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1. 发明授权

US06373384B1 Inflatable security device 失效
标题翻译：充气安全装置
公开(公告)号：US06373384B1
公开(公告)日：2002-04-16
申请号：US09551308
申请日：2000-04-18
申请人： Gary William Ferguson , Branko Palcic
发明人： Gary William Ferguson , Branko Palcic
IPC分类号： G08B2100
CPC分类号： G08B5/002 , A63H2027/1033 , G08B15/02
摘要： A deterrent device comprises a portable container having a cavity disposed therein and an actuator mechanism disposed within the cavity. An inflatable deterrent extends outwardly from the actuator mechanism, the inflatable deterrent is substantially contained within the cavity in a non-operative configuration. The actuator mechanism is activated by an operator to attain an operative configuration in which the actuator mechanism inflates the inflatable deterrent outwardly from the container, an assailant being deterred by the inflated inflatable deterrent.
摘要翻译：威慑装置包括具有设置在其中的空腔的便携式容器和设置在空腔内的致动器机构。可膨胀的阻力从致动器机构向外延伸，可膨胀的阻力基本上以非操作构型包含在空腔内。致动器机构由操作者启动以获得操作构造，其中致动器机构将充气阻力从容器向外膨胀，攻击者被充气的充气阻力阻止。

2. 发明授权

US06972006B2 Syringe device with resistive ridges and methods of use 失效
标题翻译：具有电阻脊的注射器和使用方法
公开(公告)号：US06972006B2
公开(公告)日：2005-12-06
申请号：US10246600
申请日：2002-09-18
申请人： Gary William Ferguson
发明人： Gary William Ferguson
IPC分类号： A61M5/31 , A61M5/315 , A61M5/00
CPC分类号： A61M5/3129 , A61M2005/31506 , A61M2205/582
摘要： A syringe device incorporating ridges that cause resistive changes to the movement of the syringe gasket or plunger, thereby providing user feedback as to the position and speed of plunger movement. Such user feedback may be useful in stressful situations, under poor lighting conditions or in other unfavorable circumstances. Additionally, in certain embodiments these ridges may aid in accurate dispension or allow the syringe to derive additional functionality, such as performing as a vacuum source. Ridges can be protrusions such as tabs, bubbles or continuous rings for single or repeated use or these ridges may be formed as indentations. Ridges may be formed in patterns, in various sizes and shapes or these ridges may be mixed and matched as required or desired. Ridges may also be formed from a soluble material and the resistive change may itself provide indication that the material has been substantially dissolved and dispensed. In some embodiments these ridges are formed primarily within the barrel portion of the syringe. In other embodiments these ridges may be formed on the plunger stem of the syringe. Ridges may be constructed to provide one type of resistive change during the aspiration stroke and a different resistive change to motion in the opposite direction.
摘要翻译：一种注射器装置，其包含引起对注射器垫圈或柱塞的移动的电阻变化的脊，由此提供关于柱塞移动的位置和速度的用户反馈。这种用户反馈可能在紧张情况下，在不良照明条件下或其他不利情况下有用。另外，在某些实施例中，这些脊可以有助于准确地分配，或允许注射器导出附加的功能，诸如作为真空源执行。脊可以是用于单次或重复使用的突起，例如突片，气泡或连续环，或者这些脊可以形成为凹陷。脊可以形成为各种尺寸和形状的图案，或者这些脊可以根据需要或需要进行混合和匹配。脊也可以由可溶性材料形成，并且电阻变化本身可以提供材料已被基本上溶解并分配的指示。在一些实施例中，这些脊主要形成在注射器的筒部内。在其它实施例中，这些脊可以形成在注射器的柱塞杆上。脊可以被构造成在抽吸冲程期间提供一种类型的电阻变化，并且在相反方向上提供不同的电阻变化。

