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    • 1. 发明授权
    • Method of manufacturing hydrogel dressings
    • 制造水凝胶敷料的方法
    • US4871490A
    • 1989-10-03
    • US140150
    • 1987-12-30
    • Janusz RosiakAnna Rucinska-RybusWladyslaw Pekala
    • Janusz RosiakAnna Rucinska-RybusWladyslaw Pekala
    • A61L26/00C08F2/46
    • A61L26/008A61L26/0052A61L26/0071Y10S602/90
    • A method of manufacturing hydrogel dressings from synthetic and natural polymers by polymerization and cross-linking involves pouring aqueous solutions of synthetic polymers, such as polyacrylamide and polyvinylpyrolidone, their monomers or their mixtures, natural polymers, such as gelatine or agar, or their mixtures and, possibly, plasticizing agents, such as poly/ethylene glycol/, poly/propylene glycol/ and silicone oils, of the following composition: 2-20 percent by weight of synthetic polymers, not more than 5 percent by weight of natural polymers, not less than 75 percent by weight of distilled water and 1-3 percent by weight of plasticizing agent, into a mould imparting a shape to the dressing, tightly closing in that mould and subjecting to an ionizing radiation dose not smaller than 25 kGy.
    • 通过聚合和交联从合成和天然聚合物制备水凝胶敷料的方法涉及将合成聚合物如聚丙烯酰胺和聚乙烯吡咯烷酮,其单体或其混合物的水溶液倒入天然聚合物如明胶或琼脂或其混合物中, ,可能的是具有以下组成的增塑剂如聚乙二醇/聚丙二醇/硅油:2-20重量%的合成聚合物,不超过5重量%的天然聚合物,不是 小于75重量%的蒸馏水和1-3重量%的增塑剂加入到赋形剂中赋予形状的模具中,在该模具中紧密封闭并进行不小于25kGy的电离辐射。