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1. 发明申请

US20050025179A1 Distributing and balancing traffic flow in a virtual gateway 有权
标题翻译：分布和平衡虚拟网关中的流量
公开(公告)号：US20050025179A1
公开(公告)日：2005-02-03
申请号：US10632704
申请日：2003-07-31
申请人： Douglas McLaggan , Ian Wilson , Mark Denny , Rick Williams
发明人： Douglas McLaggan , Ian Wilson , Mark Denny , Rick Williams
IPC分类号： H04J3/16 , H04L12/56
CPC分类号： H04L45/00 , H04L45/28 , H04L45/38 , H04L45/586 , H04L47/10 , H04L47/125
摘要： The distribution of traffic flows in a load-sharing redundancy group that includes a first gateway device and a second gateway device includes assigning a first set of forwarding addresses to the first gateway device and a second set of forwarding addresses to the second gateway device. The redundancy group distributes forwarding addresses to hosts which in turn use the distributed forwarding addresses to send packets to the redundancy group. The traffic flow for each of the assigned forwarding addresses is measured and may be compared to a target traffic flow. The traffic flow is adjusted to close in on the target traffic flow. Adjustment of the traffic flow can be accomplished either by changing the existing measured traffic flow by re-assigning a forwarding address originally assigned to one gateway device to a different gateway device or by altering future distribution of forwarding addresses so that additional traffic is sent to one or more forwarding addresses having lower measured traffic. The gateway devices can be routers using virtual MAC addresses as forwarding addresses. The redundancy group may also be configured to provide failover services in the event that one of the gateway devices ceases operation.
摘要翻译：在包括第一网关设备和第二网关设备的负载共享冗余组中的流量分配包括：向第一网关设备分配第一组转发地址，向第二网关设备分配第二组转发地址。冗余组将转发地址分配给主机，主机依次使用分布式转发地址向冗余组发送数据包。测量每个分配的转发地址的流量，并将其与目标业务流进行比较。交通流量被调整为关闭目标交通流量。可以通过将原始分配给一个网关设备的转发地址重新分配给不同的网关设备或通过改变转发地址的将来分配来改变现有的测量业务流来实现流量的调整，从而将额外的流量发送到一个或更多的具有较低测量业务量的转发地址。网关设备可以是使用虚拟MAC地址作为转发地址的路由器。冗余组还可以被配置为在其中一个网关设备停止操作的情况下提供故障转移服务。

2. 发明申请

US20170320921A1 PROTEIN M RELATED IMMUNOGLOBULIN-BINDING POLYPEPTIDES 审中-公开
公开(公告)号：US20170320921A1
公开(公告)日：2017-11-09
申请号：US15115773
申请日：2015-02-02
申请人： Rajesh GROVER , Richard LERNER , Ian WILSON , Xueyong ZHU , THE SCRIPPS RESEARCH INSTITUTE
发明人： Rajesh Grover , Richard Lerner , Ian Wilson , Xueyong Zhu
IPC分类号： C07K14/30 , C07K1/22 , C07K16/00
CPC分类号： C07K14/30 , C07K1/22 , C07K16/00 , C07K2319/00
摘要： The invention relates to a group of isolated polypeptides and derivatives that can bind genetically to immunoglobulins or antibodies. The invention also relates to industrial and other applications of these molecules, e.g., antibody purifications.

3. 发明授权

US08596930B2 Degradable erosion control barrier 有权
标题翻译：可降解侵蚀控制屏障
公开(公告)号：US08596930B2
公开(公告)日：2013-12-03
申请号：US11746869
申请日：2007-05-10
申请人： Walter van Woudenberg , Ian Wilson
发明人： Walter van Woudenberg , Ian Wilson
IPC分类号： E02D17/20
CPC分类号： E02D17/202
摘要： An erosion control barrier for installation in a drainage path in a service environment. The erosion control barrier includes a unitary permeable sheet which is bent along a longitudinal axis to provide an upslope side, a downslope side and a longitudinally extending apex. The permeable sheet is constructed of a degradable material so that the erosion control barrier has a design service life in the service environment and a design material life in the service environment. The design material life is longer than the design service life. The permeable sheet is designed to be sufficiently transversely stiff and resilient during the design service life to enable the erosion control barrier to be self-supporting. The permeable sheet is designed to substantially disintegrate within the design material life.
摘要翻译：用于安装在服务环境中的排水路径中的侵蚀控制屏障。侵蚀控制屏障包括沿着纵向轴线弯曲的单一可渗透片材，以提供上坡面，下坡面和纵向延伸的顶点。可渗透片由可降解材料构成，使得侵蚀控制屏障在使用环境中具有设计使用寿命，并且在使用环境中具有设计材料寿命。设计使用寿命长于设计使用寿命。可渗透片设计成在设计使用寿命期间具有足够的横向刚性和弹性，以使侵蚀控制屏障能够自支撑。可渗透片被设计成在设计材料寿命内基本上分解。