3. 发明授权

US06820741B2 Disc media and storage and retrieval system 失效
公开(公告)号：US06820741B2
公开(公告)日：2004-11-23
申请号：US10339266
申请日：2003-01-09
申请人： Gary William Ferguson , Jayson Darek Eppler
发明人： Gary William Ferguson , Jayson Darek Eppler
IPC分类号： B65D8557
CPC分类号： G11B23/0021 , G11B33/045 , G11B33/0477
摘要： The present invention is a disc media storage and retrieval system for safely and efficiently storing and conveniently retrieving specific disc media from a plurality of disc media stacked on a central column or spindle. Modified disc media are rotationally aligned on the spindle using corresponding alignment protrusion(s) formed on the spindle and notch(es) on the inner chuck hole of the disc. Accordingly, disc media is further modified with the addition of indexing notches on the outer circumference of the disk, such that each disc within the system is provided a unique notched-index. The aligned stack is protected by a cover member that forms a disc lifting device. A disc of interest is indexed and retrieved from the stack by rotating the cover member relative to the disc stack thereby aligning the disc notch-index with the lifting device. When the cover member is raised, the lifting device separates the stack at the disc of interest. These innovations and modifications to the disc media provide improvements in disc storage and retrieval over existing spindle-type disc media storage systems.

4. 发明授权

US07211225B2 Filter devices for depositing material and density gradients of material from sample suspension 失效
标题翻译：用于沉积材料的过滤装置和来自样品悬浮液的材料的密度梯度
公开(公告)号：US07211225B2
公开(公告)日：2007-05-01
申请号：US10228353
申请日：2002-08-26
申请人： Gary William Ferguson , Marija Us-Krasovec , Margareta Flezar , Mario Zganec , Jaka Lavrencak , Branko M. Palcic
发明人： Gary William Ferguson , Marija Us-Krasovec , Margareta Flezar , Mario Zganec , Jaka Lavrencak , Branko M. Palcic
IPC分类号： G01N30/00
CPC分类号： G01N1/18 , G01N1/2813 , G01N1/4077 , G01N15/0272 , Y10T436/25 , Y10T436/25375 , Y10T436/255
摘要： The present invention provides a simple, inexpensive apparatus for and method of capturing biological or other material from sample suspensions on a collection surface and for depositing captured material on a receiving surface, such as a microscope slide, for observation and analysis. Accordingly, cytological material may be deposited in near mono-layers for the detection of disease. In one embodiment of the present invention, density gradients of material are captured and deposited, thus providing a desired range of concentrations for examination. In another embodiment multiple depositions or multiple slides may be made from the same sample suspension. The method and apparatus to exploit this new method are both presented for various applications. The dimensions of material captured and deposited may be controlled and used in conjunction with microscope slides that confine material to specific regions of interest.
摘要翻译：本发明提供了一种用于从采集表面上的样品悬浮液捕获生物或其他材料并用于将捕获的材料沉积在诸如显微镜载玻片的接收表面上的简单且便宜的装置，用于观察和分析。因此，细胞学材料可以沉积在近乎单层以检测疾病。在本发明的一个实施例中，材料的密度梯度被捕获并沉积，从而提供期望的浓度范围用于检查。在另一个实施方案中，可以从相同的样品悬浮液制备多个沉积物或多个载玻片。利用这种新方法的方法和装置都是针对各种应用提出的。捕获和沉积的材料的尺寸可以被控制并与将材料限制在特定感兴趣区域的显微镜载玻片一起使用。

