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    • 1. 发明申请
    • Compositions comprising silicone pressure sensitive adhesives for delivering oral care substances
    • 包含用于递送口腔护理物质的硅氧烷压敏粘合剂的组合物
    • US20070166244A1
    • 2007-07-19
    • US11334928
    • 2006-01-19
    • Chanchal GhoshStephen KovacsSatyanarayana Majeti
    • Chanchal GhoshStephen KovacsSatyanarayana Majeti
    • A61K8/89
    • A61Q11/00A61K8/892A61K8/898
    • Disclosed are compositions for delivering one or more oral care substances to the oral cavity, comprising: (a) a silicone pressure sensitive adhesive selected from a silicone/resin copolymer with silicon-bonded hydroxyl radicals, a silicone/resin copolymer with endcapped silicon-bonded hydroxyl radicals and mixtures thereof; (b) a plasticizing material; (c) a water-soluble bioadhesive polymer; (d) a hydrophilic surfactant, and (e) at least one oral care substance. The silicone/resin copolymer is prepared by polycondensing a silanol endblocked polydialkylsiloxane and a hydroxyl endblocked silicate resin. The polycondensation product may be further reacted with a trialkylsilyl endcapping agent to reduce the number of hydroxyl radicals in the polymer. Further disclosed are methods of using these compositions, such as for teeth bleaching and whitening applications.
    • 公开了用于将一种或多种口腔护理物质递送到口腔的组合物,其包括:(a)选自具有硅键合羟基的硅氧烷/树脂共聚物的硅氧烷压敏粘合剂,具有封端硅键合的硅树脂/树脂共聚物 羟基自由基及其混合物; (b)增塑材料; (c)水溶性生物粘附聚合物; (d)亲水性表面活性剂,和(e)至少一种口腔护理物质。 通过使硅烷醇封端的聚二烷基硅氧烷和羟基封端的硅酸盐树脂缩聚来制备硅树脂/树脂共聚物。 缩聚产物可以进一步与三烷基甲硅烷基封端剂反应以减少聚合物中羟基自由基的数量。 还公开了使用这些组合物的方法,例如用于牙齿漂白和美白应用。