4. 发明授权

US08235656B2 Catenary turbine seal systems 有权
标题翻译：悬链涡轮密封系统
公开(公告)号：US08235656B2
公开(公告)日：2012-08-07
申请号：US12370960
申请日：2009-02-13
申请人： Ian Wilson , Kenneth Black , Josef Scott Cummins
发明人： Ian Wilson , Kenneth Black , Josef Scott Cummins
IPC分类号： F01D25/24
CPC分类号： F01D11/001 , F01D11/005 , F01D11/02 , Y02T50/671
摘要： In one embodiment, a catenary seal structure may be mechanically supported only by two adjacent rotor wheels to isolate a volume between the two adjacent rotor wheels. The catenary seal structure may be annularly disposed about the rotational axis of the adjacent rotor wheels.
摘要翻译：在一个实施例中，悬链密封结构可以仅由两个相邻的转子轮机械地支撑，以隔离两个相邻转子轮之间的体积。悬链密封结构可以围绕相邻的转子轮的旋转轴线环形设置。

5. 发明申请

US20110027178A1 IMAGING THE CENTRAL NERVOUS SYSTEM 审中-公开
标题翻译：成像中央神经系统
公开(公告)号：US20110027178A1
公开(公告)日：2011-02-03
申请号：US12867914
申请日：2009-02-26
申请人： Paul Alexander Jones , Ian Wilson , Veronique Morrison-Iveson , Clare Jones , John Woodcraft , Alex Jackson , Duncan Wynn
发明人： Paul Alexander Jones , Ian Wilson , Veronique Morrison-Iveson , Clare Jones , John Woodcraft , Alex Jackson , Duncan Wynn
IPC分类号： A61K51/04 , C07D417/06 , C07D215/38 , C07D401/06 , A61P25/00 , G21C1/01
CPC分类号： A61K51/0455
摘要： The present invention provides novel compounds which may be used as in vivo imaging agents. The compounds of the invention are useful in a method to image the expression of P2X7 receptors in a subject, as a means to facilitate the diagnosis of a range of disease states.
摘要翻译：本发明提供可用作体内成像剂的新型化合物。本发明的化合物可用于成像受试者中P2X7受体表达的方法，以便于诊断一系列疾病状态。

6. 发明申请

US20080086290A1 Method for modeling task and workload 审中-公开
标题翻译：任务和工作负载建模方法
公开(公告)号：US20080086290A1
公开(公告)日：2008-04-10
申请号：US11906816
申请日：2007-10-04
申请人： Ian Wilson
发明人： Ian Wilson
IPC分类号： G06G7/48 , G06F9/44
CPC分类号： G06F8/20 , G06Q10/06 , G06Q10/0637
摘要： A method for modeling task, activity and workload of various human-implemented processes. The models created by this method may be further evaluated so that improvements can be made to the modeled processes. These improvements in modeled processes may include restructuring the human-implemented aspects of the process to take into account the human's cognitive and physical limitations. The model may also be used to identify the information flow aspects of the human cognitive activities allowing the specification and implementation of changes in the information flow or quality to result in improved human workloads.
摘要翻译：对各种人为执行过程的任务，活动和工作量进行建模的方法。可以进一步评估通过该方法创建的模型，以便可以对建模过程进行改进。模拟过程中的这些改进可能包括重组人类执行的过程方面，以考虑到人的认知和身体限制。该模型还可用于识别人类认知活动的信息流动方面，从而允许规范和实施信息流或质量的变化，从而改善人类工作负荷。

7. 发明申请

US20070213278A1 Arrays with cleavable linkers 审中-公开
标题翻译：具有可切割接头的数组
公开(公告)号：US20070213278A1
公开(公告)日：2007-09-13
申请号：US11645273
申请日：2006-12-22
申请人： Chi-Huey Wong , Dennis Burton , Ian Wilson
发明人： Chi-Huey Wong , Dennis Burton , Ian Wilson
IPC分类号： A61K31/70 , G01N33/53
CPC分类号： G01N33/54353 , A61K31/716 , C07H3/06 , G01N33/56972 , G01N33/56988 , G01N33/57415 , G01N2400/02 , G01N2400/14
摘要： The invention provides arrays of molecules where the molecules (e.g., glycans) are attached to the arrays by cleavable linkers. The invention also provides methods for using these arrays, methods for identifying the structural elements of molecules bound to these arrays by using the cleavable linkers, especially the structural elements that are important for binding to test samples. The invention further provides methods for evaluating whether test samples and test molecules can bind to distinct glycans on the arrays and useful glycans identified using the methods and arrays provided herein.
摘要翻译：本发明提供了分子阵列，其中分子（例如，聚糖）通过可切割接头连接到阵列上。本发明还提供了使用这些阵列的方法，通过使用可切割接头，特别是结合测试样品重要的结构元件来鉴定与这些阵列结合的分子的结构元件的方法。本发明还提供了用于评估测试样品和测试分子是否可以结合阵列上的不同聚糖和使用本文提供的方法和阵列鉴定的有用聚糖的方法。