5. 发明授权

US07153691B2 Method of identifying and assessing DNA euchromatin in biological cells for detecting disease, monitoring wellness, assessing bio-activity, and screening pharmacological agents 失效
标题翻译：识别和评估生物细胞中DNA嗜铬蛋白的方法，用于检测疾病，监测健康，评估生物活性和筛选药物代谢
公开(公告)号：US07153691B2
公开(公告)日：2006-12-26
申请号：US10293609
申请日：2002-11-13
申请人： Gary William Ferguson
发明人： Gary William Ferguson
IPC分类号： G01N33/52
CPC分类号： C12Q1/6841 , C12Q1/68
摘要： The present invention is a method of identifying and assessing DNA euchromatin in biological cells. The amount and/or distribution of DNA euchromatin generally relates to RNA/protein synthesis, which may change in certain conditions, such as disease, and/or cellular response to environmental and/or chemical agents. The present invention detects the potential presence of disease by assessing DNA euchromatin in ostensibly normal cells and similarly provides means to monitor and assess treatment response. The present invention may also be used to assess how application (or removal) of influences, such as environment, radiation, chemical agents, medications, herbs, vitamins, etc., interact to effect cells, establishing uses in monitoring wellness and pharmacological screening. Additional uses include assessing age related disorders, allergies, infections, Alzheimer's disease, ‘Time of Death’, chronic fatigue syndrome, etc. The method may be advantageously applied to biological cells including micro-organisms, plants, animals, or cultured cells, alone or in conjunction with other markers.
摘要翻译：本发明是鉴定和评估生物细胞中DNA复合物的方法。 DNA泛素的量和/或分布通常涉及RNA /蛋白质合成，其可在某些条件下变化，例如疾病和/或细胞对环境和/或化学试剂的反应。本发明通过在表面上正常细胞中评估DNA嗜铬蛋白来检测潜在的疾病存在，并且类似地提供监测和评估治疗反应的手段。本发明还可以用于评估如环境，辐射，化学试剂，药物，草药，维生素等的影响的应用（或去除）如何相互影响细胞，建立用于监测健康和药理学筛选的用途。额外的用途包括评估年龄相关疾病，过敏症，感染，阿尔茨海默病，“死亡时间”，慢性疲劳综合征等。该方法可有利地应用于包括微生物，植物，动物或培养细胞在内的生物细胞或与其他标记结合使用。

6. 发明授权

US06905594B2 Filter apparatus and methods to capture a desired amount of material from a sample suspension for monolayer deposition, analysis or other uses 失效
标题翻译：用于从用于单层沉积，分析或其它用途的样品悬浮液中捕获所需量的材料的过滤装置和方法
公开(公告)号：US06905594B2
公开(公告)日：2005-06-14
申请号：US10269220
申请日：2002-10-11
申请人： Gary William Ferguson
发明人： Gary William Ferguson
IPC分类号： B01D61/22 , G01N1/28 , G01N15/06 , B01L11/00
CPC分类号： G01N15/0618 , B01D61/22 , G01N1/2813 , G01N1/4077 , Y10T436/25375
摘要： The present invention is a filter apparatus with methods to capture a desired amount of material suspended in a liquid or gas for monolayer deposition, analysis or other uses. Novel filter devices are employed to capture material which may be used for the purification or enrichment of various sample constituents or captured material may be observed or analyzed. Alternatively, particulate material may be used as a transport mechanism for proteins or chemicals which in turn may be assessed or used. The filter device employs sensors to sense pressure and adjust, halt or otherwise control sample flow. The pressure sensor essentially monitors the flow rate of sample suspension through a filter, typically responding at a predetermined pressure associated with capture of a desired amount of material on the filter. A separate valve or valve integrated with pressure sensing provides a means to adjust sample flow. Typically, pressure is used to cause the sample suspension to flow through the filter, which is preferably a membrane filter for monolayer deposition. In some embodiments a novel syringe provides this pressure, functioning as a vacuum source. The filter apparatus may be further automated to process a plurality of samples, simultaneously.
摘要翻译：本发明是一种具有捕获悬浮在液体或气体中用于单层沉积，分析或其它用途的所需量的材料的方法的过滤装置。采用新颖的过滤装置来捕获可用于各种样品组分的纯化或富集的材料，或者可以观察或分析捕获的材料。或者，颗粒材料可以用作蛋白质或化学品的运输机制，其又可以被评估或使用。过滤装置使用传感器来感测压力并调节，停止或以其他方式控制样品流。压力传感器基本上监测通过过滤器的样品悬浮液的流速，通常在与在过滤器上捕获所需量的材料相关联的预定压力下进行响应。与压力传感器集成的单独的阀门或阀门提供了一种调节样品流量的方法。通常，使用压力使样品悬浮液流过过滤器，该过滤器优选是用于单层沉积的膜过滤器。在一些实施方案中，新颖的注射器提供这种作为真空源的压力。过滤装置可以进一步自动化以同时处理多个样品。

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