：2009-09-03
申请号：US12040262
申请日：2008-02-29
申请人： Takashi Hironaka , Max Wu
发明人： Takashi Hironaka , Max Wu
IPC分类号： H04N5/57
CPC分类号： H04N5/58 , H04N7/17318 , H04N21/42202 , H04N21/4854 , H04N21/6547 , H04N21/6582
摘要： TV settings such as brightness can be established by sending from a TV signals from an ambient light sensor to a network server, with the network server establishing settings such as brightness in response for a program being played on the TV.
摘要翻译：可以通过从TV环境光传感器向网络服务器发送电视信号来建立诸如亮度的电视设置，网络服务器建立诸如响应于在TV上播放的节目的亮度的设置。

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