8. 发明申请

US20090101857A1 VALVE ASSEMBLY 审中-公开
标题翻译：阀组件
公开(公告)号：US20090101857A1
公开(公告)日：2009-04-23
申请号：US12158799
申请日：2006-12-11
申请人： Ian Wilson , David Bailey
发明人： Ian Wilson , David Bailey
IPC分类号： F16K27/07
CPC分类号： F16K27/07
摘要： A valve assembly has a valve housing, an inlet, an outlet and a flow passage extending between the inlet and the outlet. A shut-off valve is mounted on the housing adjacent the inlet and a flow control valve is mounted on the housing adjacent the outlet. By mounting both valves on the same housing, the dimensions of the assembly are reduced.
摘要翻译：阀组件具有阀壳体，入口，出口和在入口和出口之间延伸的流动通道。截止阀安装在与入口相邻的壳体上，流量控制阀安装在邻近出口的壳体上。通过将两个阀安装在同一个外壳上，减小了组件的尺寸。

9. 发明申请

US20070071670A1 Diagnostic imaging agents with mmp inhibitory activity 失效
标题翻译：具有抑制活性的诊断成像剂
公开(公告)号：US20070071670A1
公开(公告)日：2007-03-29
申请号：US10544945
申请日：2004-02-10
申请人： Anthony Storey , Julie Davis , Sally-Ann Ricketts , Marivi Medizabal , Alan Cuthbertson , Joseph Arukwe , Kirsty Heywood , Ian Wilson , Duncan Wynn , Michael Schafers , Bodu Levkau , Stefan Wagner , Hans-Jorg Breyholz , Klaus Kopka
发明人： Anthony Storey , Julie Davis , Sally-Ann Ricketts , Marivi Medizabal , Alan Cuthbertson , Joseph Arukwe , Kirsty Heywood , Ian Wilson , Duncan Wynn , Michael Schafers , Bodu Levkau , Stefan Wagner , Hans-Jorg Breyholz , Klaus Kopka
IPC分类号： A61K51/00 , C07D401/02
CPC分类号： A61K51/0497
摘要： The present invention relates to the field of diagnostic imaging. Specifically, the invention relates to the diagnostic imaging of diseases where specific matrix metalloproteinases are known to be involved. One embodiment of the invention is a compound having matrix metalloproteinase inhibitory activity suitable for diagnostic imaging. Also disclosed in the present invention is a pharmaceutical composition comprising the diagnostic imaging agent of the invention in a form suitable for mammalian administration. The invention furthermore discloses intermediates in the synthesis of the diagnostic imaging agents of the invention and kits for the preparation of the pharmaceutical composition of the invention. The pharmaceutical composition of the invention may be used in the diagnosis of diseases where specific matrix metalloproteinases are known to be involved.
摘要翻译：本发明涉及诊断成像领域。具体地，本发明涉及已知涉及特定基质金属蛋白酶的疾病的诊断成像。本发明的一个实施方案是具有适用于诊断成像的基质金属蛋白酶抑制活性的化合物。本发明还公开了一种药物组合物，其包含适合哺乳动物给药形式的本发明的诊断显像剂。本发明还公开了合成本发明的诊断显像剂的中间体和用于制备本发明的药物组合物的试剂盒。本发明的药物组合物可用于诊断已知涉及特定基质金属蛋白酶的疾病。

10. 发明申请

US20060292075A1 Labelled glutamine and lysine analogues 审中-公开
公开(公告)号：US20060292075A1
公开(公告)日：2006-12-28
申请号：US11410177
申请日：2006-04-24
申请人： Anthony Storey , Marivi Mendizabal , Susan Champion , Alex Gibson , Benedicte Guilbert , Ian Wilson , Peter Knox
发明人： Anthony Storey , Marivi Mendizabal , Susan Champion , Alex Gibson , Benedicte Guilbert , Ian Wilson , Peter Knox
IPC分类号： A61K51/00 , A61K38/12 , A61K38/08 , C07K7/64 , C07K7/08
CPC分类号： A61K49/14 , A61K51/088
摘要： Synthetic analogues of lysine and glutamine are provided which function as substrates for the fibrin-stabilising enzyme Factor XIIIa even when labelled with a detectable moiety. The use of suitable protecting groups provides compounds which possess reduced susceptibility to in vivo metabolism especially by peptidases, and are hence useful agents for the diagnosis of thrombosis, embolism, atherosclerosis, inflammation or cancer.

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